| ORF | |
|---|---|
| Human Ortholog | |
| Description | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 1 | 0 | 1 | – | 0 | 0 |
| Bud | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 1 | 0 | 0 | – | 0 | 0 |
| Bud Neck | 1 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 1 | 0 | 0 | 5 | 0 | 1 | – | 0 | 0 |
| Bud Site | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 0 | 0 | 0 | 0 | – | 0 | 0 |
| Cytoplasm | 214 | 87 | – | – | – | – | – | – | – | – | – | – | – | – | – | 95 | 118 | 75 | 158 | 87 | 113 | – | 0 | 0 |
| Endoplasmic Reticulum | 1 | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | 8 | 12 | 6 | 9 | 0 | 4 | – | 0 | 0 |
| Endosome | 60 | 2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 10 | 24 | 18 | 59 | 3 | 10 | – | 0 | 0 |
| Golgi | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 0 | 2 | 1 | 0 | – | 0 | 0 |
| Mitochondria | 12 | 31 | – | – | – | – | – | – | – | – | – | – | – | – | – | 5 | 3 | 2 | 49 | 12 | 45 | – | 0 | 0 |
| Nucleus | 20 | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | 5 | 3 | 1 | 31 | 3 | 6 | – | 0 | 0 |
| Nuclear Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 5 | 0 | 0 | – | 0 | 0 |
| Nucleolus | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 13 | 1 | 0 | – | 0 | 0 |
| Peroxisomes | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 1 | 0 | 0 | – | 0 | 0 |
| SpindlePole | 3 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 1 | 1 | 2 | 66 | 6 | 21 | – | 0 | 0 |
| Vac/Vac Membrane | 104 | 8 | – | – | – | – | – | – | – | – | – | – | – | – | – | 31 | 39 | 31 | 97 | 12 | 47 | – | 0 | 0 |
| Unique Cell Count | 364 | 119 | 139 | 172 | 114 | 527 | 136 | 269 | 2 | 2 | ||||||||||||||
| Labelled Cell Count | 415 | 130 | 156 | 202 | 135 | 527 | 136 | 269 | 2 | 2 | ||||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 4.8 | 3.5 | – | – | – | – | – | – | – | – | – | – | – | – | – | 5.3 | 5.9 | 6.1 | – | – | – |
| Std Deviation (1e-4) | 0.8 | 1.6 | – | – | – | – | – | – | – | – | – | – | – | – | – | 1.4 | 2.0 | 1.7 | – | – | – |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | -0.5566 | 0.3072 | 0.0572 | 0.096 | -0.3867 | 0.3309 | 0.9887 | 1.093 | 1.0049 | 0.7948 | 0.8914 | 0.8986 | 0.8728 | 0.9269 | 0.6492 | 0.419 | 0.6388 | 0.6343 |
| Actin | 0.0011 | 0.0002 | 0.0005 | 0.0009 | 0.0006 | 0.0004 | 0.0389 | 0.0001 | 0.0053 | 0.0032 | 0.0116 | 0.0023 | 0.0375 | 0.0012 | 0.0004 | 0.0005 | 0.0013 | 0.0044 |
| Bud | 0.0005 | 0.0003 | 0.0003 | 0.0002 | 0.0004 | 0.0003 | 0.0006 | 0.0001 | 0.0004 | 0.001 | 0.0006 | 0.0004 | 0.0003 | 0.0004 | 0.0004 | 0.0002 | 0.0072 | 0.0004 |
| Bud Neck | 0.0102 | 0.0028 | 0.0055 | 0.0041 | 0.0203 | 0.0266 | 0.0039 | 0.0022 | 0.0044 | 0.0133 | 0.004 | 0.0147 | 0.002 | 0.0013 | 0.0017 | 0.0051 | 0.0063 | 0.0106 |
