Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 0 0.08 0.1 0.11 0.08 0.08 0.06 0.06 0.05 0.05 0.05 0.21 0.24 0.29 0.12 0.12 0.14 0.05 0 0 0.09 0.07 0.05
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.15 0 0 0 0 0 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.55 0.09 0.14 0.26 0.29 0.64 0.64 0.56 0.62 0.78 0.72 0.75 0 0 0 0 0.05 0.09 0 0 0 0 0.05 0.07
Nucleus 0.58 0.79 0.67 0.69 0.57 0.52 0.52 0.56 0.5 0.5 0.45 0.47 0.71 0.62 0.64 0.69 0.6 0.43 0.59 0.69 0.54 0.47 0.4 0.24
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0.06
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.05 0.06 0.09
Vac/Vac Membrane 0.05 0.21 0.1 0.07 0.13 0.1 0.09 0.06 0.05 0.08 0.08 0.09 0.08 0.14 0.09 0.17 0.29 0.31 0.22 0.11 0.19 0.24 0.29 0.36
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 1
Bud 0 0 1 3 3 7 7 21 16 12 13 12 0 0 0 1 0 1 2 3 8 3 5 3
Bud Neck 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 3 2 4 3
Bud Site 0 0 0 1 1 12 10 18 12 8 16 14 0 0 0 1 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 23 5 33 31 36 44 44 44 35 29 27 26 52 78 104 21 27 32 12 3 14 21 24 18
Endoplasmic Reticulum 0 2 1 0 1 1 1 0 0 0 0 0 1 0 1 8 9 14 0 0 0 1 1 1
Endosome 0 0 28 10 10 4 4 12 2 1 3 1 5 14 9 3 7 34 6 4 20 5 8 21
Golgi 0 0 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0
Mitochondria 131 12 57 82 98 374 374 394 337 494 364 392 3 0 0 7 11 21 5 2 18 4 17 26
Nucleus 137 111 281 219 192 302 302 394 271 318 228 245 176 200 225 117 131 99 161 117 318 111 133 85
Nuclear Periphery 2 0 1 0 0 3 1 3 1 3 4 6 0 0 0 0 2 0 1 0 7 2 0 5
Nucleolus 0 0 1 3 1 4 4 9 12 21 14 12 0 0 0 1 0 1 4 5 27 8 15 21
Peroxisomes 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 1 0 11 7 2 5 5 16 5 1 3 1 2 1 3 0 5 7 8 8 28 11 19 32
Vac/Vac Membrane 12 29 44 22 45 56 50 40 28 50 41 46 19 44 31 28 64 72 61 18 113 57 96 130
Unique Cell Count 238 140 421 317 337 584 581 698 540 636 504 523 247 321 353 169 220 229 274 170 587 235 334 364
Labelled Cell Count 307 159 461 382 389 812 802 952 719 937 713 755 258 337 374 187 257 282 274 170 587 235 334 364


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 5.0 4.5 4.3 4.3 3.8 3.8 3.8 3.7 3.5 3.4 3.5 5.9 5.9 5.6 6.4 6.2 6.1 6.0 6.1 6.4
Std Deviation (1e-4) 0.5 0.6 0.9 1.4 1.1 1.0 1.0 1.0 0.7 0.6 0.8 1.0 1.2 1.1 0.9 1.3 1.6 1.4 1.6 1.4 1.6
Intensity Change (Log2) – – – -0.06 -0.08 -0.27 -0.27 -0.26 -0.3 -0.38 -0.41 -0.39 0.39 0.37 0.32 0.5 0.45 0.43 0.41 0.42 0.5

