Standard name
Human Ortholog
Description Subunit of the COMPASS (Set1C) complex; COMPASS methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0.08 0.06 – 0.05 0 0 0.05 0.05 0.11 0.14 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.09 0 0 0 0.28 0 – 0.18 0.22 0.28 0.23 0 0 0 0 0.06 0 0 0 0 0 0 0
Nucleus 0.84 0.91 0.91 0.93 0.89 0.75 0.85 – 0.75 0.8 0.8 0.72 0.94 0.86 0.8 0.87 0.87 0.88 0.65 0.83 0.78 0.74 0.74 0.61
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.15 0.1 0.06 0.06 0 0.07 0.07 – 0.15 0.15 0.19 0.15 0.08 0.06 0 0.08 0.06 0.08 0.16 0.09 0.11 0.15 0.15 0.19
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 1
Bud 0 0 0 0 0 2 2 – 2 3 1 2 0 0 0 0 0 1 6 1 1 0 3 4
Bud Neck 0 0 1 0 0 0 0 – 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 1 0 0 0 4 2 – 7 9 10 9 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 12 6 6 6 19 29 27 – 15 13 8 17 11 39 48 10 6 5 1 0 1 0 0 1
Endoplasmic Reticulum 0 0 0 1 0 0 0 – 1 0 0 0 0 0 2 5 2 1 0 0 0 0 0 0
Endosome 7 1 0 2 14 2 11 – 2 2 0 2 0 1 7 2 2 3 9 1 0 1 1 5
Golgi 2 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 1 0 4 1 0 0 0 0
Mitochondria 13 22 1 5 4 97 11 – 53 86 62 73 2 0 0 11 10 6 4 1 0 0 0 3
Nucleus 241 212 133 199 335 263 389 – 217 314 180 227 211 297 267 219 153 150 211 209 126 61 156 139
Nuclear Periphery 0 0 2 0 6 3 0 – 4 4 0 3 0 3 1 1 2 2 0 0 0 0 0 0
Nucleolus 44 23 9 12 9 25 34 – 44 59 43 49 19 19 13 21 11 14 52 22 18 12 31 43
Peroxisomes 1 0 0 0 1 0 0 – 1 0 0 0 0 1 4 1 0 0 0 0 0 0 0 1
SpindlePole 10 0 3 9 4 5 14 – 12 8 2 7 2 5 3 0 6 1 14 2 5 0 5 5
Vac/Vac Membrane 7 1 2 2 10 8 7 – 8 2 2 7 0 2 4 5 6 7 12 8 5 4 9 15
Unique Cell Count 288 233 146 215 378 351 460 291 392 224 317 224 344 334 253 175 170 325 252 162 83 211 227
Labelled Cell Count 337 266 157 236 402 438 497 366 500 309 398 245 367 349 276 199 190 325 252 162 83 211 227


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.9 6.5 6.0 7.3 5.0 6.1 – 5.3 5.4 5.1 5.5 6.9 6.9 6.8 8.7 8.8 8.7 6.0 6.3 6.4
Std Deviation (1e-4) 1.4 1.2 1.0 1.4 2.3 1.5 1.7 – 1.9 1.3 1.6 1.4 1.7 1.8 1.9 1.9 2.2 2.1 1.5 1.6 1.5
Intensity Change (Log2) – – – -0.1 0.17 -0.38 -0.1 – -0.28 -0.25 -0.33 -0.24 0.1 0.09 0.08 0.43 0.45 0.43 -0.12 -0.03 -0.03

