Standard name
Human Ortholog
Description Subunit of the heterohexameric cochaperone prefoldin complex; complex binds specifically to cytosolic chaperonin and transfers target proteins to it
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.2 – 0.21 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.99 0.97 0.96 0.87 – 0.73 0.69 0.67 0.66 0.63 0.98 0.99 0.99 0.83 – 0.91 0.97 0.97 0.92 0.94 0.91 0.94
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.17 0.08 0.32 – 0.48 0.59 0.53 0.61 0.55 0 0 0 0 – 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0.05 0.05 0 0 0 0 0 0 0.22 – 0.19 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 2 1 – 0 0 0 2 1 1 1 1 0 – 0 2 0 2 0 0 1
Bud 3 1 12 2 2 4 – 13 4 7 12 7 2 2 1 0 – 0 2 0 0 0 0 1
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 13 8 4 6 7 5 – 9 10 7 15 19 34 21 48 29 – 22 0 0 0 0 0 0
Cytoplasm 810 198 310 232 365 377 – 335 325 318 255 291 795 574 917 123 – 95 808 197 293 488 459 489
Endoplasmic Reticulum 3 2 4 1 4 1 – 1 2 10 4 24 12 3 2 4 – 3 0 0 5 10 12 8
Endosome 0 0 0 0 0 0 – 2 1 0 1 0 0 0 2 2 – 0 3 2 0 2 3 3
Golgi 1 1 0 0 0 0 – 0 0 0 0 0 1 0 0 0 – 1 3 1 1 3 5 3
Mitochondria 6 1 8 40 30 138 – 220 279 252 234 252 2 0 2 0 – 0 2 0 7 2 3 2
Nucleus 4 1 0 0 0 1 – 1 0 5 0 1 1 0 6 2 – 0 0 0 0 0 1 0
Nuclear Periphery 0 1 0 0 0 0 – 2 4 2 1 0 1 0 0 0 – 0 1 0 1 0 1 0
Nucleolus 1 0 0 0 0 1 – 3 0 0 2 1 0 0 0 0 – 0 0 0 0 0 1 1
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 1 1
Vac/Vac Membrane 2 0 0 0 2 1 – 23 25 9 4 4 5 1 2 32 – 20 4 0 2 5 6 2
Unique Cell Count 821 203 314 240 379 433 462 469 472 386 462 815 580 926 148 104 834 204 321 517 503 521
Labelled Cell Count 843 213 338 281 412 529 609 650 610 530 600 854 603 981 192 141 834 204 321 517 503 521


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.6 8.7 5.2 6.2 6.2 5.2 – 5.4 4.6 5.0 4.7 4.7 8.3 8.4 8.3 14.7 – 13.6 8.7 8.9 8.8
Std Deviation (1e-4) 1.0 1.1 0.9 1.4 1.1 1.0 – 1.4 1.0 0.9 0.9 0.8 1.1 1.2 1.1 10.5 – 2.7 1.3 1.4 1.4
Intensity Change (Log2) – – – 0.26 0.26 0.01 – 0.05 -0.17 -0.06 -0.13 -0.13 0.68 0.7 0.68 1.5 – 1.39 0.74 0.78 0.76

