Standard name
Human Ortholog
Description Sorting nexin; involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.1 0.09 0 0.05 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.05 0 0 0 0 – 0.09 0.05 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.17 0.21 0.2 0.28 0.19 0.24 0.22 – 0.24 0.27 0.22 0.3 0.22 0.25 0.18 0.13 0.15 0.18 0.06 0.07 0.07 0 0.13 0.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.61 0.59 0.43 0.46 0.56 0.56 0.46 – 0.42 0.38 0.27 0.28 0.55 0.56 0.71 0.54 0.63 0.62 0.63 0.66 0.59 0.68 0.56 0.64
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0 0 0 0 0 0.06 – 0.18 0.09 0.43 0.26 0 0 0 0 0 0 0 0 0.09 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.06 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.3 0.25 0.38 0.32 0.26 0.24 0.31 – 0.22 0.29 0.15 0.23 0.28 0.34 0.36 0.41 0.37 0.37 0.19 0.13 0.12 0.13 0.13 0.12
Vac/Vac Membrane 0.05 0.2 0.11 0.08 0.1 0.08 0.06 – 0.1 0.08 0.07 0.06 0.18 0.06 0.07 0.16 0.14 0.17 0.05 0.06 0.05 0.06 0.07 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 4 8 10 7 12 13 – 5 8 1 9 1 6 3 11 3 13 1 2 2 0 1 3
Bud 5 2 4 3 6 8 12 – 16 16 14 13 1 3 2 1 1 5 0 2 0 0 1 1
Bud Neck 1 0 0 0 0 2 3 – 0 1 0 1 0 0 1 0 0 0 2 0 0 1 2 1
Bud Site 0 0 1 0 0 0 1 – 0 3 5 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 1 1 0 1 0 0 0 2 1 0 0 0 0 0 0 0
Cytoplasm 30 33 16 32 32 57 66 – 44 81 46 86 26 55 49 51 55 63 11 11 9 4 34 31
Endoplasmic Reticulum 2 0 0 4 3 6 8 – 1 3 4 8 3 1 3 11 10 15 0 0 1 0 2 1
Endosome 105 93 35 52 96 133 140 – 77 114 55 81 65 124 189 204 226 220 121 113 71 79 145 209
Golgi 0 0 2 0 0 1 0 – 0 0 0 0 1 0 0 7 4 6 3 0 0 0 0 1
Mitochondria 12 1 0 0 1 9 17 – 33 28 89 76 0 0 0 7 6 9 3 2 11 4 8 9
Nucleus 0 1 0 0 1 1 3 – 1 5 1 1 0 0 1 1 0 0 0 0 0 0 2 0
Nuclear Periphery 3 0 0 0 0 0 0 – 0 0 0 0 1 0 0 1 0 1 0 0 0 0 1 2
Nucleolus 10 8 1 3 4 3 6 – 2 2 9 6 3 6 2 17 15 21 0 0 0 1 1 1
Peroxisomes 4 0 0 1 0 2 5 – 1 4 3 5 0 2 9 5 6 1 0 0 0 0 0 0
SpindlePole 52 40 31 36 45 57 94 – 40 87 31 67 33 75 95 154 135 129 35 21 14 15 32 39
Vac/Vac Membrane 8 32 9 9 17 19 18 – 18 23 15 18 21 13 19 62 52 59 9 10 6 6 19 17
Unique Cell Count 173 158 82 114 170 237 305 182 304 206 287 119 222 265 378 361 352 192 171 121 117 260 326
Labelled Cell Count 236 214 107 150 212 310 386 239 376 273 373 155 285 373 534 514 542 192 171 121 117 260 326


Cytoplasm, Endosome, Lipid Particles

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 7.5 6.8 6.8 7.5 6.7 6.8 – 5.7 6.0 5.2 5.6 7.2 7.4 7.4 10.3 9.8 9.3 6.4 6.8 7.0
Std Deviation (1e-4) 0.7 0.8 1.1 1.3 1.3 1.0 1.2 – 1.0 1.0 0.9 0.9 1.3 1.0 1.1 2.3 1.8 1.9 1.3 1.3 1.3
Intensity Change (Log2) – – – -0.01 0.13 -0.03 -0.01 – -0.26 -0.2 -0.39 -0.29 0.08 0.11 0.12 0.58 0.52 0.44 -0.09 0.0 0.04


