Standard name
Human Ortholog
Description Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0.07 0.11 0.13 0.13 0.16 0.14 0.11 0 0 0 0.07 0.1 0.09 0 0 0 0 0 0
Cytoplasm 0.28 0.17 0.18 0.16 0.35 0.48 0.51 0.49 0.64 0.55 0.64 0.68 0.23 0.19 0.16 0.3 0.46 0.5 0.16 0.2 0.1 0.05 0.05 0
Endoplasmic Reticulum 0.6 0.8 0.65 0.58 0.36 0.31 0.33 0.39 0.24 0.29 0.21 0.2 0.67 0.72 0.73 0.09 0.14 0.09 0.46 0.42 0.52 0.41 0.32 0.32
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0
Golgi 0 0 0 0.05 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.06 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.07 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0 0.13 0.23 0.25 0.17 0.14 0.08 0.11 0.11 0.1 0.09 0.09 0.08 0.12 0.48 0.27 0.26 0.27 0.19 0.22 0.39 0.54 0.55
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 1 1 2 7 1 10 8 11 0 0 1 1 0 0 0 7 3 2 0 0
Bud 0 3 3 0 3 9 8 16 5 15 7 16 3 1 4 0 2 0 2 8 2 8 5 9
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 3 1 5 24 49 74 49 71 47 53 1 5 4 3 7 3 0 0 0 0 0 0
Cytoplasm 34 30 33 35 82 154 225 287 241 248 217 321 50 59 63 14 32 17 40 59 30 16 13 8
Endoplasmic Reticulum 73 137 121 127 83 100 147 228 90 129 72 94 148 222 278 4 10 3 116 126 153 122 92 123
Endosome 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 5 16 12 11 4 7
Golgi 2 0 7 10 5 1 3 2 0 2 1 1 11 11 14 2 1 2 2 1 10 5 3 5
Mitochondria 0 0 0 1 0 2 0 0 1 0 3 0 0 0 0 0 0 0 0 1 0 1 0 1
Nucleus 0 0 1 2 2 1 0 1 2 0 2 3 0 0 0 0 0 0 3 3 1 2 3 5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 4 3 3 1 3
Nucleolus 8 4 13 7 8 9 3 7 1 3 0 0 6 1 4 1 3 1 0 0 0 0 1 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0
Vac/Vac Membrane 9 1 24 51 57 54 64 46 40 51 35 41 20 25 45 22 19 9 66 58 66 119 155 211
Unique Cell Count 122 172 187 220 231 322 445 586 376 447 341 470 222 308 383 46 70 34 251 303 295 303 286 386
Labelled Cell Count 126 177 205 235 246 355 501 669 430 529 394 540 240 324 413 47 74 35 251 303 295 303 286 386


Cell Periphery, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 96.8 108.9 64.2 63.6 51.1 42.6 43.1 41.5 42.6 42.2 39.8 42.1 71.8 71.4 71.3 97.6 98.4 100.8 74.0 69.5 74.2
Std Deviation (1e-4) 24.4 26.8 19.2 17.4 17.6 16.0 14.1 12.8 13.6 13.8 12.6 12.5 21.6 20.5 20.2 28.8 29.3 29.3 20.5 21.8 22.2
Intensity Change (Log2) – – – -0.01 -0.33 -0.59 -0.57 -0.63 -0.59 -0.61 -0.69 -0.61 0.16 0.15 0.15 0.61 0.62 0.65 0.2 0.11 0.21

