Standard name
Human Ortholog
Description Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Vps21p-GFP; has potential role in vacuolar function, as suggested by its ability to bind Vac8p; likely member of; Vab2p-GFP-fusion localizes to cytoplasm in punctate pattern
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0.05 0.05
Bud Neck 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.9 0.91 0.92 0.94 0.94 0.88 0.87 – 0.71 0.76 0.69 0.64 0.95 0.96 0.87 – – – 0.48 0.72 0.5 0.71 0.69 0.62
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.08 – – – 0.06 0 0.1 0.07 0.05 0.07
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0.2 0.06 0 0 0 0.08 0.08 – 0.4 0.25 0.37 0.39 0 0 0 – – – 0.31 0.12 0.2 0.08 0.06 0.08
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0.05 0 0.05 0.06 0.06 – 0 0.05 0.05 0.07 0 0 0.05 – – – 0 0 0.06 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0.06 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 2 0 0 0 1 – 0 0 0 1 2 0 0 – – – 0 2 10 1 4 5
Bud 0 3 1 2 0 3 10 – 15 11 15 26 1 1 0 – – – 0 0 6 6 22 25
Bud Neck 0 2 22 2 7 8 26 – 7 14 11 12 1 2 1 – – – 0 1 4 2 2 4
Bud Site 0 0 0 0 0 0 0 – 4 1 2 5 0 0 0 – – – – – – – – –
Cell Periphery 0 2 0 2 1 1 2 – 0 7 0 2 1 0 0 – – – 0 1 3 0 0 3
Cytoplasm 45 215 414 282 333 458 586 – 379 441 375 453 178 250 270 – – – 36 167 229 291 298 297
Endoplasmic Reticulum 0 1 2 1 0 1 1 – 2 0 1 0 4 0 0 – – – 0 0 6 5 4 5
Endosome 1 1 5 0 5 18 11 – 2 3 9 2 2 5 26 – – – 4 10 44 27 20 32
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 1 1 0 – – – 1 0 0 1 1 1
Mitochondria 10 14 0 2 1 41 57 – 210 145 201 274 0 1 0 – – – 23 27 91 31 26 38
Nucleus 0 0 0 1 0 0 2 – 0 4 3 8 1 1 0 – – – 0 0 0 4 7 3
Nuclear Periphery 0 0 0 1 0 0 1 – 0 0 0 3 0 0 1 – – – 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 – – – 0 0 1 0 0 1
Peroxisomes 0 0 0 0 1 3 1 – 1 0 1 3 0 0 4 – – – 0 0 2 0 0 0
SpindlePole 0 4 23 9 19 33 40 – 22 31 27 49 1 4 17 – – – 1 5 27 15 18 18
Vac/Vac Membrane 2 1 3 3 3 10 7 – 6 10 9 5 1 1 3 – – – 4 7 13 17 13 21
Unique Cell Count 50 236 450 299 353 521 676 531 581 547 711 187 260 310 75 232 463 413 433 476
Labelled Cell Count 58 244 472 305 370 576 745 648 668 654 843 193 266 322 75 232 463 413 433 476


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 3.1 4.9 4.6 5.2 4.2 4.0 – 3.3 3.7 3.5 3.6 4.9 5.1 4.8 – – – 6.2 6.3 6.3
Std Deviation (1e-4) 0.9 0.5 1.4 2.0 2.2 1.6 1.2 – 1.2 1.0 0.8 0.8 1.6 1.5 1.5 – – – 2.3 2.4 2.3
Intensity Change (Log2) – – – -0.09 0.09 -0.23 -0.27 – -0.54 -0.41 -0.46 -0.43 0.0 0.06 -0.01 – – – 0.35 0.38 0.38


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.3514 3.0878 3.8104 3.1889 3.9304 3.0895 4.1771 2.4365 2.4954 2.1205 2.15 2.5016 1.7055 -0.128 0.097 -0.6586 -0.4968 -0.6727
Actin 0.1183 0.0005 0.0206 0.029 0.1497 0.02 0.0601 0.002 0.0165 0.0306 0.0528 0.0055 0.0511 0.0055 0.0314 0.0004 0 0.0001