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.9 1.4 -0.2 -0.2 -1.0 -0.8 -2.2 -1.5 -1.8 4.9 6.2 7.9 1.7 1.8 2.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.8
Endosome 0 0 0 0 0 0 0 0 0 -2.7 -1.3 -2.7 -2.4 -1.8 3.4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -5.4 -6.9 -7.2 -3.3 -3.3 -1.6
Nucleus 0.7 -2.8 -4.8 -4.7 -3.4 -5.2 -5.4 -6.5 -6.1 1.2 -1.3 -0.9 0.6 -1.8 -5.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 -2.5 -1.8 0 -0.3 0.3
Vacuole -1.7 1.2 -0.5 -1.0 -2.9 -3.1 -1.4 -1.2 -0.9 -1.2 1.4 -0.8 2.1 6.0 6.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.1986 -0.1476 -0.2345 -0.4706 -0.051 -0.3953 0.6563 0.6376 0.4367 0.5343 0.8645 0.5413 -0.5176 -0.3962 -0.524 -0.2354 -0.6237 -0.2178
Actin 0.0226 0.0004 0.0133 0.0373 0.014 0.0008 0.0157 0.0001 0.0023 0.0153 0.0068 0.0038 0.0003 0.0005 0.0002 0.0001 0.0005 0.0019
Bud 0.0007 0.0017 0.0009 0.021 0.0023 0.0001 0.0006 0.0001 0.0002 0.0008 0.0007 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0001
Bud Neck 0.0034 0.0008 0.0076 0.0031 0.0023 0.0059 0.0142 0.0006 0.002 0.0004 0.0134 0.0061 0.0006 0.0006 0.0009 0.0004 0.0012 0.0028
Bud Periphery 0.0014 0.0003 0.0005 0.0083 0.0009 0.0002 0.0014 0.0001 0.0004 0.0021 0.0012 0.0005 0 0.0001 0 0 0.0001 0.0001
Bud Site 0.0016 0.0076 0.0066 0.0095 0.0047 0.0004 0.0038 0.0006 0.0014 0.0005 0.0037 0.0002 0.0005 0.0008 0.0007 0.0001 0.0002 0.0001
Cell Periphery 0.0003 0.0001 0.0001 0.0007 0.0001 0.0001 0.0003 0 0.0001 0.0001 0.0002 0 0 0.0001 0 0 0 0
Cytoplasm 0.0666 0.1064 0.0469 0.0217 0.0595 0.0264 0.0302 0.0564 0.0362 0.0192 0.0482 0.0133 0.0317 0.0514 0.0274 0.0341 0.0238 0.0145
Cytoplasmic Foci 0.0271 0.0051 0.0035 0.0193 0.0197 0.0101 0.0063 0.0007 0.0071 0.0009 0.0154 0.0012 0.0033 0.0025 0.0019 0.0003 0.0104 0.0025
Eisosomes 0.0004 0 0.0002 0.0004 0.0002 0 0.0002 0 0.0001 0.0001 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0073 0.0045 0.0026 0.0018 0.0036 0.002 0.0048 0.0015 0.0022 0.0018 0.0026 0.001 0.0021 0.0038 0.0023 0.0007 0.0013 0.0009
Endosome 0.0192 0.0045 0.0052 0.0294 0.0261 0.0082 0.0185 0.0022 0.0088 0.0062 0.0296 0.0035 0.0024 0.0058 0.0021 0.0009 0.0129 0.0041
Golgi 0.0036 0.0001 0.0012 0.0332 0.0066 0.0037 0.0075 0 0.0011 0.0026 0.0037 0.0007 0.0001 0.0001 0 0 0.0009 0.001
Lipid Particles 0.0087 0.0009 0.0022 0.0216 0.0184 0.0032 0.0126 0.0001 0.0046 0.0007 0.0143 0.0033 0.0002 0.0006 0.0003 0 0.0027 0.0005
Mitochondria 0.011 0.0007 0.0015 0.0199 0.0019 0.0021 0.0126 0.0005 0.0056 0.0071 0.0024 0.0023 0.0004 0.0008 0.0003 0.0004 0.0004 0.0004
None 0.1756 0.1601 0.1293 0.0518 0.1665 0.0458 0.0249 0.0677 0.0433 0.0135 0.0417 0.0237 0.0567 0.0584 0.054 0.0499 0.0374 0.0285
Nuclear Periphery 0.0535 0.0423 0.0376 0.0103 0.0264 0.0194 0.0365 0.0167 0.0268 0.0257 0.0283 0.0181 0.0218 0.049 0.0193 0.023 0.0272 0.012
Nucleolus 0.0085 0.012 0.0089 0.0092 0.0185 0.0249 0.0119 0.0087 0.0087 0.0068 0.0246 0.0204 0.0061 0.0101 0.0062 0.0051 0.01 0.0156
Nucleus 0.5001 0.5907 0.6664 0.584 0.425 0.7867 0.7465 0.807 0.7639 0.8068 0.6536 0.82 0.8243 0.7596 0.8395 0.8568 0.7022 0.8693
Peroxisomes 0.0136 0.0003 0.0008 0.034 0.0035 0.0014 0.0073 0 0.0038 0.0003 0.004 0.0042 0.0001 0.0001 0.0002 0 0.0019 0.0002
Punctate Nuclear 0.0676 0.0568 0.0629 0.0782 0.1976 0.0565 0.0403 0.0336 0.0794 0.0872 0.0973 0.0759 0.0479 0.0495 0.042 0.0274 0.1658 0.0442
Vacuole 0.005 0.0036 0.0013 0.0035 0.0014 0.0014 0.0026 0.0027 0.0015 0.0008 0.0064 0.001 0.0011 0.0046 0.0024 0.0005 0.0007 0.0008
Vacuole Periphery 0.0023 0.0009 0.0006 0.0019 0.0008 0.0006 0.0014 0.0005 0.0007 0.0011 0.0017 0.0005 0.0003 0.0014 0.0003 0.0002 0.0004 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.6701 26.7039 23.5309 28.1794 19.3653 24.2577 20.6721 27.9046 26.6052 28.8846
Translational Efficiency 1.6923 1.4252 1.3217 1.3628 1.6853 1.0467 1.4199 1.29 1.2261 1.0442

