Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L37B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; protein abundance increases in response to DNA replication stress; homologous to mammalian ribosomal protein L37, no bacterial homolog; RPL37B has a paralog, RPL37A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0.05 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0.06 0.05 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.98 0.97 0.93 0.88 0.82 – 0.73 0.66 0.66 0.61 0.97 0.97 0.99 1.0 0.99 0.99 0.96 0.96 0.95 0.91 0.93 0.9
Endoplasmic Reticulum 0 0 0 0 0.06 0.07 0.17 – 0.19 0.24 0.26 0.28 0 0 0 0 0.05 0.08 0 0 0 0 0.05 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0.06 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 8 5 – 12 25 26 37 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 1 1 0 – 2 0 0 4 0 2 1 0 0 0 0 0 0 3 3 4
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 6 8 13 11 20 – 28 29 39 42 1 9 4 0 3 0 0 0 1 1 2 1
Cytoplasm 221 350 410 410 423 420 519 – 330 361 405 391 267 452 402 75 109 104 206 332 388 283 373 269
Endoplasmic Reticulum 2 2 9 13 29 34 108 – 86 132 158 177 9 11 6 3 5 8 4 1 10 11 18 8
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 1 0 1 3 0 9 3 – 19 35 46 44 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 1 0 0 0 2 0 – 3 7 11 12 0 0 0 0 1 0 0 2 0 0 0 0
Nucleus 0 0 0 0 0 1 1 – 2 0 0 0 0 1 0 0 0 0 0 1 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 1 0 – 0 1 1 0 0 1 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 1 1 3 0 0 6 0 – 1 2 5 8 0 0 1 0 0 0 1 2 1 4 2 6
Unique Cell Count 223 352 420 424 456 475 633 450 544 615 640 275 464 406 75 110 105 216 345 407 311 403 298
Labelled Cell Count 225 354 429 435 466 493 656 483 592 691 715 277 476 415 78 118 112 216 345 407 311 403 298


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 95.1 96.8 78.1 69.7 56.1 35.6 39.3 – 35.9 35.0 35.2 33.3 89.8 70.4 85.2 127.7 133.1 138.3 86.9 93.1 95.6
Std Deviation (1e-4) 17.1 17.7 16.6 13.5 9.7 9.4 7.7 – 7.9 7.1 7.9 7.1 19.7 16.1 18.1 40.4 34.1 31.0 18.0 20.4 27.1
Intensity Change (Log2) – – – -0.16 -0.48 -1.13 -0.99 – -1.12 -1.16 -1.15 -1.23 0.2 -0.15 0.13 0.71 0.77 0.82 0.15 0.25 0.29

