Standard name
Human Ortholog
Description Protein with sequence similarity to acireductone synthases; involved in methionine salvage; found in both the cytoplasm and nucleus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.95 0.98 0.97 0.94 0.88 0.76 0.8 0.77 0.72 0.68 0.65 0.61 0.99 0.99 0.99 0.64 0.67 0.69 0.92 0.93 0.94 0.93 0.92 0.89
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.07 0.1 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.17 0 0 0.15 0.13 0.17 0.16 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.06 0.11 0.14 0.21 0.19 0.19 0.2 0.24 0.26 0 0 0 0.26 0.29 0.22 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 1 0 3 0 0 0 0 6 4 8 0 4 4 2 3 5
Bud 0 0 0 0 0 7 1 2 4 3 8 5 0 0 0 0 0 0 0 0 4 2 3 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 3 10 4 11 3 9 18 13 12 21 20 0 2 3 9 8 6 0 0 0 0 0 0
Cytoplasm 293 665 700 420 553 421 598 731 604 511 562 548 493 587 619 275 215 159 284 648 682 372 539 567
Endoplasmic Reticulum 2 3 2 4 4 3 2 7 3 10 8 5 2 3 0 15 11 10 1 2 4 2 8 7
Endosome 1 0 0 1 0 0 1 0 2 2 3 2 1 1 0 37 24 24 5 10 7 2 5 14
Golgi 1 3 3 1 1 0 1 1 0 0 0 0 0 0 1 16 24 8 4 4 2 3 2 3
Mitochondria 2 5 0 3 6 92 9 23 128 97 142 140 0 0 0 17 9 2 0 6 3 2 5 4
Nucleus 4 2 4 3 12 8 26 44 12 24 21 35 1 3 1 8 6 6 0 2 0 1 1 3
Nuclear Periphery 1 0 0 0 0 1 0 0 3 2 0 2 0 0 0 0 0 0 2 0 1 0 0 1
Nucleolus 1 1 0 0 0 1 0 2 0 2 2 1 0 0 1 6 8 3 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 1 0 1 0 0 1 1 0 0 1 0 0 0 16 14 9 2 2 5 0 1 6
Vac/Vac Membrane 6 4 23 26 70 77 160 182 156 151 204 231 2 5 2 112 94 52 2 4 1 2 6 8
Unique Cell Count 307 678 721 449 627 557 749 949 839 748 860 903 497 595 624 428 322 232 308 694 728 398 586 638
Labelled Cell Count 313 686 744 462 658 613 807 1011 927 814 974 991 499 601 627 517 417 287 308 694 728 398 586 638


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.9 7.1 8.9 8.4 8.9 6.3 7.9 8.3 7.3 7.4 7.4 7.3 9.0 9.5 9.8 15.1 16.4 14.0 7.6 8.4 8.3
Std Deviation (1e-4) 1.3 1.0 1.2 1.5 1.3 1.8 1.5 1.5 1.4 1.4 1.4 1.4 1.5 1.7 1.6 4.4 4.4 4.1 1.4 1.6 1.5
Intensity Change (Log2) – – – -0.08 0.01 -0.5 -0.16 -0.1 -0.28 -0.25 -0.25 -0.28 0.02 0.1 0.14 0.77 0.89 0.66 -0.22 -0.09 -0.09