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.2 0 -1.5 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 1.1 0 0.6 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 -0.1 0.8 0.4 – 0.8 1.3 0.5 1.9 0.4 1.0 -0.2 -1.4 -1.0 -0.3
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0.4 2.1 2.1 0.5 – -0.1 -0.9 -2.6 -2.5 1.7 2.0 4.7 1.9 3.3 3.3
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 4.1 2.9 7.2 5.2 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole -0.9 -1.8 -2.4 -1.2 – -2.7 -1.6 -4.2 -2.6 -1.5 -0.7 -0.3 0.5 -0.1 -0.2
Vacuole -0.7 -0.2 -0.8 -1.6 – -0.3 -1.0 -1.0 -1.4 1.3 -1.5 -1.1 1.2 0.8 1.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.0638 0.7379 0.4164 0.1558 0.4066 0.8236 1.2656 2.1577 1.7655 1.1998 1.6995 1.7233 0.1915 1.1156 0.7899 0.7547 0.2516 0.5947
Actin 0.0336 0.0003 0.0271 0.0051 0.018 0.0007 0.0253 0.0002 0.0064 0.0018 0.0045 0.0002 0.0147 0.0001 0.0141 0.0137 0 0.0063
Bud 0.0008 0.0001 0.0019 0.0002 0.0003 0.0003 0.0005 0.0004 0.0006 0.0003 0.0008 0.0001 0.0007 0.0003 0.0004 0.0011 0 0.0001
Bud Neck 0.0022 0.0002 0.001 0.0033 0.0005 0.001 0.0055 0.0007 0.001 0.0003 0.0008 0.0004 0.0026 0.0003 0.001 0.0042 0.0001 0.0159
Bud Periphery 0.0011 0.0001 0.0009 0.0003 0.0004 0.0003 0.0012 0.0008 0.0006 0.0002 0.0004 0.0001 0.0007 0.0005 0.0005 0.0008 0 0.0001
Bud Site 0.0057 0.001 0.0031 0.0017 0.001 0.0003 0.0027 0.0024 0.0015 0.0003 0.0015 0.0001 0.007 0.0014 0.0029 0.1317 0.0001 0.0002
Cell Periphery 0.0004 0.0002 0.0002 0.0003 0.0001 0.0001 0.0003 0.0002 0.0002 0.0001 0.0001 0 0.0002 0.0001 0.0002 0.0009 0 0
Cytoplasm 0.0616 0.1665 0.1491 0.1161 0.1497 0.2538 0.1442 0.1746 0.1415 0.1413 0.2551 0.1998 0.1815 0.2499 0.1923 0.1279 0.2277 0.31
Cytoplasmic Foci 0.2095 0.3188 0.2334 0.1729 0.2277 0.1867 0.1951 0.2953 0.2544 0.2362 0.2202 0.2745 0.2076 0.2392 0.2337 0.1708 0.1698 0.2124
Eisosomes 0.0006 0 0.0002 0.0002 0.0001 0 0.0003 0.0001 0.0001 0 0.0001 0 0.0003 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0077 0.0049 0.0057 0.0048 0.002 0.0048 0.0091 0.0025 0.0035 0.0037 0.0027 0.0027 0.0059 0.0082 0.0048 0.0012 0.0007 0.0051
Endosome 0.4904 0.4023 0.4157 0.518 0.3483 0.4347 0.4368 0.4068 0.4325 0.447 0.2924 0.4187 0.3674 0.3818 0.4316 0.2958 0.5346 0.3596
Golgi 0.0241 0.0124 0.0322 0.0251 0.0375 0.0164 0.0189 0.0115 0.0176 0.0133 0.028 0.0133 0.0123 0.0101 0.0211 0.0384 0.0109 0.0107
Lipid Particles 0.0523 0.0223 0.0292 0.0108 0.043 0.0201 0.0494 0.0187 0.02 0.0057 0.0173 0.013 0.0371 0.0143 0.0264 0.0789 0.0379 0.0133
Mitochondria 0.0093 0.0123 0.005 0.0345 0.0713 0.0242 0.0068 0.0008 0.0072 0.0057 0.0036 0.0026 0.0077 0.0069 0.0083 0.0035 0.0004 0.0008
None 0.0467 0.0361 0.0505 0.0579 0.0464 0.0339 0.0658 0.0574 0.0694 0.0862 0.1117 0.0512 0.1112 0.0562 0.0324 0.002 0.001 0.04
Nuclear Periphery 0.0035 0.001 0.0023 0.0012 0.0004 0.0012 0.0041 0.001 0.0014 0.006 0.0013 0.0009 0.004 0.0027 0.0014 0.0006 0.0004 0.003
Nucleolus 0.0016 0.0002 0.0008 0.0005 0.0001 0.0001 0.0013 0.002 0.0005 0.0002 0.0004 0.0001 0.0007 0.0013 0.0003 0.0002 0 0.0001
Nucleus 0.0013 0.0006 0.0011 0.0007 0.0003 0.0007 0.0011 0.0011 0.001 0.0015 0.001 0.0006 0.0089 0.0009 0.0007 0.0007 0.0002 0.0013
Peroxisomes 0.0234 0.0067 0.0195 0.0137 0.0437 0.0028 0.0106 0.0073 0.0179 0.0221 0.0361 0.0051 0.0056 0.0082 0.0088 0.0954 0.0023 0.0039
Punctate Nuclear 0.003 0.0027 0.0051 0.0005 0.0012 0.0008 0.0036 0.0026 0.0034 0.0016 0.0067 0.0015 0.0056 0.001 0.001 0.0011 0.0003 0.0015
Vacuole 0.0181 0.0098 0.0133 0.0281 0.0062 0.0136 0.0147 0.0116 0.0166 0.0209 0.0126 0.0107 0.0164 0.0145 0.0155 0.026 0.0102 0.0132
Vacuole Periphery 0.0029 0.0014 0.0027 0.0041 0.0016 0.0035 0.0026 0.002 0.0028 0.0056 0.0029 0.0044 0.0019 0.0021 0.0025 0.0051 0.0034 0.0025

