Standard name
Human Ortholog
Description Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase; catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA); transcriptionally regulated by Upc2p via a sterol response element
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.96 0.99 0.98 0.87 0.86 0.85 0.71 0.73 0.7 0.71 0.6 0.64 0.98 0.97 0.96 0.88 0.89 0.96 0.92 0.93 0.91 0.96 0.94 0.95
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.19 0.09 0.25 0.16 0.38 0.21 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.18 0.18 0.12 0.17 0.18 0.12 0.18 0.15 0.18 0 0 0.06 0.13 0.09 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0
Bud 0 0 0 0 0 2 7 4 7 4 12 13 0 0 0 0 0 0 1 1 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 0 2 1 9 2 5 6 4 8 4 10 3 1 1 9 11 5 0 0 0 0 0 0
Cytoplasm 192 277 279 327 528 418 401 486 302 346 203 294 320 428 468 257 203 145 183 260 260 271 472 410
Endoplasmic Reticulum 2 3 2 0 2 4 1 4 3 2 0 3 3 4 2 8 7 7 1 1 1 1 6 5
Endosome 0 0 0 1 1 0 0 0 0 1 0 1 0 0 0 1 1 0 0 1 2 0 1 0
Golgi 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 0 0 1 0 0
Mitochondria 3 0 0 2 6 23 105 60 106 76 128 98 0 0 0 1 3 1 0 2 6 0 5 0
Nucleus 6 3 2 3 6 14 20 27 12 18 10 18 2 0 3 8 5 1 4 3 4 2 3 1
Nuclear Periphery 0 0 0 0 0 1 3 4 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0
Vac/Vac Membrane 0 0 4 69 112 58 98 117 51 87 52 85 5 14 29 39 21 4 5 3 2 1 2 3
Unique Cell Count 200 279 284 378 616 491 565 665 429 490 338 460 325 441 485 293 227 151 199 280 286 282 504 430
Labelled Cell Count 205 284 290 404 664 522 642 710 487 543 409 524 333 447 503 326 252 164 199 280 286 282 504 430


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.9 12.6 10.2 9.7 9.5 7.5 6.5 7.2 6.1 6.3 5.6 6.1 10.6 10.7 10.5 14.4 15.2 14.8 9.9 11.1 11.3
Std Deviation (1e-4) 1.3 2.1 1.6 1.6 1.6 1.3 1.4 1.3 1.3 1.1 1.4 1.2 1.6 1.6 1.5 3.0 3.1 3.0 1.7 1.9 2.0
Intensity Change (Log2) – – – -0.08 -0.11 -0.45 -0.65 -0.51 -0.74 -0.7 -0.88 -0.75 0.05 0.06 0.03 0.49 0.57 0.53 -0.05 0.12 0.15