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1.2 0 1.2 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 2.8 3.9 4.4 4.4 5.1 4.6 4.0 0 0 0 0 0 0
Cytoplasm -0.5 4.1 6.8 7.7 7.6 10.4 8.7 10.1 11.8 1.2 0.4 -0.4 1.9 4.6 4.1
Endoplasmic Reticulum -1.4 -5.9 -7.4 -7.4 -6.2 -9.4 -8.4 -9.9 -11.0 0.4 1.7 1.9 -6.8 -7.2 -6.0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.4 -1.0 0 0 0 0 0 0 0 0.6 -0.1 -0.1 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.8 -1.6 -2.2 0 0 0 0 0 0 -2.0 -4.3 -3.9 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.7 3.0 1.2 0.5 -2.1 -0.8 -0.5 -0.9 -1.6 -1.2 -1.7 -0.4 5.3 2.7 2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 114.2517 140.9982 129.7823 123.9543 121.2546 129.1022 105.3123 144.9189 132.9916 124.2206 127.5113 132.9213 73.4734 119.9213 108.0838 77.8039 58.8719 117.1746
Actin 0.0003 0 0 0 0.0081 0 0.0084 0 0.0003 0 0 0 0.1125 0 0.0002 0 0.0643 0.0074
Bud 0 0.0001 0 0 0.0001 0.0001 0.0002 0.0001 0.0003 0 0.0001 0.0001 0.0018 0.0001 0.0007 0.0009 0.0015 0.0022
Bud Neck 0.0001 0.0001 0.0001 0 0.0001 0.0003 0.0004 0.0002 0.0002 0.0001 0.0001 0.0002 0.0092 0.0001 0.0009 0.0001 0.0007 0.0081
Bud Periphery 0.0002 0.0003 0.0002 0.0001 0.0003 0.0004 0.0011 0.0004 0.0008 0.0002 0.0008 0.0006 0.006 0.0003 0.0026 0.0002 0.002 0.0021
Bud Site 0.0001 0.0002 0 0 0.0001 0 0.0005 0.0001 0.0013 0 0 0 0.0035 0.0002 0.0011 0.0001 0.0024 0.0011
Cell Periphery 0.3929 0.3882 0.3872 0.3159 0.3554 0.3521 0.3173 0.374 0.3982 0.2981 0.3084 0.3219 0.2221 0.3458 0.2271 0.0896 0.1426 0.3122
Cytoplasm 0.0068 0.0161 0.0145 0.0015 0.0009 0.0205 0.0046 0.0032 0.0024 0.0009 0.001 0.0011 0.0236 0.0009 0.0085 0.2855 0.0069 0.0523
Cytoplasmic Foci 0.0009 0.0003 0.0002 0 0.0021 0.0003 0.0104 0.0002 0.0046 0.0006 0.0001 0.0003 0.0005 0.0002 0.001 0.002 0.0202 0.0017
Eisosomes 0.0002 0 0 0 0.0001 0 0.0003 0 0.0003 0 0 0 0.0017 0 0.0003 0 0.0002 0
Endoplasmic Reticulum 0.0033 0.0064 0.006 0.0008 0.001 0.0091 0.0051 0.0144 0.0062 0.0007 0.0026 0.0089 0.0067 0.0005 0.0013 0.0003 0.0124 0.0024
Endosome 0.0008 0.0003 0.0004 0.0003 0.0026 0.0015 0.003 0.0008 0.001 0.0008 0.0026 0.0014 0.003 0.0004 0.0056 0.0021 0.1367 0.0031
Golgi 0.0001 0 0 0 0.0027 0.0001 0.0012 0.0001 0.0002 0.0001 0.0002 0.0005 0.0025 0 0.0018 0 0.0496 0.0005
Lipid Particles 0.0169 0.0163 0.0228 0.0053 0.0176 0.0296 0.0335 0.054 0.0236 0.0602 0.0521 0.046 0.0111 0.0077 0.1194 0.0003 0.0129 0.0149
Mitochondria 0.0002 0 0 0 0.0005 0.0001 0.0045 0.0001 0.0014 0 0.0001 0.0001 0.0025 0.0001 0.0111 0.0001 0.0131 0.0009
None 0.0013 0 0 0 0.0012 0 0.0052 0 0.0014 0 0 0 0.0004 0 0.0002 0.0009 0.0017 0.0002
Nuclear Periphery 0.0052 0.0034 0.0024 0.0008 0.0023 0.006 0.0068 0.0036 0.006 0.0008 0.0018 0.0103 0.0163 0.0007 0.0012 0.0013 0.0168 0.0107
Nucleolus 0.0061 0.0033 0.0041 0.0004 0.0007 0.001 0.012 0.0017 0.0037 0.0023 0.0007 0.0021 0.0089 0.0326 0.049 0.0009 0.0011 0.0072
Nucleus 0.0019 0.0019 0.0009 0.0005 0.0006 0.0009 0.0046 0.0009 0.0009 0.0007 0.0009 0.0011 0.0094 0.0029 0.004 0.0018 0.0026 0.014
Peroxisomes 0.0003 0 0 0 0.0057 0 0.0063 0 0.0002 0 0 0 0.0002 0 0.0002 0 0.0034 0.0003
Punctate Nuclear 0.0007 0.0001 0 0 0.003 0 0.0038 0 0.0009 0 0 0 0.0002 0 0 0 0.0021 0.0006
Vacuole 0.5522 0.5562 0.5532 0.6575 0.5758 0.5636 0.5314 0.5255 0.5243 0.6089 0.5733 0.5538 0.5012 0.5412 0.5058 0.5465 0.2723 0.5165
Vacuole Periphery 0.0094 0.0067 0.0079 0.0167 0.0191 0.0144 0.0395 0.0206 0.0218 0.0254 0.0551 0.0514 0.0567 0.0663 0.0579 0.0675 0.2348 0.0415