| Bud Periphery | 0.0005 | 0.0003 | 0.0004 | 0.0003 | 0.0008 | 0.0004 | 0.001 | 0.0002 | 0.0006 | 0.0013 | 0.0009 | 0.0007 | 0.0004 | 0.0004 | 0.0004 | 0.0005 | 0.0036 | 0.0007 |
| Bud Site | 0.0157 | 0.0152 | 0.0099 | 0.0035 | 0.0018 | 0.0027 | 0.0079 | 0.0041 | 0.0071 | 0.0286 | 0.0017 | 0.0031 | 0.0029 | 0.0282 | 0.0023 | 0.0049 | 0.0027 | 0.0017 |
| Cell Periphery | 0.0006 | 0.0009 | 0.001 | 0.0005 | 0.0004 | 0.0005 | 0.0003 | 0.0005 | 0.0004 | 0.0006 | 0.0001 | 0.0003 | 0.0005 | 0.0005 | 0.0003 | 0.0016 | 0.0007 | 0.0003 |
| Cytoplasm | 0.2289 | 0.2762 | 0.2016 | 0.2002 | 0.2074 | 0.3039 | 0.1338 | 0.1717 | 0.1377 | 0.1471 | 0.1795 | 0.1941 | 0.0998 | 0.1165 | 0.1137 | 0.1154 | 0.1804 | 0.1125 |
| Cytoplasmic Foci | 0.0341 | 0.0266 | 0.028 | 0.0285 | 0.0111 | 0.029 | 0.0391 | 0.0304 | 0.0417 | 0.0608 | 0.0257 | 0.0418 | 0.0952 | 0.0162 | 0.0463 | 0.0145 | 0.0357 | 0.0394 |
| Eisosomes | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0.0004 | 0.0002 | 0.0002 | 0.0001 | 0.0002 | 0.0002 |
| Endoplasmic Reticulum | 0.0206 | 0.016 | 0.0168 | 0.0112 | 0.0142 | 0.0128 | 0.0043 | 0.0046 | 0.0061 | 0.0042 | 0.0047 | 0.0056 | 0.0084 | 0.0062 | 0.0065 | 0.0068 | 0.0114 | 0.0052 |
| Endosome | 0.0321 | 0.0303 | 0.0391 | 0.0442 | 0.0155 | 0.0185 | 0.0264 | 0.0166 | 0.0485 | 0.0406 | 0.0311 | 0.0349 | 0.0478 | 0.0339 | 0.0446 | 0.0253 | 0.0602 | 0.0255 |
| Golgi | 0.0008 | 0.0008 | 0.001 | 0.0009 | 0.0005 | 0.0004 | 0.0074 | 0.0004 | 0.0058 | 0.019 | 0.0156 | 0.0024 | 0.0138 | 0.0061 | 0.0018 | 0.0008 | 0.0169 | 0.0025 |
| Lipid Particles | 0.0077 | 0.0092 | 0.0111 | 0.009 | 0.0024 | 0.0045 | 0.0346 | 0.0063 | 0.0203 | 0.0223 | 0.0048 | 0.0122 | 0.0308 | 0.0056 | 0.0275 | 0.0112 | 0.0286 | 0.0112 |
| Mitochondria | 0.001 | 0.0008 | 0.0013 | 0.0011 | 0.0424 | 0.0016 | 0.0044 | 0.0007 | 0.0136 | 0.0057 | 0.0058 | 0.0077 | 0.0064 | 0.0079 | 0.0113 | 0.0012 | 0.0132 | 0.004 |
| None | 0.4235 | 0.2445 | 0.352 | 0.3579 | 0.2692 | 0.2117 | 0.4937 | 0.5466 | 0.4231 | 0.212 | 0.4305 | 0.3238 | 0.4583 | 0.5557 | 0.5096 | 0.5556 | 0.421 | 0.4472 |
| Nuclear Periphery | 0.0158 | 0.0247 | 0.0194 | 0.0242 | 0.0171 | 0.0109 | 0.0138 | 0.0067 | 0.0199 | 0.0186 | 0.0203 | 0.0165 | 0.0103 | 0.0156 | 0.0162 | 0.0119 | 0.0271 | 0.0152 |
| Nucleolus | 0.0233 | 0.0138 | 0.0528 | 0.0358 | 0.0266 | 0.0188 | 0.013 | 0.0176 | 0.0437 | 0.078 | 0.0127 | 0.0297 | 0.0074 | 0.0258 | 0.022 | 0.0624 | 0.0311 | 0.0243 |
| Nucleus | 0.1176 | 0.2758 | 0.1841 | 0.1969 | 0.3218 | 0.309 | 0.0591 | 0.1294 | 0.1291 | 0.1774 | 0.1575 | 0.1966 | 0.0823 | 0.1377 | 0.1156 | 0.0854 | 0.1014 | 0.1794 |
