Standard name
Human Ortholog
Description Guanosine diphosphatase located in the Golgi; involved in the transport of GDP-mannose into the Golgi lumen, converting GDP to GMP after mannose is transferred to substrates; null mutants are defective in sporulation and pre-meiotic S phase entry; orthologous to human ENTPD6, a meiosis-associated non-obstructive azoospermia (NOA) related gene identified in GWAS studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.52 0.58 0.53 0.65 0.52 0.51 0.5 0.5 0.6 0.58 0.61 0.64 0.91 0.96 0.99 0.37 0.23 0.28 0 0.08 0 0.07 0.07 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0
Endosome 0.08 0.05 0.13 0.06 0.06 0.05 0.07 0.05 0 0 0 0 0 0 0 0 0.11 0 0.1 0.06 0.09 0.08 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.05 0 0 0.05 0.18 0.19 0.21 0.19 0.29 0.26 0.15 0 0 0 0.08 0 0 0 0 0 0.06 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.22 0.29 0.26 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.54 0.46 0.52 0.56 0.63 0.44 0.44 0.42 0.36 0.41 0.32 0.36 0.08 0 0 0.51 0.56 0.61 0.78 0.77 0.81 0.75 0.81 0.76
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 3 2 1 0 1
Bud 0 6 1 0 0 7 13 14 7 6 10 9 1 0 0 0 0 0 1 4 2 0 2 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 1 2 2 0 1 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 0 0 1 0 0 1 4 0 0 0 0 0 0 0 0 0
Cytoplasm 191 279 346 270 266 369 375 371 393 371 325 387 151 350 461 69 41 52 16 42 17 10 21 20
Endoplasmic Reticulum 8 5 8 0 4 10 6 6 1 0 1 8 2 4 1 8 9 12 1 1 3 1 4 8
Endosome 28 23 88 24 29 39 53 40 21 9 15 16 1 0 1 8 19 7 42 34 67 12 9 11
Golgi 0 0 3 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 4 1 7 0 3 0
Mitochondria 18 26 6 15 28 133 141 155 128 184 140 93 2 0 0 15 3 8 16 17 27 9 11 15
Nucleus 3 6 10 10 15 12 18 28 26 18 10 11 1 3 1 42 52 48 0 4 0 0 0 1
Nuclear Periphery 0 3 0 1 3 2 6 6 2 3 1 1 0 0 0 1 0 1 0 0 1 0 1 1
Nucleolus 0 0 0 1 0 1 7 4 0 0 0 1 0 0 0 0 1 0 1 0 0 0 0 2
Peroxisomes 0 0 0 1 0 0 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 13 2 3 4 2 6 4 4 3 2 0 0 0 1 0 0 1 2 1 0 1 3
Vac/Vac Membrane 199 222 344 233 325 320 328 312 236 264 169 222 13 14 9 96 101 115 332 415 603 111 255 248
Unique Cell Count 367 481 656 413 514 724 754 749 658 644 533 609 166 364 468 187 180 188 424 536 745 149 316 328
Labelled Cell Count 448 573 819 557 673 897 951 947 818 859 676 750 171 373 478 240 226 243 424 536 745 149 316 328


Ambiguous, Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 5.0 5.1 5.3 5.5 4.9 5.0 5.2 5.0 4.5 4.8 5.1 5.4 5.6 5.6 5.7 6.6 7.2 6.2 6.4 6.7
Std Deviation (1e-4) 0.7 0.8 0.8 1.2 1.3 1.2 1.3 1.2 1.0 1.1 1.0 0.9 0.8 1.2 1.2 1.5 1.8 1.9 1.5 1.9 2.7
Intensity Change (Log2) – – – 0.06 0.11 -0.04 -0.01 0.03 -0.01 -0.16 -0.09 0.01 0.09 0.15 0.14 0.17 0.39 0.51 0.28 0.33 0.41


