Standard name
Human Ortholog
Description Cytochrome c isoform 2, expressed under hypoxic conditions; also known as iso-2-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; protein abundance increases in response to DNA replication stress; CYC7 has a paralog, CYC1, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.96 0.96 0.91 0.7 0.55 0.56 0.48 0.48 0.41 0.45 0.99 0.99 0.99 0.94 0.91 0.95 0.83 0.86 0.69 0.76 0.77 0.75
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.09 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.05 0.07 0.21 0.49 0.64 0.58 0.68 0.62 0.69 0.69 0 0 0 0 0 0 0.08 0.06 0.15 0.12 0.09 0.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 0.07 0.07 0.13 0.06 0.06 0 0 0 0 0.09 0.05 0 0 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 0 6 3 12 2 3 2
Bud 2 2 1 1 0 5 3 9 10 7 9 14 0 0 0 0 1 0 2 0 1 1 4 3
Bud Neck 1 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 1 1 4 1 5 6
Bud Site 0 0 0 0 0 1 0 0 2 2 1 5 0 0 0 0 0 0
Cell Periphery 1 3 0 2 0 1 1 2 1 1 4 2 4 0 2 1 0 1 3 1 1 1 2 1
Cytoplasm 508 325 311 252 255 273 270 301 210 246 174 216 321 353 430 49 30 35 456 290 233 153 209 216
Endoplasmic Reticulum 1 3 2 1 0 2 2 2 0 1 3 5 2 1 2 3 3 1 0 0 4 1 1 3
Endosome 1 0 0 2 1 3 0 1 4 1 4 2 1 2 0 1 0 0 13 6 6 1 1 1
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0
Mitochondria 4 3 15 19 59 192 311 309 297 316 292 332 0 0 0 0 0 0 43 20 50 23 24 29
Nucleus 0 0 0 1 0 3 4 11 6 6 6 9 1 1 1 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 1 0 0 0 3 1 3 5 4 2 0 1 0 0 0 0 0 1 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 1 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 1 1 1 3 0 3 2 5 2 7 4 9 0 0 0 0 0 0 5 1 4 1 2 1
Vac/Vac Membrane 10 1 4 2 8 13 23 35 32 69 24 28 0 1 2 0 3 2 6 3 5 9 10 12
Unique Cell Count 520 331 325 262 279 388 487 537 435 513 424 484 324 357 434 52 33 37 550 338 336 202 271 287
Labelled Cell Count 529 338 337 284 323 496 619 678 569 661 526 626 330 361 437 55 37 39 550 338 336 202 271 287


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 4.1 3.7 3.9 3.6 3.8 3.1 3.7 3.5 3.4 3.7 3.6 5.5 5.8 5.9 7.4 7.3 6.9 5.5 5.8 5.7
Std Deviation (1e-4) 0.6 0.7 1.2 1.9 1.1 1.3 1.0 1.6 1.1 1.1 1.4 1.1 0.9 1.4 1.4 1.4 1.0 1.1 1.5 1.8 1.6
Intensity Change (Log2) 0.11 -0.01 0.06 -0.23 0.01 -0.07 -0.09 0.02 -0.03 0.6 0.65 0.7 1.01 0.99 0.92 0.58 0.66 0.63


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin
Bud
Bud Neck
Bud Site
Cell Periphery
Cyto
Endoplasmic Reticulum
Endosome
Golgi
Mitochondria
Nuclear Periphery
Nuc
Nucleolus
Peroxisomes
SpindlePole
Vac
Cortical Patches
Cytoplasm
Nucleus
Vacuole

