Standard name
Human Ortholog
Description Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; involved in localization of actin and chitin; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.06 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0.05 0.06 0.08 – 0.11 0.1 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.07 0.06 0 0 0 – 0 0 0 0 0 0 0.14 0.17 0.2 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0.26 0.13 0.25 0.15 0.17 0 0 0 – 0 0 0 0.33 0.3 0.39 0.37 0.32 0.37 0.31 0.28 0.27 0.21 0.18 0.15
Golgi 0.14 0.12 0 0 0 0 0 0 – 0 0 0 0.36 0.39 0.28 0.08 0.14 0.21 0.32 0.39 0.28 0.27 0.31 0.38
Mitochondria 0.66 0.8 0.56 0.75 0.69 0.93 0.92 0.89 – 0.92 0.94 0.92 0.2 0.15 0.08 0.1 0.09 0.05 0.05 0.08 0.05 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0.06 0 0.08 0 0 0 0.06 0.05 0 0 0 0 0 0 0
Peroxisomes 0.05 0.09 0.23 0.16 0.1 0.05 0.08 0.11 – 0.06 0.07 0.05 0.11 0.12 0.12 0.3 0.22 0.17 0.25 0.16 0.33 0.41 0.44 0.36
SpindlePole 0.12 0.05 0.22 0.09 0.12 0 0.08 0.11 – 0.08 0.06 0.07 0.16 0.17 0.21 0.28 0.21 0.17 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0.1 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 25 5 2 1 1 0 5 – 0 0 0 27 19 17 2 5 0 8 11 9 5 6 11
Bud 5 16 11 5 6 14 19 32 – 47 23 17 8 9 11 7 8 1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 1 1 2 2 0 0 0 0 0 0 0 0
Bud Site 0 2 0 1 0 3 5 13 – 11 8 10 0 1 0 0 1 0 – – – – – –
Cell Periphery 4 1 0 1 1 0 1 1 – 0 1 2 2 3 5 2 1 0 0 0 0 0 0 0
Cytoplasm 6 9 10 13 10 9 8 16 – 7 5 8 11 14 25 39 49 23 0 1 0 0 0 2
Endoplasmic Reticulum 5 8 2 0 1 0 0 1 – 0 0 0 5 8 2 2 7 6 0 0 0 1 1 1
Endosome 100 56 80 28 28 2 5 3 – 1 3 2 192 261 337 99 90 43 137 131 96 77 67 62
Golgi 53 52 13 3 3 1 0 0 – 0 1 0 207 336 244 22 40 24 142 182 102 100 117 161
Mitochondria 252 341 178 139 112 268 307 364 – 387 218 294 117 133 73 26 26 6 22 38 17 16 10 18
Nucleus 0 0 1 2 0 3 4 1 – 5 0 1 0 4 4 1 2 1 1 0 1 0 0 1
Nuclear Periphery 0 0 2 0 2 4 4 2 – 5 2 4 0 1 2 1 4 1 1 0 0 0 0 0
Nucleolus 11 6 5 1 3 7 14 8 – 25 7 25 4 11 18 16 13 0 0 0 0 0 0 1
Peroxisomes 21 37 72 29 16 15 26 44 – 27 16 16 64 102 103 81 64 20 111 76 118 150 168 151
SpindlePole 46 22 70 16 20 11 27 44 – 33 13 22 95 147 181 77 59 20 15 4 10 10 2 0
Vac/Vac Membrane 12 12 1 0 2 3 3 6 – 1 0 3 25 40 83 7 8 3 3 10 1 1 1 3
Unique Cell Count 383 426 318 186 162 287 334 408 420 233 320 577 859 866 271 285 116 446 465 362 367 380 421