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.4 1.6 0.8 – 0.5 -0.4 -0.3 0.6 0.4 2.5 3.3 -0.1 -0.3 -0.6
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 6.9 0 – 5.3 6.0 6.8 6.1 0 0 0 0 2.5 0
Nucleus 0.5 -0.8 -4.1 -2.0 – -4.1 -3.0 -2.8 -4.7 1.1 -1.5 -3.0 -1.4 -1.0 -0.8
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus -0.2 -2.1 0.4 0.5 – 2.7 2.8 3.5 2.8 0.8 -0.3 -1.1 0.8 0 0.7
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 1.1 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.8909 1.2511 1.1887 0.9745 0.4957 1.2922 1.9383 2.6627 2.3498 1.99 2.3028 2.431 3.6623 4.4249 3.6726 3.8307 3.7912 3.6299
Actin 0.0043 0 0.0002 0.0001 0.0001 0.0001 0.0006 0 0 0 0 0.0007 0.002 0 0.014 0.001 0.0158 0.0004
Bud 0.0001 0 0 0 0 0 0.0001 0 0 0 0 0 0.0001 0 0.0001 0 0.0003 0.0001
Bud Neck 0.0006 0.0001 0.0001 0.0002 0.0009 0.0006 0.0008 0 0.0001 0.0001 0.0008 0.0009 0.0003 0.0001 0.0003 0.0002 0.0016 0.0018
Bud Periphery 0.0002 0 0 0 0.0001 0 0.0003 0 0 0 0.0001 0.0001 0.0001 0 0.0001 0 0.0008 0.0003
Bud Site 0.0004 0 0 0 0.0002 0 0.0013 0 0.0001 0 0.0001 0.0001 0.0003 0.0001 0.0005 0.0001 0.0008 0.0004
Cell Periphery 0.0001 0 0 0 0 0 0.0002 0 0 0 0 0 0.0001 0 0 0 0.0001 0.0001
Cytoplasm 0.0034 0.0002 0.0001 0.0025 0.0001 0 0.0008 0.0001 0.0001 0.0001 0.0002 0 0.0079 0.0003 0.0025 0.0003 0.002 0.0003
Cytoplasmic Foci 0.0037 0 0.0007 0.0011 0 0 0.0013 0 0 0 0 0.0001 0.0169 0 0.0022 0.0264 0.0022 0.0002
Eisosomes 0.0001 0 0 0 0 0 0.0001 0 0 0 0 0 0.0001 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.0028 0 0 0.0003 0 0.0001 0.0003 0 0 0 0 0 0.0027 0 0.0001 0 0.002 0.0001
Endosome 0.0094 0 0.0001 0.0011 0.0001 0.0004 0.0009 0 0 0 0 0.0002 0.0171 0.0001 0.0006 0.0033 0.0149 0.0006
Golgi 0.0014 0 0.0001 0.0001 0 0.0001 0.0002 0 0 0 0 0.0002 0.0012 0 0.0016 0.0036 0.0022 0.0001
Lipid Particles 0.0039 0 0.0015 0.0005 0 0.0002 0.0014 0 0 0 0 0.0011 0.0043 0 0.0021 0.0298 0.0043 0.0002
Mitochondria 0.0009 0.0001 0.0001 0.0001 0.0003 0.0002 0.0051 0.0002 0.0001 0.0001 0.0002 0.0011 0.0012 0.0002 0.0007 0.0005 0.0017 0.0107
None 0.0031 0 0.0001 0.0051 0.0001 0 0.0019 0 0 0.0001 0 0 0.0253 0.0001 0.0022 0.0004 0.0023 0.0002
Nuclear Periphery 0.0138 0.002 0.0013 0.0037 0.0026 0.0049 0.001 0.0034 0.0012 0.0006 0.002 0.0006 0.0213 0.0019 0.0012 0.0006 0.0364 0.0014
Nucleolus 0.0339 0.0212 0.0198 0.0181 0.1202 0.0733 0.0351 0.0234 0.0254 0.0181 0.0978 0.0712 0.0259 0.026 0.0327 0.0098 0.1224 0.0782
Nucleus 0.8943 0.9746 0.9661 0.9443 0.8618 0.917 0.9381 0.9705 0.9675 0.9789 0.8399 0.9209 0.8546 0.9646 0.9286 0.905 0.729 0.8914
Peroxisomes 0.0057 0 0.0069 0 0 0 0.001 0 0 0 0 0.0005 0.0011 0 0.0051 0.0175 0.0017 0.0002
Punctate Nuclear 0.0162 0.0015 0.0028 0.0225 0.0133 0.0025 0.0084 0.0022 0.0053 0.0019 0.0586 0.002 0.0155 0.0063 0.0054 0.0013 0.057 0.012
Vacuole 0.001 0.0001 0 0.0002 0.0001 0.0001 0.0005 0 0 0 0.0001 0.0001 0.0012 0.0001 0.0001 0.0001 0.0014 0.0005
Vacuole Periphery 0.0007 0 0 0.0001 0.0001 0.0003 0.0004 0.0001 0 0 0 0.0001 0.0008 0 0 0 0.0011 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.0325 22.4176 16.6349 23.7502 12.1927 10.4431 22.6665 23.5849 18.3003 28.5535
Translational Efficiency 1.6896 1.6743 1.6044 1.1677 3.3178 3.6532 1.6109 1.3693 1.5647 1.238