| Peroxisomes | 0.0009 | 0.0004 | 0.0006 | 0.0008 | 0.0008 | 0.0005 | 0.0267 | 0.0004 | 0.0068 | 0.0137 | 0.0016 | 0.0038 | 0.0358 | 0.0009 | 0.0184 | 0.0014 | 0.005 | 0.002 |
| Punctate Nuclear | 0.0482 | 0.0376 | 0.0422 | 0.0499 | 0.0355 | 0.034 | 0.0823 | 0.0471 | 0.0697 | 0.1417 | 0.0859 | 0.0957 | 0.0464 | 0.0209 | 0.0432 | 0.0598 | 0.0325 | 0.1032 |
| Vacuole | 0.0158 | 0.0224 | 0.0305 | 0.028 | 0.01 | 0.0123 | 0.0072 | 0.0134 | 0.0139 | 0.0091 | 0.0036 | 0.0124 | 0.0122 | 0.0175 | 0.0154 | 0.0343 | 0.0107 | 0.0089 |
| Vacuole Periphery | 0.0008 | 0.0011 | 0.0015 | 0.0016 | 0.0013 | 0.0008 | 0.0012 | 0.0007 | 0.0018 | 0.0016 | 0.0016 | 0.0013 | 0.0011 | 0.0013 | 0.0022 | 0.001 | 0.0027 | 0.0009 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 7.8881 | 9.402 | 9.2338 | 15.2435 | 10.0267 | 10.2025 | 13.4906 | 12.9266 | 12.8549 | 15.2947 |
| Translational Efficiency | 0.2939 | 0.2253 | 0.3141 | 0.2349 | 0.2262 | 0.2476 | 0.2614 | 0.2645 | 0.2436 | 0.1701 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | ✘ |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 1843 | 23 | 649 | 778 | 1644 | 2211 | 792 | 1385 | 3487 | 2234 | 1441 | 2163 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 630.56 | 787.76 | 923.73 | 839.97 | 625.96 | 706.09 | 821.62 | 817.86 | 628.39 | 706.93 | 867.61 | 825.81 |
| Standard Deviation | 69.53 | 99.21 | 103.88 | 107.60 | 79.59 | 90.04 | 109.54 | 96.86 | 74.47 | 90.51 | 118.48 | 101.41 |
| Intensity Change Log 2 | — | 0.321123 | 0.550838 | 0.413704 | — | 0.173782 | 0.392401 | 0.385783 | — | 0.249602 | 0.474083 | 0.399862 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000018 | 0.000295 | 0.000555 | 0.000482 | 0.000038 | 0.000245 | 0.000235 | 0.000329 | 0.000027 | 0.000246 | 0.000379 | 0.000384 |
| Bud Neck | 0.002421 | 0.001935 | 0.008026 | 0.027211 | 0.006253 | 0.024440 | 0.002428 | 0.008634 | 0.004227 | 0.024209 | 0.004949 | 0.015316 |
| Bud Site | 0.000821 | 0.001201 | 0.006759 | 0.033906 | 0.001015 | 0.007470 | 0.002724 | 0.009168 | 0.000912 | 0.007406 | 0.004541 | 0.018066 |
| Cell Periphery | 0.000082 | 0.000193 | 0.000199 | 0.000201 | 0.000097 | 0.000151 | 0.000648 | 0.000145 | 0.000089 | 0.000152 | 0.000446 | 0.000165 |
| Cytoplasm | 0.565827* | 0.265663* | 0.074857 | 0.183282* | 0.374557* | 0.348712* | 0.124754* | 0.181481* | 0.475650* | 0.347857* | 0.102282* | 0.182129* |
| Cytoplasmic Foci | 0.060767 | 0.208921* | 0.002826 | 0.004989 | 0.098099 | 0.134793 | 0.008215 | 0.005616 | 0.078368 | 0.135557 | 0.005788 | 0.005390 |
| Eisosomes | 0.000035 | 0.000166 | 0.000049 | 0.000036 | 0.000058 | 0.000077 | 0.000538 | 0.000041 | 0.000046 | 0.000078 | 0.000318 | 0.000039 |