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 3.4 4.5 4.3 5.0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.5 1.4 1.0 1.8 – 3.6 3.2 3.8 3.9 0 0.6 0 0 0 0
Cytoplasm -0.8 -3.3 -5.3 -7.7 – -10.0 -12.0 -12.3 -13.5 -0.4 -0.2 1.6 1.4 1.0 0.9
Endoplasmic Reticulum 0.8 3.1 3.5 7.5 – 8.0 9.6 10.1 10.7 0.9 0.2 -0.7 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 3.9 5.0 5.5 5.2 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 71.9981 94.2758 85.9922 83.9816 72.1358 75.4586 85.265 107.7793 98.9787 101.0594 69.9928 94.5226 94.4194 112.9938 105.0068 99.7469 80.1975 101.9105
Actin 0.0065 0.0007 0.0013 0.0002 0.0004 0.0017 0.0036 0.0026 0.0016 0.0002 0.0175 0.0015 0.0101 0.0008 0.0047 0.0009 0.0468 0.003
Bud 0.0026 0.0004 0.001 0.0008 0.0005 0.0012 0.0015 0.0005 0.0036 0.0015 0.0029 0.0005 0.0031 0.0004 0.0009 0.0014 0.0075 0.0005
Bud Neck 0.0012 0.0004 0.0007 0.0006 0.0012 0.0012 0.0006 0.0004 0.0007 0.0013 0.0016 0.001 0.0009 0.0005 0.0006 0.0007 0.0012 0.0008
Bud Periphery 0.0039 0.0002 0.0011 0.0004 0.0003 0.0007 0.0016 0.0004 0.0018 0.0011 0.0014 0.0014 0.0049 0.0003 0.0004 0.0007 0.0114 0.0002
Bud Site 0.0014 0.0003 0.0005 0.0002 0.0004 0.0003 0.0014 0.0012 0.0012 0.0003 0.0018 0.0001 0.0007 0.0003 0.0004 0.0003 0.0073 0
Cell Periphery 0.011 0.0049 0.0059 0.0059 0.0098 0.0023 0.0122 0.0078 0.0043 0.0137 0.0017 0.0031 0.0151 0.0044 0.0029 0.0119 0.0038 0.0003
Cytoplasm 0.6605 0.9465 0.8432 0.699 0.6515 0.8554 0.7468 0.933 0.8752 0.7547 0.6977 0.8774 0.7511 0.9157 0.8658 0.7653 0.5172 0.8571
Cytoplasmic Foci 0.0206 0.0016 0.0064 0.0021 0.0481 0.0116 0.0032 0.0011 0.0047 0.0045 0.01 0.0062 0.0028 0.0012 0.0067 0.0029 0.0092 0.0056
Eisosomes 0.0002 0 0.0001 0.0001 0.0001 0.0002 0.0004 0 0 0 0.0002 0.0001 0.0002 0.0001 0.0001 0 0.0006 0
Endoplasmic Reticulum 0.0649 0.0092 0.0222 0.0484 0.0325 0.003 0.0575 0.0127 0.0173 0.0046 0.0168 0.0639 0.0537 0.0318 0.0158 0.0049 0.0263 0.053
Endosome 0.0192 0.0028 0.0127 0.0087 0.0281 0.0096 0.0148 0.002 0.0067 0.0152 0.081 0.0163 0.0088 0.0037 0.0054 0.0128 0.0203 0.0287
Golgi 0.004 0.0007 0.0047 0.002 0.0016 0.0012 0.0024 0.0014 0.0009 0.001 0.0187 0.0016 0.0015 0.0018 0.0008 0.001 0.0137 0.0146
Lipid Particles 0.0105 0.0006 0.0024 0.0007 0.0186 0.0072 0.0025 0.0005 0.0006 0.0007 0.0026 0.0004 0.0006 0.0003 0.0026 0.0006 0.0096 0.0001
Mitochondria 0.0107 0.0002 0.0085 0.0024 0.0046 0.0264 0.0074 0.002 0.0018 0.0003 0.0215 0.0012 0.0068 0.0017 0.0016 0.0084 0.0664 0.0066
None 0.0041 0.0001 0.0019 0.0029 0.0078 0.0033 0.0029 0.0002 0.0017 0.0002 0.002 0.0002 0.0037 0.0002 0.0031 0.0003 0.0057 0.0007
Nuclear Periphery 0.0309 0.0018 0.0064 0.0135 0.0336 0.0056 0.0251 0.002 0.0029 0.005 0.0139 0.0034 0.0269 0.0024 0.0088 0.0054 0.0055 0.0061
Nucleolus 0.0065 0.0001 0.004 0.0048 0.0329 0.0129 0.0009 0.0002 0.0048 0.0002 0.0111 0 0.0006 0.0002 0.0017 0.0004 0.0152 0
Nucleus 0.0101 0.001 0.0029 0.0062 0.0154 0.006 0.0087 0.0024 0.0035 0.0032 0.0165 0.0012 0.0076 0.0012 0.0042 0.003 0.0084 0.0012
Peroxisomes 0.0024 0 0.0005 0.0001 0.0012 0.0014 0.0001 0 0.0002 0.0001 0.0005 0.0001 0.0001 0 0.0051 0.0001 0.0042 0.0001
Punctate Nuclear 0.0051 0 0.0002 0.0001 0.0022 0.0012 0.0027 0 0.0016 0 0.0005 0 0.0001 0 0.001 0 0.0011 0.0001
Vacuole 0.1008 0.0259 0.0614 0.1535 0.0752 0.0343 0.0854 0.0277 0.0555 0.1657 0.0509 0.0169 0.0771 0.0281 0.054 0.1156 0.172 0.0127
Vacuole Periphery 0.0229 0.0025 0.0119 0.0475 0.0339 0.0134 0.0181 0.002 0.0091 0.0266 0.0292 0.0035 0.0237 0.0048 0.0137 0.0636 0.0464 0.0086

