Standard name
Human Ortholog
Description Lipid phosphate phosphatase; catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0.08 0 0 0 0 0
Bud 0 0 0.05 0.07 0 0.09 0.06 0.08 0.07 0.05 0.07 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.89 0.78 0.47 0.51 0.48 0.51 0.45 0.42 0.44 0.41 0.41 0.4 0.72 0.64 0.6 0.34 0.44 0.43 0.21 0.24 0.11 0.16 0.19 0.23
Endoplasmic Reticulum 0.11 0 0 0 0 0 0 0 0 0 0 0 0.1 0.05 0 0 0 0.06 0 0 0 0 0 0
Endosome 0 0.05 0 0.11 0.09 0 0 0 0 0 0 0 0.07 0.18 0.2 0.32 0.25 0.24 0.13 0.18 0.32 0.14 0.12 0.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.09 0.05 0 0
Mitochondria 0 0.16 0.59 0.42 0.43 0.6 0.64 0.64 0.6 0.64 0.7 0.72 0 0 0.05 0.09 0.09 0.05 0.11 0.27 0.26 0.35 0.38 0.35
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.07 0.05 0 0 0.09 0.08 0.05 0.06 0.05 0.06 0.05 0.1 0.12 0.07 0.06 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.29 0.24 0.38 0.33 0.14 0.07 0.19 0.17 0.17
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 3 0 0 0 0 1 0 2 0 0 0 8 3 5 1 2 6 3 4 7 4 9 7
Bud 0 1 7 12 10 25 21 29 22 19 18 24 2 4 5 2 3 3 0 2 1 2 2 3
Bud Neck 0 0 0 0 1 1 2 4 2 1 0 3 1 0 0 0 1 0 0 1 1 0 2 3
Bud Site 0 0 0 0 0 3 6 4 8 3 3 4 0 0 0 1 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 1 0 0 0 2 1 2 1 1 1 1 0 0 0 0 0 0 0
Cytoplasm 16 90 66 83 112 137 167 159 139 153 106 161 86 125 137 56 61 69 9 32 18 26 57 67
Endoplasmic Reticulum 2 4 3 0 1 4 3 3 2 1 0 3 12 9 8 4 6 9 0 1 1 4 6 4
Endosome 0 6 1 18 22 5 1 3 1 2 1 1 8 34 47 53 35 39 6 24 52 22 37 29
Golgi 0 1 1 0 0 0 0 0 0 0 0 0 1 7 4 6 2 5 2 5 14 7 5 11
Mitochondria 0 18 83 69 100 162 237 245 190 235 181 290 5 7 12 15 13 8 5 37 42 57 116 103
Nucleus 0 0 0 0 1 2 1 1 1 2 1 1 0 0 2 2 1 0 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 1 0 0 0 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 2 0 0 2 2 2 0 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 2 12 18 5 4 6 6 1 2 4 0 6 0 1 1 2 1 1 5 3 0 2
SpindlePole 0 1 4 12 11 12 14 36 25 18 15 22 7 9 22 20 9 9 0 4 5 1 9 4
Vac/Vac Membrane 1 4 2 2 2 3 4 3 2 5 2 4 2 8 6 48 33 61 14 18 12 30 51 49
Unique Cell Count 18 115 141 164 234 269 368 382 317 369 259 403 120 194 230 167 138 161 46 137 165 164 306 295
Labelled Cell Count 19 128 170 208 279 361 462 493 403 444 333 518 134 213 249 211 168 212 46 137 165 164 306 295


Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 4.9 3.7 3.7 3.8 3.6 2.9 3.1 3.1 2.9 2.9 3.0 5.3 5.4 5.5 6.1 6.3 6.4 5.6 5.5 5.8
Std Deviation (1e-4) 3.0 1.2 0.9 0.9 1.3 1.3 0.6 0.8 1.3 0.6 0.9 0.7 1.0 0.9 1.0 1.2 1.6 1.3 1.1 1.2 1.5
Intensity Change (Log2) – – – -0.03 0.03 -0.04 -0.35 -0.27 -0.29 -0.36 -0.37 -0.34 0.51 0.53 0.55 0.71 0.76 0.77 0.58 0.56 0.63