Labelled Cell Count 521 587 450 240 205 341 423 540 549 297 404 758 1090 1107 384 377 148 446 465 362 367 380 421


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.7 6.5 6.0 5.4 5.2 4.2 4.1 4.2 – 3.7 3.9 3.9 7.7 7.8 8.0 6.4 7.3 8.0 7.6 7.8 8.3
Std Deviation (1e-4) 0.8 0.8 1.1 1.4 1.8 1.0 1.2 1.0 – 0.9 0.8 0.9 0.8 0.8 0.9 1.2 1.3 1.5 1.4 1.1 1.5
Intensity Change (Log2) – – – -0.14 -0.19 -0.5 -0.54 -0.49 – -0.68 -0.6 -0.62 0.37 0.39 0.43 0.11 0.29 0.43 0.36 0.38 0.48

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 2.4 0.7 0.4 0 0 0
Bud -0.5 0.1 0 0 0 – 0 0 0 -2.1 -2.8 -2.5 -0.6 -0.5 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 2.0 1.6 0 -0.6 0.6 – -1.3 -0.7 -0.5 -1.2 -1.6 -0.2 4.9 5.8 5.8
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome -2.7 -2.0 0 0 0 – 0 0 0 2.5 1.8 4.4 3.0 1.7 2.4
Golgi -1.5 -1.3 0 0 0 – 0 0 0 10.6 11.7 8.9 2.1 4.3 5.5
Mitochondria 4.2 2.8 0 0 0 – 0 0 0 -10.9 -14.0 -17.7 -11.8 -12.1 -9.5
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0.6 2.8 2.2 0
Peroxisomes -1.9 -3.4 0 0 0 – 0 0 0 -4.6 -4.6 -4.6 2.0 -0.1 -1.2
SpindlePole -3.9 -2.6 0 0 0 – 0 0 0 -2.0 -1.9 -0.4 1.8 -0.4 -1.1
Vacuole 0 0 0 0 0 – 0 0 0 3.4 3.6 5.5 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.8629 1.5767 1.2069 1.3996 1.7169 1.4453 1.3634 1.9582 1.5264 1.313 1.0629 1.7268 0.8527 1.3005 1.2073 0.9018 0.9344 1.1359
Actin 0.0041 0.0134 0.0039 0.001 0.0131 0.0074 0.0119 0.0021 0.0122 0.0007 0.0004 0.0037 0.0307 0.0257 0.0155 0.0019 0.0081 0.042
Bud 0.0002 0.0011 0.0028 0.0001 0.0008 0.0001 0.0026 0.0002 0.0008 0.0001 0 0.0017 0.0003 0.0013 0.0004 0.0001 0.0001 0.0009
Bud Neck 0.0008 0.0009 0.0005 0.0003 0.0015 0.0008 0.0006 0.0002 0.0003 0.0002 0.0001 0.0003 0.0013 0.0005 0.0005 0.0004 0.0004 0.0011
Bud Periphery 0.0002 0.0009 0.0009 0.0001 0.0019 0.0001 0.0006 0.0001 0.0004 0.0001 0 0.0005 0.0004 0.0012 0.0003 0 0.0001 0.0007
Bud Site 0.0014 0.0156 0.0019 0.0003 0.0005 0.0003 0.0033 0.0007 0.0009 0.0004 0.0001 0.0003 0.0028 0.0041 0.0012 0.0005 0.0004 0.0011
Cell Periphery 0.0001 0.0002 0.0001 0 0.0002 0 0.0002 0 0.0001 0 0 0 0.0002 0.0001 0 0 0 0.0001
Cytoplasm 0.0045 0.0083 0.0046 0.0011 0.0021 0.0007 0.0022 0.002 0.0015 0.0021 0.0005 0.0009 0.0037 0.0029 0.0016 0.0006 0.0006 0.0011
Cytoplasmic Foci 0.1689 0.2416 0.1596 0.1433 0.1135 0.1322 0.1463 0.1896 0.1495 0.1319 0.1416 0.1261 0.1558 0.2182 0.1871 0.1646 0.2103 0.1571
Eisosomes 0.0001 0.0001 0 0 0.0001 0 0.0001 0 0 0 0 0 0.0002 0 0 0 0 0.0002