| Endoplasmic Reticulum | 0.000238 | 0.002413 | 0.008345 | 0.006276 | 0.001064 | 0.001522 | 0.002518 | 0.006140 | 0.000627 | 0.001531 | 0.005142 | 0.006189 |
| Endosome | 0.000991 | 0.012973 | 0.001636 | 0.007868 | 0.002620 | 0.009652 | 0.001441 | 0.002410 | 0.001759 | 0.009687 | 0.001529 | 0.004373 |
| Golgi | 0.000181 | 0.001222 | 0.000079 | 0.003187 | 0.000407 | 0.002611 | 0.001261 | 0.000154 | 0.000288 | 0.002597 | 0.000729 | 0.001245 |
| Lipid Particles | 0.001786 | 0.021199 | 0.001490 | 0.001133 | 0.009680 | 0.011053 | 0.001945 | 0.001391 | 0.005508 | 0.011157 | 0.001740 | 0.001298 |
| Mitochondria | 0.000994 | 0.001407 | 0.001022 | 0.003991 | 0.005659 | 0.015721 | 0.001332 | 0.002427 | 0.003193 | 0.015574 | 0.001192 | 0.002990 |
| Mitotic Spindle | 0.000343 | 0.000085 | 0.000645 | 0.052127 | 0.000428 | 0.012397 | 0.004450 | 0.016076 | 0.000383 | 0.012270 | 0.002736 | 0.029043 |
| None | 0.021734 | 0.003130 | 0.004600 | 0.007067 | 0.009108 | 0.005637 | 0.025069 | 0.005490 | 0.015781 | 0.005611 | 0.015850 | 0.006058 |
| Nuclear Periphery | 0.000224 | 0.001299 | 0.002101 | 0.004279 | 0.001731 | 0.002865 | 0.001453 | 0.005312 | 0.000935 | 0.002848 | 0.001744 | 0.004940 |
| Nuclear Periphery Foci | 0.000198 | 0.003041 | 0.001080 | 0.002164 | 0.000804 | 0.000678 | 0.000572 | 0.002191 | 0.000484 | 0.000703 | 0.000801 | 0.002182 |
| Nucleolus | 0.001528 | 0.006144 | 0.003067 | 0.002266 | 0.003535 | 0.005315 | 0.003598 | 0.003274 | 0.002474 | 0.005323 | 0.003359 | 0.002912 |
| Nucleus | 0.334055* | 0.348998* | 0.858763* | 0.594132* | 0.470259* | 0.369667* | 0.799182* | 0.708553* | 0.398271* | 0.369454* | 0.826016* | 0.667398* |
| Peroxisomes | 0.000371 | 0.037853 | 0.000363 | 0.002434 | 0.002463 | 0.009450 | 0.002896 | 0.000620 | 0.001357 | 0.009742 | 0.001755 | 0.001272 |
| Vacuole | 0.007178 | 0.081008 | 0.023213 | 0.060434 | 0.011714 | 0.035766 | 0.014596 | 0.040062 | 0.009317 | 0.036231 | 0.018477 | 0.047390 |
| Vacuole Periphery | 0.000209 | 0.000854 | 0.000326 | 0.002534 | 0.000410 | 0.001778 | 0.000145 | 0.000485 | 0.000304 | 0.001769 | 0.000226 | 0.001222 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -2.57 | -11.06 | -14.28 | -3.98 | 0.28 | -4.23 | -9.58 | -14.67 | -5.10 | -4.37 | -4.55 | -14.14 | -20.54 | -6.91 | -1.67 |
| Bud Neck | 0.88 | -4.06 | -7.75 | -7.90 | -3.63 | -10.26 | 3.88 | -4.83 | 7.23 | -9.24 | -11.99 | -2.14 | -9.95 | 5.41 | -6.69 |
| Bud Site | -1.32 | -4.05 | -6.18 | -5.97 | -3.19 | -6.73 | -1.73 | -5.70 | 0.09 | -2.96 | -7.05 | -4.23 | -8.41 | -2.25 | -4.02 |
| Cell Periphery | -3.01 | -3.20 | -3.37 | 1.67 | 1.68 | -1.68 | -1.53 | -1.77 | 0.60 | 1.40 | -2.22 | -1.93 | -3.66 | 0.62 | 1.61 |