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 3.2 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 2.1 3.0 0
Cytoplasm -5.4 -5.7 -5.8 -9.4 -9.0 -9.4 -9.4 -11.4 -10.8 0.2 -1.0 -1.4 -4.9 -4.3 -1.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.7 7.8 5.2 9.1 7.0 11.6 8.3 0 0 0 0 0 0
Nucleus 0 0 2.0 2.5 2.8 2.0 2.5 2.0 2.6 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 6.8 7.0 5.1 6.7 6.8 5.1 6.8 6.1 7.0 0 1.5 3.0 5.4 4.1 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.3916 10.8574 9.3678 9.1852 7.7167 9.0457 7.3148 11.5817 9.3809 8.1195 7.6584 8.4432 7.2234 9.5511 8.7391 7.1038 7.0592 8.3706
Actin 0.0303 0.0002 0.0282 0.0122 0.03 0.019 0.0147 0.0005 0.0178 0.0208 0.0103 0.0033 0.0133 0.0008 0.0053 0.0026 0.005 0.0027
Bud 0.0006 0.0001 0.0015 0.0002 0.0003 0.0001 0.0004 0.0021 0.0006 0.0006 0.0013 0.0003 0.0005 0.0002 0.0001 0.0001 0.0025 0.0007
Bud Neck 0.0006 0.0002 0.0006 0.0016 0.0016 0.0012 0.0008 0.0004 0.0008 0.0012 0.0023 0.0019 0.0006 0.0002 0.0004 0.0004 0.0012 0.001
Bud Periphery 0.0006 0 0.0016 0.0001 0.0002 0 0.0004 0.0012 0.0003 0.0004 0.001 0.0002 0.0008 0.0001 0.0001 0 0.0014 0.0006
Bud Site 0.0017 0.0002 0.0047 0.0006 0.001 0.0001 0.0013 0.0034 0.0012 0.0037 0.0013 0.0001 0.0023 0.0013 0.0003 0.0001 0.001 0.0002
Cell Periphery 0.0002 0 0.0001 0 0.0001 0 0.0001 0.0001 0 0.0001 0.0001 0 0.0007 0 0 0 0.0001 0
Cytoplasm 0.772 0.9731 0.872 0.8963 0.8386 0.9008 0.8332 0.9573 0.9086 0.7866 0.7846 0.9048 0.8085 0.9516 0.9286 0.867 0.7586 0.9282
Cytoplasmic Foci 0.0215 0.0011 0.0134 0.0189 0.0187 0.0108 0.0236 0.0025 0.0102 0.0312 0.0213 0.007 0.023 0.0041 0.0116 0.0239 0.0343 0.004
Eisosomes 0.0003 0 0.0001 0.0002 0.0002 0 0.0001 0 0.0001 0.0001 0.0001 0 0.001 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0078 0.001 0.0014 0.0021 0.0012 0.0021 0.0068 0.0011 0.0018 0.0027 0.0016 0.0028 0.0067 0.0012 0.001 0.0011 0.0025 0.0012
Endosome 0.05 0.0005 0.0105 0.0101 0.0158 0.0105 0.0356 0.0043 0.0067 0.0494 0.0321 0.0145 0.0328 0.0027 0.0027 0.0125 0.0584 0.0032
Golgi 0.0097 0 0.0101 0.0018 0.0345 0.0013 0.0047 0.0006 0.0044 0.0245 0.0332 0.0039 0.0111 0.0006 0.003 0.0059 0.0297 0.0021
Lipid Particles 0.0105 0 0.0058 0.0036 0.0221 0.0004 0.0033 0.0001 0.0007 0.0084 0.0227 0.0009 0.0135 0.0003 0.0041 0.031 0.0068 0.0006
Mitochondria 0.0054 0.0001 0.0184 0.0008 0.0094 0.0005 0.004 0.0009 0.0014 0.01 0.0436 0.0013 0.0228 0.0002 0.0066 0.0024 0.0506 0.0025
None 0.0221 0.0037 0.0022 0.0067 0.0016 0.0018 0.0072 0.0022 0.0021 0.0015 0.0035 0.0019 0.0116 0.0031 0.0014 0.0015 0.0031 0.0021
Nuclear Periphery 0.0086 0.0021 0.0022 0.0024 0.002 0.0031 0.013 0.003 0.0056 0.0043 0.003 0.0044 0.0069 0.002 0.0022 0.0019 0.0032 0.0027
Nucleolus 0.0005 0 0.0001 0.0001 0 0 0.0003 0.0001 0.0001 0.0002 0.0002 0.0001 0.0003 0 0 0.0001 0.0003 0.0001
Nucleus 0.0159 0.017 0.0179 0.0255 0.0099 0.045 0.0383 0.0178 0.0319 0.0385 0.0205 0.0392 0.0268 0.0296 0.0208 0.0231 0.0151 0.0453
Peroxisomes 0.0041 0 0.007 0.0125 0.0111 0.0009 0.002 0.0002 0.0033 0.0118 0.012 0.0007 0.0083 0.0007 0.0103 0.0245 0.0123 0.0008
Punctate Nuclear 0.0211 0.0003 0.0011 0.0027 0.0007 0.0012 0.0037 0.0009 0.0012 0.0011 0.0027 0.0086 0.0039 0.001 0.0009 0.001 0.0085 0.0012
Vacuole 0.0135 0.0003 0.0007 0.0012 0.0007 0.0007 0.0045 0.0013 0.001 0.0019 0.0017 0.003 0.0035 0.0004 0.0004 0.0006 0.0032 0.0006
Vacuole Periphery 0.0031 0.0001 0.0003 0.0003 0.0004 0.0002 0.0019 0.0003 0.0003 0.0009 0.0009 0.001 0.0013 0.0001 0.0001 0.0002 0.002 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 45.4755 25.9102 33.8122 48.8921 29.8044 31.965 44.9428 37.4975 38.3511 51.1171
Translational Efficiency 0.7706 1.0339 0.7976 0.5722 0.9373 1.2931 0.7566 0.9307 0.9198 0.767