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1910 1171 2686 72 1554 2106 607 779 3464 3277 3293 851

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.57 814.27 956.34 1039.49 762.22 891.24 996.89 949.51 757.45 863.74 963.81 957.12
Standard Deviation 102.93 163.39 124.89 177.51 105.95 113.56 130.24 147.16 104.38 138.52 126.87 152.04
Intensity Change Log 2 — 0.111766 0.343782 0.464062 — 0.225607 0.387227 0.316976 — 0.170133 0.365792 0.391973

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000351 0.001333 0.000627 0.002802 0.000446 0.000476 0.001270 0.001546 0.000393 0.000782 0.000746 0.001652
Bud Neck 0.005121 0.013778 0.032934 0.017710 0.005809 0.012889 0.010966 0.033364 0.005430 0.013207 0.028885 0.032040
Bud Site 0.000760 0.002774 0.002492 0.012842 0.000844 0.001912 0.002309 0.024178 0.000797 0.002220 0.002458 0.023219
Cell Periphery 0.000142 0.000225 0.000065 0.000118 0.000101 0.000091 0.000084 0.000279 0.000123 0.000139 0.000069 0.000265
Cytoplasm 0.007934 0.017445 0.002421 0.006457 0.006638 0.005340 0.003743 0.043312 0.007353 0.009665 0.002665 0.040194
Cytoplasmic Foci 0.002031 0.004132 0.000199 0.004507 0.001112 0.001623 0.000199 0.006632 0.001619 0.002519 0.000199 0.006452
Eisosomes 0.000022 0.000044 0.000027 0.000040 0.000027 0.000030 0.000047 0.000046 0.000025 0.000035 0.000031 0.000046
Endoplasmic Reticulum 0.002433 0.004975 0.002436 0.004927 0.002330 0.003055 0.005355 0.006405 0.002387 0.003741 0.002974 0.006280
Endosome 0.000373 0.001657 0.000253 0.004106 0.000384 0.000970 0.000519 0.014166 0.000378 0.001215 0.000302 0.013315
Golgi 0.000243 0.000940 0.000157 0.000841 0.000182 0.000565 0.000351 0.007919 0.000216 0.000699 0.000193 0.007320
Lipid Particles 0.000426 0.001644 0.000066 0.000559 0.000703 0.000883 0.000304 0.000586 0.000550 0.001155 0.000110 0.000584
Mitochondria 0.001181 0.003833 0.001784 0.002041 0.001721 0.004429 0.001289 0.011049 0.001423 0.004216 0.001693 0.010287
Mitotic Spindle 0.000860 0.005918 0.004017 0.139870 0.002377 0.009730 0.007374 0.053775 0.001541 0.008368 0.004636 0.061059
None 0.015226 0.023877 0.002571 0.005339 0.007822 0.004735 0.006826 0.011755 0.011904 0.011576 0.003355 0.011212
Nuclear Periphery 0.000482 0.000756 0.000578 0.000967 0.000586 0.001001 0.000674 0.002329 0.000529 0.000914 0.000595 0.002214
Nuclear Periphery Foci 0.001362 0.001790 0.000159 0.000287 0.000825 0.000695 0.000522 0.001319 0.001121 0.001086 0.000226 0.001232
Nucleolus 0.072525 0.078525 0.043987 0.015202 0.056376 0.062663 0.047222 0.014744 0.065280 0.068331 0.044583 0.014783
Nucleus 0.887421 0.832531 0.903850 0.772971 0.909986 0.885208 0.906602 0.729675 0.897544 0.866384 0.904358 0.733338
Peroxisomes 0.000428 0.001999 0.000270 0.002676 0.001026 0.000951 0.000781 0.001131 0.000696 0.001326 0.000365 0.001261
Vacuole 0.000414 0.001291 0.000861 0.005431 0.000432 0.001759 0.002113 0.027868 0.000422 0.001592 0.001092 0.025970
Vacuole Periphery 0.000265 0.000532 0.000245 0.000309 0.000271 0.000996 0.001450 0.007922 0.000268 0.000830 0.000467 0.007278

