Standard name
Human Ortholog
Description High-affinity glutamine permease; also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids; GNP1 has a paralog, AGP1, that arose from the whole genome duplication
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 0.13 0 0.13 0.34 0.38 0.28 0.23 0.21 0.13 0.16 0.06 0.08 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.06 0.1 0.11 0.1 0.12 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.89 0.82 0.86 0.77 0.83 0.87 0.74 0.5 0.43 0.31 0.29 0.29 0.85 0.85 0.88 0.84 0.62 0.74 0.68 0.55 0.7 0.58 0.71 0.83
Cytoplasm 0.08 0.25 0.05 0.05 0.1 0.12 0.18 0.24 0.34 0.36 0.39 0.45 0.1 0.11 0.1 0.18 0.37 0.21 0 0.18 0 0.07 0 0
Endoplasmic Reticulum 0.12 0.1 0.13 0.24 0.11 0 0.09 0.24 0.22 0.21 0.21 0.13 0.21 0.23 0.13 0 0 0.06 0.26 0.22 0.22 0.25 0.15 0.05
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.08 0.12 0 0 0 0.06 0.07 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.08 0.12 0.16 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 12 37 9 41 108 175 146 88 94 56 82 12 24 9 4 7 0 1 6 4 1 4 4
Bud 2 5 2 4 5 11 29 51 41 44 52 44 4 3 3 7 2 2 0 1 1 1 4 7
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2
Bud Site 0 0 0 0 0 0 1 0 6 3 1 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 177 197 248 176 261 279 336 264 164 137 125 152 169 261 237 148 113 89 151 174 267 184 375 400
Cytoplasm 17 61 15 12 32 38 81 124 128 161 169 235 19 35 28 31 67 25 5 58 1 23 15 5
Endoplasmic Reticulum 25 25 38 55 36 13 39 127 84 96 91 67 41 69 35 5 5 7 58 69 83 80 77 26
Endosome 0 0 0 0 0 0 0 0 6 6 3 5 0 0 0 0 1 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 2 5 0 3 0 0 1 2 0 4 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 1 3 13 6 13 18 14 0 0 0 10 14 15 2 2 15 20 39 26
Nucleus 0 0 0 0 0 0 0 1 1 0 4 7 0 0 0 0 0 1 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 1 12 1 8 3 3 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 2 0 1 5 3 3 4 7 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 2 5 6 36 53 85 0 1 0 0 2 1 0 0 1 2 4 2
Unique Cell Count 200 240 287 229 314 319 456 525 381 449 430 528 198 306 268 177 182 121 223 317 380 319 528 483
Labelled Cell Count 229 300 340 256 377 450 668 750 536 608 581 707 245 393 313 207 211 144 223 317 380 319 528 483


Cell Periphery, Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 67.8 56.7 63.7 65.2 48.9 34.3 27.0 21.8 19.0 16.4 14.5 14.0 61.2 62.8 66.9 37.3 45.7 55.0 67.5 69.5 66.3
Std Deviation (1e-4) 15.1 12.9 14.7 12.6 11.9 9.3 8.6 7.5 7.8 7.2 6.6 6.2 13.4 16.5 14.0 10.0 14.3 19.0 13.4 16.5 16.7
Intensity Change (Log2) – – – 0.03 -0.38 -0.89 -1.24 -1.54 -1.74 -1.96 -2.14 -2.18 -0.06 -0.02 0.07 -0.77 -0.48 -0.21 0.08 0.12 0.06