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.7 0.2 0.8 -0.3 -1.1 -0.6 -1.1 -1.1 -1.4 4.1 3.2 2.4 -2.4 -0.4 -0.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 2.7 1.2 0 0 0 1.5
Endosome 0 0 0 0 0 0 0 0 0 0 5.0 5.5 7.1 6.1 6.0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -9.3 -11.3 -11.5 -9.4 -8.7 -10.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 1.2 0.8 2.5 3.0 1.5 1.2
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 6.5 5.7 7.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.4945 -0.0188 0.0696 -0.3044 -0.5631 -0.0065 1.1118 1.4459 1.3233 0.8956 0.9253 1.1722 -1.5373 -0.5562 -0.7045 -0.8622 -1.1502 -0.9892
Actin 0.0271 0.0084 0.0068 0.0316 0.003 0.0109 0.0363 0.0114 0.0083 0.024 0.0071 0.0078 0.0105 0.0011 0.0047 0.0008 0.0036 0.007
Bud 0.0003 0.0036 0.0031 0.0011 0.0007 0.0006 0.0012 0.0045 0.0034 0.0004 0.0009 0.0015 0.0003 0.0005 0.0019 0.0002 0.0001 0.0002
Bud Neck 0.0011 0.0005 0.0004 0.0003 0.0006 0.0009 0.0081 0.0008 0.0077 0.0002 0.0006 0.0013 0.0009 0.0003 0.0003 0.0003 0.0002 0.001
Bud Periphery 0.0005 0.0044 0.0013 0.0023 0.0012 0.001 0.0018 0.0047 0.0072 0.0008 0.0016 0.0045 0.0005 0.0006 0.0021 0.0003 0.0001 0.0002
Bud Site 0.0011 0.0185 0.0022 0.0006 0.0026 0.0003 0.0095 0.0166 0.0086 0.0002 0.0014 0.0005 0.0008 0.0014 0.0009 0.0002 0.0002 0.0002
Cell Periphery 0.0002 0.0004 0.0003 0.0002 0.0003 0.0001 0.0005 0.0003 0.0004 0.0002 0.0002 0.0002 0.0002 0.0001 0.0002 0.0001 0 0.0001
Cytoplasm 0.0629 0.0697 0.0783 0.0771 0.1281 0.1021 0.0736 0.0774 0.0502 0.0979 0.0781 0.1237 0.0848 0.1609 0.0792 0.0959 0.0839 0.1334
Cytoplasmic Foci 0.2269 0.1804 0.1926 0.1263 0.1527 0.2037 0.2341 0.2575 0.1931 0.1418 0.2227 0.2361 0.2135 0.2242 0.2127 0.2424 0.2011 0.2389
Eisosomes 0.0007 0.0003 0.0003 0.0003 0.0003 0.0003 0.0006 0.0001 0.0005 0.0002 0.0003 0.0002 0.001 0.0002 0.0004 0 0.0002 0.0002
Endoplasmic Reticulum 0.0044 0.0036 0.0035 0.0032 0.0052 0.0026 0.0047 0.0023 0.0033 0.0028 0.0022 0.002 0.0042 0.0028 0.0035 0.004 0.0017 0.0025
Endosome 0.2173 0.2924 0.2634 0.2689 0.1959 0.162 0.2164 0.2671 0.2742 0.3268 0.2828 0.2077 0.257 0.2801 0.285 0.2992 0.2843 0.2245
Golgi 0.0434 0.0656 0.0631 0.0366 0.0578 0.0325 0.0496 0.0782 0.1006 0.067 0.0446 0.0652 0.0513 0.0446 0.0877 0.0498 0.0519 0.0557
Lipid Particles 0.0341 0.0355 0.0194 0.0084 0.0239 0.0299 0.0325 0.0281 0.0168 0.0156 0.0274 0.0175 0.0413 0.0063 0.0332 0.0096 0.0474 0.0207
Mitochondria 0.0192 0.0154 0.0232 0.0533 0.0234 0.0103 0.0245 0.0139 0.0325 0.0222 0.0174 0.0207 0.0158 0.0063 0.0252 0.0113 0.0041 0.0145
None 0.3071 0.2587 0.2994 0.3246 0.2919 0.3673 0.2356 0.1805 0.2321 0.2261 0.1802 0.2443 0.27 0.2413 0.2093 0.2087 0.2557 0.2516
Nuclear Periphery 0.0038 0.0017 0.0026 0.0026 0.0056 0.0049 0.0082 0.0006 0.0015 0.0015 0.0007 0.0005 0.0019 0.0009 0.002 0.0011 0.0008 0.0018
Nucleolus 0.0008 0.0006 0.0014 0.0013 0.0038 0.0004 0.0012 0.0006 0.0005 0.0002 0.0004 0.0002 0.0005 0.0003 0.0004 0.0002 0.0002 0.0003
Nucleus 0.0061 0.0008 0.0024 0.0029 0.0064 0.0027 0.0025 0.0007 0.001 0.0007 0.0006 0.0006 0.0009 0.0008 0.0008 0.0006 0.0004 0.0018
Peroxisomes 0.0308 0.0262 0.0253 0.0356 0.0718 0.0599 0.0433 0.0456 0.0462 0.0521 0.1164 0.0583 0.0336 0.015 0.0382 0.0554 0.0589 0.0357
Punctate Nuclear 0.0066 0.0014 0.0024 0.0024 0.008 0.0028 0.0053 0.0015 0.0012 0.0007 0.0027 0.0015 0.0035 0.0009 0.0019 0.0007 0.0015 0.0031
Vacuole 0.0041 0.009 0.0057 0.0124 0.0121 0.0032 0.0074 0.0061 0.0072 0.0111 0.0086 0.0039 0.0056 0.0091 0.0072 0.0153 0.0027 0.0047
Vacuole Periphery 0.0015 0.0028 0.0028 0.0081 0.0045 0.0016 0.0031 0.0017 0.0034 0.0073 0.0033 0.0017 0.0017 0.0023 0.0031 0.0042 0.001 0.0019