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 3.0 3.1 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4.1 -0.3 -0.7 -1.1 -1.2 2.6 1.8 2.8 3.9 9.0 14.3 16.8 -3.8 -7.1 -6.1
Endoplasmic Reticulum 0 -0.7 0.3 -0.8 -0.8 0 0 0 0.1 0 0 0 0 0 0
Endosome -4.0 -4.4 -5.2 -4.0 -5.2 -6.7 0 0 -7.0 -4.7 -7.3 -8.1 -3.5 -1.0 -3.7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.1 4.6 10.8 10.9 11.6 11.1 0 0 9.5 0 0 0 0 0 0
Nucleus 1.1 1.6 0.2 1.2 2.6 2.7 1.6 0.5 0.4 0 0 0 10.5 12.4 11.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole -2.0 -2.0 -2.4 -3.1 -1.9 -2.2 0 0 -2.7 0 0 -3.1 0 0 0
Vacuole 1.3 3.7 -3.1 -3.4 -4.0 -6.0 -4.1 -7.2 -5.7 -10.4 -15.6 -18.0 -0.3 0.9 2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.5324 3.7055 3.6358 3.6223 6.2641 3.8009 5.0691 6.7711 6.3428 6.2947 7.1527 6.5196 5.4805 7.4091 7.0698 6.5164 6.7567 7.0452
Actin 0.0127 0.0001 0.0078 0.0042 0.0263 0.0014 0.0286 0 0.0029 0.0094 0 0.0003 0.0103 0 0.0053 0.0145 0.0007 0
Bud 0.0008 0.0005 0.0021 0.0001 0.0004 0.0005 0.0005 0.0004 0.0003 0.0004 0.0002 0.0003 0.0002 0.0002 0.0003 0.0004 0.0002 0.0002
Bud Neck 0.002 0.0007 0.0014 0.0003 0.0026 0.0012 0.0009 0.0005 0.0009 0.0014 0.0003 0.0008 0.0027 0.0007 0.0005 0.0009 0.0006 0.0009
Bud Periphery 0.0024 0.0006 0.001 0.0001 0.001 0.0012 0.001 0.0007 0.0003 0.0008 0.0003 0.0007 0.0004 0.0004 0.0006 0.0008 0.0005 0.0006
Bud Site 0.0026 0.0042 0.0034 0.0004 0.0013 0.0005 0.0023 0.0008 0.0029 0.001 0.0003 0.0005 0.0008 0.0007 0.0008 0.0009 0.0004 0.0004
Cell Periphery 0.0013 0.0008 0.0008 0.0001 0.0137 0.0009 0.001 0.0006 0.0004 0.0007 0.0002 0.0007 0.0005 0.0006 0.0004 0.0007 0.0005 0.0006
Cytoplasm 0.0174 0.0289 0.0232 0.0082 0.0058 0.012 0.0104 0.0309 0.0217 0.0097 0.0037 0.0121 0.0083 0.0184 0.0116 0.0024 0.0038 0.0047
Cytoplasmic Foci 0.0199 0.0178 0.0282 0.0134 0.017 0.0104 0.0257 0.0073 0.0175 0.0073 0.0061 0.0123 0.013 0.0039 0.0119 0.0072 0.0051 0.0049
Eisosomes 0.0007 0 0.0001 0.0001 0.0006 0 0.0005 0 0.0001 0.0013 0 0 0.0001 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0138 0.0051 0.0068 0.0031 0.043 0.0056 0.012 0.0066 0.0055 0.0032 0.0011 0.0078 0.0103 0.0099 0.007 0.0023 0.0051 0.0035
Endosome 0.4017 0.3195 0.4137 0.532 0.3214 0.2905 0.4285 0.2804 0.4372 0.4974 0.387 0.359 0.3993 0.2329 0.3877 0.2814 0.4061 0.284
Golgi 0.0168 0.0089 0.0337 0.0138 0.0388 0.0174 0.0337 0.0082 0.0386 0.0223 0.0518 0.0227 0.0189 0.0061 0.0291 0.0095 0.0121 0.0123
Lipid Particles 0.0123 0.0032 0.0096 0.0135 0.0436 0.0051 0.0148 0.0014 0.0055 0.009 0.001 0.0094 0.0084 0.0017 0.0061 0.0024 0.0028 0.0031
Mitochondria 0.0189 0.0055 0.0307 0.002 0.0678 0.0308 0.0252 0.0023 0.028 0.0248 0.0006 0.0177 0.0172 0.0027 0.0152 0.0338 0.0021 0.0084
None 0.0146 0.0093 0.0264 0.0416 0.0038 0.0051 0.0023 0.0175 0.0116 0.0012 0 0.0026 0.0009 0.0003 0.0066 0.0001 0.0003 0.0001
Nuclear Periphery 0.0196 0.0132 0.0096 0.0044 0.0213 0.0144 0.0145 0.0077 0.0041 0.0065 0.002 0.0101 0.0101 0.0124 0.0081 0.003 0.0198 0.0054
Nucleolus 0.002 0.0009 0.0012 0.0006 0.0011 0.0013 0.0012 0.001 0.0006 0.0009 0.0002 0.0006 0.0005 0.0005 0.0005 0.0005 0.0007 0.0004
Nucleus 0.0121 0.0043 0.0036 0.0011 0.0032 0.0033 0.0044 0.0038 0.002 0.0016 0.0008 0.002 0.0022 0.0023 0.0017 0.0011 0.0026 0.0014
Peroxisomes 0.0066 0.0006 0.0067 0.0011 0.0239 0.0075 0.0017 0.0001 0.0023 0.0019 0.0001 0.0008 0.0029 0.0001 0.0008 0.0094 0.0002 0.0002
Punctate Nuclear 0.0046 0.0002 0.0044 0.0022 0.0118 0.0013 0.008 0.0002 0.0024 0.0005 0 0.0002 0.0007 0.0001 0.0001 0.0001 0.0008 0
Vacuole 0.3017 0.4691 0.2947 0.2576 0.2628 0.4468 0.2807 0.4754 0.3015 0.2879 0.4234 0.3798 0.3472 0.528 0.3418 0.4602 0.377 0.4957
Vacuole Periphery 0.1155 0.1065 0.091 0.1001 0.0888 0.1428 0.1021 0.1542 0.1136 0.1108 0.1208 0.1594 0.1449 0.178 0.1635 0.1684 0.1588 0.173

