Standard name
Human Ortholog
Description Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.07 0.05 0 0.05 0.05 0.06 0 0.06 0 0.08 0.16 0.14 0.06 0.05 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.14 0 0.05 0 0.06 0.22 0.34 0.19 0.43 0.32 0.46 0.25 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.93 0.93 0.95 0.91 0.93 0.89 0.84 0.86 0.8 0.85 0.8 0.87 0.91 0.81 0.83 0.86 0.87 0.87 0.86 0.85 0.83 0.78 0.66 0.6
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.21 0.1 0 0 0 0 0.07 0 0.08 0.08 0.09 0.09 0 0 0 0 0 0.06 0.05 0.06 0.08 0.11 0.17 0.15
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0.05 0.09 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 1 1 3 1 2 2 1 0 0 0 0 0 0 0 0 0 1 1 6
Bud Neck 0 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 3 2 4 5 9 5 6 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0
Cytoplasm 3 5 4 21 15 18 26 24 23 13 22 5 30 57 51 16 13 16 0 1 0 0 2 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 4 3 1 0 0 0 0 1 3
Endosome 0 0 0 2 0 0 1 0 0 0 0 0 2 0 2 1 2 1 3 0 1 1 6 10
Golgi 0 1 2 0 0 0 0 0 0 0 0 0 1 2 0 2 3 0 1 2 1 0 1 1
Mitochondria 21 4 10 11 18 92 177 99 159 135 177 81 2 1 0 10 8 10 1 1 2 3 4 11
Nucleus 143 142 209 271 275 381 441 451 294 358 308 276 340 282 298 232 217 248 134 140 196 186 218 281
Nuclear Periphery 2 0 0 0 1 2 1 2 3 3 1 2 1 1 0 3 4 0 0 0 0 0 0 4
Nucleolus 32 15 4 5 1 4 36 22 31 34 35 28 8 9 11 1 3 16 7 9 19 25 55 70
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0
SpindlePole 0 0 10 4 3 2 0 9 3 5 4 4 6 4 5 4 2 0 0 1 1 5 6 13
Vac/Vac Membrane 0 0 1 4 4 1 2 0 2 3 4 6 1 4 3 16 8 12 4 6 9 11 28 53
Unique Cell Count 153 152 219 297 297 427 528 522 368 422 383 319 374 350 358 269 249 284 156 165 237 239 330 466
Labelled Cell Count 201 167 240 318 317 504 688 616 522 562 558 409 391 361 373 289 264 306 156 165 237 239 330 466


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 7.6 6.2 6.0 5.9 4.9 4.7 5.4 4.6 4.9 4.6 5.1 6.7 7.0 6.9 9.5 9.3 8.6 6.7 7.0 7.5
Std Deviation (1e-4) 0.7 1.3 1.4 1.5 1.4 1.3 1.4 1.4 1.4 1.3 1.4 1.2 1.5 1.8 1.4 2.0 2.2 2.0 1.3 1.4 1.5
Intensity Change (Log2) – – – -0.04 -0.07 -0.33 -0.39 -0.21 -0.43 -0.34 -0.44 -0.29 0.11 0.19 0.16 0.62 0.59 0.48 0.12 0.18 0.29