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.5 0.1 6.0 7.5 4.9 3.3 2.8 0.1 1.0 -2.5 -2.0 -4.1 -3.9 -3.3 -4.1
Bud 0 0 2.3 3.8 5.0 5.2 5.0 5.7 4.5 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.8 -1.1 0.4 -4.1 -10.2 -11.4 -14.8 -15.1 -15.7 -0.3 -0.4 0.7 -0.8 -6.1 -3.1
Cytoplasm 0 2.3 2.9 5.0 6.7 8.8 9.5 10.2 11.6 1.9 2.7 2.3 4.3 8.8 4.8
Endoplasmic Reticulum 3.2 -0.7 -4.1 -2.0 3.7 2.9 2.8 2.7 -0.2 2.2 2.9 -0.1 -3.8 -3.8 -2.2
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 2.9 3.5 0 0 0 0 0 4.8 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 4.9 6.2 7.2 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 118.6286 138.79 129.6599 131.9131 74.5854 134.0688 115.6522 139.9555 136.6626 127.8223 101.9009 122.2285 131.6169 152.578 145.7363 140.4688 140.0306 146.7665
Actin 0.0028 0 0 0.0003 0.0205 0.0001 0.0051 0.0002 0.0001 0.0002 0.015 0.0002 0.0002 0 0 0 0 0
Bud 0.0003 0.0001 0 0.0001 0.0012 0.0002 0.0004 0 0.0005 0.0002 0.0006 0.0003 0.0001 0 0 0 0 0
Bud Neck 0.0006 0.0003 0.0006 0.0033 0.007 0.001 0.0009 0.0005 0.0014 0.0009 0.0029 0.0029 0.0002 0.0003 0.0005 0.0008 0.0009 0.0008
Bud Periphery 0.0019 0.0005 0.0003 0.0008 0.0041 0.0008 0.0034 0.0002 0.002 0.001 0.0039 0.0036 0.0004 0.0001 0.0002 0.0004 0.0007 0.0007
Bud Site 0.001 0.0054 0.0002 0.0003 0.0033 0.0002 0.0018 0.004 0.0004 0.0005 0.0075 0.0003 0.0002 0.0006 0.0002 0 0.0001 0
Cell Periphery 0.5372 0.6472 0.5883 0.6081 0.3678 0.5506 0.5184 0.6376 0.6097 0.5092 0.5339 0.5889 0.5121 0.6039 0.5615 0.5074 0.5187 0.5277
Cytoplasm 0.0038 0.0079 0.01 0.0014 0.0197 0.0044 0.0045 0.0064 0.0014 0.0006 0.0048 0.0025 0.0016 0.0016 0.001 0.0005 0.001 0.0007
Cytoplasmic Foci 0.0029 0 0.0039 0 0.0225 0.0008 0.0092 0.0001 0.0001 0.0002 0.0214 0.0028 0.0002 0 0 0 0 0
Eisosomes 0.0092 0.0055 0.0031 0.0034 0.0118 0.0126 0.0192 0.0076 0.006 0.0094 0.0038 0.0102 0.0101 0.0199 0.0084 0.0054 0.032 0.0064
Endoplasmic Reticulum 0.146 0.0987 0.1347 0.1158 0.1341 0.2136 0.1535 0.1106 0.1098 0.2061 0.1492 0.175 0.2129 0.1025 0.1524 0.2254 0.2436 0.2718
Endosome 0.0006 0 0 0 0.0232 0.0001 0.0019 0 0 0.0001 0.0054 0.0001 0 0 0 0 0 0
Golgi 0.0008 0 0 0.0001 0.0079 0.0001 0.001 0.0003 0 0.0001 0.0042 0.0002 0.0001 0 0 0 0 0.0001
Lipid Particles 0.0034 0.001 0.0018 0.0014 0.0608 0.0025 0.0077 0.0035 0.0006 0.0019 0.0235 0.0053 0.0023 0.0005 0.0006 0.0005 0.0006 0.0011
Mitochondria 0.0026 0 0.0002 0.0001 0.0307 0.0053 0.0059 0 0.0012 0.0227 0.017 0.0103 0.0002 0 0 0 0 0
None 0.0061 0 0.0009 0 0.0142 0.0026 0.0072 0 0.0029 0.001 0.0047 0.0005 0.0009 0 0 0 0 0.0001
Nuclear Periphery 0.2189 0.1988 0.2129 0.2165 0.1181 0.1574 0.2059 0.2062 0.2325 0.2108 0.1211 0.1512 0.2285 0.2477 0.2476 0.2293 0.1835 0.1629
Nucleolus 0.0098 0.0001 0.0015 0.0003 0.0543 0.0045 0.0063 0.0001 0.0004 0.0044 0.0165 0.0087 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Nucleus 0.0024 0.0005 0.0012 0.001 0.0096 0.001 0.0021 0.0006 0.0008 0.001 0.0023 0.0015 0.0004 0.0004 0.0004 0.0005 0.0004 0.0004
Peroxisomes 0.0008 0 0.0001 0 0.0255 0.0003 0.0059 0 0.0001 0.0004 0.0196 0.0007 0 0 0 0 0 0
Punctate Nuclear 0.0009 0 0.0006 0 0.0184 0 0.0019 0 0 0 0.0023 0.0001 0 0 0 0 0 0
Vacuole 0.0457 0.0337 0.039 0.0464 0.0407 0.0407 0.0352 0.0219 0.0293 0.0274 0.0385 0.0334 0.0289 0.0223 0.0265 0.0291 0.0181 0.0267
Vacuole Periphery 0.0021 0.0001 0.0004 0.0007 0.0047 0.0012 0.0023 0.0002 0.0006 0.0019 0.0018 0.0012 0.0006 0.0001 0.0004 0.0006 0.0003 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 137.3716 107.9468 123.0913 158.0525 140.0449 139.51 159.712 154.0892 178.1527 172.6892
Translational Efficiency 1.5522 1.5467 1.4055 1.2564 1.2085 1.6184 1.1951 1.0613 1.0952 1.1179