Endoplasmic Reticulum 0.0006 0.0004 0.0003 0.0002 0.0014 0.0003 0.0015 0.0001 0.0001 0.0001 0.0001 0.0002 0.0034 0.0003 0.0002 0.0001 0.0001 0.0013
Endosome 0.2289 0.2275 0.2034 0.2393 0.1861 0.1105 0.1392 0.1624 0.1321 0.1149 0.1572 0.1048 0.1612 0.2039 0.1888 0.1708 0.2008 0.1011
Golgi 0.1468 0.1796 0.1967 0.2064 0.2191 0.154 0.1492 0.1822 0.1795 0.192 0.1676 0.1813 0.1627 0.238 0.294 0.2752 0.2133 0.2423
Lipid Particles 0.1408 0.0612 0.0975 0.0875 0.1493 0.1626 0.0901 0.0712 0.0588 0.1225 0.1049 0.0919 0.1965 0.0608 0.0503 0.1027 0.0881 0.1346
Mitochondria 0.0319 0.0309 0.0492 0.0679 0.0254 0.0168 0.0204 0.0241 0.0308 0.0375 0.0156 0.0318 0.0267 0.0155 0.0276 0.0075 0.003 0.0291
None 0.0029 0.0054 0.0013 0.0001 0.0012 0.0002 0.0032 0.0081 0.0011 0.0285 0.0001 0.0006 0.001 0.0003 0.0002 0.0001 0.0001 0.0008
Nuclear Periphery 0.0008 0.0003 0.0002 0.0001 0.0188 0.0003 0.0033 0.0001 0.0002 0.0002 0 0.0005 0.0121 0.0001 0.0001 0 0 0.0041
Nucleolus 0.0003 0.0021 0.0006 0.0001 0.0022 0.0001 0.0007 0.0001 0.0003 0.0002 0 0.0002 0.0005 0.0002 0.0001 0.0018 0 0.0005
Nucleus 0.0003 0.0006 0.0004 0 0.0219 0.0001 0.0008 0.0001 0.0002 0.0001 0 0.0001 0.0034 0.0001 0.0001 0.0001 0 0.0006
Peroxisomes 0.2493 0.2025 0.2721 0.2499 0.2327 0.4107 0.4191 0.3549 0.4277 0.3664 0.4102 0.4518 0.2322 0.2234 0.2297 0.2709 0.2736 0.2768
Punctate Nuclear 0.0032 0.0034 0.0013 0.0004 0.002 0.0011 0.0027 0.0006 0.0025 0.0005 0.0003 0.0022 0.0018 0.0012 0.0005 0.0016 0.0003 0.0025
Vacuole 0.0126 0.0031 0.0017 0.0011 0.0034 0.0007 0.0011 0.0007 0.0006 0.0008 0.0005 0.0006 0.0016 0.0014 0.0011 0.0007 0.0004 0.001
Vacuole Periphery 0.0014 0.001 0.001 0.0009 0.0029 0.0007 0.0008 0.0005 0.0005 0.0006 0.0005 0.0006 0.0015 0.0007 0.0008 0.0006 0.0004 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.5883 3.0728 5.3204 11.0403 4.4567 5.7258 9.3208 12.9313 9.3953 11.0563
Translational Efficiency 0.9623 1.9516 1.3892 0.4872 1.2899 1.3775 0.9524 0.553 0.8555 0.9989

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
130 1178 1193 1192 1626 2647 673 1225 1756 3825 1866 2417

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 977.48 809.04 882.11 892.30 687.40 846.47 862.85 939.08 708.88 834.94 875.16 916.01
Standard Deviation 151.69 113.79 118.68 136.06 86.31 103.23 117.64 114.76 119.88 107.99 118.67 127.87
Intensity Change Log 2 — -0.272856 -0.148109 -0.131538 — 0.300309 0.327960 0.450098 — -0.008142 0.067776 0.137513