Bud 0.0019 0.0014 0.0013 0.0008 0.0013 0.0014 0.0021 0.002 0.0009 0.0067 0.0035 0.0001 0.0012 0.0002 0.0005 0.0001 0 0
Bud Neck 0.0189 0.0002 0.0027 0.0108 0.0009 0.0091 0.0133 0.0013 0.0004 0.0005 0.0072 0.0005 0.0157 0.0012 0.0032 0.0001 0 0.0001
Bud Periphery 0.0041 0.0039 0.002 0.0011 0.0023 0.004 0.0057 0.004 0.0018 0.0344 0.0091 0.0002 0.0013 0.0005 0.0005 0.0002 0 0
Bud Site 0.0241 0.0047 0.0274 0.0023 0.0032 0.0008 0.042 0.0048 0.0013 0.0007 0.0106 0.0001 0.0214 0.005 0.0419 0.0003 0 0
Cell Periphery 0.0018 0.0003 0.0007 0.0004 0.0002 0.0003 0.0018 0.0005 0.0003 0.0002 0.0013 0.0001 0.001 0.0009 0.0006 0.0002 0.0001 0
Cytoplasm 0.0387 0.0447 0.049 0.057 0.0307 0.0494 0.0311 0.0925 0.092 0.0781 0.0687 0.0667 0.0321 0.0914 0.1084 0.1302 0.015 0.0937
Cytoplasmic Foci 0.0893 0.0701 0.0854 0.1308 0.0917 0.1782 0.0649 0.1114 0.0811 0.1722 0.1928 0.1456 0.1833 0.0615 0.1266 0.1889 0.2563 0.1255
Eisosomes 0.0019 0.0003 0.0006 0.0006 0.0011 0.0001 0.0014 0.0002 0.0006 0.0004 0.0006 0.0002 0.0006 0.0011 0.0005 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0054 0.0011 0.0064 0.0016 0.0053 0.002 0.0127 0.0032 0.0047 0.0013 0.0024 0.0018 0.0028 0.0034 0.0073 0.0066 0.0004 0.0008
Endosome 0.0485 0.0205 0.0299 0.0861 0.0486 0.056 0.0571 0.0849 0.0561 0.0825 0.1325 0.0344 0.0833 0.0307 0.0683 0.1426 0.0071 0.0491
Golgi 0.0211 0.0012 0.0078 0.0079 0.023 0.0053 0.0107 0.0051 0.0094 0.0065 0.0208 0.0029 0.0257 0.0019 0.0063 0.0094 0.0004 0.0015
Lipid Particles 0.0334 0.0162 0.0162 0.057 0.0192 0.03 0.0566 0.0157 0.0196 0.0302 0.0373 0.0296 0.0675 0.0093 0.0377 0.0738 0.0557 0.0425
Mitochondria 0.0055 0.0016 0.011 0.0102 0.0298 0.0028 0.0071 0.0073 0.015 0.0025 0.0244 0.0008 0.0057 0.0173 0.002 0.0054 0 0.0002
None 0.5052 0.8229 0.699 0.568 0.517 0.6128 0.4779 0.6477 0.6688 0.5246 0.3974 0.6795 0.3405 0.7581 0.5381 0.3972 0.6617 0.6765
Nuclear Periphery 0.0129 0.0004 0.005 0.0025 0.012 0.0037 0.0556 0.0014 0.0064 0.0009 0.0011 0.0178 0.0045 0.001 0.0064 0.0028 0.0001 0.0004
Nucleolus 0.0028 0.0006 0.0013 0.0007 0.0008 0.0007 0.0047 0.0005 0.0004 0.0007 0.0004 0.0003 0.0065 0.0006 0.001 0.0004 0 0.0001
Nucleus 0.0028 0.0004 0.0034 0.0018 0.0024 0.0011 0.0435 0.0008 0.0012 0.0007 0.0007 0.001 0.1008 0.0006 0.0028 0.0009 0 0.0002
Peroxisomes 0.0279 0.0023 0.0178 0.0137 0.031 0.0093 0.0171 0.0023 0.0166 0.0166 0.0272 0.0075 0.0336 0.0051 0.0057 0.0153 0.0012 0.0061
Punctate Nuclear 0.0282 0.0013 0.0067 0.0111 0.0269 0.0038 0.0176 0.002 0.003 0.0059 0.0011 0.0037 0.0108 0.0013 0.0049 0.0027 0.0013 0.0011
Vacuole 0.0056 0.0049 0.0048 0.0052 0.0014 0.0082 0.012 0.0095 0.0028 0.0032 0.0062 0.0012 0.0091 0.0026 0.0049 0.0186 0.0003 0.0016
Vacuole Periphery 0.0017 0.0003 0.001 0.0014 0.0013 0.0011 0.005 0.0012 0.0011 0.0006 0.0018 0.0006 0.0014 0.0006 0.0008 0.0038 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 3.2491 6.9709 1.7242 7.7063 5.8977 3.8968 5.2862 6.7392 6.001 8.4988