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.8 0.5 -1.5 -0.3 0.8 0.3 0.3 1.5 1.2 0 -2.0 -1.7 0.9 1.3 0
Cytoplasm -2.9 -6.4 -11.6 -10.3 -11.6 -13.3 -14.5 -15.7 -17.3 2.5 1.9 2.8 -15.0 -13.8 -12.7
Endoplasmic Reticulum 0 0 0 0 0 0 2.3 0 0 0 0 0 4.4 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 8.0 7.4 8.7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 4.3 6.6 0
Mitochondria 0 0 11.3 0 4.2 10.9 10.0 11.4 11.1 0 0 0 5.4 0 0
Nucleus 0 2.3 1.6 4.0 4.9 1.7 3.7 3.0 4.3 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 4.9 0 0
Vacuole 2.2 5.8 7.0 10.5 9.9 9.5 10.1 11.6 12.3 -3.4 -2.9 -3.9 11.7 12.3 9.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.6601 3.9163 3.0161 2.9141 2.616 3.1746 6.5856 7.7912 7.1366 6.5242 6.5589 7.0737 6.9399 8.4541 7.5787 7.0941 7.4365 7.8864
Actin 0.0034 0.0012 0.0014 0.0002 0.0001 0.0011 0.0174 0.0034 0.0052 0.025 0.0098 0.0094 0.0008 0.0003 0.0004 0.0002 0.0003 0.0005
Bud 0.0018 0.0036 0.0002 0.0001 0.0001 0.0002 0.0164 0.0271 0.0156 0.0038 0.0189 0.0105 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Bud Neck 0.0003 0.001 0.0003 0.0006 0.0005 0.0011 0.0037 0.0008 0.0066 0.0022 0.0016 0.0093 0.0002 0.0001 0.0002 0.0003 0.0004 0.0007
Bud Periphery 0.0006 0.0009 0.0001 0 0 0.0001 0.0084 0.006 0.0062 0.0022 0.0055 0.007 0 0 0 0 0 0
Bud Site 0.0027 0.0106 0.0004 0.0001 0.0001 0.0005 0.0165 0.0321 0.0209 0.0101 0.0068 0.0037 0.0002 0.0003 0.0002 0.0002 0.0001 0.0001
Cell Periphery 0.0001 0.0001 0 0 0 0 0.0005 0.0003 0.0004 0.0001 0.0004 0.0001 0 0 0 0 0 0
Cytoplasm 0.8892 0.9205 0.8887 0.889 0.9277 0.9139 0.7908 0.8645 0.8131 0.7774 0.7829 0.8159 0.8863 0.9431 0.9351 0.9018 0.9649 0.9333
Cytoplasmic Foci 0.009 0.0121 0.0067 0.0078 0.0076 0.0104 0.0208 0.0087 0.0135 0.0243 0.024 0.0247 0.0038 0.002 0.0036 0.0018 0.0032 0.0045
Eisosomes 0 0 0 0 0 0 0.0001 0 0.0001 0.0002 0.0002 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0038 0.0021 0.0027 0.0026 0.0017 0.0032 0.0048 0.0018 0.0057 0.0034 0.0031 0.002 0.0034 0.0019 0.0023 0.0022 0.0017 0.0013
Endosome 0.0067 0.0047 0.0042 0.0069 0.0106 0.0067 0.0172 0.0026 0.0154 0.0235 0.017 0.0087 0.0018 0.0007 0.0017 0.0008 0.0015 0.0016
Golgi 0.0005 0.0005 0.0002 0.0001 0.0002 0.0001 0.0041 0.0003 0.0034 0.0096 0.0049 0.0023 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001
Lipid Particles 0.0002 0.0002 0.0001 0 0 0.0001 0.0034 0.0001 0.0034 0.0037 0.0188 0.0057 0.0001 0 0 0 0 0
Mitochondria 0.0003 0.0003 0.0002 0.0002 0.0003 0.0002 0.0021 0.0008 0.0062 0.0058 0.0155 0.0008 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
None 0.0701 0.021 0.0721 0.0565 0.0396 0.0343 0.0519 0.0193 0.038 0.0594 0.0145 0.0377 0.0933 0.0472 0.0486 0.0625 0.0214 0.0511
Nuclear Periphery 0.002 0.0033 0.002 0.0025 0.001 0.003 0.0067 0.003 0.0061 0.0061 0.0182 0.0042 0.0013 0.0007 0.0008 0.0015 0.0007 0.0006
Nucleolus 0.0001 0.0006 0.0001 0.0001 0 0.0002 0.0004 0.0004 0.0006 0.0006 0.0017 0.0006 0 0 0 0 0 0
Nucleus 0.0061 0.0102 0.0174 0.0297 0.0074 0.0178 0.0184 0.017 0.0209 0.0129 0.0277 0.024 0.0068 0.0026 0.0054 0.0272 0.0045 0.0048
Peroxisomes 0.0004 0.0004 0.0002 0.0001 0 0.0002 0.0035 0.0008 0.0045 0.0072 0.0133 0.0073 0.0001 0 0.0001 0 0 0.0001
Punctate Nuclear 0.0014 0.0052 0.0015 0.0012 0.0006 0.0053 0.0101 0.0098 0.0112 0.02 0.0125 0.0242 0.0008 0.0005 0.0005 0.0006 0.0004 0.0005
Vacuole 0.0013 0.0014 0.0011 0.0018 0.0021 0.0014 0.0022 0.001 0.0024 0.002 0.0017 0.0014 0.0005 0.0003 0.0005 0.0004 0.0003 0.0004
Vacuole Periphery 0.0002 0.0003 0.0002 0.0003 0.0003 0.0003 0.0006 0.0002 0.0006 0.0006 0.0011 0.0003 0.0001 0 0.0001 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.2344 40.378 59.9244 66.015 56.4715 49.9804 43.3778 59.0462 69.0918 57.1187
Translational Efficiency 0.7034 1.1841 0.9492 0.9853 0.9848 0.7452 1.0436 0.8811 0.9536 0.9209