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.7616 13.1517 7.0975 14.0586 25.1441 36.0914 12.0888 9.7909 12.3511 20.3363
Translational Efficiency 0.9463 0.6591 0.8705 1.2281 0.9067 0.8457 0.9226 0.9733 0.8228 0.8896

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1802 1595 1311 1073 1495 1462 1621 1732 3297 3057 2932 2805

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 658.91 718.07 868.86 861.13 687.99 666.18 879.15 865.90 672.10 693.25 874.55 864.08
Standard Deviation 75.10 93.77 115.14 114.96 77.57 90.35 100.37 114.78 77.59 95.72 107.35 114.87
Intensity Change Log 2 — 0.124043 0.399042 0.386150 — -0.046476 0.353722 0.331813 — 0.039462 0.376071 0.358650

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000443 0.000739 0.004275 0.004017 0.000725 0.001221 0.005008 0.004331 0.000571 0.000970 0.004680 0.004211
Bud Neck 0.024737 0.018862 0.012364 0.012063 0.017577 0.033293 0.011105 0.013763 0.021491 0.025763 0.011668 0.013113
Bud Site 0.011372 0.008124 0.013019 0.036709 0.005355 0.014009 0.016312 0.024812 0.008644 0.010939 0.014839 0.029363
Cell Periphery 0.000168 0.000089 0.000170 0.000119 0.000149 0.000198 0.000086 0.000088 0.000160 0.000141 0.000124 0.000100
Cytoplasm 0.307200 0.238369 0.226322 0.171132 0.257910 0.186224 0.150968 0.219898 0.284850 0.213431 0.184661 0.201243
Cytoplasmic Foci 0.384102 0.429615 0.203447 0.210691 0.446310 0.424169 0.263244 0.253734 0.412310 0.427010 0.236507 0.237268
Eisosomes 0.000438 0.000165 0.000109 0.000085 0.000519 0.000451 0.000087 0.000117 0.000475 0.000302 0.000097 0.000105
Endoplasmic Reticulum 0.001201 0.000799 0.007405 0.002322 0.001130 0.000807 0.004112 0.001407 0.001169 0.000803 0.005585 0.001757
Endosome 0.042944 0.058303 0.083600 0.121936 0.047186 0.072094 0.105650 0.110388 0.044867 0.064899 0.095790 0.114805
Golgi 0.020088 0.033607 0.015300 0.021706 0.037276 0.046795 0.034460 0.031816 0.027882 0.039914 0.025893 0.027949
Lipid Particles 0.028175 0.019752 0.028688 0.010405 0.031126 0.028061 0.030815 0.016267 0.029513 0.023726 0.029864 0.014024
Mitochondria 0.016701 0.019863 0.002786 0.005516 0.015283 0.047670 0.006031 0.008001 0.016058 0.033161 0.004580 0.007050
Mitotic Spindle 0.000894 0.008751 0.105976 0.123969 0.001224 0.007694 0.146746 0.058624 0.001044 0.008246 0.128516 0.083621
None 0.001087 0.001511 0.003337 0.002975 0.000914 0.001067 0.001115 0.002269 0.001008 0.001299 0.002109 0.002539
Nuclear Periphery 0.000431 0.000486 0.004087 0.001657 0.000321 0.000342 0.002890 0.000942 0.000381 0.000417 0.003425 0.001215
Nuclear Periphery Foci 0.000205 0.000420 0.013496 0.003651 0.000272 0.000621 0.005831 0.001209 0.000235 0.000516 0.009258 0.002143
Nucleolus 0.000740 0.001260 0.006925 0.001563 0.000687 0.001124 0.002058 0.001492 0.000716 0.001195 0.004234 0.001519
Nucleus 0.069666 0.053349 0.126854 0.042827 0.053529 0.030883 0.061956 0.039436 0.062349 0.042605 0.090974 0.040733
Peroxisomes 0.022103 0.039594 0.026897 0.044086 0.030915 0.051560 0.050611 0.067113 0.026099 0.045317 0.040007 0.058304
Vacuole 0.065178 0.062778 0.112996 0.178738 0.049305 0.046917 0.098818 0.141435 0.057980 0.055192 0.105157 0.155705
Vacuole Periphery 0.002127 0.003563 0.001948 0.003834 0.002288 0.004803 0.002098 0.002858 0.002200 0.004156 0.002031 0.003232