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
97 981 2076 1348 1806 2246 248 957 1903 3227 2324 2305

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1015.52 1304.16 1198.01 1092.72 1052.45 1182.64 1205.70 1017.16 1050.57 1219.58 1198.83 1061.35
Standard Deviation 145.68 219.71 169.08 145.41 156.87 180.78 150.19 208.13 156.53 201.36 167.18 178.15
Intensity Change Log 2 — 0.360902 0.238421 0.105705 — 0.168259 0.196119 -0.049205 — 0.266075 0.217048 0.028946

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001420 0.000214 0.000348 0.000826 0.000107 0.000257 0.000625 0.001089 0.000174 0.000244 0.000378 0.000935
Bud Neck 0.011646 0.000842 0.002554 0.005505 0.000659 0.002152 0.003344 0.012513 0.001220 0.001754 0.002638 0.008415
Bud Site 0.064687 0.004007 0.006341 0.027141 0.002306 0.005798 0.009600 0.034424 0.005486 0.005253 0.006689 0.030165
Cell Periphery 0.000384 0.000072 0.000072 0.000140 0.000048 0.000042 0.000230 0.000346 0.000065 0.000051 0.000089 0.000226
Cytoplasm 0.472117 0.803695 0.553151 0.584052 0.805542 0.805209 0.432106 0.450313 0.788547 0.804749 0.540234 0.528526
Cytoplasmic Foci 0.120505 0.023435 0.002985 0.016106 0.034547 0.020913 0.020988 0.036703 0.038928 0.021680 0.004906 0.024657
Eisosomes 0.000067 0.000006 0.000007 0.000019 0.000007 0.000007 0.000067 0.000094 0.000010 0.000007 0.000013 0.000050
Endoplasmic Reticulum 0.020245 0.000638 0.000756 0.002120 0.000963 0.000516 0.007247 0.001798 0.001946 0.000553 0.001449 0.001986
Endosome 0.012433 0.001644 0.000316 0.007281 0.001211 0.002822 0.006609 0.027342 0.001783 0.002464 0.000988 0.015610
Golgi 0.002422 0.001143 0.000056 0.006766 0.000276 0.001355 0.000185 0.011258 0.000386 0.001291 0.000070 0.008631
Lipid Particles 0.005702 0.000618 0.000319 0.002177 0.000479 0.000404 0.002054 0.005703 0.000745 0.000469 0.000504 0.003641
Mitochondria 0.008082 0.000497 0.000474 0.001615 0.000460 0.000924 0.000401 0.009254 0.000848 0.000794 0.000466 0.004787
Mitotic Spindle 0.030058 0.010880 0.005352 0.045984 0.004493 0.007101 0.001377 0.031648 0.005796 0.008250 0.004928 0.040032
None 0.001515 0.008519 0.008905 0.006838 0.005071 0.005799 0.005815 0.011778 0.004890 0.006626 0.008575 0.008889
Nuclear Periphery 0.002742 0.000165 0.000745 0.001154 0.000211 0.000281 0.001284 0.000666 0.000340 0.000246 0.000803 0.000951
Nuclear Periphery Foci 0.016010 0.003680 0.000904 0.003498 0.002545 0.001256 0.008358 0.001639 0.003232 0.001993 0.001699 0.002726
Nucleolus 0.005447 0.000316 0.000138 0.000360 0.000306 0.000651 0.000364 0.000922 0.000568 0.000549 0.000162 0.000593
Nucleus 0.094569 0.114976 0.394926 0.170067 0.118382 0.103121 0.230597 0.182256 0.117168 0.106725 0.377390 0.175128
Peroxisomes 0.003308 0.000431 0.000162 0.000637 0.000125 0.000575 0.000381 0.007409 0.000287 0.000532 0.000185 0.003449
Vacuole 0.120914 0.023554 0.021435 0.107297 0.021609 0.039562 0.267442 0.164347 0.026671 0.034695 0.047687 0.130983
Vacuole Periphery 0.005726 0.000669 0.000055 0.010415 0.000653 0.001254 0.000924 0.008498 0.000911 0.001076 0.000148 0.009619