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
140 756 92 1062 1943 152 1528 1302 2083 908 1620 2364

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2525.68 4587.16 5785.90 4265.60 3923.28 4961.13 5395.67 4662.57 3829.35 4649.76 5417.83 4484.24
Standard Deviation 827.47 1130.67 688.43 980.09 824.27 1084.03 826.23 1040.18 895.68 1131.64 823.99 1032.68
Intensity Change Log 2 — 0.860929 1.195870 0.756077 — 0.338608 0.459742 0.249065 — 0.566176 0.793984 0.469298

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003259 0.000996 0.000253 0.001264 0.000133 0.001413 0.000798 0.002988 0.000343 0.001065 0.000767 0.002213
Bud Neck 0.008557 0.002273 0.002295 0.000795 0.000469 0.003421 0.000696 0.000630 0.001012 0.002465 0.000787 0.000704
Bud Site 0.017954 0.020260 0.002001 0.004321 0.002056 0.015110 0.003437 0.008602 0.003124 0.019398 0.003356 0.006679
Cell Periphery 0.443126* 0.682285* 0.666439* 0.725992* 0.708496* 0.734336* 0.595780* 0.859464* 0.690661* 0.690998* 0.599793* 0.799503*
Cytoplasm 0.011001 0.050172 0.000655 0.007350 0.017814 0.001501 0.023119 0.002360 0.017356 0.042025 0.021844 0.004601
Cytoplasmic Foci 0.013439 0.000561 0.000094 0.000217 0.000511 0.000434 0.000392 0.000555 0.001380 0.000539 0.000376 0.000403
Eisosomes 0.000859 0.002335 0.004980 0.002464 0.000539 0.005840 0.001252 0.000978 0.000561 0.002921 0.001464 0.001646
Endoplasmic Reticulum 0.127950* 0.011834 0.016788 0.015977 0.025640 0.026543 0.043810 0.006538 0.032517 0.014296 0.042276 0.010778
Endosome 0.014553 0.000846 0.000713 0.000587 0.000838 0.001186 0.000739 0.000549 0.001760 0.000903 0.000738 0.000566
Golgi 0.014906 0.005844 0.010414 0.003555 0.003379 0.010239 0.005361 0.004742 0.004154 0.006579 0.005648 0.004209
Lipid Particles 0.097294 0.026033 0.021836 0.004996 0.004718 0.012195 0.029465 0.004101 0.010940 0.023716 0.029032 0.004503
Mitochondria 0.000940 0.000767 0.000103 0.001088 0.000428 0.000764 0.000464 0.000475 0.000462 0.000767 0.000444 0.000750
Mitotic Spindle 0.007677 0.001440 0.001941 0.001528 0.001702 0.002341 0.002060 0.002005 0.002103 0.001591 0.002053 0.001791
None 0.000041 0.000332 0.000045 0.000173 0.000081 0.000117 0.000171 0.000048 0.000078 0.000296 0.000164 0.000104
Nuclear Periphery 0.014207 0.011963 0.019022 0.024542 0.034985 0.025175 0.063565 0.018373 0.033589 0.014175 0.061035 0.021144
Nuclear Periphery Foci 0.008763 0.004574 0.001678 0.001521 0.002383 0.001128 0.001780 0.000603 0.002811 0.003997 0.001774 0.001016
Nucleolus 0.000128 0.000239 0.000092 0.000212 0.000288 0.000159 0.000156 0.000142 0.000277 0.000226 0.000152 0.000173
Nucleus 0.000968 0.001210 0.000474 0.000696 0.000602 0.000397 0.000799 0.000282 0.000627 0.001074 0.000781 0.000468
Peroxisomes 0.000801 0.000698 0.000016 0.000161 0.000866 0.000082 0.001435 0.000277 0.000861 0.000595 0.001354 0.000225
Vacuole 0.207269* 0.159202 0.235032* 0.188686 0.178622 0.140000 0.212601* 0.075297 0.180547 0.155987 0.213875* 0.126236
Vacuole Periphery 0.006306 0.016138 0.015130 0.013874 0.015451 0.017620 0.012119 0.010992 0.014836 0.016386 0.012290 0.012287