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 380.3402 425.9352 499.0457 981.5486 579.8314 250.6349 576.1057 782.7645 620.2151 793.2768
Translational Efficiency 2.0213 2.7242 3.5306 0.9016 2.1763 4.0175 2.3477 1.8745 2.7553 2.0874

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1319 1560 1284 112 1452 1476 131 2584 2771 3036 1415 2696

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 4898.27 6312.28 9939.40 14008.24 4734.46 5439.91 10531.97 8678.63 4812.43 5888.16 9994.26 8900.04
Standard Deviation 1268.63 1786.52 2132.39 4250.08 1698.49 1474.02 2214.41 2860.51 1511.44 1698.94 2147.00 3118.33
Intensity Change Log 2 — 0.365889 1.020886 1.515932 — 0.200383 1.153504 0.874267 — 0.286913 1.087591 1.235841

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000297 0.000151 0.000199 0.000071 0.000080 0.000335 0.000083 0.000379 0.000183 0.000240 0.000188 0.000366
Bud Neck 0.001670 0.003708 0.004412 0.002063 0.001422 0.004338 0.003017 0.002749 0.001540 0.004015 0.004283 0.002721
Bud Site 0.001774 0.006102 0.002252 0.001099 0.003773 0.007114 0.000819 0.005752 0.002822 0.006594 0.002119 0.005558
Cell Periphery 0.125263 0.068545 0.133958 0.300081 0.057457 0.082208 0.250609 0.235265 0.089733 0.075188 0.144758 0.237958
Cytoplasm 0.001218 0.001643 0.000633 0.000071 0.023409 0.001386 0.000018 0.005344 0.012846 0.001518 0.000576 0.005124
Cytoplasmic Foci 0.000865 0.003611 0.000389 0.000049 0.003330 0.002454 0.000072 0.000729 0.002157 0.003049 0.000360 0.000700
Eisosomes 0.000108 0.000111 0.000525 0.000611 0.000034 0.000208 0.000718 0.000147 0.000069 0.000158 0.000543 0.000166
Endoplasmic Reticulum 0.039909 0.070792 0.086090 0.006560 0.039178 0.073703 0.017557 0.088147 0.039526 0.072207 0.079745 0.084758
Endosome 0.005631 0.031501 0.008831 0.000750 0.008681 0.031679 0.001129 0.005715 0.007229 0.031587 0.008118 0.005509
Golgi 0.007585 0.024507 0.012565 0.003545 0.015044 0.020952 0.008256 0.002808 0.011494 0.022779 0.012167 0.002839
Lipid Particles 0.054284 0.173491 0.152149 0.058683 0.050372 0.165856 0.043362 0.113214 0.052234 0.169779 0.142077 0.110949
Mitochondria 0.000164 0.000721 0.000233 0.000018 0.000231 0.000630 0.000033 0.000732 0.000199 0.000677 0.000214 0.000702
Mitotic Spindle 0.000060 0.000110 0.000073 0.000158 0.000061 0.000093 0.000056 0.000225 0.000061 0.000102 0.000072 0.000222
None 0.000180 0.000181 0.000042 0.000008 0.002959 0.000858 0.000009 0.000422 0.001636 0.000510 0.000039 0.000405
Nuclear Periphery 0.001229 0.001100 0.004644 0.004160 0.000650 0.001329 0.004785 0.004735 0.000926 0.001211 0.004657 0.004712
Nuclear Periphery Foci 0.003920 0.006132 0.004366 0.001118 0.006842 0.005670 0.001337 0.002297 0.005451 0.005908 0.004086 0.002248
Nucleolus 0.000202 0.000252 0.000086 0.000025 0.000721 0.000432 0.000035 0.000194 0.000474 0.000340 0.000081 0.000187
Nucleus 0.000205 0.000256 0.000105 0.000038 0.001291 0.000846 0.000044 0.000411 0.000774 0.000543 0.000099 0.000396
Peroxisomes 0.000141 0.000440 0.000170 0.000010 0.000172 0.000299 0.000006 0.003264 0.000158 0.000372 0.000155 0.003129
Vacuole 0.716730 0.555569 0.565817 0.615832 0.707053 0.557896 0.654538 0.519833 0.711659 0.556700 0.574031 0.523821
Vacuole Periphery 0.038564 0.051074 0.022461 0.005051 0.077237 0.041713 0.013517 0.007639 0.058829 0.046523 0.021633 0.007531