| Cytoplasm | 6.23 | 68.32* | 52.55 | 2.57 | -7.74 | 3.07 | 28.25 | 28.18 | 27.02 | -3.54 | 18.27 | 61.81 | 56.49 | 30.38 | -7.73 |
| Cytoplasmic Foci | -4.48 | 26.26 | 26.08 | 6.23 | -0.91 | -6.73 | 24.45 | 25.65 | 33.86 | 2.02 | -13.15 | 34.03 | 35.14 | 34.58 | 1.20 |
| Eisosomes | -4.87 | -6.57 | -9.58 | 3.75 | 0.34 | -3.44 | -1.75 | -1.17 | 2.54 | 1.72 | -6.69 | -1.92 | -7.43 | 2.69 | 1.73 |
| Endoplasmic Reticulum | -3.23 | -15.74 | -18.74 | -9.09 | 0.17 | -1.87 | -9.41 | -20.02 | -18.98 | -13.12 | -4.73 | -18.02 | -28.05 | -23.46 | -7.11 |
| Endosome | -3.35 | -5.23 | -3.73 | 2.60 | -1.70 | -9.53 | 2.68 | -0.49 | 9.59 | -3.68 | -11.66 | -1.07 | -4.14 | 8.99 | -3.39 |
| Golgi | -1.28 | 1.78 | -1.19 | 0.36 | -1.29 | -5.09 | -0.58 | 4.48 | 5.77 | 0.94 | -5.43 | -0.57 | -0.49 | 4.74 | 0.32 |
| Lipid Particles | -1.85 | -0.34 | 1.65 | 1.88 | 2.02 | -1.02 | 7.76 | 8.14 | 13.13 | 0.81 | -6.56 | 7.28 | 8.12 | 13.46 | 1.63 |
| Mitochondria | -0.91 | -0.27 | -4.55 | -2.27 | -3.97 | -5.97 | 3.70 | 2.95 | 10.68 | -1.43 | -9.39 | 3.48 | 1.65 | 10.91 | -2.80 |
| Mitotic Spindle | 0.93 | -1.71 | -8.10 | -8.15 | -7.79 | -7.05 | -2.67 | -6.94 | -2.10 | -4.19 | -7.07 | -3.10 | -10.61 | -5.34 | -8.72 |
| None | 10.33 | 11.91 | 9.74 | -2.94 | -3.24 | 2.67 | -2.94 | 3.72 | 1.16 | 4.36 | 9.17 | 1.59 | 10.72 | 0.05 | 3.63 |
| Nuclear Periphery | -3.52 | -13.68 | -17.64 | -11.47 | -10.43 | -2.26 | -0.95 | -11.77 | -7.51 | -12.04 | -4.15 | -9.59 | -19.09 | -8.43 | -15.19 |
| Nuclear Periphery Foci | -2.14 | -7.09 | -6.68 | 0.43 | -1.54 | 0.67 | 0.04 | -3.57 | -4.68 | -4.13 | -0.56 | -3.01 | -5.63 | -5.78 | -4.24 |
| Nucleolus | -1.79 | -3.47 | -2.78 | 1.03 | 1.40 | -2.38 | -0.90 | -0.75 | 1.41 | 0.30 | -5.00 | -3.10 | -2.66 | 2.25 | 0.97 |
| Nucleus | -0.18 | -52.49 | -21.77 | -4.62 | 17.20 | 10.95 | -29.46 | -21.33 | -33.01 | 9.78 | 3.87 | -55.70 | -33.48 | -33.17 | 18.38 |
| Peroxisomes | -1.19 | -1.22 | -1.49 | 1.18 | -1.12 | -9.66 | 0.59 | 8.13 | 12.71 | 1.61 | -11.16 | 0.16 | 4.40 | 12.06 | 1.31 |
| Vacuole | -3.53 | -8.41 | -17.20 | -1.83 | -12.31 | -13.76 | -5.55 | -17.99 | -11.26 | -13.00 | -16.16 | -10.16 | -24.91 | -16.17 | -17.46 |
| Vacuole Periphery | -2.99 | -1.73 | -1.70 | 0.41 | -1.26 | -7.52 | 5.23 | 0.97 | 7.73 | -2.75 | -8.36 | 1.61 | -1.44 | 6.11 | -1.97 |
| ORF | |
|---|---|
| Human Ortholog | |
| Description | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus |
| Localization | |
| Cell Percentages | cytoplasm (35%), nucleus (9%), mixed (44%) |
| Cell Cycle Regulation | Yes |
| cytoplasm - MA (4.1e-10) | |
| nucleus - T/G1 (0.00016) | |
| Subcompartmental Group | N/A |
YEL025C
YEL025C
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Yel025c-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
