Standard name
Human Ortholog
Description AP-1-like basic leucine zipper (bZIP) transcriptional activator; involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA; CAD1 has a paralog, YAP1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.89 0.96 0.82 0.63 0.85 0.75 0.67 0.67 0.5 0.54 0.53 0.55 0.98 0.99 0.99 0.7 0.73 0.68 0.77 0.82 0.74 0.86 0.81 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0.09 0.05 0 0 0 0 0 0 0 0 0 0 0.1 0.07 0.12 0 0 0 0 0 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.12 0 0.05 0.28 0.11 0.41 0.51 0.46 0.66 0.6 0.64 0.58 0 0 0 0 0 0 0 0 0 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.05 0.05 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.06 0.18 0.2 0.13 0 0.1 0.06 0.05 0.08 0.08 0.06 0 0 0 0.26 0.2 0.25 0.07 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 1 2
Bud 0 0 1 0 2 2 6 5 8 8 9 5 0 0 0 1 1 1 3 0 0 0 3 6
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 1 3 1 1 0 1 2 2 4 3 3 0 0 0 0 0 0 0 0
Cytoplasm 173 109 127 78 129 190 182 196 102 121 132 124 366 423 459 122 103 73 166 112 118 202 222 271
Endoplasmic Reticulum 2 1 1 0 0 0 0 0 0 0 1 3 1 3 2 5 4 8 2 0 2 0 1 2
Endosome 0 0 4 11 8 1 0 1 0 1 1 1 2 0 1 17 10 13 4 3 3 1 7 23
Golgi 0 0 0 1 1 0 0 0 0 0 0 0 0 0 2 1 2 1 0 0 0 0 1 11
Mitochondria 23 1 7 34 16 105 137 134 134 133 160 131 2 0 2 2 4 4 3 0 5 4 10 17
Nucleus 2 1 1 0 0 4 4 9 4 2 5 4 0 1 0 2 3 1 12 8 8 10 3 0
Nuclear Periphery 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 1 0 1 1 1 0
Nucleolus 0 0 1 1 1 1 1 0 0 0 0 1 0 0 0 1 2 0 0 0 0 0 0 1
Peroxisomes 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 2
SpindlePole 0 0 0 2 0 1 0 0 0 0 0 1 0 0 0 2 4 0 2 0 4 2 4 12
Vac/Vac Membrane 13 7 27 24 20 7 26 18 10 18 21 14 8 0 3 45 29 27 15 6 6 8 9 10
Unique Cell Count 195 114 154 123 151 254 270 294 203 223 249 224 375 426 464 174 142 107 216 137 161 237 274 375
Labelled Cell Count 213 119 169 152 178 313 359 365 260 283 330 288 381 431 472 202 163 130 216 137 161 237 274 375


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 6.0 5.6 4.9 5.3 4.4 4.2 4.1 4.1 3.9 3.6 3.8 6.9 7.6 7.5 7.7 7.5 7.2 6.2 6.7 7.3
Std Deviation (1e-4) 0.6 0.8 1.6 1.6 2.1 1.9 1.4 1.5 1.5 1.1 1.2 1.4 0.8 1.1 1.1 1.8 2.3 1.8 1.1 1.3 1.5
Intensity Change (Log2) – – – -0.18 -0.06 -0.35 -0.39 -0.43 -0.44 -0.53 -0.64 -0.56 0.32 0.44 0.43 0.47 0.43 0.37 0.16 0.26 0.39


