Standard name
Human Ortholog
Description Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0.05 0.15 0.09 0.08 0.06 0.1 0.08 0.07
Bud 0 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0.06 0.07 0.07 0.08
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.11 0.11 0.07 0.09 0.06 0.05 0.05 – 0.06 0.07 0 0 0.16 0.18 0.2 0.13 0.16 0.15 0.06 0.14 0.15 0.25 0.32 0.24
Cytoplasm 0.9 0.89 0.94 0.99 0.97 0.91 0.89 – 0.77 0.76 0.71 0.82 0.98 0.98 0.98 0.8 0.71 0.69 0.36 0.24 0.36 0.28 0.27 0.35
Endoplasmic Reticulum 0 0.06 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0.05 0.24 0.17 0.09 0.07 0.09 0.08
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0.1 – 0.25 0.23 0.34 0.2 0 0 0 0 0.05 0.08 0.09 0.17 0.17 0.11 0.1 0.08
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0 0.07 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 5 2 1 5 6 3 – 5 9 3 6 10 5 7 7 2 6 19 17 16 22 29 27
Bud 7 1 0 0 4 3 6 – 18 13 22 9 10 7 7 0 0 2 1 1 3 1 4 8
Bud Neck 3 0 16 11 15 9 7 – 7 5 0 2 0 1 1 0 0 0 14 15 16 15 23 29
Bud Site 0 0 0 0 0 0 2 – 2 0 3 0 0 0 1 0 0 0 – – – – – –
Cell Periphery 21 15 19 23 22 24 22 – 25 28 13 15 71 90 115 12 6 6 14 31 42 56 112 92
Cytoplasm 169 125 242 267 348 450 406 – 322 314 306 311 435 498 554 72 27 27 81 54 100 63 92 132
Endoplasmic Reticulum 8 8 4 0 2 7 7 – 2 6 1 5 0 1 4 3 2 2 54 37 23 16 30 28
Endosome 0 0 1 0 0 0 0 – 0 0 0 3 0 0 0 0 0 0 3 5 3 2 0 1
Golgi 0 0 1 0 0 0 0 – 0 0 0 0 0 0 1 2 0 0 0 1 2 3 0 1
Mitochondria 4 2 1 2 2 36 45 – 105 93 147 75 2 1 2 3 2 3 19 37 46 24 33 31
Nucleus 0 0 0 1 3 5 2 – 0 3 2 4 1 0 2 3 3 1 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 2 0 0 2 0 0 1 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 4 2 1 5 9 – 3 7 9 7 0 0 0 0 0 0 1 0 0 0 1 0
Vac/Vac Membrane 0 0 0 1 1 1 1 – 2 1 11 4 0 2 0 0 0 1 11 19 8 15 12 16
Unique Cell Count 187 140 257 270 360 492 456 420 412 429 379 444 507 566 90 38 39 225 227 277 228 346 380
Labelled Cell Count 216 156 290 308 403 546 510 491 479 520 441 529 607 694 102 43 48 225 227 277 228 346 380


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 5.4 5.3 5.0 5.4 4.3 4.4 – 3.9 3.9 3.8 4.5 4.7 4.7 5.0 6.4 7.5 6.5 4.3 4.5 4.8
Std Deviation (1e-4) 0.5 0.9 0.8 1.1 1.3 0.9 1.2 – 1.2 0.8 1.0 1.1 0.9 0.7 0.9 1.1 1.8 1.5 1.2 1.1 1.3
Intensity Change (Log2) – – – -0.09 0.01 -0.31 -0.27 – -0.44 -0.43 -0.47 -0.23 -0.16 -0.16 -0.08 0.27 0.49 0.3 -0.29 -0.25 -0.13