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Bud -2.2 -3.1 -2.7 – -0.8 0 -2.1 0 0 0 0 0 0 – 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Cell Periphery 0 0 0 – 0.7 0 0 0 0 2.4 2.0 3.0 7.1 – 7.3
Cytoplasm -1.7 -2.0 -5.8 – -9.6 -10.3 -10.7 -10.9 -11.7 -1.2 0.3 0.5 -6.5 – -3.8
Endoplasmic Reticulum 0 0 0 – 0 0 0.9 0 0 0 0 0 0 – 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Mitochondria 5.9 3.1 10.0 – 13.5 0 14.8 0 0 0 0 0 0 – 0
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0
Vacuole 0 0 0 – 4.0 4.2 0 0 0 0 0 0 8.5 – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.1529 6.5855 6.1828 6.0758 5.3744 6.3162 4.2105 5.4328 4.6243 4.5317 4.5029 4.8847 6.1518 7.4428 6.7669 6.6511 6.6944 6.834
Actin 0.0053 0.0001 0.0112 0.0204 0.0094 0.002 0.0095 0.0006 0.0096 0.0327 0.0113 0.0017 0.0004 0.0002 0.0002 0.0002 0.0002 0.0001
Bud 0.0002 0.0001 0.0035 0.0015 0.001 0.0004 0.0018 0.0021 0.0012 0.0027 0.0004 0.0003 0.0001 0.0001 0.0003 0.0003 0.0001 0.0001
Bud Neck 0.0003 0.0001 0.0005 0.0009 0.0018 0.0013 0.0038 0.0002 0.001 0.0021 0.0016 0.0021 0.0001 0.0001 0.0003 0.0003 0.0002 0.0004
Bud Periphery 0.0003 0 0.0015 0.0014 0.001 0.0006 0.0019 0.0012 0.0006 0.0039 0.0007 0.0004 0 0 0.0001 0.0001 0 0.0001
Bud Site 0.0003 0.0004 0.0022 0.0019 0.0016 0.0011 0.0049 0.0043 0.0101 0.0017 0.0011 0.0003 0.0001 0.0012 0.0004 0.0002 0.0001 0
Cell Periphery 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0003 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0
Cytoplasm 0.9031 0.9599 0.9057 0.8314 0.7738 0.948 0.8462 0.9419 0.8881 0.8222 0.8338 0.9393 0.9235 0.9756 0.9589 0.9222 0.9067 0.961
Cytoplasmic Foci 0.0231 0.0061 0.012 0.0289 0.0276 0.0111 0.0224 0.013 0.0212 0.0238 0.021 0.0133 0.0052 0.0047 0.0067 0.0129 0.0272 0.0086
Eisosomes 0 0 0.0001 0.0001 0.0001 0 0.0001 0 0 0.0001 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0059 0.0046 0.0047 0.0038 0.007 0.006 0.0118 0.0019 0.0084 0.0034 0.0054 0.0042 0.0187 0.0029 0.0048 0.0094 0.0026 0.0051
Endosome 0.0224 0.0079 0.03 0.0452 0.0733 0.0148 0.0436 0.0103 0.0212 0.0438 0.0632 0.0173 0.0064 0.0037 0.0135 0.0381 0.0339 0.0121
Golgi 0.0028 0.0005 0.0037 0.0048 0.0131 0.0007 0.0076 0.0024 0.0021 0.0076 0.0054 0.0033 0.0005 0.0005 0.0006 0.0007 0.0009 0.0006
Lipid Particles 0.0021 0 0.0009 0.0031 0.0078 0.0001 0.0017 0.0001 0.0031 0.0159 0.0054 0.0009 0.0001 0.0001 0 0.0001 0.0002 0
Mitochondria 0.0032 0.0002 0.0045 0.0045 0.0108 0.0017 0.0061 0.0009 0.0007 0.0065 0.0226 0.0024 0.0002 0.0002 0.0004 0.0002 0.0003 0.0013
None 0.018 0.0159 0.0065 0.0127 0.0056 0.0043 0.021 0.0161 0.0214 0.0087 0.0048 0.0092 0.0397 0.0082 0.0091 0.0044 0.0196 0.008
Nuclear Periphery 0.0033 0.0005 0.0024 0.0056 0.0302 0.0027 0.0049 0.0004 0.001 0.0016 0.0041 0.0006 0.001 0.0003 0.0006 0.0014 0.0007 0.0005
Nucleolus 0.0001 0 0.0001 0.0004 0.0014 0.0003 0.0005 0 0.0001 0.0001 0.0007 0 0 0 0 0 0 0
Nucleus 0.0011 0.0009 0.0018 0.0033 0.0143 0.0018 0.0033 0.0009 0.0014 0.0016 0.002 0.0012 0.0008 0.0005 0.0009 0.0013 0.0009 0.0007
Peroxisomes 0.0038 0 0.0011 0.0164 0.0041 0.0006 0.0016 0.0003 0.0035 0.0084 0.0031 0.0005 0 0 0 0 0.0001 0
Punctate Nuclear 0.0015 0.0001 0.0012 0.0031 0.005 0.0004 0.0018 0.0005 0.001 0.0033 0.0051 0.0004 0.0001 0.0001 0.0001 0.0002 0.0004 0.0001
Vacuole 0.0025 0.002 0.0053 0.0082 0.0072 0.0016 0.0041 0.0023 0.0034 0.0076 0.0061 0.0018 0.0026 0.0012 0.0026 0.0066 0.0052 0.0011
Vacuole Periphery 0.0007 0.0003 0.0009 0.0022 0.0037 0.0005 0.0013 0.0003 0.0006 0.0022 0.002 0.0005 0.0003 0.0002 0.0005 0.0012 0.0007 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 44.3332 64.5842 52.281 59.3017 48.9644 85.3352 54.1701 64.1073 50.7181 64.424
Translational Efficiency 3.594 2.1967 2.1583 2.0609 3.0079 1.592 1.8767 1.7752 2.0033 2.1711