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -3.6 0.7 -1.8 -3.4 -3.5 -6.3 -5.7 -6.0 -5.5 6.3 8.1 8.0 -2.6 -2.1 -2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 2.3 1.2 0 0 0 0 0 0 0 0 0 0 2.6 1.8 3.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 5.4 2.0 0 0 0 0 0 0 0 0 0 0 0 -0.8 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.4 -1.0 -5.2 -2.4 -3.8 -3.9 -2.8 -2.7 -3.5 -6.5 -8.9 -8.4 1.8 0.6 1.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1631 0.6669 0.6294 -0.1019 0.5185 0.6586 1.5493 0.605 0.4481 0.7923 0.3623 0.5795 -0.1285 0.3773 0.1279 -0.2077 -0.0144 -0.0435
Actin 0.009 0.0017 0.0023 0.0006 0.0004 0.0006 0.059 0.0002 0.0198 0.0031 0.0432 0.0123 0.0003 0.0016 0.0004 0.0007 0.0008 0.0004
Bud 0.0002 0.0002 0.0003 0.0001 0 0.0001 0.0015 0.0006 0.0022 0.0001 0.0018 0.0031 0.0002 0.0041 0.0008 0.0002 0.0044 0.0001
Bud Neck 0.0014 0.0005 0.0006 0.0006 0.0006 0.0037 0.009 0.0003 0.0018 0.0006 0.0038 0.0024 0.0009 0.0005 0.0007 0.0011 0.002 0.0038
Bud Periphery 0.0002 0.0001 0.0003 0 0 0.0001 0.0021 0.0002 0.0032 0.0001 0.0025 0.0039 0.0001 0.0029 0.0001 0.0001 0.0016 0.0001
Bud Site 0.0019 0.0018 0.0011 0.0002 0.0001 0.0002 0.0124 0.0024 0.0073 0.0003 0.0023 0.0006 0.0064 0.0013 0.0047 0.0002 0.0011 0.0002
Cell Periphery 0.0001 0.0001 0.0001 0 0 0 0.0008 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0 0 0.0001 0
Cytoplasm 0.2985 0.3248 0.2465 0.2221 0.3312 0.2655 0.1768 0.4358 0.3562 0.4303 0.433 0.3108 0.3664 0.3553 0.2417 0.332 0.292 0.2268
Cytoplasmic Foci 0.016 0.0048 0.0133 0.0047 0.007 0.0084 0.1087 0.0062 0.0186 0.0076 0.0167 0.0213 0.0049 0.0033 0.0054 0.0032 0.0307 0.0035
Eisosomes 0.0002 0.0001 0.0002 0.0001 0.0001 0 0.0005 0 0.0001 0.0002 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0065 0.0073 0.005 0.0018 0.0067 0.0025 0.0132 0.0046 0.0067 0.0064 0.0042 0.0034 0.0091 0.0053 0.005 0.0104 0.0034 0.003
Endosome 0.012 0.0051 0.0088 0.0027 0.0082 0.005 0.0852 0.0039 0.0199 0.0213 0.0341 0.0155 0.0068 0.0039 0.0042 0.0051 0.0067 0.0042
Golgi 0.0023 0.0002 0.001 0.0001 0.0001 0.0001 0.0201 0.0001 0.0045 0.0138 0.0375 0.0098 0.0003 0.0002 0.0001 0.0001 0.0008 0.0001
Lipid Particles 0.0098 0.0003 0.0021 0.0002 0.0004 0.0004 0.0606 0.0002 0.0017 0.0415 0.004 0.005 0.0004 0.0002 0.0003 0.0001 0.0001 0.0001
Mitochondria 0.0021 0.0009 0.0023 0.0006 0.0005 0.0008 0.0184 0.0004 0.0029 0.024 0.0087 0.0037 0.0006 0.0031 0.0005 0.0007 0.001 0.0004
None 0.2988 0.2712 0.3636 0.3188 0.4787 0.3087 0.0555 0.1984 0.1616 0.1543 0.1708 0.0847 0.0685 0.1155 0.0974 0.1583 0.1257 0.0986
Nuclear Periphery 0.0205 0.0179 0.0133 0.0108 0.0136 0.0081 0.0426 0.0143 0.0259 0.0089 0.0103 0.0205 0.0331 0.0174 0.0169 0.0169 0.0127 0.0117
Nucleolus 0.003 0.0024 0.0025 0.0023 0.0014 0.0037 0.0025 0.0011 0.0016 0.0006 0.0006 0.0017 0.0023 0.0014 0.0015 0.0012 0.0026 0.0039
Nucleus 0.2767 0.3384 0.293 0.3142 0.126 0.3538 0.2364 0.3168 0.3283 0.2634 0.2106 0.455 0.4661 0.4674 0.5878 0.4541 0.4679 0.6182
Peroxisomes 0.006 0.0004 0.0101 0.0003 0.0001 0.0003 0.0464 0.0001 0.0107 0.0122 0.0018 0.0085 0.0002 0.0005 0.0002 0.0001 0.0036 0.0001
Punctate Nuclear 0.0314 0.0193 0.0311 0.1186 0.0212 0.0362 0.0358 0.0112 0.023 0.0068 0.0099 0.0353 0.0294 0.0132 0.0304 0.0131 0.0406 0.0232
Vacuole 0.003 0.0022 0.0021 0.001 0.003 0.0015 0.0096 0.0027 0.003 0.0028 0.0029 0.002 0.0033 0.0025 0.0014 0.0018 0.0018 0.0013
Vacuole Periphery 0.0006 0.0004 0.0005 0.0002 0.0005 0.0003 0.003 0.0003 0.0009 0.0014 0.0009 0.0006 0.0006 0.0005 0.0003 0.0005 0.0003 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.3532 12.8309 11.3063 16.2801 15.1203 26.8974 23.5141 22.4375 24.4243 20.3173
Translational Efficiency 0.9458 1.1245 1.331 1.1768 0.9146 0.8101 0.8734 1.318 1.0107 1.0146