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.4531 2.8928 2.3507 1.5208 1.4527 2.4332 3.5425 4.1328 3.6412 3.0271 3.6484 3.818 2.7456 2.3082 1.7589 1.8047 2.9184 2.0086
Actin 0.0011 0.0008 0.0015 0.0006 0.0007 0.0012 0.0034 0.0007 0.0033 0.001 0.0014 0.0019 0.1069 0.0003 0.0294 0.0177 0.0939 0.025
Bud 0.0039 0.0046 0.0016 0.0022 0.0009 0.0035 0.0015 0.0028 0.0039 0.0027 0.0011 0.0006 0.0007 0.0008 0.0008 0.0006 0.0008 0.0003
Bud Neck 0.0008 0.0005 0.001 0.0006 0.0006 0.0047 0.0004 0.0003 0.0008 0.0005 0.0008 0.0011 0.0015 0.0001 0.0161 0.0004 0.0025 0.0013
Bud Periphery 0.0017 0.0032 0.0015 0.0051 0.0007 0.0018 0.0011 0.0024 0.0057 0.0025 0.0011 0.0005 0.0009 0.0003 0.0007 0.0008 0.0017 0.0006
Bud Site 0.003 0.0135 0.0048 0.0015 0.0003 0.0009 0.0027 0.0032 0.0077 0.0008 0.0007 0.0002 0.0026 0.0008 0.0152 0.0002 0.0017 0.0003
Cell Periphery 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001 0.0002 0.0002 0.0004 0.0001 0.0001 0 0.0004 0.0001 0.0003 0.0001 0.0003 0.0001
Cytoplasm 0.5669 0.6106 0.5456 0.4302 0.4958 0.6102 0.6099 0.6657 0.5439 0.5697 0.682 0.6111 0.4509 0.6631 0.5177 0.5836 0.3916 0.6718
Cytoplasmic Foci 0.0213 0.0179 0.0174 0.0188 0.0182 0.0218 0.0167 0.0088 0.0146 0.0221 0.018 0.0165 0.0167 0.0024 0.0088 0.0224 0.0258 0.0076
Eisosomes 0.0001 0 0.0001 0 0 0 0.0001 0 0.0001 0 0 0 0.0004 0 0.0001 0.0001 0.001 0.0002
Endoplasmic Reticulum 0.0055 0.0031 0.0029 0.0043 0.0025 0.0037 0.0046 0.0028 0.0048 0.0026 0.0033 0.0022 0.0063 0.0022 0.004 0.0061 0.0067 0.0032
Endosome 0.0107 0.006 0.0069 0.006 0.008 0.0113 0.0063 0.0046 0.009 0.0173 0.0106 0.0068 0.0182 0.0006 0.0068 0.0112 0.0528 0.0067
Golgi 0.0005 0.0005 0.0005 0.0004 0.0003 0.0007 0.0006 0.0003 0.0012 0.0007 0.0009 0.0005 0.017 0.0001 0.0068 0.002 0.0387 0.0019
Lipid Particles 0.0006 0.0003 0.0004 0.0003 0.0001 0.0003 0.0003 0.0001 0.0002 0.0002 0.0001 0.0001 0.0113 0.0001 0.0048 0.0067 0.034 0.001
Mitochondria 0.0007 0.0008 0.001 0.0012 0.0009 0.0016 0.0004 0.0009 0.0068 0.0022 0.0008 0.0006 0.0047 0.0001 0.003 0.0014 0.0207 0.0005
None 0.3578 0.3062 0.3913 0.498 0.4534 0.311 0.3435 0.2966 0.3779 0.3636 0.2475 0.3471 0.2731 0.3256 0.3727 0.3062 0.2484 0.2576
Nuclear Periphery 0.0027 0.0022 0.002 0.0024 0.0021 0.0026 0.0014 0.0012 0.0024 0.0022 0.0015 0.0011 0.0123 0.0006 0.0024 0.0044 0.0427 0.0113
Nucleolus 0.0006 0.0006 0.0004 0.0005 0.0004 0.0006 0.0001 0.0002 0.0005 0.0003 0.0004 0.0001 0.0006 0 0.0003 0.0001 0.0019 0.0003
Nucleus 0.0124 0.0202 0.0118 0.0118 0.0068 0.0144 0.0032 0.0061 0.0077 0.0046 0.0135 0.0054 0.0404 0.0018 0.0016 0.0037 0.0062 0.004
Peroxisomes 0.0006 0.0013 0.0007 0.0007 0.0011 0.0008 0.0003 0.0003 0.0007 0.0012 0.0004 0.0009 0.0097 0 0.0033 0.0229 0.0054 0.0005
Punctate Nuclear 0.0036 0.0049 0.006 0.0115 0.003 0.0055 0.0011 0.0009 0.004 0.0023 0.013 0.0017 0.0027 0.0003 0.0036 0.0044 0.0164 0.0043
Vacuole 0.0048 0.0022 0.002 0.0032 0.0032 0.0028 0.0021 0.0019 0.0035 0.0025 0.0024 0.0014 0.0198 0.0006 0.0013 0.0039 0.0033 0.0011
Vacuole Periphery 0.0007 0.0003 0.0003 0.0005 0.0006 0.0006 0.0003 0.0002 0.0007 0.0007 0.0004 0.0003 0.0031 0.0001 0.0003 0.0012 0.0034 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression
Translational Efficiency