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1413 485 2864 2027 1058 2610 2011 994 2471 3095 4875 3021

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 797.64 980.55 980.40 986.40 801.51 938.38 926.16 1007.16 799.30 944.99 958.03 993.23
Standard Deviation 105.85 130.03 128.86 142.04 104.65 121.43 124.68 145.53 105.35 123.77 129.93 143.53
Intensity Change Log 2 — 0.297853 0.297633 0.306435 — 0.227452 0.208541 0.329500 — 0.262997 0.253667 0.318042

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000245 0.000278 0.000171 0.002541 0.000327 0.000238 0.000092 0.002635 0.000280 0.000245 0.000139 0.002572
Bud Neck 0.003680 0.002399 0.005159 0.009024 0.001547 0.004409 0.003687 0.003654 0.002767 0.004094 0.004552 0.007257
Bud Site 0.005839 0.011361 0.014703 0.051701 0.003649 0.008474 0.007850 0.051079 0.004901 0.008926 0.011876 0.051496
Cell Periphery 0.000119 0.000106 0.000066 0.000108 0.000092 0.000046 0.000051 0.000158 0.000108 0.000055 0.000060 0.000125
Cytoplasm 0.677375 0.718749 0.689245 0.565596 0.729071 0.785837 0.745112 0.647652 0.699510 0.775324 0.712291 0.592595
Cytoplasmic Foci 0.143469 0.119956 0.005582 0.018196 0.088920 0.049096 0.010730 0.020182 0.120113 0.060200 0.007705 0.018850
Eisosomes 0.000064 0.000031 0.000009 0.000020 0.000036 0.000017 0.000012 0.000026 0.000052 0.000019 0.000010 0.000022
Endoplasmic Reticulum 0.001238 0.001022 0.000558 0.000886 0.000850 0.000366 0.000383 0.000718 0.001072 0.000468 0.000486 0.000831
Endosome 0.005507 0.006754 0.000608 0.008767 0.005089 0.002842 0.001583 0.006368 0.005328 0.003455 0.001010 0.007978
Golgi 0.002092 0.001696 0.000057 0.006200 0.000460 0.001159 0.000786 0.004618 0.001393 0.001243 0.000358 0.005680
Lipid Particles 0.002270 0.001073 0.000238 0.001356 0.001968 0.000477 0.000328 0.000695 0.002141 0.000570 0.000275 0.001139
Mitochondria 0.002374 0.000118 0.000598 0.003688 0.001077 0.001058 0.000776 0.008832 0.001819 0.000910 0.000671 0.005380
Mitotic Spindle 0.001410 0.001902 0.008135 0.144764 0.001934 0.007669 0.017658 0.034042 0.001634 0.006765 0.012064 0.108333
None 0.002830 0.002081 0.005884 0.006285 0.004089 0.004698 0.006991 0.006213 0.003369 0.004288 0.006340 0.006261
Nuclear Periphery 0.000180 0.000180 0.000594 0.000887 0.000229 0.000170 0.000499 0.000493 0.000201 0.000172 0.000555 0.000758
Nuclear Periphery Foci 0.001076 0.003092 0.000307 0.001196 0.001822 0.000322 0.000681 0.001795 0.001396 0.000756 0.000461 0.001393
Nucleolus 0.000667 0.000283 0.000156 0.000549 0.000436 0.000377 0.000232 0.000191 0.000568 0.000362 0.000187 0.000431
Nucleus 0.091908 0.061959 0.241671 0.102483 0.106399 0.085330 0.143493 0.095594 0.098113 0.081668 0.201172 0.100216
Peroxisomes 0.001490 0.001218 0.000210 0.002524 0.001338 0.001805 0.000360 0.002232 0.001425 0.001713 0.000272 0.002428
Vacuole 0.054663 0.065409 0.025911 0.070780 0.050380 0.045239 0.057946 0.110394 0.052829 0.048400 0.039126 0.083814
Vacuole Periphery 0.001503 0.000336 0.000136 0.002447 0.000287 0.000371 0.000751 0.002430 0.000982 0.000366 0.000390 0.002441