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.26 -14.48 -4.22 -2.30 -3.53 -0.44 -9.85 -6.93 -7.17 -2.22 -4.19 -10.83 -8.38 -5.92 -6.01
Bud Neck -8.82 -28.47 -4.10 -1.92 3.34 -6.64 -6.22 -13.18 -9.84 -8.41 -10.77 -28.28 -14.18 -10.06 -0.98
Bud Site -5.69 -5.95 -2.53 -2.05 -2.08 -3.44 -3.10 -6.33 -5.89 -5.47 -6.41 -6.59 -6.68 -6.03 -5.79
Cell Periphery -2.56 4.36 -0.60 1.78 -3.98 0.50 1.26 -5.31 -5.53 -6.69 -0.96 4.95 -4.36 -3.44 -8.32
Cytoplasm -4.22 6.43 -0.45 2.59 -2.77 0.66 2.61 -8.02 -8.35 -9.07 -2.38 7.11 -7.94 -6.94 -9.65
Cytoplasmic Foci -1.81 3.37 0.48 1.88 -1.56 -1.56 4.19 -2.74 -1.27 -5.14 -1.77 4.48 -1.52 0.06 -5.29
Eisosomes -8.46 -5.62 -5.06 -2.59 -4.40 -1.13 -8.65 -9.95 -9.33 -3.56 -6.68 -7.02 -12.28 -8.66 -9.99
Endoplasmic Reticulum -9.62 -2.05 -5.14 -3.36 -4.96 -3.41 -10.97 -11.71 -10.29 -5.68 -8.36 -7.35 -12.59 -9.97 -11.04
Endosome -3.24 2.18 -2.07 -0.70 -2.18 -3.22 -0.69 -4.59 -4.06 -4.50 -4.58 1.89 -4.76 -3.90 -4.84
Golgi -3.63 0.81 -1.26 1.87 -1.65 -1.98 -1.38 -3.03 -2.55 -2.82 -3.39 -0.08 -3.01 -2.39 -3.01
Lipid Particles -2.47 5.21 -2.13 1.21 -3.81 -1.21 2.96 -0.04 1.36 -4.53 -3.00 6.48 -1.93 2.16 -9.62
Mitochondria -3.46 -3.81 -2.59 0.67 -1.64 -3.27 0.39 -3.73 -1.47 -4.44 -5.15 -1.39 -4.48 -1.62 -4.21
Mitotic Spindle -3.57 -4.75 -2.89 -2.68 -2.72 -3.71 -2.65 -7.75 -6.16 -5.24 -5.31 -4.70 -8.46 -6.99 -7.43
None -2.86 10.39 7.67 7.19 -1.72 3.42 1.62 -0.21 -2.77 -1.52 0.43 11.30 3.46 2.66 -4.44
Nuclear Periphery -2.83 -3.13 -3.97 -3.48 -3.65 -2.45 -0.88 -11.15 -8.76 -9.58 -3.61 -2.48 -12.46 -10.12 -11.81
Nuclear Periphery Foci -0.77 2.89 0.22 0.97 -2.31 1.22 1.36 -0.73 -2.90 -3.07 0.73 3.54 -0.60 -1.64 -5.02
Nucleolus -1.23 6.45 13.01 13.14 9.17 -1.74 0.34 14.47 17.04 9.10 -0.86 5.17 21.72 22.27 16.07
Nucleus 7.89 -0.94 2.62 1.03 2.75 4.57 2.58 13.74 11.28 10.90 7.35 1.69 13.12 9.72 12.52
Peroxisomes -4.89 1.89 -1.52 0.79 -1.71 -0.17 0.46 0.89 1.84 1.29 -2.88 1.58 -0.09 3.23 -2.31
Vacuole -4.54 -2.69 -2.89 -2.80 -2.85 -3.96 -4.15 -9.77 -9.41 -9.18 -5.40 -4.59 -10.19 -9.85 -9.98
Vacuole Periphery -3.11 0.36 -0.42 3.48 -1.08 -2.96 -0.90 -3.89 -2.72 -1.89 -3.49 -0.68 -3.90 -2.95 -3.64
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the COMPASS (Set1C) complex; COMPASS methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30
Localization
Cell Percentages nucleus (97%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Sdc1

Sdc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sdc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available