Standard name
Human Ortholog
Description Non-catalytic subunit of the NatC N-terminal acetyltransferase; required for replication of dsRNA virus; expression is glucose-repressible; human NatC ortholog, Naa35, requires co-expression of the human catalytic subunit, Naa30, to functionally complement the null allele
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 – 0 0 0 0 0 0.08 0.09 0.06 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.99 1.0 0.99 0.96 0.96 0.96 0.85 – 0.73 0.82 0.98 0.98 0.99 0.97 0.96 0.9 0.95 0.96 0.91 0.79 0.83 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.09 0.07 0 0.36 – 0.49 0.3 0 0 0 0 0 0 0 0 0 0.05 0.05 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.07 0 0 0 0.07 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 1 0 – 0 0 0 0 0 1 1 0 0 0 0 0 1 3
Bud 0 1 3 2 2 2 3 2 6 – 7 4 7 4 3 1 0 0 1 0 0 0 8 4
Bud Neck 0 0 3 0 2 2 10 9 1 – 2 1 0 1 0 0 0 0 0 0 2 1 3 2
Bud Site 0 0 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 17 2 5 7 4 5 7 – 3 1 3 7 3 29 22 11 0 0 0 0 0 2
Cytoplasm 176 83 324 284 380 428 588 598 347 – 212 65 441 530 644 359 239 179 171 100 305 126 385 475
Endoplasmic Reticulum 1 1 0 0 0 0 3 0 0 – 1 0 2 3 0 17 13 4 0 0 1 5 10 10
Endosome 0 0 0 0 0 0 0 1 0 – 1 0 1 0 0 1 0 1 1 0 1 1 2 3
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 3 0 1 0 0 0 1 1 2
Mitochondria 4 2 0 3 5 39 41 28 146 – 142 24 3 10 8 0 2 4 1 0 7 8 23 20
Nucleus 0 0 4 3 2 0 4 4 2 – 1 0 0 1 0 0 4 2 0 0 2 0 0 0
Nuclear Periphery 1 0 0 0 0 0 0 0 0 – 0 0 0 1 1 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 1 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 0 4 0 – 0 1 0 0 0 0 0 0 0 0 0 0 1 2
Vac/Vac Membrane 0 0 0 0 2 1 2 5 3 – 5 1 0 2 1 7 2 13 1 1 7 10 17 15
Unique Cell Count 179 85 326 285 385 444 612 626 407 292 79 448 539 649 370 249 198 181 105 336 160 465 549
Labelled Cell Count 183 87 351 294 399 480 655 657 513 374 97 458 559 661 418 283 215 181 105 336 160 465 549


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 5.1 5.7 5.2 5.8 4.6 4.6 4.9 3.9 – 3.7 3.7 5.8 5.3 5.6 9.1 9.0 8.8 5.0 5.0 5.6
Std Deviation (1e-4) 0.7 0.7 0.8 1.2 1.2 1.0 1.0 1.1 0.8 – 0.9 0.5 1.0 1.1 1.0 1.6 1.2 1.2 1.2 0.9 1.1
Intensity Change (Log2) – – – -0.13 0.01 -0.33 -0.31 -0.23 -0.57 – -0.62 -0.62 0.02 -0.11 -0.03 0.67 0.66 0.62 -0.19 -0.2 -0.03