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
181 143 451 1271 1618 1700 241 1325 1799 1843 692 2596

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 828.44 856.72 1028.10 966.66 883.70 810.68 1118.47 961.77 878.14 814.25 1059.57 964.16
Standard Deviation 100.70 113.60 125.32 156.90 125.94 97.63 124.27 163.03 124.74 99.73 132.17 160.08
Intensity Change Log 2 — 0.048427 0.311511 0.222611 — -0.124424 0.339898 0.122135 — -0.038200 0.326233 0.171626

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000503 0.000797 0.000562 0.004064 0.000151 0.000284 0.001053 0.001471 0.000187 0.000324 0.000733 0.002740
Bud Neck 0.004439 0.004053 0.003500 0.005714 0.001374 0.008271 0.003265 0.005863 0.001682 0.007944 0.003418 0.005790
Bud Site 0.003279 0.006196 0.004978 0.033374 0.005441 0.007473 0.018662 0.039966 0.005224 0.007374 0.009744 0.036739
Cell Periphery 0.000203 0.000152 0.000179 0.000149 0.000099 0.000090 0.000304 0.000103 0.000110 0.000095 0.000222 0.000126
Cytoplasm 0.432197* 0.563612* 0.400934* 0.585124* 0.778814* 0.546673* 0.317472* 0.601079* 0.743941* 0.547988* 0.371867* 0.593268*
Cytoplasmic Foci 0.131610 0.152302 0.017441 0.045888 0.094246 0.107139 0.019175 0.037784 0.098005 0.110644 0.018045 0.041752
Eisosomes 0.000087 0.000074 0.000051 0.000038 0.000014 0.000051 0.000103 0.000029 0.000022 0.000053 0.000069 0.000034
Endoplasmic Reticulum 0.004275 0.003986 0.008735 0.002400 0.003013 0.001387 0.011849 0.001702 0.003140 0.001589 0.009819 0.002044
Endosome 0.008731 0.012271 0.004259 0.007961 0.004820 0.007593 0.008619 0.012162 0.005214 0.007956 0.005778 0.010105
Golgi 0.003035 0.000731 0.000125 0.003699 0.001711 0.001415 0.000193 0.005779 0.001845 0.001362 0.000149 0.004760
Lipid Particles 0.007487 0.007911 0.002458 0.001966 0.001850 0.004615 0.005751 0.002620 0.002417 0.004871 0.003605 0.002300
Mitochondria 0.006056 0.001196 0.000588 0.004383 0.001276 0.005768 0.000841 0.005525 0.001757 0.005414 0.000676 0.004966
Mitotic Spindle 0.001841 0.003183 0.003966 0.048021 0.002096 0.010907 0.008257 0.060333 0.002070 0.010308 0.005461 0.054305
None 0.004774 0.005535 0.004361 0.002080 0.004798 0.003192 0.004219 0.004770 0.004796 0.003374 0.004312 0.003453
Nuclear Periphery 0.001703 0.001502 0.003846 0.002099 0.000288 0.001091 0.003298 0.001040 0.000430 0.001123 0.003655 0.001558
Nuclear Periphery Foci 0.006881 0.009102 0.007320 0.008421 0.001534 0.000958 0.013104 0.004360 0.002072 0.001590 0.009334 0.006348
Nucleolus 0.002304 0.001831 0.000609 0.000234 0.000432 0.001418 0.000567 0.001465 0.000620 0.001450 0.000594 0.000862
Nucleus 0.329446* 0.136627* 0.420988* 0.091324 0.066890 0.240534* 0.354429* 0.087331 0.093306 0.232471* 0.397808* 0.089286
Peroxisomes 0.002269 0.004337 0.000254 0.006464 0.000395 0.002989 0.000498 0.004860 0.000583 0.003094 0.000339 0.005645
Vacuole 0.048337 0.083275 0.114645 0.145622 0.026220 0.046603 0.227984* 0.116154 0.028445 0.049448 0.154117 0.130582
Vacuole Periphery 0.000544 0.001328 0.000198 0.000974 0.004536 0.001546 0.000357 0.005604 0.004135 0.001529 0.000254 0.003337