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1416 2230 376 154 1813 1786 1393 142 3229 4016 1769 296

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 626.21 729.25 1284.69 886.28 685.60 679.39 793.66 832.53 659.56 707.08 898.03 860.49
Standard Deviation 80.59 87.03 371.49 136.54 86.46 83.43 105.85 107.29 88.96 88.96 280.20 126.27
Intensity Change Log 2 0.219767 1.036702 0.501116 -0.013127 0.211154 0.280135 0.102744 0.663880 0.389851

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000059 0.000499 0.001572 0.001436 0.000095 0.000817 0.000113 0.000151 0.000079 0.000640 0.000423 0.000819
Bud Neck 0.005927 0.045767 0.007249 0.004749 0.016514 0.053653 0.003960 0.000979 0.011871 0.049274 0.004659 0.002940
Bud Site 0.002966 0.019467 0.023766 0.023905 0.004667 0.025921 0.006260 0.001868 0.003921 0.022337 0.009981 0.013333
Cell Periphery 0.000115 0.000195 0.000288 0.000261 0.000118 0.000223 0.000100 0.000289 0.000117 0.000208 0.000140 0.000274
Cytoplasm 0.588747* 0.418346* 0.469752* 0.351690* 0.501552* 0.300264* 0.483959* 0.487631* 0.539789* 0.365833* 0.480940* 0.416905*
Cytoplasmic Foci 0.130897 0.221340* 0.030202 0.033976 0.213829* 0.328750* 0.009556 0.115359 0.177461 0.269107* 0.013944 0.073018
Eisosomes 0.000072 0.000120 0.000042 0.000102 0.000133 0.000323 0.000024 0.000126 0.000106 0.000211 0.000028 0.000114
Endoplasmic Reticulum 0.000395 0.000570 0.004364 0.004970 0.000726 0.000760 0.001258 0.001381 0.000581 0.000654 0.001918 0.003248
Endosome 0.004621 0.017959 0.010538 0.014858 0.013729 0.035453 0.001406 0.012264 0.009735 0.025739 0.003347 0.013613
Golgi 0.000643 0.005652 0.002023 0.001706 0.002945 0.017849 0.000115 0.000158 0.001935 0.011076 0.000520 0.000963
Lipid Particles 0.004318 0.005690 0.003162 0.004099 0.009014 0.011205 0.000732 0.004958 0.006955 0.008142 0.001248 0.004511
Mitochondria 0.003383 0.016531 0.000501 0.000661 0.004344 0.042446 0.000505 0.000163 0.003923 0.028056 0.000504 0.000422
Mitotic Spindle 0.000663 0.007667 0.019776 0.006254 0.001903 0.009982 0.003550 0.000121 0.001359 0.008697 0.006999 0.003312
None 0.012280 0.003412 0.006063 0.002579 0.004556 0.002142 0.005847 0.004489 0.007943 0.002847 0.005893 0.003495
Nuclear Periphery 0.000312 0.000411 0.001333 0.001750 0.000481 0.000284 0.001153 0.000777 0.000407 0.000355 0.001191 0.001283
Nuclear Periphery Foci 0.000318 0.000228 0.007860 0.004246 0.000342 0.000272 0.000653 0.003093 0.000331 0.000247 0.002185 0.003693
Nucleolus 0.001429 0.001426 0.000695 0.000986 0.001196 0.002186 0.000396 0.001071 0.001298 0.001764 0.000460 0.001027
Nucleus 0.215473* 0.137312* 0.274881* 0.343858* 0.167064* 0.072968 0.442333* 0.261604* 0.188292* 0.108697 0.406741* 0.304399*
Peroxisomes 0.001658 0.016847 0.001320 0.002075 0.004832 0.036720 0.000569 0.000685 0.003440 0.025685 0.000728 0.001408
Vacuole 0.025057 0.078680 0.133148 0.193938 0.050893 0.054331 0.037378 0.102514 0.039563 0.067851 0.057734 0.150079
Vacuole Periphery 0.000666 0.001883 0.001467 0.001902 0.001068 0.003452 0.000136 0.000319 0.000892 0.002581 0.000419 0.001142