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.015043 0.003165 0.008863 0.035292 0.001961 0.001893 0.004963 0.006149 0.002929 0.002285 0.007457 0.020522
Bud Neck 0.003925 0.000490 0.001122 0.001218 0.001584 0.000220 0.002125 0.000835 0.001758 0.000303 0.001483 0.001023
Bud Site 0.024205 0.001142 0.005403 0.012271 0.001457 0.000830 0.004564 0.004793 0.003141 0.000926 0.005100 0.008481
Cell Periphery 0.000119 0.000050 0.000056 0.000076 0.000066 0.000019 0.000047 0.000030 0.000070 0.000029 0.000053 0.000053
Cytoplasm 0.006773 0.000867 0.001564 0.004325 0.001219 0.000675 0.003767 0.002926 0.001630 0.000734 0.002359 0.003616
Cytoplasmic Foci 0.312212 0.329316 0.440328 0.330044 0.207768 0.279610 0.340672 0.356490 0.215500 0.294918 0.404385 0.343447
Eisosomes 0.000065 0.000049 0.000049 0.000075 0.000085 0.000035 0.000041 0.000031 0.000083 0.000040 0.000046 0.000053
Endoplasmic Reticulum 0.000371 0.000171 0.000573 0.000311 0.000138 0.000038 0.000182 0.000162 0.000156 0.000079 0.000432 0.000235
Endosome 0.223979 0.183702 0.205686 0.225079 0.183499 0.244024 0.310756 0.291059 0.186496 0.225447 0.243581 0.258519
Golgi 0.168657 0.315598 0.206533 0.193419 0.418607 0.363248 0.188381 0.170801 0.400103 0.348573 0.199986 0.181956
Lipid Particles 0.009961 0.035220 0.030498 0.010838 0.030900 0.012068 0.022727 0.009967 0.029350 0.019198 0.027695 0.010397
Mitochondria 0.002870 0.015121 0.007413 0.008409 0.042022 0.025213 0.006675 0.008168 0.039124 0.022105 0.007147 0.008287
Mitotic Spindle 0.057518 0.010410 0.035974 0.041266 0.004117 0.003389 0.035952 0.052878 0.008070 0.005551 0.035966 0.047151
None 0.000034 0.000203 0.000021 0.000212 0.000491 0.000018 0.000068 0.000016 0.000457 0.000075 0.000038 0.000113
Nuclear Periphery 0.000125 0.000032 0.000147 0.000057 0.000018 0.000013 0.000093 0.000066 0.000026 0.000019 0.000127 0.000062
Nuclear Periphery Foci 0.000529 0.000504 0.002604 0.000758 0.000641 0.000230 0.000730 0.000633 0.000632 0.000314 0.001928 0.000695
Nucleolus 0.000621 0.000541 0.000151 0.000072 0.001110 0.000076 0.000126 0.000146 0.001074 0.000219 0.000142 0.000109
Nucleus 0.000308 0.000190 0.000116 0.000062 0.000397 0.000017 0.000274 0.000052 0.000391 0.000070 0.000173 0.000057
Peroxisomes 0.146750 0.099704 0.046449 0.126025 0.101858 0.066467 0.067003 0.086053 0.105181 0.076703 0.053862 0.105766
Vacuole 0.021759 0.001902 0.005242 0.008535 0.001175 0.001102 0.009112 0.007366 0.002699 0.001349 0.006638 0.007943