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 137.1283 127.3357 104.8306 78.6937 113.0156 106.2422 130.1902 106.1352 90.3804 120.7159
Translational Efficiency 1.2045 1.2834 0.9178 1.1423 0.9222 1.2575 0.9835 0.9284 0.9073 0.8395

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
117 1200 1334 620 2016 1352 375 71 2133 2552 1709 691

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 812.38 827.15 831.53 863.61 749.25 805.89 911.00 947.20 752.71 815.89 848.97 872.20
Standard Deviation 153.38 114.43 104.65 129.82 97.14 104.61 99.36 130.48 102.05 109.85 108.61 132.34
Intensity Change Log 2 — 0.025994 0.033614 0.088225 — 0.105136 0.282004 0.338222 — 0.064507 0.158131 0.213583

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.005962 0.000494 0.000424 0.001242 0.000115 0.000435 0.001635 0.000514 0.000435 0.000462 0.000689 0.001167
Bud Neck 0.008863 0.011199 0.010449 0.014332 0.009938 0.014142 0.014666 0.009542 0.009879 0.012758 0.011374 0.013840
Bud Site 0.048096 0.015150 0.009043 0.040218 0.010158 0.010677 0.016231 0.013116 0.012239 0.012780 0.010620 0.037433
Cell Periphery 0.000392 0.000103 0.000301 0.000122 0.000259 0.000248 0.000083 0.000059 0.000267 0.000180 0.000253 0.000116
Cytoplasm 0.124439* 0.105983* 0.352158* 0.140426* 0.039792 0.060001 0.113659* 0.235971* 0.044435 0.081623 0.299825* 0.150244*
Cytoplasmic Foci 0.116818 0.255541* 0.115539 0.137290 0.112416 0.158704 0.171001 0.177949 0.112657 0.204239* 0.127709 0.141468
Eisosomes 0.000121 0.000088 0.000123 0.000047 0.000063 0.000147 0.000085 0.000064 0.000066 0.000119 0.000115 0.000049
Endoplasmic Reticulum 0.002529 0.003000 0.004094 0.005719 0.004796 0.004632 0.004474 0.001129 0.004671 0.003865 0.004177 0.005248
Endosome 0.156167 0.210854* 0.049800 0.156266 0.247015* 0.251444* 0.141161 0.120970 0.242032* 0.232358* 0.069847 0.152640
Golgi 0.014901 0.043911 0.001580 0.015677 0.038451 0.037984 0.003131 0.000754 0.037159 0.040771 0.001920 0.014144
Lipid Particles 0.017785 0.009800 0.014845 0.006606 0.006230 0.013487 0.018949 0.006073 0.006864 0.011753 0.015745 0.006551
Mitochondria 0.047696 0.012304 0.001261 0.005828 0.019938 0.025465 0.001858 0.000220 0.021461 0.019276 0.001392 0.005252
Mitotic Spindle 0.012305 0.004434 0.012825 0.057226 0.000725 0.001426 0.034481 0.016211 0.001360 0.002841 0.017577 0.053011
None 0.000122 0.000193 0.005572 0.000355 0.000149 0.000208 0.000673 0.000618 0.000147 0.000201 0.004497 0.000382
Nuclear Periphery 0.000695 0.000223 0.002444 0.002075 0.000175 0.000356 0.002802 0.001190 0.000204 0.000293 0.002523 0.001984
Nuclear Periphery Foci 0.001485 0.000414 0.004774 0.005795 0.000179 0.000342 0.012454 0.003415 0.000250 0.000376 0.006459 0.005551
Nucleolus 0.000689 0.000489 0.004264 0.000796 0.000402 0.000688 0.004580 0.000804 0.000417 0.000594 0.004333 0.000797
Nucleus 0.011232 0.005812 0.203180* 0.014014 0.002861 0.006393 0.068299 0.042044 0.003321 0.006120 0.173583* 0.016894
Peroxisomes 0.017273 0.008771 0.004640 0.017680 0.003267 0.009550 0.027700 0.035126 0.004035 0.009184 0.009700 0.019473
Vacuole 0.401459* 0.289651* 0.200339* 0.365170* 0.447045* 0.365993* 0.359196* 0.333366* 0.444545* 0.330096* 0.235196* 0.361902*
Vacuole Periphery 0.010973 0.021587 0.002349 0.013116 0.056028 0.037679 0.002883 0.000866 0.053556 0.030112 0.002466 0.011857