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.7 1.9 1.6 2.0 1.8 2.5 0.9 2.3 0 3.1 5.4 4.9 2.3 2.0 2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.5 0.7 5.6 0 5.0 0 0 0 6.3 0 0 0 -0.5 -0.8 -0.6
Nucleus -1.8 -1.3 -2.7 -4.4 -3.6 -5.2 -4.0 -5.1 -3.4 -2.0 -5.0 -4.4 -3.4 -3.1 -3.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1.6 0 0 0 3.3 0 0.6 0.9 0 0 2.2
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole -2.2 -2.5 0 0 -2.2 0 0 0 -2.4 -2.1 -2.6 -2.3 -2.0 -2.6 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 3.3 0 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9297 1.3655 1.3452 1.156 0.7055 0.9969 1.3043 1.5951 1.1674 1.17 1.494 1.4295 2.1565 1.9607 1.6836 1.7749 1.7315 1.9565
Actin 0.0259 0.0004 0.0266 0.0017 0.0392 0.0003 0.0026 0.0002 0 0.0023 0.0001 0.0012 0.0381 0 0.0175 0 0.002 0.0048
Bud 0.0006 0 0.0005 0.0001 0.0002 0 0.0011 0.0004 0 0.0002 0.0001 0.0001 0.001 0 0.0004 0 0.0002 0.0004
Bud Neck 0.0038 0.0001 0.0028 0.0001 0.002 0.0004 0.0018 0.0003 0.0001 0.0008 0.0005 0.0007 0.0036 0.0001 0.0008 0 0.0004 0.0008
Bud Periphery 0.001 0 0.0008 0.0001 0.0004 0.0001 0.0026 0.0005 0 0.0004 0.0002 0.0003 0.0014 0 0.0007 0 0.0005 0.0009
Bud Site 0.0093 0.0002 0.0078 0.0003 0.0004 0 0.0088 0.0026 0 0.0007 0.0001 0.0001 0.0042 0.0001 0.0021 0 0.0002 0.0004
Cell Periphery 0.0003 0 0.0002 0 0.0001 0 0.0005 0.0001 0 0.0002 0 0.0002 0.0004 0 0.0002 0 0 0.0001
Cytoplasm 0.0178 0.0001 0.0016 0.0015 0.0038 0.0001 0.0089 0.0003 0.0014 0.0051 0.0002 0.002 0.004 0.0001 0.0007 0 0.0002 0.0005
Cytoplasmic Foci 0.016 0.001 0.0059 0.0034 0.0009 0.0001 0.0084 0.0006 0.0005 0.0064 0 0.0012 0.0095 0 0.0032 0 0.0004 0.0006
Eisosomes 0.0006 0 0.0002 0 0.0008 0 0.0001 0 0 0.0001 0 0 0.0004 0 0.0002 0 0 0.0001
Endoplasmic Reticulum 0.0057 0 0.0018 0.0011 0.005 0.0005 0.0009 0 0.0001 0.0021 0.0001 0.0019 0.0028 0 0.001 0 0.0012 0.0008
Endosome 0.022 0.0005 0.0199 0.0223 0.0158 0.0025 0.0083 0.0007 0.0056 0.0381 0 0.0112 0.0126 0 0.0084 0 0.0135 0.0044
Golgi 0.0097 0.001 0.0082 0.0019 0.0041 0.0004 0.0024 0.0003 0.0011 0.0105 0 0.0022 0.004 0 0.004 0 0.0022 0.0009
Lipid Particles 0.027 0.001 0.0108 0.0041 0.0051 0.0013 0.0076 0.0001 0.0034 0.0243 0 0.0043 0.0074 0 0.0068 0 0.0024 0.0009
Mitochondria 0.0099 0.0009 0.0093 0.0007 0.0029 0.0004 0.0197 0.0008 0.0005 0.0343 0.0006 0.0044 0.0132 0.0001 0.0031 0.0001 0.0058 0.0049
None 0.0169 0 0.0016 0.0024 0.007 0.0001 0.0011 0 0.0097 0.0023 0.0001 0.0015 0.0068 0 0.0007 0 0.0006 0.0006
Nuclear Periphery 0.0359 0.0008 0.0099 0.0063 0.0633 0.0084 0.0059 0.0006 0.0003 0.0043 0.0045 0.0092 0.0169 0.001 0.0099 0.0009 0.0199 0.0099
Nucleolus 0.0262 0.0152 0.0147 0.0068 0.0535 0.041 0.0229 0.0208 0.0138 0.0103 0.0797 0.0615 0.021 0.0187 0.0111 0.0144 0.0516 0.043
Nucleus 0.7302 0.9655 0.8567 0.939 0.7737 0.9415 0.869 0.9693 0.9625 0.8416 0.8858 0.8748 0.8211 0.9774 0.9138 0.9842 0.8921 0.9175
Peroxisomes 0.0164 0.0019 0.0055 0.0008 0.001 0.0001 0.002 0.0006 0.0001 0.0086 0 0.0004 0.0063 0 0.0025 0 0.0004 0.0004
Punctate Nuclear 0.0195 0.0112 0.0118 0.0064 0.0149 0.0019 0.0187 0.0013 0.0003 0.0008 0.0276 0.0208 0.0194 0.0025 0.0104 0.0003 0.002 0.0058
Vacuole 0.0033 0.0001 0.0022 0.0006 0.0028 0.0003 0.0046 0.0003 0.0005 0.0043 0.0002 0.0013 0.0035 0 0.0015 0 0.0014 0.0012
Vacuole Periphery 0.0021 0 0.0013 0.0005 0.0032 0.0005 0.002 0.0001 0.0002 0.0023 0.0001 0.0008 0.0023 0 0.0011 0 0.0031 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.9935 8.1687 14.3962 16.7271 6.6643 12.5577 13.9378 19.8593 23.4608 15.3033
Translational Efficiency 2.3317 4.0557 2.4659 2.2556 3.9756 2.1685 2.2002 1.5088 1.4549 1.6949

