Standard name
Human Ortholog
Description Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0 0 0
Bud 0 0 – 0 0 0 0 0 0 0 0 0.08 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0.06 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.86 0.96 – 0.97 0.97 0.89 0.89 0.89 0.84 0.69 0.55 0.62 0.99 0.99 0.99 – 0.94 0.93 0.6 0.84 0.54 0.85 0.88 0.79
Endoplasmic Reticulum 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0.1 0.07 0 0 0 0 0 0
Endosome 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0 0 0
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0.36 0.05 – 0.16 0.05 0.22 0.22 0.2 0.38 0.43 0.6 0.5 0 0 0 – 0.05 0 0.2 0.05 0.21 0.05 0 0.08
Nucleus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 – 0 0 0 0 0 0 0 0 0.08 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0.07 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 1 1 2 0 1 4
Bud 0 0 – 0 0 0 0 2 2 2 1 2 0 0 0 – 0 0 1 1 0 0 0 3
Bud Neck 0 0 – 0 0 1 0 7 0 1 3 0 0 0 0 – 1 2 0 1 0 0 0 2
Bud Site 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 1 1 – 0 0 0 1 1 1 0 0 0 1 0 1 – 3 5 0 0 0 0 1 0
Cytoplasm 104 172 – 31 37 16 93 171 46 47 49 16 168 242 308 – 197 149 79 148 20 80 197 163
Endoplasmic Reticulum 1 1 – 0 0 0 1 0 0 0 0 0 0 1 0 – 21 12 1 1 0 0 0 1
Endosome 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 – 2 3 2 1 2 0 1 2
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 1 0 1 – 2 1 1 0 0 0 1 0
Mitochondria 43 9 – 5 2 4 23 39 21 29 53 13 1 0 1 – 11 6 26 9 7 4 9 15
Nucleus 0 0 – 0 0 0 0 2 0 0 0 0 0 1 0 – 0 2 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0
Nucleolus 0 0 – 0 0 0 1 0 0 1 0 0 0 0 0 – 1 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0
SpindlePole 0 0 – 0 0 0 1 5 0 1 4 2 0 0 0 – 0 2 4 2 0 0 1 1
Vac/Vac Membrane 1 1 – 0 0 0 0 0 1 1 0 0 0 0 0 – 7 2 9 3 0 1 2 5
Unique Cell Count 121 179 32 38 18 104 193 55 68 89 26 170 244 310 209 161 132 178 38 95 225 208
Labelled Cell Count 150 184 36 39 21 120 229 71 82 110 33 171 244 311 245 185 132 178 38 95 225 208


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 3.6 – 3.1 3.9 2.7 2.6 3.3 2.8 2.5 2.5 2.4 4.2 4.0 4.1 4.8 5.4 5.5 3.5 3.9 4.7
Std Deviation (1e-4) 0.6 1.4 – 1.6 2.0 0.9 1.8 2.4 1.6 1.2 1.3 0.9 1.4 1.5 1.4 1.8 2.1 1.9 1.0 1.4 1.3
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.771 0.4456 0.4665 0.0217 0.7138 0.2835 0.7242 0.8446 0.8644 0.704 0.9036 1.0647 1.2095 1.1885 1.2588 0.8249 0.7329 1.1206
Actin 0.0654 0.0013 0.02 0.001 0.0039 0.0027 0.02 0 0.0045 0.0163 0.0022 0.0088 0.0671 0.0001 0.0264 0.0217 0 0.006
Bud 0.0028 0.0042 0.0067 0.0004 0.003 0.0006 0.0005 0.0003 0.0017 0.001 0.0005 0.004 0.0018 0.0002 0.0031 0.0012 0 0.0001
Bud Neck 0.0098 0.0001 0.0007 0.0001 0.0013 0.0011 0.0033 0 0.0003 0.0002 0.0002 0.0003 0.001 0.0001 0.0031 0.0167 0 0.0071