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1989 1409 1478 1450 1588 2033 165 1553 3577 3442 1643 3003

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 643.49 647.16 802.11 798.37 610.63 714.49 806.82 779.48 628.90 686.93 802.58 788.60
Standard Deviation 71.16 88.67 96.28 128.95 61.35 75.11 109.69 106.14 68.95 87.45 97.72 118.08
Intensity Change Log 2 — 0.008205 0.317882 0.311140 — 0.226615 0.401948 0.352214 — 0.118681 0.359426 0.331285

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000157 0.000607 0.000127 0.001095 0.000232 0.000483 0.000186 0.000401 0.000190 0.000534 0.000133 0.000736
Bud Neck 0.037580 0.056981 0.029718 0.014421 0.025214 0.056862 0.010658 0.022310 0.032090 0.056910 0.027804 0.018500
Bud Site 0.004886 0.020991 0.021271 0.037118 0.004835 0.011789 0.013820 0.045655 0.004864 0.015556 0.020523 0.041533
Cell Periphery 0.000214 0.000151 0.000083 0.000289 0.000205 0.000155 0.000391 0.000198 0.000210 0.000153 0.000114 0.000242
Cytoplasm 0.322312* 0.295321* 0.411336* 0.389867* 0.364114* 0.326410* 0.217112* 0.450497* 0.340870* 0.313683* 0.391831* 0.421222*
Cytoplasmic Foci 0.259224* 0.271298* 0.032402 0.044495 0.302022* 0.272781* 0.094053 0.039110 0.278224* 0.272174* 0.038593 0.041710
Eisosomes 0.000307 0.000160 0.000025 0.000064 0.000344 0.000216 0.000398 0.000053 0.000324 0.000193 0.000063 0.000058
Endoplasmic Reticulum 0.003187 0.001108 0.001763 0.002808 0.000945 0.000666 0.001508 0.001364 0.002191 0.000847 0.001737 0.002061
Endosome 0.034526 0.055804 0.024872 0.031563 0.017636 0.034286 0.040349 0.027034 0.027028 0.043095 0.026426 0.029221
Golgi 0.004074 0.008680 0.000201 0.010282 0.005510 0.005856 0.000391 0.002287 0.004711 0.007012 0.000220 0.006147
Lipid Particles 0.026952 0.013508 0.002426 0.003055 0.028875 0.014498 0.009013 0.002046 0.027806 0.014093 0.003088 0.002533
Mitochondria 0.012690 0.028605 0.001945 0.009450 0.013090 0.019459 0.000386 0.009014 0.012867 0.023203 0.001789 0.009224
Mitotic Spindle 0.001315 0.004907 0.025626 0.055192 0.000715 0.003776 0.004519 0.037280 0.001049 0.004239 0.023507 0.045929
None 0.003187 0.004638 0.003944 0.004987 0.001910 0.002247 0.005534 0.003985 0.002620 0.003226 0.004104 0.004469
Nuclear Periphery 0.001183 0.000832 0.004931 0.002654 0.000770 0.000801 0.001196 0.001691 0.001000 0.000814 0.004556 0.002156
Nuclear Periphery Foci 0.000372 0.000462 0.001522 0.002426 0.000431 0.000270 0.004530 0.001147 0.000398 0.000348 0.001824 0.001764
Nucleolus 0.001849 0.003603 0.004875 0.001291 0.001257 0.002220 0.006083 0.001488 0.001586 0.002786 0.004996 0.001393
Nucleus 0.163561* 0.090454 0.369757* 0.194772* 0.178585* 0.144736* 0.488457* 0.226203* 0.170231* 0.122515 0.381677* 0.211027*