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
69 353 161 1138 2031 2158 1996 1293 2100 2511 2157 2431

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 842.28 874.27 1044.73 1017.76 774.02 850.85 962.94 1024.39 776.26 854.14 969.04 1021.29
Standard Deviation 108.19 136.41 127.61 159.14 98.08 112.61 142.34 175.10 99.18 116.53 142.92 167.85
Intensity Change Log 2 — 0.053779 0.310758 0.273026 — 0.136534 0.315075 0.404322 — 0.094002 0.312827 0.337394

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000493 0.000854 0.001399 0.002125 0.000220 0.000466 0.000699 0.001050 0.000229 0.000521 0.000751 0.001553
Bud Neck 0.004722 0.013332 0.009246 0.033087 0.006803 0.014161 0.015603 0.026214 0.006735 0.014045 0.015128 0.029432
Bud Site 0.000331 0.006507 0.001420 0.006720 0.000520 0.002100 0.001085 0.005688 0.000513 0.002720 0.001110 0.006171
Cell Periphery 0.000038 0.000097 0.000072 0.000126 0.000053 0.000054 0.000080 0.000154 0.000052 0.000060 0.000080 0.000141
Cytoplasm 0.000298 0.002613 0.001650 0.001938 0.001376 0.001835 0.001927 0.006476 0.001341 0.001944 0.001906 0.004351
Cytoplasmic Foci 0.000062 0.000458 0.000107 0.001044 0.000270 0.000821 0.000199 0.002732 0.000264 0.000770 0.000192 0.001942
Eisosomes 0.000027 0.000030 0.000055 0.000032 0.000018 0.000028 0.000035 0.000036 0.000019 0.000028 0.000037 0.000035
Endoplasmic Reticulum 0.003415 0.004309 0.004658 0.003707 0.002070 0.003388 0.002719 0.003342 0.002114 0.003518 0.002864 0.003513
Endosome 0.000126 0.000920 0.000182 0.002186 0.000236 0.001028 0.000137 0.004158 0.000233 0.001013 0.000141 0.003235
Golgi 0.000067 0.000823 0.000149 0.001768 0.000107 0.000589 0.000088 0.002384 0.000106 0.000622 0.000092 0.002096
Lipid Particles 0.000147 0.001160 0.000191 0.000147 0.000113 0.000340 0.000076 0.000578 0.000114 0.000455 0.000084 0.000377
Mitochondria 0.000670 0.001394 0.001141 0.004875 0.000580 0.002752 0.000952 0.002826 0.000583 0.002561 0.000966 0.003785
Mitotic Spindle 0.000019 0.001491 0.003987 0.025320 0.001849 0.007078 0.001692 0.019794 0.001789 0.006293 0.001863 0.022381
None 0.001892 0.004358 0.003101 0.003027 0.002291 0.002173 0.006947 0.009422 0.002278 0.002480 0.006660 0.006428
Nuclear Periphery 0.000217 0.000174 0.000215 0.002739 0.000287 0.000883 0.000228 0.001497 0.000285 0.000783 0.000227 0.002078
Nuclear Periphery Foci 0.000073 0.001085 0.000164 0.001312 0.000200 0.000733 0.000110 0.001988 0.000195 0.000782 0.000114 0.001671
Nucleolus 0.029059 0.043789 0.033933 0.010584 0.038559 0.042822 0.027059 0.015778 0.038247 0.042958 0.027573 0.013347
Nucleus 0.957504 0.913743 0.935926 0.891818 0.943760 0.915205 0.939585 0.886292 0.944212 0.915000 0.939312 0.888879
Peroxisomes 0.000546 0.000704 0.000985 0.000318 0.000230 0.001017 0.000254 0.000657 0.000241 0.000973 0.000308 0.000498
Vacuole 0.000206 0.001554 0.001261 0.004861 0.000277 0.001637 0.000433 0.006310 0.000275 0.001626 0.000495 0.005632
Vacuole Periphery 0.000088 0.000606 0.000161 0.002264 0.000181 0.000888 0.000092 0.002625 0.000178 0.000849 0.000097 0.002456