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1254 254 1040 1436 1581 1784 1682 989 2835 2038 2722 2425

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 689.59 783.27 883.32 819.61 658.16 717.35 886.45 847.68 672.06 725.57 885.25 831.06
Standard Deviation 73.63 94.65 97.41 100.31 92.75 85.65 109.76 111.01 86.25 89.51 105.22 105.71
Intensity Change Log 2 — 0.183771 0.357197 0.249199 — 0.124239 0.429601 0.365081 — 0.155006 0.393009 0.306952

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000082 0.001043 0.000509 0.000700 0.000163 0.000201 0.000344 0.001771 0.000127 0.000306 0.000407 0.001137
Bud Neck 0.002920 0.013797 0.010631 0.015113 0.002569 0.005570 0.005747 0.013129 0.002724 0.006595 0.007613 0.014304
Bud Site 0.000568 0.005664 0.006067 0.008872 0.001165 0.002441 0.002369 0.028386 0.000901 0.002843 0.003782 0.016830
Cell Periphery 0.000111 0.000272 0.000093 0.000149 0.000117 0.000239 0.000083 0.000197 0.000114 0.000243 0.000087 0.000169
Cytoplasm 0.116832 0.152593 0.011803 0.055591 0.161397 0.133819 0.026511 0.139842 0.141685 0.136159 0.020891 0.089952
Cytoplasmic Foci 0.028229 0.048138 0.000437 0.001123 0.020097 0.024302 0.000352 0.004704 0.023694 0.027273 0.000385 0.002584
Eisosomes 0.000037 0.000086 0.000028 0.000028 0.000031 0.000042 0.000020 0.000037 0.000034 0.000047 0.000023 0.000032
Endoplasmic Reticulum 0.001727 0.006676 0.007234 0.013149 0.001746 0.001817 0.005533 0.006965 0.001737 0.002423 0.006183 0.010627
Endosome 0.001126 0.006207 0.000674 0.001497 0.001122 0.002732 0.000444 0.005782 0.001123 0.003165 0.000532 0.003245
Golgi 0.000652 0.002341 0.000076 0.000567 0.000670 0.000523 0.000036 0.003481 0.000662 0.000750 0.000051 0.001755
Lipid Particles 0.005077 0.007106 0.000401 0.000652 0.003196 0.004133 0.000386 0.001332 0.004028 0.004503 0.000392 0.000930
Mitochondria 0.003884 0.009232 0.002312 0.002225 0.002643 0.005721 0.000823 0.007696 0.003192 0.006158 0.001392 0.004456
Mitotic Spindle 0.001674 0.004743 0.004704 0.016764 0.002083 0.001322 0.001951 0.029184 0.001902 0.001748 0.003003 0.021829
None 0.006514 0.005849 0.002964 0.004210 0.016507 0.011365 0.004794 0.009493 0.012087 0.010678 0.004094 0.006364
Nuclear Periphery 0.002503 0.002086 0.001382 0.004144 0.002342 0.002642 0.001458 0.002018 0.002413 0.002573 0.001429 0.003277
Nuclear Periphery Foci 0.000739 0.002178 0.000471 0.001201 0.000917 0.000507 0.000360 0.002041 0.000839 0.000716 0.000402 0.001544
Nucleolus 0.006061 0.006690 0.003656 0.001159 0.006709 0.005405 0.001756 0.001237 0.006422 0.005565 0.002482 0.001191
Nucleus 0.814774 0.695288 0.939043 0.852772 0.770481 0.785047 0.940585 0.695705 0.790073 0.773860 0.939996 0.788715
Peroxisomes 0.002242 0.008168 0.000251 0.000206 0.001291 0.001869 0.000102 0.001460 0.001712 0.002654 0.000159 0.000718
Vacuole 0.003916 0.021119 0.006975 0.019110 0.004483 0.009435 0.006224 0.039205 0.004232 0.010891 0.006511 0.027305
Vacuole Periphery 0.000331 0.000722 0.000291 0.000768 0.000271 0.000868 0.000124 0.006335 0.000298 0.000850 0.000187 0.003038