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1864 1353 352 1650 1396 2040 1446 1194 3260 3393 1798 2844

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 778.30 893.25 1018.61 1070.27 822.04 923.90 958.74 1034.70 797.03 911.68 970.46 1055.34
Standard Deviation 106.44 129.67 152.99 152.49 112.03 117.01 138.80 147.49 111.00 123.13 143.67 151.43
Intensity Change Log 2 — 0.198738 0.388204 0.459577 — 0.168528 0.221931 0.331932 — 0.183299 0.305190 0.395421

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000269 0.000307 0.000464 0.001003 0.000261 0.000152 0.000465 0.000678 0.000265 0.000214 0.000465 0.000866
Bud Neck 0.008742 0.004086 0.001463 0.002002 0.004778 0.004340 0.001509 0.002691 0.007045 0.004239 0.001500 0.002291
Bud Site 0.021423 0.026893 0.008358 0.034100 0.014806 0.017456 0.019861 0.034881 0.018589 0.021219 0.017609 0.034428
Cell Periphery 0.000225 0.000108 0.000129 0.000089 0.000126 0.000084 0.000081 0.000068 0.000182 0.000094 0.000091 0.000080
Cytoplasm 0.508026 0.625158 0.654543 0.738317 0.587346 0.672338 0.825611 0.714664 0.541992 0.653525 0.792120 0.728387
Cytoplasmic Foci 0.309052 0.211932 0.063054 0.049302 0.236950 0.192439 0.055661 0.057915 0.278177 0.200212 0.057108 0.052918
Eisosomes 0.000158 0.000037 0.000036 0.000015 0.000068 0.000035 0.000008 0.000013 0.000120 0.000036 0.000014 0.000014
Endoplasmic Reticulum 0.003788 0.001777 0.001560 0.000763 0.003220 0.001148 0.000382 0.000232 0.003545 0.001399 0.000613 0.000540
Endosome 0.028074 0.026347 0.010753 0.005730 0.023221 0.016582 0.004266 0.006908 0.025996 0.020476 0.005536 0.006224
Golgi 0.022012 0.009977 0.000337 0.003401 0.010940 0.009071 0.002533 0.003029 0.017271 0.009432 0.002103 0.003245
Lipid Particles 0.004955 0.001731 0.002088 0.000978 0.003300 0.001383 0.000683 0.000661 0.004246 0.001521 0.000958 0.000845
Mitochondria 0.006798 0.001438 0.000078 0.003860 0.003130 0.001449 0.001298 0.001774 0.005227 0.001445 0.001059 0.002984
Mitotic Spindle 0.001190 0.003106 0.003562 0.023137 0.001127 0.002614 0.004758 0.022313 0.001163 0.002810 0.004524 0.022791
None 0.001020 0.000938 0.001457 0.000590 0.001099 0.000953 0.001181 0.000674 0.001054 0.000947 0.001235 0.000625
Nuclear Periphery 0.000150 0.000056 0.000434 0.000122 0.000144 0.000028 0.000054 0.000132 0.000148 0.000039 0.000128 0.000126
Nuclear Periphery Foci 0.000335 0.000883 0.009514 0.002157 0.000404 0.000293 0.001747 0.001530 0.000365 0.000529 0.003268 0.001894
Nucleolus 0.000235 0.000233 0.000232 0.000249 0.000266 0.000222 0.000173 0.000241 0.000248 0.000226 0.000184 0.000246
Nucleus 0.010949 0.006436 0.047301 0.013680 0.012015 0.009403 0.014947 0.012081 0.011405 0.008220 0.021281 0.013009
Peroxisomes 0.002555 0.002956 0.000370 0.001819 0.001617 0.001750 0.000559 0.002176 0.002153 0.002231 0.000522 0.001969
Vacuole 0.062475 0.072166 0.193696 0.117422 0.090401 0.065368 0.063617 0.136072 0.074433 0.068079 0.089083 0.125252
Vacuole Periphery 0.007569 0.003436 0.000573 0.001264 0.004780 0.002892 0.000607 0.001268 0.006375 0.003109 0.000600 0.001266