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.27 1.29 1.09 -2.77 -3.14 -2.31 -4.48 -2.02 0.23 3.38 -0.34 -1.42 -2.43 -2.86 -1.73
Bud Neck -1.50 -1.16 -2.38 -1.59 -1.87 -3.11 -2.61 1.11 3.06 2.84 -2.99 -1.51 -2.37 -0.20 -1.10
Bud Site 2.44 2.98 0.90 -4.84 -6.61 -0.47 -2.17 -0.09 0.07 1.12 -0.68 1.37 -5.73 -5.55 -6.24
Cell Periphery 2.07 0.59 2.10 0.11 4.75 0.33 8.17 9.90 6.45 4.00 3.23 1.04 7.71 4.17 4.77
Cytoplasm 2.01 -9.82 -0.93 -5.92 15.55 -5.13 -9.90 -6.35 -5.70 -3.01 -9.82 -35.99 -14.28 -10.08 11.83
Cytoplasmic Foci -10.77 -0.21 0.21 17.71 0.77 -7.95 -3.29 -1.26 1.01 0.18 -18.06 -1.49 0.20 13.71 1.29
Eisosomes 0.84 -0.04 2.17 5.68 6.99 -4.33 -4.05 0.02 4.09 2.85 -4.70 -5.18 3.15 6.42 7.76
Endoplasmic Reticulum -0.88 -2.39 -1.21 -0.77 0.14 0.27 -0.77 8.36 5.80 6.40 1.69 0.58 0.82 0.13 0.62
Endosome -3.52 4.52 1.58 12.19 -7.87 -0.51 15.28 8.39 8.50 1.33 1.50 32.65 17.37 17.23 -5.98
Golgi -6.14 2.71 0.81 10.15 -4.09 0.16 16.20 17.16 14.53 4.29 -1.24 16.81 10.82 12.82 -3.92
Lipid Particles 0.98 0.30 1.70 4.21 5.52 -5.59 -4.12 0.84 4.84 4.12 -5.39 -5.75 1.52 6.72 6.69
Mitochondria 1.87 2.61 2.44 5.21 -2.23 -2.36 12.83 15.53 13.00 1.90 0.98 13.49 10.16 10.37 -2.04
Mitotic Spindle 1.04 -0.62 -4.29 -6.99 -5.06 -1.53 -5.84 -1.53 -1.48 0.70 -2.49 -8.13 -7.68 -7.39 -4.33
None -1.11 -5.09 -2.94 -2.56 4.71 -1.35 -4.04 -1.77 -1.47 1.94 -1.59 -5.36 -3.28 -2.75 4.87
Nuclear Periphery 2.01 -6.67 -2.06 -2.90 0.73 -3.55 -8.07 -3.13 -2.62 4.10 -2.44 -15.82 -3.12 -2.97 1.31
Nuclear Periphery Foci 2.59 -7.19 -3.55 -4.81 0.61 -2.22 -7.16 -2.05 -1.95 3.90 -2.35 -12.90 -5.29 -5.14 2.41
Nucleolus 0.63 -6.54 -1.31 -3.72 6.36 -1.92 -3.67 -1.82 -0.13 3.40 -2.08 -8.42 -4.60 -2.63 7.01
Nucleus 2.22 -24.72 -3.03 -8.15 24.30 -3.49 -10.37 -4.57 -4.23 2.48 -3.79 -30.09 -10.26 -8.98 23.73
Peroxisomes 1.57 2.55 0.66 -2.23 -4.86 -6.95 -5.70 -2.65 -1.77 -0.15 -8.12 -4.94 -5.87 -2.57 -2.97
Vacuole 4.18 6.65 -0.71 -10.60 -16.66 7.21 3.67 1.05 -1.16 -0.58 12.43 20.64 0.07 -8.57 -14.40
Vacuole Periphery -3.57 2.29 0.46 6.32 -3.06 8.48 32.57* 34.20* 25.29 3.94 12.81 32.76 20.71 12.19 -2.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Guanosine diphosphatase located in the Golgi; involved in the transport of GDP-mannose into the Golgi lumen, converting GDP to GMP after mannose is transferred to substrates; null mutants are defective in sporulation and pre-meiotic S phase entry; orthologous to human ENTPD6, a meiosis-associated non-obstructive azoospermia (NOA) related gene identified in GWAS studies
Localization
Cell Percentages vacuole (70%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Gda1

Gda1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gda1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available