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.35 3.04 1.95 -0.38 -1.66 -2.17 -2.17 -2.83 -1.33 -2.03 -3.20 -1.37 -2.94 -1.76 -2.03
Bud Neck 2.01 2.00 2.49 4.28 2.66 -1.45 -1.90 -1.26 1.31 -0.14 -2.96 0.91 1.00 3.77 0.19
Bud Site 0.48 3.66 3.26 5.06 -1.26 -1.89 -1.78 -3.72 0.89 -2.66 -5.86 -0.11 -2.64 4.34 -2.38
Cell Periphery -9.00 -7.51 -10.92 -3.95 -3.16 -1.44 15.71 -22.40 -7.33 -36.73* 0.01 12.44 -16.81 -11.75 -30.06*
Cytoplasm -5.44 3.66 1.84 7.92 -4.22 8.38 -1.68 7.95 -1.01 7.21 -5.24 -1.43 6.96 8.40 6.30
Cytoplasmic Foci 3.11 3.22 3.19 4.99 -2.68 0.34 3.00 -0.33 -0.48 -0.79 2.83 3.44 3.00 0.84 -0.33
Eisosomes -2.32 -2.77 -2.49 -0.14 1.56 -3.61 -4.58 -4.47 3.31 1.79 -4.05 -5.31 -3.68 1.98 -0.55
Endoplasmic Reticulum 6.16 5.57 5.92 -2.17 0.16 -0.15 -6.01 11.62 3.33 13.87 7.46 -3.18 10.30 2.17 12.09
Endosome 2.93 2.96 2.98 4.51 1.33 -1.50 2.30 3.44 2.54 2.32 2.59 3.13 3.62 4.66 3.37
Golgi 2.24 0.97 2.86 4.89 4.26 -4.58 -6.15 -2.25 3.45 0.96 -4.74 -3.72 -0.19 4.41 3.31
Lipid Particles 4.26 4.22 5.58 6.71 2.34 -1.45 -8.74 0.34 1.50 8.52 -4.28 -6.05 4.30 6.96 8.91
Mitochondria 0.26 1.40 -0.21 -0.62 -1.99 -1.09 -0.88 -0.78 0.83 -0.20 -2.57 0.04 -1.31 0.03 -1.32
Mitotic Spindle 1.81 1.66 1.78 -0.87 1.72 -3.35 -4.77 -1.71 0.78 -0.21 2.07 0.18 0.92 -1.70 1.42
None -5.80 -0.11 -1.40 1.52 -1.38 -0.89 -1.97 2.09 1.64 2.57 -5.11 -1.98 -0.64 3.27 1.16
Nuclear Periphery 0.80 -1.76 -4.76 -8.50 -2.09 2.66 -12.24 10.63 1.86 20.49 12.97 -12.37 8.96 -5.76 19.58
Nuclear Periphery Foci 2.48 4.18 4.30 5.46 0.51 6.20 3.75 12.62 3.21 10.91 -2.46 5.44 9.47 6.50 6.27
Nucleolus -1.30 0.37 -0.98 1.21 -4.96 5.51 14.23 12.14 0.61 0.98 3.78 11.77 7.51 3.56 -1.98
Nucleus 0.44 2.01 1.39 1.78 -0.77 1.83 -2.71 4.93 0.92 6.13 -3.29 -1.81 1.30 3.55 2.36
Peroxisomes 0.27 3.01 2.44 2.36 -6.69 10.90 -3.11 5.87 -2.71 6.31 1.35 -2.85 8.04 1.91 6.86
Vacuole 3.04 -0.82 1.48 -3.91 2.97 3.66 -6.54 23.25 6.24 28.88 4.14 -6.42 12.05 5.27 18.36
Vacuole Periphery -6.54 -2.36 -5.89 1.94 0.33 -0.97 5.49 7.81 2.91 1.88 -1.58 4.14 4.80 4.25 -0.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description High-affinity glutamine permease; also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids; GNP1 has a paralog, AGP1, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (24%), cytoplasm (2%), mixed (61%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Gnp1

Gnp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gnp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available