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.16 -11.38 -5.00 1.19 -0.87 -0.48 -4.85 -3.68 -3.31 -2.57 -2.14 -10.17 -5.85 -3.51 -2.87
Bud Neck -3.33 -6.10 -8.72 -0.90 -2.28 -3.98 -4.68 -7.30 -4.68 -3.41 -5.08 -7.58 -11.33 -6.75 -4.69
Bud Site -4.34 -3.99 -5.42 -0.33 -0.51 -2.00 -2.28 -5.81 -5.20 -5.23 -3.69 -4.67 -7.71 -5.61 -4.89
Cell Periphery -2.49 0.56 -1.46 2.16 -2.32 -3.63 3.52 -3.25 2.33 -6.16 -4.23 2.79 -2.99 3.27 -5.97
Cytoplasm -2.34 19.69 11.79 7.41 -12.65 3.69 23.60 6.65 3.54 -14.58 0.89 30.24 14.30 12.13 -17.81
Cytoplasmic Foci -2.59 12.66 12.53 7.16 -1.34 -1.55 13.98 11.72 12.67 -6.68 -1.19 18.61 17.46 15.38 -6.34
Eisosomes -4.82 1.07 1.03 5.09 -0.30 -2.67 2.77 -6.98 -4.26 -10.03 -4.32 2.97 -4.16 1.49 -7.54
Endoplasmic Reticulum -6.71 -15.73 -17.20 -6.45 -6.43 -0.27 -16.81 -18.31 -18.06 -5.63 -3.74 -23.13 -22.97 -20.42 -9.02
Endosome -2.48 1.88 -0.34 2.44 -1.93 -3.45 4.25 -3.66 -0.69 -4.92 -4.30 4.46 -3.23 2.19 -5.43
Golgi -1.37 2.01 1.11 1.72 -1.48 0.44 2.29 -1.03 -1.33 -2.33 -0.20 3.05 -0.14 0.06 -2.75
Lipid Particles -1.78 9.36 8.93 6.81 -2.52 -1.26 9.61 6.65 6.96 -4.99 -0.40 13.25 11.49 9.71 -5.59
Mitochondria -1.56 1.34 1.71 2.16 0.26 -2.50 2.79 -0.82 1.26 -2.43 -2.56 2.92 0.49 2.94 -2.57
Mitotic Spindle -1.27 -2.08 -4.87 -1.58 -2.64 0.99 -0.21 -6.03 -6.38 -5.99 0.05 -1.66 -7.67 -7.72 -6.66
None 0.81 4.55 3.22 1.89 -2.14 2.44 7.07 5.11 3.30 -3.03 0.95 8.11 6.50 5.29 -2.98
Nuclear Periphery 1.52 3.44 -8.84 -9.76 -13.02 -0.73 1.35 -4.02 -3.10 -6.45 -0.48 2.80 -8.61 -6.04 -14.01
Nuclear Periphery Foci -2.39 -0.54 -1.64 1.27 -0.58 3.10 2.37 -2.22 -4.47 -4.01 1.82 0.92 -2.41 -3.70 -2.85
Nucleolus 0.54 2.95 6.63 5.48 4.72 2.82 5.73 7.54 8.04 2.40 2.82 6.51 9.86 8.87 4.47
Nucleus 5.98 -14.13 -3.93 -7.88 11.68 -1.77 -21.52 4.88 6.47 21.99 1.83 -25.60 -0.51 -2.25 23.88
Peroxisomes -3.90 4.10 4.36 5.58 2.05 -1.11 5.20 2.55 3.78 -2.30 -2.13 6.31 5.43 7.67 -1.77
Vacuole -5.48 -5.00 -13.42 -2.06 -9.63 -4.42 -5.84 -15.34 -14.27 -13.71 -6.88 -7.70 -19.75 -16.08 -16.39
Vacuole Periphery -2.51 0.41 -0.55 1.33 -0.84 -2.36 2.84 -2.19 -1.53 -2.35 -2.48 1.99 -2.29 -0.84 -2.57
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor
Localization
Cell Percentages nucleus (84%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Rml2

Rml2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rml2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available