Vacuole Periphery 0.004175 0.001621 0.001208 0.001657 0.000888 0.000815 0.001741 0.001378 0.001131 0.001063 0.001400 0.001516

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.78 0.91 -2.68 -9.20 -7.09 0.16 -2.68 -3.41 -3.39 -0.73 1.07 -4.13 -9.15 -9.79 -6.30
Bud Neck 2.89 2.43 2.33 -4.73 -0.61 3.28 -0.59 1.69 -5.15 1.48 3.78 0.61 1.82 -7.55 1.20
Bud Site 3.98 3.31 2.19 -8.51 -4.43 1.92 -3.81 -4.73 -5.74 -0.01 4.20 -2.04 -5.67 -10.18 -3.48
Cell Periphery 1.95 1.80 1.24 -2.94 -2.50 8.47 1.62 6.13 -4.05 1.97 6.90 2.41 2.54 -5.73 0.02
Cytoplasm 3.21 2.83 1.25 -7.25 -5.30 2.39 -2.45 -3.16 -4.14 0.81 3.79 -1.64 -4.95 -7.86 -2.25
Cytoplasmic Foci -1.06 -7.02 -1.06 -0.02 12.88 -15.29 -16.11 -21.56 -11.08 -1.56 -17.90 -31.38 -23.46 -9.36 9.48
Eisosomes 1.46 1.43 -0.65 -6.16 -5.70 4.90 4.04 5.34 1.53 2.54 4.70 3.89 3.26 -5.09 -2.01
Endoplasmic Reticulum 1.99 -1.21 0.58 -4.02 1.96 4.64 -1.01 -0.35 -2.58 0.54 3.59 -3.19 -2.16 -5.39 2.26
Endosome 2.00 0.83 -0.16 -5.56 -2.47 -10.40 -12.52 -13.52 -6.07 1.67 -7.43 -8.82 -11.66 -6.05 -2.31
Golgi -8.34 -2.30 -1.50 15.69 1.97 7.61 25.89 32.80 30.45 2.07 7.58 28.77 32.21 34.04 3.50
Lipid Particles -5.21 -4.58 -0.26 6.82 6.48 6.63 2.00 7.00 1.12 3.93 3.67 0.51 7.15 5.40 7.68
Mitochondria -6.88 -2.78 -4.24 3.50 -0.56 5.27 11.87 11.43 8.03 -0.82 6.05 11.85 11.74 9.06 -0.87
Mitotic Spindle 3.83 1.67 1.20 -8.16 -1.18 1.09 -6.95 -11.45 -11.68 -2.80 2.05 -9.32 -13.32 -14.91 -3.02
None -1.19 0.88 -0.93 -0.10 -1.01 1.41 1.22 1.41 -0.09 1.57 1.22 1.34 1.03 -0.42 -0.78
Nuclear Periphery 1.51 -0.14 1.14 -2.19 2.94 1.92 -4.48 -4.87 -5.44 1.38 1.26 -4.94 -4.48 -6.52 3.14
Nuclear Periphery Foci -0.73 -2.76 -1.06 0.04 2.25 1.43 -0.92 0.01 -2.23 0.97 0.80 -2.49 -0.28 -1.49 2.52
Nucleolus 0.13 0.92 1.02 1.23 0.64 2.57 1.90 1.19 -1.02 -0.44 2.18 2.38 1.95 -0.20 -0.44
Nucleus 0.77 1.34 1.59 1.03 0.87 2.62 0.39 2.27 -2.23 2.30 2.31 1.43 2.40 0.07 2.40
Peroxisomes 2.34 5.09 1.03 -3.21 -11.17 6.93 5.14 2.51 -3.58 -2.67 5.80 9.99 -0.05 -6.23 -10.63
Vacuole 4.18 3.54 2.84 -8.06 -3.65 0.67 -6.02 -8.08 -8.18 1.22 3.45 -5.08 -7.65 -12.08 -1.71
Vacuole Periphery 1.14 1.32 1.13 -0.07 -1.13 0.73 -2.92 -2.50 -2.86 1.06 0.37 -1.09 -1.29 -1.81 -0.48
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; involved in localization of actin and chitin; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Vps52

Vps52


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vps52-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available