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery -3.2 -3.0 0 0 -4.3 0 – 0 0 -3.9 -3.4 -4.9 1.4 1.7 0.2
Cytoplasm 0.5 -0.9 -2.7 -2.9 -3.2 -6.8 – -9.8 -7.0 -1.2 -1.3 -0.3 -2.3 -2.8 -5.1
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 3.9 4.2 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 3.9 0 – 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.5066 1.0492 0.7172 0.7634 0.3504 0.8489 -0.2767 0.4869 0.5508 0.3493 -0.193 0.294 0.9196 1.6255 1.2765 1.6424 1.1288 1.1714
Actin 0.0177 0.0063 0.0101 0.0044 0.0692 0.0034 0.0425 0.0001 0.0229 0.0035 0.0111 0.0013 0.0266 0.0021 0.024 0.0041 0.0328 0.0001
Bud 0.0008 0.0007 0.0009 0.0069 0.001 0.0004 0.0015 0.0001 0.0011 0.0002 0.0088 0.0002 0.0006 0.0009 0.0008 0.0001 0.0013 0
Bud Neck 0.0057 0.0011 0.0006 0.0009 0.0007 0.0012 0.0122 0.0001 0.0011 0.0004 0.0004 0.0005 0.0051 0.0002 0.0004 0.0003 0.0005 0.0006
Bud Periphery 0.0014 0.0008 0.0007 0.0114 0.0009 0.0005 0.002 0 0.0013 0.0003 0.0252 0.0002 0.0007 0.0006 0.0007 0.0001 0.0016 0
Bud Site 0.0022 0.0086 0.0172 0.0011 0.0058 0.0007 0.018 0.0007 0.0043 0.0003 0.0076 0.0002 0.013 0.0044 0.0015 0.0003 0.0015 0
Cell Periphery 0.0006 0.0013 0.0006 0.0004 0.0002 0.0002 0.0007 0.0001 0.0003 0.0002 0.0005 0 0.0005 0.0001 0.0002 0.0001 0.0001 0
Cytoplasm 0.4955 0.6324 0.6279 0.7237 0.4432 0.6418 0.5172 0.8378 0.7346 0.8167 0.7087 0.8563 0.5923 0.799 0.854 0.802 0.7428 0.8814
Cytoplasmic Foci 0.0235 0.0349 0.0186 0.014 0.0149 0.0168 0.0502 0.0073 0.0394 0.0244 0.0167 0.0207 0.0398 0.0115 0.0096 0.0229 0.0283 0.0102
Eisosomes 0.0004 0.0003 0.0003 0.0001 0.0003 0.0001 0.0004 0 0.0002 0.0001 0.0001 0 0.0003 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.0097 0.0033 0.006 0.0128 0.0046 0.0037 0.0077 0.0014 0.0039 0.0037 0.0061 0.0019 0.0077 0.0021 0.0037 0.0032 0.0013 0.0022
Endosome 0.0219 0.0115 0.0135 0.0195 0.0168 0.0108 0.0585 0.0072 0.0278 0.0345 0.0516 0.0175 0.0357 0.0045 0.0071 0.0259 0.0287 0.009
Golgi 0.0035 0.0017 0.0017 0.0016 0.0064 0.0038 0.0255 0.0003 0.0113 0.0116 0.004 0.0086 0.0151 0.0008 0.0015 0.0104 0.034 0.0003
Lipid Particles 0.0059 0.0014 0.0028 0.0007 0.0023 0.0043 0.0227 0.0001 0.0093 0.0027 0.0023 0.001 0.0219 0.0002 0.001 0.0066 0.027 0
Mitochondria 0.0022 0.0005 0.0009 0.0012 0.0022 0.0015 0.0118 0.0001 0.0105 0.0206 0.0084 0.0061 0.006 0.0002 0.0013 0.0007 0.0272 0.0001
None 0.3703 0.2834 0.2832 0.1846 0.4192 0.3047 0.1818 0.1406 0.1018 0.0706 0.1222 0.0777 0.1872 0.1702 0.0853 0.1073 0.0126 0.094
Nuclear Periphery 0.0127 0.0005 0.0024 0.0024 0.0033 0.0006 0.0088 0.0004 0.0053 0.0009 0.0067 0.0006 0.0053 0.0004 0.0007 0.0009 0.0003 0.0003
Nucleolus 0.0007 0.0004 0.0004 0.0002 0.0002 0.0001 0.0015 0 0.0006 0.0001 0.0006 0 0.0055 0 0.0001 0 0.0001 0
Nucleus 0.0103 0.0019 0.0017 0.0018 0.0016 0.0008 0.0033 0.0006 0.0022 0.0008 0.0023 0.0006 0.0044 0.0005 0.0009 0.0009 0.0004 0.0004
Peroxisomes 0.0033 0.0007 0.0006 0.0002 0.0014 0.0017 0.016 0 0.0117 0.0005 0.0007 0.0043 0.0212 0.0003 0.0021 0.0035 0.0559 0
Punctate Nuclear 0.0043 0.0009 0.0035 0.0007 0.0015 0.001 0.0082 0.0002 0.0019 0.0004 0.001 0.0002 0.0058 0.0004 0.0003 0.0004 0.0003 0.0001
Vacuole 0.0056 0.0071 0.0058 0.0098 0.0035 0.0015 0.0069 0.0026 0.0074 0.0061 0.0109 0.0014 0.0041 0.0013 0.0044 0.0093 0.0022 0.001
Vacuole Periphery 0.0019 0.0004 0.0006 0.0016 0.0008 0.0003 0.0028 0.0003 0.0012 0.0014 0.004 0.0005 0.0011 0.0001 0.0004 0.0011 0.0008 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.0437 19.2617 16.9521 20.7761 12.0192 16.0261 20.4945 23.6909 16.9939 24.0831
Translational Efficiency 0.7845 0.6918 0.7102 0.4577 0.828 0.7593 0.6718 0.3978 0.524 0.4399