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck -1.1 -1.2 0 0 – 0 0 0 0 0 0 -5.7 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.5 -0.6 0 0 – 0 0 0 0 0 0 4.7 1.7 0 0
Cytoplasm 3.0 1.5 -1.3 -2.3 – -5.9 -6.0 -7.2 -4.4 2.7 3.0 2.8 -3.9 -4.7 -5.0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.5309 0.7375 0.2883 0.2644 0.5606 1.2249 0.9387 1.0113 0.7952 0.8103 1.0292 1.0377 0.4469 0.6023 0.3179 0.357 0.4746 0.3228
Actin 0.0248 0.009 0.0132 0.004 0.0445 0.0118 0.0618 0.0093 0.0115 0.0148 0.0413 0.0142 0.0312 0.0099 0.0282 0.0265 0.0703 0.0117
Bud 0.0022 0.0029 0.0018 0.0305 0.0043 0.0011 0.0008 0.0017 0.0021 0.0046 0.0005 0.0046 0.0005 0.002 0.0021 0.0011 0.0039 0.002
Bud Neck 0.0148 0.0029 0.0101 0.0051 0.0253 0.0092 0.0019 0.0024 0.0076 0.003 0.0043 0.0211 0.0048 0.003 0.0035 0.0101 0.0142 0.0152
Bud Periphery 0.0048 0.0044 0.0041 0.0079 0.0187 0.0045 0.0021 0.0053 0.0089 0.0193 0.002 0.0135 0.0014 0.0053 0.0072 0.0041 0.0192 0.0061
Bud Site 0.0145 0.0581 0.035 0.0155 0.0379 0.0011 0.0055 0.0699 0.0336 0.0124 0.0085 0.0013 0.0181 0.1163 0.0225 0.0061 0.0193 0.0021
Cell Periphery 0.019 0.0209 0.0153 0.0095 0.0159 0.0161 0.0322 0.0403 0.0253 0.0111 0.0116 0.0212 0.0361 0.0201 0.0236 0.0259 0.0406 0.0113
Cytoplasm 0.4376 0.5394 0.501 0.524 0.3313 0.4452 0.574 0.6496 0.6233 0.5834 0.5911 0.6891 0.5052 0.4426 0.5886 0.7112 0.5146 0.6448
Cytoplasmic Foci 0.0274 0.0116 0.0126 0.0065 0.0298 0.0159 0.024 0.0058 0.0149 0.0076 0.0194 0.0055 0.0217 0.0095 0.0101 0.0087 0.0085 0.0072
Eisosomes 0.0021 0.0022 0.0012 0.0004 0.0017 0.0007 0.0008 0.0007 0.0006 0.0008 0.0003 0.0003 0.0026 0.0015 0.0008 0.0004 0.0046 0.0003
Endoplasmic Reticulum 0.013 0.0078 0.011 0.0113 0.0121 0.0075 0.0135 0.0134 0.0076 0.0201 0.0042 0.0057 0.0132 0.0057 0.0165 0.0183 0.005 0.0071
Endosome 0.0188 0.0035 0.0051 0.0032 0.0218 0.0069 0.0193 0.0014 0.0087 0.0086 0.0218 0.0067 0.011 0.0009 0.0021 0.0205 0.0042 0.0049
Golgi 0.0096 0.0015 0.0028 0.0025 0.0209 0.0038 0.0068 0.0031 0.0015 0.002 0.0201 0.002 0.0037 0.0005 0.0015 0.0052 0.004 0.0011
Lipid Particles 0.0125 0.0017 0.0028 0.0032 0.0261 0.0045 0.0061 0.001 0.0037 0.0044 0.0277 0.0046 0.0085 0.0016 0.0024 0.0059 0.0034 0.0013
Mitochondria 0.0193 0.0012 0.0034 0.02 0.0066 0.0087 0.0093 0.0005 0.0005 0.0008 0.0059 0.0019 0.0051 0.0003 0.0007 0.0024 0.0028 0.0015
None 0.3452 0.3222 0.368 0.3358 0.3454 0.4451 0.2009 0.1918 0.2416 0.2939 0.1867 0.1934 0.3044 0.3753 0.2735 0.1341 0.2485 0.2687
Nuclear Periphery 0.004 0.0009 0.0009 0.0015 0.0051 0.0022 0.0229 0.0003 0.0006 0.004 0.0103 0.0087 0.0118 0.0004 0.0007 0.0092 0.0093 0.0033
Nucleolus 0.0038 0.0008 0.0015 0.0013 0.0019 0.0018 0.0004 0.0002 0.0004 0.0004 0.0003 0.0003 0.0009 0.0005 0.0006 0.0003 0.0027 0.0004
Nucleus 0.0041 0.0023 0.002 0.0083 0.0084 0.0044 0.0082 0.0006 0.0009 0.0019 0.0035 0.0017 0.0035 0.001 0.0014 0.0018 0.0062 0.0034
Peroxisomes 0.0071 0.0005 0.0023 0.001 0.0073 0.0016 0.002 0.0002 0.0015 0.0005 0.0287 0.0005 0.0064 0.0003 0.0092 0.0008 0.0056 0.0003
Punctate Nuclear 0.008 0.0019 0.0019 0.0014 0.0309 0.0053 0.0027 0.0002 0.0015 0.0023 0.01 0.0008 0.0045 0.001 0.0009 0.0027 0.005 0.0024
Vacuole 0.0066 0.0037 0.0036 0.0063 0.0034 0.0022 0.0026 0.002 0.0034 0.0035 0.0012 0.002 0.0048 0.0023 0.0035 0.0042 0.007 0.0035
Vacuole Periphery 0.0009 0.0006 0.0003 0.0007 0.0007 0.0005 0.0022 0.0001 0.0004 0.0005 0.0006 0.0011 0.0006 0.0001 0.0002 0.0007 0.001 0.0015