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.02 -1.84 -2.05 -1.49 -1.66 -2.15 -9.92 -4.45 -3.22 1.65 -2.20 -13.29 -3.49 -3.02 -1.29
Bud Neck 0.18 -0.38 -0.11 -0.79 0.80 -8.40 -6.90 -6.72 4.58 1.52 -7.91 -7.75 -6.60 4.26 1.65
Bud Site -2.42 -2.60 -7.33 -5.61 -5.19 -1.93 -1.50 -6.54 -5.31 -2.41 -2.21 -2.04 -9.29 -7.08 -5.58
Cell Periphery 2.08 0.28 4.18 1.71 5.63 0.80 -6.77 2.19 2.00 9.22 1.39 -7.43 1.30 -0.27 10.74
Cytoplasm -3.71 5.31 -2.69 2.30 -12.25 28.27 38.85 29.09 4.02 -17.41 23.72 43.52 31.56 5.98 -19.69
Cytoplasmic Foci -1.06 10.33 8.24 7.78 -9.91 -2.88 23.76 17.35 19.28 -8.44 -2.86 26.23 19.19 20.84 -12.58
Eisosomes 1.26 2.79 6.74 4.89 7.14 -11.27 -11.94 -10.28 6.63 9.79 -9.54 -15.26 -5.47 6.32 12.36
Endoplasmic Reticulum 0.46 -7.00 3.47 2.32 12.05 3.64 -9.95 3.72 -0.16 12.48 3.81 -12.83 3.44 -1.22 17.16
Endosome -0.88 3.66 3.80 3.43 0.57 -4.22 -3.08 -0.83 2.35 1.54 -4.11 -0.58 0.49 4.26 1.05
Golgi 0.91 1.15 0.67 -0.99 -2.13 1.16 9.87 -0.10 -0.80 -3.64 1.42 6.23 0.79 -0.44 -4.04
Lipid Particles 0.05 5.22 5.19 2.39 -0.31 -4.84 -4.81 -0.33 3.87 3.64 -4.30 -2.85 0.03 4.26 2.76
Mitochondria 1.00 1.10 0.90 -0.47 -1.09 -4.17 2.95 -0.81 3.06 -1.64 -3.38 2.11 0.03 3.35 -1.93
Mitotic Spindle -1.13 -2.09 -8.49 -7.00 -7.22 -4.44 -2.00 -10.45 -7.75 -8.03 -4.53 -2.96 -13.51 -9.08 -11.11
None -0.27 0.87 3.26 2.38 2.83 2.09 1.88 1.41 -1.61 -1.06 2.06 1.45 2.58 1.13 1.58
Nuclear Periphery 0.41 -4.19 -0.63 -0.91 3.71 -11.26 -16.41 -11.06 -4.68 8.83 -8.55 -10.31 -8.19 -3.99 5.91
Nuclear Periphery Foci -0.09 0.00 0.09 0.14 0.12 2.81 -7.20 -5.96 -7.18 4.97 1.38 -7.33 -7.52 -7.56 3.11
Nucleolus 0.81 3.38 3.77 1.86 1.49 -4.92 -1.31 -1.73 2.74 0.23 -4.05 -0.53 0.24 4.13 0.71
Nucleus 7.18 -4.57 10.25 2.60 23.72 -28.33 -17.45 -9.53 19.02 14.96 -21.84 -28.44 -3.20 21.24 27.85
Peroxisomes -1.73 3.95 -0.36 1.33 -3.38 -7.37 -0.67 -3.83 1.32 -3.55 -7.37 3.20 -4.30 1.06 -4.88
Vacuole -3.02 -9.38 -20.68 -12.48 -8.33 -9.07 -15.05 -31.08 -27.22 1.40 -9.02 -20.20 -44.32 -38.20 -5.25
Vacuole Periphery -2.01 3.30 1.21 2.47 -1.64 3.48 5.37 3.01 -0.30 -2.73 3.36 5.45 4.05 1.00 -2.99
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description AP-1-like basic leucine zipper (bZIP) transcriptional activator; involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA; CAD1 has a paralog, YAP1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (92%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Cad1

Cad1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cad1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available