Bud Periphery 0.0095 0.0071 0.0119 0.0009 0.0138 0.0013 0.0014 0.0015 0.0007 0.0027 0.0006 0.0018 0.0052 0.0003 0.0057 0.0039 0 0.0005
Bud Site 0.0189 0.0098 0.006 0.0003 0.0062 0.0005 0.0054 0.0005 0.0021 0.001 0.0007 0.0003 0.0062 0.001 0.0157 0.0214 0 0.0001
Cell Periphery 0.0013 0.0003 0.0004 0.0001 0.0004 0.0001 0.0007 0.0001 0.0003 0.0003 0.0001 0.0001 0.001 0.0001 0.0026 0.0036 0 0.0001
Cytoplasm 0.0318 0.0286 0.041 0.0306 0.0802 0.0794 0.0099 0.0111 0.0233 0.0105 0.0188 0.0251 0.0208 0.0274 0.023 0.0257 0.0333 0.0334
Cytoplasmic Foci 0.0158 0.0042 0.0088 0.0238 0.0358 0.0176 0.0064 0.001 0.0134 0.0211 0.0044 0.0083 0.0119 0.0112 0.0071 0.0031 0.0099 0.0015
Eisosomes 0.0006 0.0001 0.0003 0.0002 0.0002 0.0001 0.0013 0.0002 0.0005 0.0004 0.0001 0.0002 0.0016 0.0002 0.0011 0.0004 0.0001 0.0001
Endoplasmic Reticulum 0.0032 0.001 0.0029 0.0006 0.0036 0.0007 0.0039 0.0001 0.0006 0.0006 0.0003 0.0003 0.0044 0.0003 0.0027 0.0011 0.0002 0.0002
Endosome 0.0129 0.0007 0.0091 0.0043 0.0499 0.0069 0.0157 0.0001 0.0024 0.006 0.0239 0.0084 0.0127 0.0024 0.0021 0.0035 0.0003 0.0001
Golgi 0.0104 0.0008 0.0059 0.0027 0.0127 0.0062 0.0051 0 0.0008 0.0041 0.0171 0.011 0.0063 0.0002 0.001 0.0012 0 0.0002
Lipid Particles 0.0097 0.002 0.0036 0.0188 0.0172 0.0044 0.0056 0.0001 0.003 0.0058 0.0013 0.0073 0.0093 0.0007 0.0015 0.0016 0.0001 0.0001
Mitochondria 0.0059 0.001 0.0082 0.001 0.0767 0.0043 0.0164 0.0003 0.0006 0.0177 0.0505 0.0132 0.0108 0.0003 0.0016 0.0011 0.0001 0.0002
None 0.7528 0.9272 0.8558 0.9044 0.6523 0.8626 0.8965 0.9841 0.9295 0.9076 0.8753 0.898 0.8004 0.9532 0.8715 0.8832 0.9514 0.9494
Nuclear Periphery 0.0094 0.0004 0.0047 0.0003 0.0072 0.0032 0.0027 0 0.0002 0.0006 0.0001 0.0002 0.008 0.0002 0.0052 0.0005 0.0001 0.0001
Nucleolus 0.0014 0.0004 0.0003 0.0002 0.0005 0.001 0.0005 0.0001 0.0002 0.0001 0.0001 0.0002 0.0013 0.0003 0.002 0.0009 0.0002 0
Nucleus 0.0085 0.0017 0.0067 0.0004 0.0055 0.0009 0.0006 0.0001 0.0004 0.0002 0.0001 0.0009 0.0023 0.0004 0.0048 0.0009 0.0003 0.0001
Peroxisomes 0.0161 0.0069 0.0035 0.0077 0.0103 0.0017 0.0015 0.0001 0.0145 0.0014 0.0011 0.0105 0.0197 0.0005 0.0122 0.0007 0.0001 0.0001
Punctate Nuclear 0.0035 0.0014 0.0013 0.0016 0.0014 0.0031 0.0008 0.0001 0.0005 0.0009 0.0001 0.0006 0.0053 0.0007 0.0067 0.0005 0.0038 0.0002
Vacuole 0.0065 0.0006 0.0013 0.0005 0.0132 0.001 0.001 0.0002 0.0005 0.0009 0.0015 0.0004 0.0018 0.0004 0.0006 0.0067 0.0001 0.0001
Vacuole Periphery 0.0039 0.0001 0.0007 0.0001 0.0049 0.0005 0.0007 0 0.0001 0.0007 0.001 0.0002 0.0013 0 0.0002 0.0005 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 0.3745 3.3482 1.9876 1.1104 1.4568 3.7434 1.3541 0.6855 1.9083 0.9558
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