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.5817 5.7775 7.4051 8.8944 5.7133 5.8722 8.0986 10.036 7.6709 10.4018
Translational Efficiency 1.0782 0.9036 0.7443 0.6128 0.9221 1.1961 0.8334 0.7023 0.8635 0.7302

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2327 1447 1612 1717 1727 1476 2014 89 4054 2923 3626 1806

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 676.66 792.74 1034.77 1006.68 794.35 797.46 995.55 964.38 726.80 795.12 1012.99 1004.60
Standard Deviation 82.71 119.40 136.64 134.42 94.02 100.74 114.98 142.35 105.26 110.40 126.58 135.14
Intensity Change Log 2 — 0.228417 0.612807 0.573102 — 0.005637 0.325719 0.279827 — 0.112401 0.464900 0.422165

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001292 0.000252 0.000309 0.000795 0.000176 0.000111 0.000131 0.000214 0.000816 0.000181 0.000210 0.000766
Bud Neck 0.046585 0.008261 0.019844 0.011367 0.017262 0.009884 0.014927 0.020564 0.034094 0.009081 0.017113 0.011820
Bud Site 0.031296 0.014958 0.030246 0.051688 0.011958 0.008556 0.017460 0.028510 0.023058 0.011725 0.023144 0.050546
Cell Periphery 0.000234 0.000051 0.000138 0.000046 0.000058 0.000041 0.000037 0.000142 0.000159 0.000046 0.000082 0.000051
Cytoplasm 0.065639 0.044668 0.018850 0.279881* 0.033235 0.028092 0.132270* 0.175587* 0.051835 0.036298 0.081847 0.274741*
Cytoplasmic Foci 0.354004* 0.287328* 0.270337* 0.203263* 0.215911* 0.221293* 0.159942 0.141599 0.295177* 0.253983* 0.209020* 0.200224*
Eisosomes 0.000169 0.000029 0.000038 0.000014 0.000033 0.000023 0.000011 0.000049 0.000111 0.000026 0.000023 0.000016
Endoplasmic Reticulum 0.000968 0.000360 0.000396 0.000346 0.001203 0.000459 0.000874 0.000891 0.001068 0.000410 0.000662 0.000373
Endosome 0.292281* 0.495560* 0.275441* 0.141464 0.576537* 0.542600* 0.324582* 0.181437 0.413374* 0.519313* 0.302736* 0.143434
Golgi 0.061761 0.035258 0.018668 0.007478 0.025738 0.035951 0.003664 0.001947 0.046415 0.035608 0.010334 0.007206
Lipid Particles 0.024403 0.015213 0.027302 0.004527 0.017810 0.016149 0.004656 0.004096 0.021594 0.015686 0.014723 0.004506
Mitochondria 0.020419 0.004784 0.002355 0.001688 0.004094 0.008218 0.000982 0.000581 0.013465 0.006518 0.001592 0.001634
Mitotic Spindle 0.003722 0.016531 0.170791* 0.075164 0.010211 0.021571 0.037581 0.014714 0.006486 0.019076 0.096802 0.072185
None 0.001946 0.000628 0.000141 0.000281 0.000356 0.000710 0.000315 0.000262 0.001269 0.000669 0.000238 0.000280
Nuclear Periphery 0.000081 0.000137 0.002171 0.000261 0.000210 0.000276 0.001124 0.000385 0.000136 0.000207 0.001589 0.000267
Nuclear Periphery Foci 0.002177 0.004310 0.049312 0.002112 0.007352 0.004092 0.005115 0.002319 0.004382 0.004200 0.024763 0.002122
Nucleolus 0.001111 0.001316 0.005474 0.000450 0.001422 0.001796 0.001892 0.002400 0.001243 0.001558 0.003485 0.000546
Nucleus 0.003501 0.001223 0.002248 0.004321 0.002179 0.002355 0.007492 0.010363 0.002938 0.001794 0.005161 0.004618
Peroxisomes 0.064264 0.030801 0.039389 0.026964 0.026500 0.028326 0.009134 0.012227 0.048176 0.029551 0.022584 0.026238
Vacuole 0.019264 0.033371 0.059774 0.184866 0.043545 0.061098 0.271083* 0.396208* 0.029608 0.047372 0.177142 0.195281
Vacuole Periphery 0.004884 0.004962 0.006777 0.003022 0.004209 0.008397 0.006730 0.005507 0.004596 0.006697 0.006751 0.003145