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.9836 6.0117 5.8335 12.4321 8.7192 6.7212 13.6764 12.3075 14.7432 10.7534
Translational Efficiency 0.8414 0.7086 1.0186 0.5299 0.5343 1.6436 0.5382 0.7343 0.7324 0.8242

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
235 903 1699 1526 1399 1015 2240 553 1634 1918 3939 2079

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 673.39 801.18 853.80 900.51 677.39 762.81 869.81 911.86 676.81 780.87 862.90 903.53
Standard Deviation 68.10 100.50 97.62 113.33 108.98 97.13 102.00 128.32 104.11 100.57 100.45 117.61
Intensity Change Log 2 — 0.250684 0.342456 0.419300 — 0.171337 0.360714 0.428826 — 0.211439 0.351641 0.424085

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000561 0.002650 0.001429 0.010450 0.001361 0.003631 0.000854 0.017381 0.001246 0.003169 0.001102 0.012294
Bud Neck 0.058312 0.058482 0.007414 0.017248 0.036120 0.077969 0.009467 0.012334 0.039312 0.068794 0.008582 0.015941
Bud Site 0.006582 0.021797 0.019628 0.068187 0.009008 0.038839 0.017877 0.066116 0.008659 0.030816 0.018633 0.067636
Cell Periphery 0.002370 0.001749 0.001183 0.005480 0.001308 0.001716 0.000871 0.009802 0.001461 0.001731 0.001006 0.006630
Cytoplasm 0.551310 0.471793 0.482502 0.416485 0.486011 0.416732 0.568734 0.362398 0.495402 0.442655 0.531540 0.402099
Cytoplasmic Foci 0.170582 0.209178 0.047448 0.040892 0.214351 0.224891 0.042602 0.058355 0.208056 0.217494 0.044692 0.045537
Eisosomes 0.004554 0.003743 0.000259 0.003817 0.004687 0.004212 0.000305 0.006917 0.004668 0.003991 0.000285 0.004642
Endoplasmic Reticulum 0.002438 0.002263 0.009987 0.008186 0.003560 0.001479 0.001901 0.012173 0.003398 0.001848 0.005389 0.009246
Endosome 0.014622 0.024325 0.002746 0.004948 0.016387 0.029611 0.003007 0.005884 0.016134 0.027123 0.002895 0.005197
Golgi 0.005709 0.010658 0.000279 0.002902 0.009446 0.019037 0.000844 0.003531 0.008909 0.015092 0.000600 0.003069
Lipid Particles 0.018301 0.012266 0.002952 0.004088 0.026487 0.013597 0.001726 0.005053 0.025310 0.012970 0.002255 0.004345
Mitochondria 0.005593 0.004670 0.000286 0.002323 0.004496 0.013766 0.000579 0.001199 0.004653 0.009484 0.000452 0.002024
Mitotic Spindle 0.000026 0.002658 0.001050 0.012557 0.000504 0.003649 0.002809 0.006317 0.000435 0.003182 0.002050 0.010897
None 0.001520 0.001263 0.001461 0.000627 0.006989 0.000417 0.001541 0.000693 0.006202 0.000815 0.001506 0.000645
Nuclear Periphery 0.000214 0.000129 0.000620 0.000559 0.000484 0.000093 0.000526 0.000879 0.000445 0.000110 0.000567 0.000644
Nuclear Periphery Foci 0.000444 0.000506 0.003805 0.002496 0.001131 0.000286 0.001036 0.004569 0.001032 0.000389 0.002230 0.003047
Nucleolus 0.000467 0.000325 0.000145 0.000118 0.001350 0.000253 0.000166 0.000070 0.001223 0.000287 0.000157 0.000105
Nucleus 0.074802 0.055380 0.324397 0.136591 0.103801 0.044376 0.217688 0.106061 0.099630 0.049557 0.263715 0.128470
Peroxisomes 0.005726 0.011165 0.000910 0.002445 0.006764 0.018674 0.000806 0.004700 0.006615 0.015139 0.000851 0.003045
Vacuole 0.075281 0.103776 0.091387 0.256461 0.064980 0.085154 0.126296 0.313741 0.066461 0.093921 0.111239 0.271697
Vacuole Periphery 0.000585 0.001226 0.000111 0.003140 0.000775 0.001618 0.000365 0.001826 0.000748 0.001433 0.000255 0.002791