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1365 1267 1673 1305 1735 1046 1606 2222 3100 2313 3279 3527

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 655.75 730.38 831.12 804.24 667.20 763.27 781.08 965.55 662.16 745.25 806.61 905.86
Standard Deviation 80.70 104.67 107.67 121.31 81.44 100.59 105.35 139.93 81.31 104.14 109.44 154.42
Intensity Change Log 2 — 0.155501 0.341911 0.294480 — 0.194074 0.227351 0.533232 — 0.175084 0.285272 0.419820

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000075 0.000169 0.000208 0.000483 0.000150 0.000613 0.000097 0.000070 0.000117 0.000370 0.000153 0.000222
Bud Neck 0.005128 0.006938 0.002252 0.006398 0.011212 0.023214 0.004412 0.007194 0.008533 0.014299 0.003310 0.006900
Bud Site 0.002719 0.013432 0.008642 0.028703 0.009835 0.031948 0.006644 0.015104 0.006702 0.021805 0.007663 0.020135
Cell Periphery 0.000164 0.000090 0.000072 0.000161 0.000117 0.000111 0.000669 0.000047 0.000138 0.000100 0.000364 0.000089
Cytoplasm 0.641848 0.593631 0.707856 0.556628 0.533530 0.467282 0.613772 0.816657 0.581225 0.536493 0.661775 0.720445
Cytoplasmic Foci 0.170457 0.195717 0.017733 0.035022 0.251889 0.276861 0.042401 0.005626 0.216033 0.232412 0.029815 0.016503
Eisosomes 0.000126 0.000051 0.000020 0.000075 0.000117 0.000115 0.000738 0.000006 0.000121 0.000080 0.000372 0.000032
Endoplasmic Reticulum 0.000517 0.000875 0.001202 0.000815 0.001343 0.000425 0.000402 0.000065 0.000979 0.000672 0.000810 0.000343
Endosome 0.007269 0.029359 0.002147 0.008792 0.024121 0.054017 0.002823 0.001181 0.016701 0.040510 0.002478 0.003997
Golgi 0.001255 0.003710 0.000149 0.002309 0.005980 0.011528 0.000234 0.000697 0.003900 0.007245 0.000191 0.001293
Lipid Particles 0.003642 0.004187 0.000664 0.001804 0.006940 0.003194 0.001407 0.000144 0.005488 0.003738 0.001028 0.000758
Mitochondria 0.001901 0.001907 0.000363 0.004005 0.004856 0.008811 0.000199 0.001025 0.003555 0.005029 0.000283 0.002128
Mitotic Spindle 0.001108 0.002026 0.005966 0.037795 0.001013 0.002105 0.001926 0.013122 0.001055 0.002061 0.003987 0.022251
None 0.004966 0.003594 0.004397 0.003146 0.003032 0.000545 0.009794 0.006800 0.003884 0.002215 0.007040 0.005448
Nuclear Periphery 0.000244 0.000286 0.000635 0.000536 0.000222 0.000111 0.000325 0.000201 0.000232 0.000207 0.000483 0.000325
Nuclear Periphery Foci 0.000374 0.001564 0.001665 0.001025 0.000464 0.000308 0.000702 0.000056 0.000424 0.000996 0.001194 0.000414
Nucleolus 0.000772 0.001478 0.000190 0.000471 0.000717 0.000674 0.000859 0.000345 0.000741 0.001115 0.000518 0.000392
Nucleus 0.116663 0.040903 0.182746 0.127239 0.042032 0.012350 0.203591 0.091406 0.074894 0.027991 0.192956 0.104664
Peroxisomes 0.001266 0.002913 0.000294 0.000893 0.002739 0.009357 0.000339 0.000284 0.002091 0.005827 0.000316 0.000509
Vacuole 0.038250 0.094208 0.062618 0.180225 0.096550 0.092626 0.108528 0.039690 0.070879 0.093493 0.085104 0.091689
Vacuole Periphery 0.001256 0.002963 0.000181 0.003474 0.003140 0.003804 0.000137 0.000281 0.002311 0.003343 0.000159 0.001462