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1245.9792 975.2933 1532.4005 1613.016 1736.0237 925.1901 1205.5667 1239.1073 1203.4632 1355.389
Translational Efficiency 1.9931 2.6913 1.7137 1.4908 1.8719 2.8199 1.7815 1.7982 1.7849 1.7458

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
262 1023 118 1766 1837 2740 2233 1970 2099 3763 2351 3736

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 4293.73 5629.08 7999.03 6804.96 4688.67 5466.86 7281.01 7905.08 4639.37 5510.96 7317.05 7385.06
Standard Deviation 1132.26 1159.49 1194.34 1724.66 947.01 1104.16 1311.85 1716.12 980.79 1121.80 1315.58 1805.72
Intensity Change Log 2 — 0.390668 0.897594 0.664355 — 0.221534 0.634960 0.753601 — 0.304859 0.766475 0.711628

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000292 0.000102 0.000183 0.000201 0.000049 0.000085 0.000114 0.000164 0.000080 0.000090 0.000118 0.000182
Bud Neck 0.000589 0.000689 0.006926 0.002334 0.000303 0.000216 0.000440 0.000685 0.000339 0.000345 0.000766 0.001464
Bud Site 0.008835 0.003912 0.002178 0.011345 0.002088 0.003965 0.003072 0.006322 0.002930 0.003951 0.003027 0.008697
Cell Periphery 0.062906 0.024890 0.064772 0.015784 0.009311 0.002751 0.062610 0.049880 0.016001 0.008770 0.062718 0.033763
Cytoplasm 0.154006 0.591185 0.153266 0.368288 0.651891 0.811470 0.516431 0.512262 0.589744 0.751584 0.498203 0.444206
Cytoplasmic Foci 0.021014 0.013554 0.013311 0.004579 0.013561 0.014545 0.002969 0.005191 0.014491 0.014275 0.003489 0.004902
Eisosomes 0.000009 0.000003 0.000018 0.000003 0.000001 0.000001 0.000003 0.000004 0.000002 0.000001 0.000004 0.000004
Endoplasmic Reticulum 0.007272 0.001651 0.000374 0.001128 0.001896 0.001222 0.002335 0.001695 0.002567 0.001339 0.002237 0.001427
Endosome 0.002431 0.001274 0.000673 0.001739 0.001140 0.000999 0.000538 0.000844 0.001301 0.001073 0.000544 0.001267
Golgi 0.309013 0.105431 0.047370 0.021568 0.098569 0.032301 0.023285 0.019624 0.124837 0.052182 0.024493 0.020543
Lipid Particles 0.040987 0.021645 0.027478 0.018000 0.011398 0.003894 0.024530 0.029510 0.015091 0.008720 0.024678 0.024069
Mitochondria 0.000370 0.000737 0.000177 0.000498 0.000186 0.000579 0.000299 0.000542 0.000209 0.000622 0.000293 0.000521
Mitotic Spindle 0.002255 0.001377 0.001360 0.001547 0.001725 0.001561 0.000363 0.000667 0.001791 0.001511 0.000413 0.001083
None 0.002202 0.002831 0.000916 0.001671 0.001597 0.002316 0.000684 0.000843 0.001673 0.002456 0.000695 0.001235
Nuclear Periphery 0.001088 0.001030 0.007397 0.000563 0.000618 0.000187 0.000699 0.000523 0.000677 0.000416 0.001036 0.000542
Nuclear Periphery Foci 0.013254 0.021299 0.022526 0.008704 0.016783 0.005444 0.006841 0.005622 0.016343 0.009754 0.007628 0.007079
Nucleolus 0.000322 0.000222 0.000193 0.000329 0.000049 0.000059 0.000130 0.000180 0.000083 0.000103 0.000133 0.000250
Nucleus 0.003562 0.007724 0.022855 0.011986 0.002527 0.002627 0.002862 0.003734 0.002656 0.004013 0.003865 0.007635
Peroxisomes 0.000038 0.000040 0.000012 0.000083 0.000016 0.000029 0.000156 0.000186 0.000019 0.000032 0.000149 0.000137
Vacuole 0.104261 0.104052 0.480959 0.451731 0.068234 0.049950 0.276260 0.297918 0.072731 0.064658 0.286534 0.370625
Vacuole Periphery 0.265294 0.096352 0.147057 0.077918 0.118058 0.065799 0.075381 0.063605 0.136437 0.074105 0.078978 0.070371