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.63 -6.03 -2.17 -0.93 2.05 -4.22 -4.15 -2.23 3.55 -0.82 -6.03 -6.66 -2.38 0.53 -0.14
Bud Neck -18.22 -2.82 2.26 18.79 4.53 -12.69 8.14 11.68 20.02 4.68 -20.49 6.59 10.48 27.53 4.15
Bud Site -10.78 -5.36 -2.16 1.58 1.50 -11.01 -0.52 3.11 12.73 2.59 -15.23 -3.85 -1.56 5.90 0.42
Cell Periphery -2.58 -8.38 -3.05 0.16 4.84 -6.97 2.06 -7.40 -2.79 -7.98 -4.96 -4.05 -7.21 -1.45 -4.50
Cytoplasm 18.81 12.98 12.35 4.64 3.55 23.03 7.64 1.57 -8.56 -2.12 27.23 14.72 9.61 -1.61 1.98
Cytoplasmic Foci -14.18 21.93 18.10 31.78 -0.56 -15.43 42.31 9.43 19.41 -10.95 -18.18 48.06 16.74 29.84 -10.06
Eisosomes -4.01 5.47 -3.29 1.31 -6.13 -2.92 15.19 -0.20 2.86 -9.33 -3.48 16.97 -1.44 3.05 -11.72
Endoplasmic Reticulum -2.98 -10.63 -7.97 -7.69 -1.02 -0.31 -9.21 -3.89 -3.78 1.46 -1.04 -15.00 -8.36 -8.19 -2.58
Endosome -11.85 -3.69 -1.78 3.67 -0.14 -11.21 12.62 0.21 9.42 -7.21 -14.45 10.47 -0.81 8.62 -5.49
Golgi -11.53 -2.16 -0.10 7.27 1.16 -10.93 5.94 5.79 13.86 -1.75 -13.42 5.47 3.87 15.63 -0.23
Lipid Particles -2.04 1.07 1.36 3.51 0.42 -2.29 11.08 3.49 6.10 -6.76 -2.00 11.60 4.11 6.64 -7.26
Mitochondria -8.84 3.67 3.80 12.77 1.06 -14.14 6.75 7.42 16.06 7.97 -16.55 7.27 7.76 20.12 3.46
Mitotic Spindle -5.36 -5.85 -2.07 1.54 4.05 -4.95 -1.73 1.20 5.55 2.65 -7.01 -5.35 -1.17 4.40 3.18
None 6.36 5.44 7.38 2.06 3.16 3.86 -0.84 0.32 -1.87 0.84 7.10 4.16 5.63 -0.53 2.98
Nuclear Periphery -2.08 -15.57 -11.05 -10.21 -2.01 3.80 -17.03 -5.00 -7.44 7.29 1.36 -23.41 -11.24 -11.67 1.10
Nuclear Periphery Foci 2.27 -9.58 -7.70 -7.86 4.05 1.07 -3.86 -5.50 -5.62 -4.45 2.13 -9.68 -9.28 -9.49 -3.35
Nucleolus -0.17 4.51 3.70 4.79 -0.13 -2.62 7.43 0.62 2.78 -4.31 -2.49 8.45 3.33 4.63 -3.54
Nucleus 11.94 -5.29 -2.94 -6.60 0.17 18.95 -34.73 -4.78 -10.17 11.28 19.34 -31.82 -5.50 -11.22 10.43
Peroxisomes -15.87 1.74 1.02 14.34 0.06 -16.65 8.54 8.92 19.32 -1.21 -21.68 8.42 6.35 23.94 -0.94
Vacuole -19.02 -15.10 -12.90 -10.53 -4.76 -1.22 -4.56 -5.54 -5.27 -4.04 -13.47 -13.74 -12.77 -10.81 -8.59
Vacuole Periphery -7.45 -1.19 -0.25 1.92 0.25 -6.30 9.45 7.16 8.50 -5.81 -8.77 6.93 1.09 6.01 -0.95
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytochrome c isoform 2, expressed under hypoxic conditions; also known as iso-2-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; protein abundance increases in response to DNA replication stress; CYC7 has a paralog, CYC1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (28%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Cyc7

Cyc7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cyc7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available