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.14 -1.61 -3.24 -2.89 -0.53 2.04 -1.17 -1.34 -2.51 0.18 1.83 -1.53 -3.31 -4.20 -0.34
Bud Neck 7.81 14.81 14.73 5.95 -0.61 1.07 8.53 6.39 6.30 -1.85 7.64 16.34 15.79 9.54 -1.60
Bud Site -3.17 6.22 0.26 2.63 -4.79 -1.79 -1.32 -3.12 -2.15 -1.74 -2.32 1.57 -1.93 -0.35 -2.76
Cell Periphery 7.86 6.19 11.10 4.96 6.17 3.44 2.63 5.86 6.09 1.55 9.14 6.48 12.44 7.09 2.05
Cytoplasm -12.51 -7.32 -21.06 -6.48 -4.27 -9.73 -23.71 -8.94 -0.86 12.21 -17.82 -31.01 -21.49 -4.77 10.51
Cytoplasmic Foci 14.31 43.49 54.65 30.92 3.54 6.86 32.47 32.63 29.61 0.95 16.73 56.09 61.77 43.63 3.40
Eisosomes 12.61 13.77 17.23 4.85 8.93 6.66 12.91 12.17 11.56 -3.99 14.75 19.86 20.31 10.09 1.98
Endoplasmic Reticulum 2.76 3.69 5.79 2.78 6.51 2.76 4.96 5.35 1.95 1.20 4.03 7.06 7.82 2.99 2.06
Endosome 0.98 13.64 22.02 14.45 6.64 4.75 16.05 14.79 12.03 -1.22 5.06 24.53 26.36 19.22 1.96
Golgi 9.38 28.33 22.99 7.40 -2.60 2.02 8.96 9.30 8.39 0.36 10.25 20.23 23.36 11.80 0.09
Lipid Particles 8.53 7.21 11.25 4.72 4.59 7.69 10.12 10.99 6.06 1.76 11.49 13.53 14.97 7.10 2.51
Mitochondria 5.42 7.19 4.33 -0.28 -2.14 2.14 2.32 2.50 0.86 0.05 5.74 5.67 4.97 0.17 -0.82
Mitotic Spindle -1.82 -1.03 -6.22 -5.08 -3.69 -1.99 -2.97 -5.42 -4.68 -3.77 -2.62 -3.07 -8.24 -7.00 -5.59
None 0.27 -0.75 1.50 1.23 2.95 0.31 0.13 1.01 2.38 0.99 0.42 -0.03 1.68 2.60 1.34
Nuclear Periphery 1.60 -5.42 -0.98 -9.31 7.91 2.25 1.12 -0.37 -5.95 -3.32 2.71 -0.59 -1.02 -11.66 -1.17
Nuclear Periphery Foci -2.26 -11.31 -5.23 -2.36 9.04 2.33 -9.92 -8.43 -9.52 2.09 -1.66 -14.20 -7.63 -5.77 6.42
Nucleolus -0.07 0.20 0.60 0.74 0.58 0.72 1.31 0.85 0.42 -0.55 0.44 1.28 1.00 0.85 -0.38
Nucleus 5.38 -14.20 -9.00 -17.02 10.75 3.42 -6.67 -4.77 -8.16 1.96 5.31 -13.35 -10.18 -17.11 5.78
Peroxisomes -0.87 7.97 4.98 4.73 -4.06 -0.49 6.49 0.98 1.33 -2.43 -0.26 9.43 4.46 4.79 -3.85
Vacuole -3.09 -13.13 -23.37 -20.36 2.38 6.88 0.09 -15.19 -20.05 -14.80 2.45 -9.77 -27.41 -29.26 -13.90
Vacuole Periphery 8.07 15.71 15.18 9.73 -0.73 3.89 10.06 8.94 6.86 -0.95 9.08 18.33 17.48 11.47 -1.12
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the heterohexameric cochaperone prefoldin complex; complex binds specifically to cytosolic chaperonin and transfers target proteins to it
Localization
Cell Percentages cytoplasm (98%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Gim4

Gim4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gim4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available