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.95 2.75 1.82 -4.64 -4.02 1.26 0.77 -0.23 -1.38 -0.95 3.12 2.93 0.93 -6.08 -5.65
Bud Neck 14.40 9.33 13.75 -2.61 8.49 3.62 0.72 -0.53 -1.72 -0.77 14.06 8.95 13.03 -2.35 7.28
Bud Site 6.95 -0.10 -3.41 -10.23 -3.41 2.31 -3.36 -1.97 -2.39 -1.27 7.78 -0.48 -7.39 -13.07 -7.25
Cell Periphery 8.16 3.45 8.66 1.38 7.13 1.77 2.64 -1.42 -1.89 -2.01 8.26 5.06 8.56 -0.17 5.11
Cytoplasm 4.51 11.55 -32.11 -34.43 -39.28 1.42 -20.09 -6.59 -6.78 -2.12 5.16 -10.81 -35.56 -37.73 -28.50
Cytoplasmic Foci 8.72 11.74 26.82 17.41 13.52 -0.81 10.20 5.71 6.04 1.79 7.62 18.09 22.93 15.99 7.20
Eisosomes 8.07 7.61 9.11 6.84 9.35 3.40 9.23 -1.36 -2.73 -4.50 8.44 8.83 9.70 7.53 6.16
Endoplasmic Reticulum 2.80 2.44 3.00 0.61 1.92 2.75 0.91 1.44 -1.80 0.37 3.87 1.78 4.20 1.05 2.32
Endosome -20.92 3.67 27.41* 46.37* 22.82* 3.33 29.86 18.86 17.19 6.57 -13.91 20.20 48.99* 62.56* 30.87*
Golgi 9.68 18.23 25.03 17.56 11.24 -4.38 16.85 17.25 17.55 3.01 5.83 24.63 27.73 22.77 7.11
Lipid Particles 4.24 -0.63 11.99 7.33 10.74 0.62 8.06 8.12 6.83 1.67 3.56 5.13 14.18 9.59 9.90
Mitochondria 9.82 12.27 13.20 5.10 2.70 -3.19 3.94 4.52 7.50 2.61 6.40 13.03 13.32 8.29 1.63
Mitotic Spindle -6.63 -25.52* -15.06 -11.18 12.71 -4.24 -9.59 -0.47 0.77 2.79 -7.71 -25.95 -14.32 -10.74 5.72
None 2.65 5.20 4.65 0.85 -2.21 -1.17 0.75 1.49 2.02 1.29 2.07 5.09 4.63 1.66 -0.74
Nuclear Periphery -2.50 -15.49 -12.94 -9.57 12.31 -0.97 -6.20 -2.71 -1.36 5.11 -2.01 -13.62 -10.33 -6.37 10.46
Nuclear Periphery Foci -2.77 -15.77 -0.48 2.43 15.61 2.25 1.11 4.25 2.82 4.58 -0.24 -13.31 2.83 3.03 15.19
Nucleolus -0.90 -6.55 2.35 1.90 7.40 -1.07 -1.66 -0.34 0.21 0.33 -1.52 -6.71 2.74 3.51 9.26
Nucleus 3.03 0.57 -5.80 -11.97 -7.77 -0.43 -8.22 -3.81 -3.63 0.10 1.88 -6.14 -8.25 -10.95 -1.89
Peroxisomes 10.57 8.37 16.10 5.28 7.79 -0.77 11.51 3.96 4.21 -1.14 8.92 14.26 14.85 6.17 1.88
Vacuole -5.92 -15.13 -38.76 -34.84 -28.40 -3.84 -38.38 -12.54 -11.92 -4.60 -7.05 -38.65 -38.43 -33.96 -10.02
Vacuole Periphery -0.09 -2.47 5.29 5.72 7.87 -5.59 -3.62 0.09 2.46 1.18 -4.21 -3.97 5.83 9.54 10.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Sorting nexin; involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p
Localization
Cell Percentages endosome (69%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Snx41

Snx41


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Snx41-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available