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.47 -7.86 -2.68 -1.91 -0.37 -6.13 -19.92 -19.25 -12.33 -9.33 -7.88 -21.66 -5.75 -4.37 -3.13
Bud Neck -3.70 -3.47 -11.74 -7.14 -10.12 -7.74 -12.91 -14.72 -9.60 -6.89 -8.17 -13.02 -18.51 -12.43 -9.65
Bud Site -2.01 -6.81 -5.94 0.25 -4.10 -4.91 -7.17 -6.35 -3.65 -5.30 -4.46 -7.90 -8.48 -3.33 -7.06
Cell Periphery -2.51 -1.90 -4.29 -0.25 -1.54 -0.31 -2.19 -5.34 -5.66 -3.98 -0.94 -2.31 -5.49 -5.29 -3.94
Cytoplasm -2.18 -1.32 -4.15 0.01 -0.09 -1.16 -1.10 -4.20 -3.38 -3.89 -1.46 -1.29 -4.21 -2.87 -3.68
Cytoplasmic Foci -1.68 -1.04 -1.57 -0.35 -1.37 -1.77 0.74 -2.16 -0.94 -2.47 -1.80 0.76 -2.14 -0.51 -2.64
Eisosomes -0.65 -5.24 -1.81 -2.22 5.62 -7.00 -16.06 -14.34 -6.81 -2.89 -7.60 -17.40 -15.83 -6.56 -0.39
Endoplasmic Reticulum -1.62 -2.60 -1.14 0.92 2.35 -6.32 -6.24 -10.28 -2.92 -6.57 -7.40 -7.25 -11.66 -2.55 -6.45
Endosome -2.02 -1.92 -3.24 -0.74 -2.98 -3.07 1.70 -3.00 -1.63 -3.14 -3.39 1.58 -3.97 -1.66 -4.20
Golgi -1.86 -5.22 -2.04 -0.39 -1.79 -1.92 0.11 -2.29 -1.18 -2.30 -2.29 -0.09 -2.99 -1.28 -3.00
Lipid Particles -0.97 -1.11 -0.05 0.96 1.32 -2.29 1.22 -1.77 -0.13 -2.01 -2.07 0.96 -1.86 1.05 -2.22
Mitochondria -2.44 -4.77 -8.36 -5.58 -7.00 -5.17 -7.49 -9.50 -0.14 -7.42 -5.45 -8.05 -12.30 -2.24 -10.22
Mitotic Spindle -2.07 -1.43 -6.39 -5.39 -3.88 -3.52 -0.46 -6.23 -4.26 -6.18 -3.46 -0.68 -8.23 -5.86 -8.13
None -1.35 -1.17 -2.05 0.65 0.12 0.12 -4.27 -3.92 -3.91 -0.52 -0.47 -4.33 -3.99 -3.39 0.81
Nuclear Periphery -0.22 -0.62 -5.39 -5.56 -5.42 -3.88 0.15 -3.96 -1.76 -4.02 -3.80 0.09 -6.61 -3.91 -6.73
Nuclear Periphery Foci -1.58 -2.21 -3.74 0.67 -3.11 -1.96 1.13 -2.17 -0.87 -2.33 -2.42 1.02 -3.20 -0.55 -3.47
Nucleolus -2.28 -1.06 3.10 7.66 5.28 -2.01 4.16 10.39 11.80 6.04 -2.30 3.94 13.47 15.66 8.97
Nucleus 4.65 3.28 7.60 1.52 3.57 7.36 3.55 9.47 3.88 7.59 8.03 3.93 11.48 4.09 8.93
Peroxisomes -0.95 -2.81 1.52 3.77 5.66 -2.99 -0.66 -3.56 1.91 -3.65 -3.16 -1.69 -3.15 2.44 -2.51
Vacuole -2.58 -4.89 -5.83 -2.84 -3.51 -4.76 -1.40 -5.45 -3.75 -4.80 -5.23 -1.75 -7.63 -4.81 -6.26
Vacuole Periphery -1.97 -5.36 -3.13 -1.61 -2.91 -3.68 1.72 -2.45 -0.96 -2.63 -3.92 1.58 -3.67 -1.47 -3.94
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Tfb3

Tfb3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tfb3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available