Peroxisomes 0.011657 0.028910 0.004159 0.007674 0.017171 0.023918 0.020656 0.004905 0.014105 0.025961 0.005816 0.006242
Vacuole 0.108223 0.107467 0.058598 0.178157 0.035000 0.075944 0.080393 0.118162 0.075716 0.088848 0.060787 0.147131
Vacuole Periphery 0.002543 0.005513 0.000419 0.008342 0.001140 0.002628 0.000367 0.005170 0.001920 0.003809 0.000413 0.006702

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.76 0.54 -3.16 -1.09 -3.22 -1.56 -0.80 -1.63 0.97 -0.67 -3.32 1.03 -3.55 -0.49 -3.86
Bud Neck -5.28 -0.57 10.66 13.43 9.59 -10.03 3.54 2.52 12.40 -2.07 -10.33 -1.68 9.34 18.36 8.20
Bud Site -10.92 -4.74 -7.81 -0.61 -2.05 -5.01 -1.46 -8.98 -6.24 -2.03 -10.88 -4.97 -11.94 -5.44 -3.58
Cell Periphery 2.01 4.81 1.09 -0.70 -3.78 1.82 -2.91 2.07 0.57 4.86 2.69 5.25 2.15 -0.31 -3.87
Cytoplasm 2.98 -3.28 0.25 -2.42 3.14 4.39 9.92 -2.18 -6.21 -10.86 4.41 0.47 -1.92 -5.76 -1.91
Cytoplasmic Foci -1.26 40.03 42.79 37.95 1.98 3.87 16.42 45.15 43.99 5.78 1.30 52.24 61.67 58.29 4.26
Eisosomes 7.86 15.74 13.33 12.72 -13.95 2.89 -0.34 6.56 12.75 6.54 5.72 11.58 11.91 16.37 -0.01
Endoplasmic Reticulum 5.30 1.81 -1.55 -11.00 -5.16 2.30 -3.59 -7.03 -10.61 0.97 6.01 -0.99 -2.87 -14.89 -2.53
Endosome -6.46 3.17 6.76 11.65 2.70 -7.75 -3.12 0.16 6.45 3.12 -8.32 -0.26 5.57 12.53 3.92
Golgi -5.07 9.73 0.26 3.63 -3.44 -0.22 7.46 6.22 7.33 -2.42 -3.57 12.06 3.68 6.43 -4.19
Lipid Particles 8.12 18.52 18.53 9.54 0.03 7.90 7.96 16.13 15.81 4.96 11.45 22.79 24.57 17.86 4.18
Mitochondria -6.40 9.43 5.59 10.01 -1.62 -3.49 10.66 4.97 8.22 -3.63 -7.04 13.21 7.40 12.98 -2.80
Mitotic Spindle -3.34 -8.58 -10.56 -9.41 -2.55 -3.70 -1.71 -9.43 -8.01 -4.55 -4.70 -8.85 -14.07 -12.38 -2.03
None -1.26 -0.75 -0.84 0.72 -0.23 -0.80 -1.39 -4.98 -3.53 0.41 -1.10 -2.27 -2.83 -1.04 -0.18
Nuclear Periphery 2.14 -13.81 -10.71 -11.82 5.17 -0.21 -3.14 -11.49 -10.23 -3.29 1.64 -14.53 -14.91 -15.46 6.98
Nuclear Periphery Foci -2.10 -5.68 -7.09 -6.59 -0.24 1.02 -3.07 -3.50 -4.22 2.81 0.09 -6.27 -7.90 -7.85 2.76
Nucleolus -3.92 -7.42 2.24 4.65 7.74 -2.88 -2.32 -2.68 -0.19 1.97 -4.59 -7.94 -1.29 3.14 7.63
Nucleus 12.76 -23.99 -8.81 -18.39 14.45 5.47 -9.35 -11.78 -16.71 5.70 11.13 -25.75 -14.93 -23.72 14.45
Peroxisomes -8.31 7.68 5.98 11.39 0.04 -3.48 -0.57 9.19 13.18 2.63 -8.67 7.13 11.02 17.19 2.21
Vacuole -0.40 5.06 -21.82 -20.89 -24.57 -13.87 -5.74 -25.74 -17.78 -2.91 -4.77 -3.04 -30.88 -27.72 -24.40
Vacuole Periphery -7.14 12.46 -0.85 2.57 -3.67 -6.55 6.16 -1.87 0.15 -2.89 -8.38 14.24 -1.72 1.62 -4.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Vps21p-GFP; has potential role in vacuolar function, as suggested by its ability to bind Vac8p; likely member of; Vab2p-GFP-fusion localizes to cytoplasm in punctate pattern
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Vab2

Vab2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vab2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available