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.13 -4.51 -4.24 -2.85 -1.04 -1.73 1.14 4.71 2.07 2.32 -2.08 -3.03 -1.91 1.62 0.86
Bud Neck -1.79 4.13 0.88 2.54 -2.93 -6.18 7.49 6.41 9.99 -1.74 -5.39 8.86 5.64 9.56 -3.54
Bud Site -9.09 -3.76 -7.28 -1.90 -4.52 -9.08 2.57 1.70 10.26 -1.12 -11.36 0.06 -4.20 6.91 -3.85
Cell Periphery 5.95 7.04 4.58 -1.41 -3.02 0.63 -3.24 13.90 9.08 3.97 5.19 -2.51 11.76 7.62 3.91
Cytoplasm 5.07 1.32 13.49 7.76 11.78 6.09 -8.24 -26.41 -27.61 -16.32 6.05 -5.92 -11.14 -15.51 -5.08
Cytoplasmic Foci -3.65 36.00 33.00 32.11 -5.84 -3.07 41.92 51.14 41.71 19.96 -2.93 54.30 59.98 52.44 13.17
Eisosomes 11.04 15.14 10.00 -1.05 -8.01 0.30 -1.55 20.80 15.44 1.94 7.79 -1.19 22.54 14.77 1.89
Endoplasmic Reticulum -2.52 -8.43 -2.61 0.17 7.40 5.52 5.81 8.45 3.77 10.37 2.73 -1.71 6.01 4.17 11.70
Endosome -11.54 7.88 3.07 12.95 -3.49 -9.79 20.05 21.85 18.64 7.78 -13.34 21.01 20.23 23.04 0.82
Golgi -4.57 2.87 0.53 5.58 -2.62 -5.19 16.39 15.12 11.02 -0.64 -5.85 14.12 11.01 12.72 -2.48
Lipid Particles -0.95 10.98 5.19 4.70 -1.06 6.44 14.00 16.54 6.92 11.00 4.36 17.37 16.78 8.74 2.64
Mitochondria 0.02 2.05 0.13 0.14 -2.03 -2.25 5.83 5.20 5.25 -6.21 -1.58 5.87 4.02 5.09 -3.06
Mitotic Spindle -0.70 -3.19 -6.87 -6.40 -5.24 -1.61 -2.19 -6.66 -5.39 -4.42 -1.36 -3.96 -9.40 -8.18 -6.56
None 1.53 1.84 3.26 0.80 2.77 4.28 -3.47 -4.31 -16.32 1.51 2.90 -2.48 -1.74 -5.32 1.57
Nuclear Periphery -0.66 -12.74 -8.73 -8.95 2.85 2.65 -7.15 -9.98 -9.88 -5.68 0.69 -15.27 -12.59 -12.48 0.65
Nuclear Periphery Foci -3.07 -10.61 -6.49 1.29 5.99 2.22 -4.10 7.00 4.48 10.27 -2.64 -11.17 -0.35 2.58 11.45
Nucleolus -2.24 5.01 1.73 3.18 -1.38 0.18 0.08 4.48 1.55 0.80 -1.95 1.65 3.73 3.78 0.15
Nucleus 16.99 -15.28 -0.06 -14.78 14.09 16.10 -25.52 -25.73 -39.08 9.31 18.88 -29.33 -15.35 -32.94 17.04
Peroxisomes -4.15 4.56 3.28 7.01 -2.32 -5.92 9.96 10.45 8.42 2.71 -6.72 10.72 10.54 10.40 -0.24
Vacuole -15.06 -16.52 -31.27 -22.11 -19.93 0.80 -8.46 0.04 -0.74 8.35 -7.80 -15.35 -22.56 -15.73 -8.04
Vacuole Periphery -3.19 2.42 -0.35 3.20 -3.46 -1.64 13.17 12.96 11.12 -0.68 -3.21 9.10 6.07 10.80 -3.47
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Non-catalytic subunit of the NatC N-terminal acetyltransferase; required for replication of dsRNA virus; expression is glucose-repressible; human NatC ortholog, Naa35, requires co-expression of the human catalytic subunit, Naa30, to functionally complement the null allele
Localization
Cell Percentages cytoplasm (77%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Mak10

Mak10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mak10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available