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.89 0.90 0.56 -4.26 -0.92 -1.43 -2.90 -5.42 -2.85 -1.47 -0.59 -1.99 -5.71 -4.30 -2.05
Bud Neck -1.03 -4.47 -10.23 -10.31 2.55 1.50 -2.68 -7.14 -8.94 -5.05 -0.22 -4.79 -12.83 -13.18 -7.91
Bud Site 1.33 1.74 -0.84 -7.76 -9.18 -4.88 -3.06 -7.84 -4.40 -5.65 -1.94 -0.46 -8.81 -8.69 -9.80
Cell Periphery 5.67 0.02 7.62 6.76 8.08 12.31 -26.11 -18.73 -22.51 5.21 6.53 -21.61 -10.02 -18.05 13.99
Cytoplasm -22.37 -0.14 -12.68 15.32 -9.29 -17.07 12.62 12.77 32.35 0.50 -17.00 8.58 14.43 40.11 5.18
Cytoplasmic Foci 2.64 1.02 5.99 8.63 2.92 -0.90 14.18 6.56 7.64 -4.86 0.29 14.21 10.24 11.81 -4.53
Eisosomes 2.27 -2.64 1.81 -3.00 5.26 0.89 -6.30 -4.38 -4.52 -1.64 1.75 -4.20 -3.99 -6.05 -0.39
Endoplasmic Reticulum 3.84 4.82 4.40 2.11 -4.99 2.19 -1.27 0.90 -1.36 2.32 3.81 1.03 4.17 0.19 3.80
Endosome 4.32 6.65 2.71 -2.65 -6.97 1.60 9.10 2.04 1.18 -2.10 2.82 11.19 0.60 -1.46 -7.10
Golgi 14.17 18.57 21.10 20.61 7.57 19.95 23.75 25.06 8.49 3.26 18.88 27.79 29.74 19.96 5.26
Lipid Particles 3.92 2.20 5.09 2.57 3.53 9.06 -10.31 -11.33 -17.61 -2.84 6.12 -7.19 -6.56 -14.06 0.93
Mitochondria -0.64 0.98 -0.81 0.31 -3.22 -4.13 -2.05 -3.98 -0.07 -2.21 -2.62 -1.58 -4.51 0.24 -2.63
Mitotic Spindle 1.70 1.26 0.16 -1.65 -1.16 0.27 6.12 2.52 1.96 -2.34 0.84 6.60 0.94 0.20 -4.16
None -0.56 1.41 0.60 2.20 -1.87 -1.64 9.88 3.89 3.03 -1.44 -2.16 6.94 1.74 3.08 -2.93
Nuclear Periphery 0.27 -5.50 3.34 3.49 5.85 10.30 -2.17 1.17 -9.64 3.57 5.79 -4.87 1.26 -4.26 5.52
Nuclear Periphery Foci -4.63 -2.90 2.87 8.38 4.29 13.15 12.20 13.34 -0.83 2.24 7.79 11.47 11.58 4.11 0.33
Nucleolus 0.39 0.49 -0.25 -1.28 -5.20 -1.53 -9.96 -8.18 -7.22 -3.57 -0.42 -1.64 -6.02 -4.78 -8.78
Nucleus -2.42 -4.66 -8.62 -7.20 0.77 -0.51 -2.19 -5.80 -5.60 -4.73 -3.47 -4.10 -12.13 -10.35 -10.03
Peroxisomes -0.05 2.58 -3.20 -2.15 -9.12 -3.14 -9.36 -8.55 -7.99 -1.19 -2.30 -9.15 -10.19 -8.73 0.87
Vacuole -0.15 -15.29 -31.25 -38.34 1.36 5.42 -35.51 -35.21 -39.27 -2.66 2.28 -37.07 -54.08 -57.69 -11.09
Vacuole Periphery 12.23 6.95 15.00 6.67 5.38 11.99 10.10 13.91 1.65 4.96 14.52 13.43 18.24 4.57 5.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L37B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; protein abundance increases in response to DNA replication stress; homologous to mammalian ribosomal protein L37, no bacterial homolog; RPL37B has a paralog, RPL37A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl37b

Rpl37b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl37b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available