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.62 0.14 -4.01 -3.74 -3.89 0.47 1.25 -1.42 -1.95 -2.46 0.42 1.17 -3.54 -4.10 -4.66
Bud Neck 3.10 -2.16 -3.64 -5.89 -1.25 -6.00 -4.15 -4.79 1.98 0.04 -3.20 -3.92 -5.50 -1.58 -1.46
Bud Site -2.54 -4.95 -7.08 -2.79 -2.63 -3.97 -2.10 -5.39 -3.50 -4.52 -4.06 -5.38 -9.04 -5.69 -5.08
Cell Periphery 1.27 5.36 5.38 3.92 -0.20 6.27 5.92 0.51 -3.75 -3.55 8.71 7.55 4.58 -4.25 -2.98
Cytoplasm -2.97 5.89 18.69 16.41 15.29 -7.29 5.14 19.06 27.81 16.42 -12.43 7.91 26.92 40.87 22.56
Cytoplasmic Foci 3.09 32.13 30.46 15.68 -7.31 9.60 20.05 17.70 15.23 -5.57 17.22 37.27 34.83 23.83 -8.52
Eisosomes 3.12 5.04 4.17 2.97 -8.11 7.77 9.19 1.68 -8.24 -10.37 5.61 6.64 4.60 -5.46 -12.99
Endoplasmic Reticulum 1.16 3.30 4.02 1.81 1.40 2.71 2.76 -0.56 -4.11 -6.99 4.44 4.22 2.81 -2.88 -1.84
Endosome -1.07 11.70 4.45 3.66 -5.71 4.27 7.55 3.64 -0.07 -3.70 4.87 13.68 5.62 1.15 -6.61
Golgi 0.49 6.16 1.32 0.17 -3.09 -2.20 0.14 -1.16 0.27 -1.11 0.61 5.50 0.40 -0.14 -3.10
Lipid Particles 4.87 8.78 3.81 -1.07 -6.12 3.50 3.60 1.76 -7.50 -10.07 6.90 7.91 3.67 -5.79 -8.34
Mitochondria 3.16 2.43 1.27 -6.39 -3.63 0.04 0.81 -0.77 -0.88 -1.36 1.67 2.48 0.33 -1.58 -2.69
Mitotic Spindle -0.50 -5.48 -14.98 -14.50 -13.22 -3.64 -6.14 -7.33 -5.54 -3.48 -4.25 -8.18 -16.52 -14.15 -13.19
None 1.94 -6.94 -9.90 -14.30 -5.75 -0.62 -2.42 -2.72 -2.83 -0.12 -1.44 -5.51 -8.37 -6.31 -3.88
Nuclear Periphery -0.47 -23.45 -18.41 -18.10 -9.20 1.35 -6.72 -15.38 -16.21 -7.69 0.89 -17.56 -23.13 -22.32 -11.78
Nuclear Periphery Foci -5.20 5.04 -1.30 4.71 -7.47 6.22 4.47 -2.00 -10.01 -7.67 4.61 6.50 -1.73 -7.71 -10.27
Nucleolus 2.79 3.45 -1.05 -3.11 -3.52 0.28 1.30 1.16 1.30 -0.52 1.76 3.61 -0.93 -2.29 -3.50
Nucleus 6.07 -37.15 -14.60 -18.80 22.50 4.83 -14.06 -4.81 -9.63 7.57 5.28 -37.59 -14.53 -20.45 21.64
Peroxisomes 1.27 5.64 2.68 1.63 -3.45 -0.73 2.61 1.26 2.19 -2.48 -0.56 5.48 2.67 2.44 -4.18
Vacuole -2.93 2.48 -25.08 -18.38 -27.21 1.64 -8.93 -23.24 -24.76 -18.48 1.10 -4.54 -33.91 -35.11 -31.60
Vacuole Periphery 2.87 3.36 1.90 -1.11 -1.93 -1.08 -0.90 -0.94 -0.66 -0.39 2.61 3.02 1.34 -1.17 -1.69
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with sequence similarity to acireductone synthases; involved in methionine salvage; found in both the cytoplasm and nucleus
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Utr4

Utr4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Utr4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available