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.83 -7.49 -3.71 -3.19 1.64 -1.91 -6.19 -4.96 -3.55 1.64 -2.66 -9.45 -6.33 -5.02 2.30
Bud Neck 3.15 6.72 7.05 4.00 0.65 -6.17 3.26 1.82 7.76 -1.92 -2.66 7.43 6.57 8.40 -1.14
Bud Site 1.92 -1.36 -5.53 -7.43 -5.19 -6.61 -6.90 -7.46 -2.61 -1.85 -2.01 -4.85 -8.10 -7.41 -4.82
Cell Periphery 3.97 -0.26 3.27 -0.94 6.14 -2.70 5.91 5.84 6.80 1.47 1.31 2.69 5.80 5.38 5.56
Cytoplasm 7.65 8.04 11.38 4.21 3.38 8.56 11.06 2.01 -6.12 -8.53 11.50 14.29 9.21 -1.47 -4.23
Cytoplasmic Foci -5.31 26.37 28.19 32.12 3.06 2.60 26.96 30.61 27.58 3.61 -2.33 36.38 39.82 41.22 4.10
Eisosomes 9.03 10.95 12.06 11.38 5.74 1.26 9.77 9.44 10.69 -1.42 5.75 14.58 14.71 12.67 1.39
Endoplasmic Reticulum 1.99 -14.26 -5.73 -9.36 11.55 1.65 -9.32 -1.62 -3.32 8.10 2.58 -16.55 -4.29 -7.54 13.94
Endosome -5.06 -7.80 -7.85 -4.64 -1.52 -6.77 -10.72 -8.50 -2.17 1.82 -8.47 -13.53 -11.97 -5.19 0.24
Golgi -5.25 4.21 3.67 8.10 -0.16 -2.76 3.55 5.67 8.38 2.12 -5.62 4.32 5.71 10.78 1.40
Lipid Particles 4.60 0.70 12.54 9.22 10.97 1.23 1.18 8.99 7.19 7.67 3.81 1.20 13.87 9.99 12.04
Mitochondria -1.54 9.52 8.17 11.69 -1.66 -9.55 5.77 5.35 13.55 -0.60 -8.86 10.52 9.27 16.83 -1.63
Mitotic Spindle -6.08 -16.88 -14.72 -13.30 -0.45 -4.16 -21.94 -13.83 -11.43 11.20 -7.22 -27.60 -20.08 -17.42 8.30
None -1.28 -3.79 -2.46 -1.38 0.75 -0.84 -1.23 -2.61 -2.21 -1.98 -1.48 -3.81 -3.46 -2.25 -0.54
Nuclear Periphery -1.00 -14.53 -7.39 -7.14 5.72 -0.33 -11.47 -13.29 -12.08 6.65 -0.94 -17.79 -13.04 -12.61 9.15
Nuclear Periphery Foci -5.42 -13.65 -8.96 -8.29 9.81 -1.34 -10.71 -7.53 -3.19 8.39 -2.36 -17.24 -11.73 -8.46 13.08
Nucleolus -3.88 -8.59 -5.78 -2.41 7.03 -2.02 -5.92 -5.46 -3.44 2.06 -4.02 -10.38 -7.67 -4.15 6.94
Nucleus 4.13 -11.31 1.59 -1.74 11.30 6.89 -5.72 -1.06 -7.70 4.80 7.61 -11.59 1.07 -5.67 11.72
Peroxisomes -7.01 -0.87 -2.82 2.57 -2.01 -6.43 -4.23 -5.56 0.39 -1.49 -9.58 -4.63 -7.05 1.00 -2.80
Vacuole 0.24 -13.27 -24.13 -24.05 -14.95 0.74 -16.62 -27.00 -27.20 -11.75 0.81 -20.72 -35.46 -35.57 -18.55
Vacuole Periphery -4.16 2.17 -0.50 1.68 -1.18 -6.10 1.44 0.59 4.82 -0.44 -7.36 2.12 0.12 4.61 -1.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Lipid phosphate phosphatase; catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Lpp1

Lpp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Lpp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available