727 1357 1532 1347 1451 1488 181 938 2178 2845 1713 2285

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 641.93 673.63 787.37 816.98 684.16 699.68 947.08 782.79 670.06 687.25 804.25 802.94
Standard Deviation 58.62 105.44 89.56 117.81 73.30 86.82 93.85 126.83 71.58 97.03 102.54 122.76
Intensity Change Log 2 — 0.069540 0.294626 0.347885 — 0.032361 0.469153 0.194292 — 0.050479 0.387300 0.270686

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000103 0.000312 0.000137 0.002463 0.000083 0.000797 0.000262 0.000729 0.000090 0.000566 0.000150 0.001751
Bud Neck 0.031910 0.041959 0.004131 0.007421 0.014636 0.064970 0.000969 0.008165 0.020402 0.053994 0.003797 0.007727
Bud Site 0.008472 0.013880 0.007933 0.049378 0.002009 0.023709 0.001617 0.028209 0.004166 0.019021 0.007265 0.040688
Cell Periphery 0.000159 0.000132 0.000109 0.000215 0.000098 0.000234 0.000196 0.000515 0.000119 0.000185 0.000118 0.000338
Cytoplasm 0.522715* 0.397472* 0.337696* 0.421422* 0.514426* 0.305704* 0.280321* 0.452529* 0.517193* 0.349475* 0.331634* 0.434191*
Cytoplasmic Foci 0.153226 0.234832* 0.009803 0.026051 0.201487* 0.324590* 0.027699 0.034754 0.185378* 0.281777* 0.011694 0.029623
Eisosomes 0.000188 0.000135 0.000027 0.000054 0.000151 0.000292 0.000122 0.000069 0.000163 0.000217 0.000037 0.000060
Endoplasmic Reticulum 0.000570 0.000775 0.001615 0.002401 0.000367 0.000445 0.004040 0.001087 0.000435 0.000602 0.001872 0.001861
Endosome 0.006345 0.028841 0.001639 0.014664 0.005745 0.036903 0.006914 0.015954 0.005945 0.033058 0.002196 0.015193
Golgi 0.002715 0.004576 0.000074 0.011161 0.001487 0.013284 0.000088 0.008298 0.001897 0.009130 0.000076 0.009986
Lipid Particles 0.005778 0.008413 0.000969 0.001481 0.005546 0.008386 0.004068 0.001801 0.005623 0.008399 0.001297 0.001613
Mitochondria 0.005005 0.014089 0.000458 0.004345 0.002249 0.024838 0.000232 0.009483 0.003169 0.019711 0.000434 0.006454
Mitotic Spindle 0.002475 0.004978 0.001487 0.067814 0.000742 0.013290 0.000135 0.030982 0.001320 0.009325 0.001344 0.052694
None 0.005228 0.004668 0.006100 0.007009 0.002206 0.001747 0.002479 0.021282 0.003215 0.003140 0.005718 0.012868
Nuclear Periphery 0.000331 0.000584 0.001404 0.001637 0.000338 0.000300 0.001866 0.001183 0.000336 0.000435 0.001452 0.001451
Nuclear Periphery Foci 0.000266 0.000485 0.000475 0.001645 0.000315 0.000283 0.003348 0.001299 0.000299 0.000379 0.000779 0.001503
Nucleolus 0.001192 0.003352 0.000487 0.000742 0.000713 0.001330 0.000562 0.000956 0.000873 0.002294 0.000495 0.000830
Nucleus 0.206850* 0.126783 0.596846* 0.257226* 0.210249* 0.068124 0.472182* 0.266624* 0.209115* 0.096103 0.583674* 0.261084*
Peroxisomes 0.002947 0.016615 0.000510 0.003702 0.003613 0.038082 0.000404 0.003533 0.003391 0.027843 0.000499 0.003633