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.47 -4.34 -9.92 -6.65 -8.67 -4.39 1.52 -4.71 -3.87 -4.91 -5.06 0.45 -9.32 -7.15 -9.49
Bud Neck 0.01 6.78 5.73 11.19 -7.24 -9.52 12.68 10.73 16.31 -1.42 -8.65 14.78 11.61 19.27 -6.44
Bud Site -8.20 -6.40 -13.94 -9.41 -9.61 -10.30 -4.37 -8.57 -3.14 -7.06 -12.52 -7.02 -16.12 -8.01 -12.40
Cell Periphery 1.48 3.03 -3.58 -5.66 -7.34 -2.22 4.21 -5.40 -5.06 -5.81 -1.67 4.19 -8.32 -7.70 -9.53
Cytoplasm 5.16 6.07 11.01 8.07 8.12 7.01 -6.42 12.55 6.18 16.98 6.74 -1.50 15.51 8.57 18.44
Cytoplasmic Foci -3.70 13.74 14.73 29.04 3.34 -1.35 35.74 28.41 25.28 -3.85 -1.56 38.22 37.70 40.15 0.58
Eisosomes 1.17 7.29 2.30 1.42 -8.04 1.00 12.57 -0.91 -1.40 -5.68 1.71 14.13 2.08 0.69 -9.65
Endoplasmic Reticulum 0.25 -10.56 -6.30 -6.73 4.09 3.98 2.47 -5.48 -7.31 -6.71 3.18 -4.94 -7.17 -10.61 -3.66
Endosome -3.87 6.20 5.36 11.83 -2.22 -6.56 13.04 8.01 12.05 -1.81 -7.34 14.69 11.82 17.56 -2.70
Golgi -3.74 5.24 2.89 7.97 -2.56 -5.78 11.91 5.59 8.85 -1.82 -5.81 13.91 8.15 11.92 -2.77
Lipid Particles 2.52 6.71 6.30 9.00 -1.48 6.46 15.49 13.37 6.89 -8.88 7.79 16.32 14.73 10.69 -4.98
Mitochondria 0.22 1.26 0.91 2.42 -2.76 -3.47 4.21 3.26 5.00 -0.70 -2.77 4.21 2.88 5.36 -2.62
Mitotic Spindle -2.03 -1.63 -5.18 -3.15 -4.48 -2.28 -3.23 -2.20 -0.60 -1.07 -2.83 -3.07 -5.37 -3.09 -4.23
None 0.27 0.20 1.25 1.41 5.28 4.94 4.19 4.77 -0.85 3.11 4.62 4.21 4.93 0.96 5.99
Nuclear Periphery 3.33 -14.27 -2.53 -3.17 0.84 7.17 -1.69 -0.78 -1.93 -0.40 7.14 -3.43 -1.17 -3.72 0.21
Nuclear Periphery Foci -1.14 -13.68 -7.76 -7.50 4.35 6.93 0.14 -5.10 -6.62 -5.13 6.06 -7.81 -7.07 -10.25 -2.00
Nucleolus 1.64 4.10 4.46 5.82 1.91 5.47 5.75 6.40 6.86 3.67 5.44 6.10 6.51 7.93 3.23
Nucleus 3.24 -31.18 -8.46 -16.29 27.11 15.58 -21.97 0.13 -10.92 18.03 15.64 -36.50 -5.86 -20.54 29.07
Peroxisomes -3.33 4.13 3.04 7.39 -2.23 -8.89 11.27 1.73 7.07 -1.77 -8.86 12.69 6.09 12.33 -2.85
Vacuole -4.16 -4.89 -26.76 -26.52 -26.41 -4.85 -19.51 -25.09 -22.54 -16.82 -8.30 -19.72 -41.74 -35.61 -29.23
Vacuole Periphery -3.29 3.43 -2.29 -1.42 -2.99 -4.02 3.33 -0.93 0.32 -1.59 -5.03 5.82 -2.29 -1.05 -3.21
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
Localization
Cell Percentages cytoplasm (32%), ER (5%), mixed (53%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ppz2

Ppz2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ppz2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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