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.77 0.37 1.10 1.99 2.38 -3.83 -0.62 -3.73 -0.44 -3.40 -0.49 -0.23 -1.47 -1.58 -1.73
Bud Neck -3.79 -6.18 -0.44 1.56 2.55 -6.97 -2.51 -4.24 3.09 0.39 -7.28 -6.96 -3.95 2.87 3.44
Bud Site -5.45 -1.07 1.04 5.41 1.77 -3.38 2.88 -2.60 0.83 -4.61 -5.88 0.88 -3.75 0.66 -4.05
Cell Periphery 13.04 -1.66 -11.23 -15.10 -10.70 -6.64 -14.86 -45.62 -35.05 1.18 4.99 -13.08 -38.86 -44.51 -19.64
Cytoplasm -1.00 1.08 4.51 3.51 1.61 8.52 9.16 6.73 -6.12 -9.15 8.03 8.62 4.98 -5.66 -6.74
Cytoplasmic Foci -4.87 1.30 2.27 8.47 4.59 1.42 6.28 4.59 4.74 -3.64 -2.14 5.45 3.76 7.18 -1.99
Eisosomes -0.12 -9.87 -2.92 -2.92 -0.48 -5.96 -6.36 -8.81 1.96 5.28 -5.08 -12.69 -6.13 -0.46 9.76
Endoplasmic Reticulum -6.82 -8.25 9.75 15.96 15.27 -7.58 2.74 -12.05 -2.88 -8.73 -10.21 -8.30 -12.61 -3.12 -0.90
Endosome -16.98 -4.54 11.68 20.74 13.13 -12.99 11.22 4.23 15.47 -13.73 -20.85 -1.42 3.72 23.00 4.41
Golgi -10.79 -4.70 3.52 11.98 6.89 -3.52 3.07 11.35 13.99 2.68 -9.71 -0.54 13.29 20.24 11.45
Lipid Particles -16.50 -14.30 -0.32 7.03 5.78 -16.36 0.79 -12.70 7.25 -7.79 -23.29 -15.24 -13.46 10.33 4.83
Mitochondria -5.23 -1.68 6.37 6.87 4.82 -3.47 6.27 -5.26 -0.82 -7.61 -6.09 -0.82 -5.63 -0.40 -4.71
Mitotic Spindle -2.92 -0.91 -3.04 -1.38 -2.86 -3.20 0.54 -10.14 -7.54 -9.83 -4.20 -1.35 -10.04 -7.26 -9.95
None 0.10 1.22 1.53 3.95 5.43 2.50 3.85 3.14 1.09 -1.83 2.57 3.93 2.62 0.35 -1.68
Nuclear Periphery 0.53 -10.41 -4.05 -4.48 0.70 -8.94 -6.33 -21.99 -17.48 0.08 -2.31 -15.49 -17.82 -19.20 -0.08
Nuclear Periphery Foci -3.25 -0.70 3.75 8.73 5.45 1.47 7.56 6.75 6.82 -3.20 -0.77 2.37 7.07 12.12 5.28
Nucleolus -1.98 5.61 8.49 14.43 8.48 1.85 8.92 6.85 1.70 -17.80 1.73 9.37 6.82 2.20 -12.93
Nucleus -0.60 1.54 2.97 1.85 3.08 0.93 5.00 3.30 0.73 -6.01 0.84 4.99 2.36 0.46 -5.26
Peroxisomes -3.93 -0.51 4.80 6.06 3.47 -2.47 8.75 -11.21 -10.61 -11.84 -4.63 0.09 -11.23 -10.30 -11.13
Vacuole 17.89 16.38 5.40 -3.16 -2.60 16.15 3.16 24.73 4.36 8.55 24.01 17.47 30.21 4.77 6.16
Vacuole Periphery -4.43 6.82 15.37 22.59 12.75 10.01 18.28 22.19 19.50 3.57 5.32 16.83 26.03 29.23 12.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication
Localization
Cell Percentages ER (72%)
Cell Cycle Regulation No
Subcompartmental Group ER-4

Pmp2

Pmp2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pmp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available