Vacuole 0.042788 0.094096 0.027881 0.112553 0.033092 0.069803 0.192291 0.104426 0.036328 0.081390 0.045253 0.109217
Vacuole Periphery 0.000737 0.003024 0.000218 0.006615 0.000448 0.002890 0.000204 0.008122 0.000544 0.002954 0.000216 0.007234

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.56 -2.27 -2.43 -1.83 -2.26 -5.24 -5.56 -5.01 1.37 -2.19 -6.62 -3.75 -3.33 -1.08 -2.88
Bud Neck -2.29 8.26 7.96 13.69 -1.81 -13.54 8.75 4.31 16.51 -5.38 -12.65 9.86 8.97 21.47 -2.57
Bud Site -2.93 0.62 -4.80 -3.13 -5.19 -12.23 -0.70 -6.87 1.33 -6.77 -12.60 -2.09 -9.00 -1.11 -6.55
Cell Periphery 2.19 3.40 1.86 -0.40 -2.22 -5.06 -6.25 -4.04 -1.53 -2.22 -4.17 0.03 -3.83 -1.09 -3.80
Cytoplasm 11.01 19.01 17.82 7.05 -0.33 21.60 17.03 11.65 -6.47 -8.23 22.64 25.98 21.94 0.52 -4.41
Cytoplasmic Foci -9.28 22.13 21.15 36.44 -4.41 -14.90 30.27 31.30 46.56 -0.81 -15.77 40.87 38.52 58.48 -7.45
Eisosomes 4.03 12.74 9.74 11.57 -13.54 -6.20 0.37 6.15 11.01 7.00 -3.89 13.04 10.14 13.58 -10.48
Endoplasmic Reticulum -2.44 -12.48 -14.57 -13.66 -6.23 -1.06 -10.82 -12.74 -12.02 7.02 -3.15 -17.92 -19.09 -17.69 -2.43
Endosome -11.53 6.07 0.72 11.68 -4.36 -16.21 -1.63 -2.11 12.57 -1.03 -19.92 8.47 -1.06 17.64 -5.95
Golgi -2.32 5.61 -0.38 1.20 -3.24 -9.99 5.25 -2.11 6.08 -3.51 -10.14 7.69 -2.01 5.83 -4.72
Lipid Particles -2.89 8.27 7.48 9.56 -3.46 -3.84 2.07 7.34 11.48 5.94 -4.74 10.81 10.35 14.90 -1.38
Mitochondria -5.70 7.72 4.98 8.33 -4.03 -11.39 6.71 -1.61 8.20 -3.02 -12.97 9.58 0.35 12.00 -3.92
Mitotic Spindle -1.36 0.35 -8.09 -7.52 -8.69 -5.55 0.77 -6.90 -3.10 -7.14 -5.62 -0.63 -10.95 -7.39 -10.92
None 0.60 -0.18 0.93 0.17 1.07 1.08 0.93 -4.95 -5.12 -5.09 0.14 -3.02 -4.73 -4.51 -2.60
Nuclear Periphery -2.67 -15.82 -16.28 -14.90 -8.29 0.36 -14.27 -14.53 -12.39 0.62 -1.65 -23.90 -21.63 -19.15 -7.76
Nuclear Periphery Foci -2.06 -3.69 -5.50 -4.64 -4.15 0.15 -6.35 -3.57 -4.43 4.52 -0.77 -5.04 -6.03 -6.41 -2.85
Nucleolus -5.34 5.14 3.34 6.72 -0.87 -4.44 2.72 -1.05 3.43 -3.67 -6.92 4.86 1.56 7.56 -2.45
Nucleus 10.26 -41.63 -10.13 -20.33 28.87 25.82 -9.58 -10.44 -26.75 4.52 24.38 -47.18 -14.63 -33.80 30.71
Peroxisomes -11.58 7.30 3.99 12.91 -2.16 -15.85 9.40 2.42 16.14 -2.20 -19.01 9.86 4.65 20.21 -2.82
Vacuole -11.85 0.38 -27.26 -19.85 -27.84 -11.17 -12.88 -19.81 -14.14 5.14 -17.14 -8.30 -34.20 -24.79 -25.12
Vacuole Periphery -6.31 5.51 -1.74 1.28 -2.51 -4.46 3.65 -3.12 -0.77 -3.35 -7.17 5.52 -3.60 0.28 -4.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis
Localization
Cell Percentages cytoplasm (19%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Sps1

Sps1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sps1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available