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 4.22 3.30 3.27 -4.64 -0.44 -1.98 -3.78 -4.22 -2.85 1.09 -1.33 -3.57 -6.14 -4.23 -0.54
Bud Neck 2.38 1.86 1.65 -10.24 -2.11 -4.10 -8.62 -5.37 -3.98 -2.83 -1.69 -5.49 -7.24 -6.23 -3.47
Bud Site 3.84 3.72 3.32 -5.16 -3.52 -3.21 -4.68 -6.84 -5.48 -3.75 0.38 -0.65 -5.99 -7.07 -5.55
Cell Periphery 3.09 2.95 2.86 -2.72 -1.14 1.36 -11.34 -7.85 -8.02 1.93 1.82 -5.35 -7.25 -9.40 -2.90
Cytoplasm -9.45 -0.66 0.64 35.41 4.94 3.70 28.13 37.43 34.62 -5.01 0.80 46.92 48.32 51.11 4.56
Cytoplasmic Foci 6.18 7.67 7.35 8.93 -6.79 7.22 9.37 7.29 0.88 -2.51 8.59 19.77 14.06 7.87 -10.68
Eisosomes 7.61 7.12 5.15 -16.16 -12.74 -1.06 -13.46 -14.07 -13.72 3.73 3.29 -6.80 -17.09 -19.37 -11.15
Endoplasmic Reticulum 2.99 2.91 2.83 -7.04 -4.07 4.02 -6.33 -1.70 -4.37 5.79 3.90 0.62 1.08 -9.08 1.10
Endosome 4.18 4.67 3.96 -1.18 -5.11 -2.97 -6.67 -5.20 -4.31 -2.96 -1.20 4.29 -4.83 -4.02 -6.14
Golgi 1.33 2.40 1.14 -0.28 -2.40 -3.16 1.78 -3.57 -2.62 -3.65 -3.10 4.74 -3.82 -2.18 -4.45
Lipid Particles 3.28 3.33 2.62 -3.63 -5.22 0.65 -10.89 -3.56 -3.64 -0.91 1.95 -0.69 -4.49 -5.34 -4.44
Mitochondria 1.91 1.86 1.83 -1.01 -1.12 -1.21 0.41 -3.51 -3.15 -3.81 0.33 0.71 -2.23 -3.08 -3.66
Mitotic Spindle 1.24 1.46 0.03 -4.80 -6.93 -1.64 0.79 -7.73 -7.09 -8.17 -1.39 -0.67 -9.56 -9.08 -9.94
None -5.79 -10.12 -6.56 1.24 3.84 -0.76 1.02 -2.55 -2.29 -2.83 -2.65 -8.11 -3.68 -1.83 0.80
Nuclear Periphery 2.42 1.31 0.53 -25.05 -9.34 -2.59 -14.88 -15.10 -12.92 3.57 0.76 -15.25 -19.12 -25.65 -6.63
Nuclear Periphery Foci 1.98 2.50 2.24 2.68 -6.28 5.56 -5.59 2.55 -2.90 6.34 2.81 3.44 2.34 -0.98 -2.11
Nucleolus 1.51 1.55 1.49 -0.72 -4.87 -1.81 -0.02 -2.14 0.15 -3.08 0.12 1.83 0.43 0.54 -6.21
Nucleus -1.93 -21.06 -6.98 -12.71 31.87 2.37 -9.72 -6.65 -8.21 6.47 1.00 -52.14 -14.80 -16.83 36.41
Peroxisomes 3.10 3.39 3.31 1.13 -1.13 -3.74 -1.57 -3.40 -2.87 -2.87 -2.02 1.31 -3.05 -2.40 -3.34
Vacuole 5.23 4.74 -6.79 -29.91 -29.39 -12.03 -17.84 -27.97 -23.66 2.80 -8.61 -13.00 -41.36 -37.14 -29.98
Vacuole Periphery 1.70 1.88 1.26 -1.49 -2.34 -1.19 0.94 -2.65 -2.13 -2.99 -0.06 3.06 -2.25 -2.28 -3.93
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase; catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA); transcriptionally regulated by Upc2p via a sterol response element
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Cab1

Cab1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cab1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available