Standard name
Human Ortholog
Description Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.05 – 0 0 0 0 0.08 0.1 0.11 0.06 0 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0.11 – 0 0.06 0 0.07 0 0 0 0 0 0 0 0 0 0 0.05 0.08
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.12 0 – 0.16 0.1 0.13 0.13 0.13 0.08 0 0.12 0.09 0.14 0 0 0 0.08 0.05 0.05
Nucleus 0.37 0.53 0.41 0 0.12 0.14 0.08 – 0.14 0.15 0.18 0.17 0 0.06 0.05 0.17 0.17 0.1 0.13 0.32 0.1 0.05 0 0.05
Nuclear Periphery 0.08 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.12 0 0.09 0 0.05 0.05
Nucleolus 0.51 0.44 0.55 0.96 0.82 0.81 0.8 – 0.71 0.75 0.69 0.7 0.89 0.82 0.81 0.69 0.78 0.76 0.66 0.6 0.71 0.62 0.53 0.51
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.21 0.17 0.19 0.28 – 0.16 0.18 0.14 0.15 0 0.07 0.09 0 0 0 0 0 0 0.1 0.16 0.11
Vac/Vac Membrane 0.1 0.06 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0.11 0.07 0 0 0.07 0 0 0.06 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 3 1 0 0 0 1 0 0 0 3 0 1 2 5 6
Bud Neck 0 0 0 3 0 1 1 – 0 2 0 1 0 8 5 0 0 0 0 0 0 0 2 3
Bud Site 1 0 0 0 0 5 1 – 10 10 6 10 0 0 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 2 0 2 3 7 15 – 6 5 8 3 24 44 58 7 3 5 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Endosome 1 0 0 2 6 0 32 – 3 15 10 21 3 12 12 1 1 0 4 0 0 6 26 37
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3
Mitochondria 0 2 1 2 2 19 10 – 33 27 31 37 42 36 21 14 8 10 2 0 2 19 25 24
Nucleus 72 61 44 2 16 22 25 – 28 39 41 49 12 29 25 19 15 7 30 42 14 12 20 23
Nuclear Periphery 16 2 6 0 3 2 4 – 6 3 6 7 0 0 0 0 1 0 28 1 12 7 26 22
Nucleolus 100 51 59 108 113 128 235 – 146 196 160 200 279 376 424 79 69 53 156 80 97 148 270 227
Peroxisomes 1 0 0 1 1 0 10 – 0 5 1 2 7 9 19 1 0 0 0 0 0 2 5 5
SpindlePole 1 0 0 23 23 30 82 – 33 48 32 44 13 31 47 0 1 0 3 0 1 23 82 48
Vac/Vac Membrane 19 7 6 0 5 0 4 – 2 4 3 6 1 4 4 13 6 3 7 8 6 10 28 31
Unique Cell Count 196 116 107 112 138 158 295 205 262 232 286 313 461 526 114 88 70 237 133 138 241 507 448
Labelled Cell Count 211 125 116 143 172 214 419 267 357 299 380 381 550 617 135 104 78 237 133 138 241 507 448


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 21.2 19.0 17.8 15.8 15.1 8.3 11.3 – 8.4 9.0 8.3 8.6 21.1 20.0 18.6 26.1 29.4 29.1 18.9 18.8 18.9
Std Deviation (1e-4) 5.7 5.0 3.9 5.1 4.2 2.8 3.3 – 2.3 2.8 2.6 2.5 7.9 9.2 8.9 13.4 11.7 13.0 4.4 6.3 6.2
Intensity Change (Log2) – – – -0.17 -0.23 -1.11 -0.65 – -1.08 -0.98 -1.09 -1.06 0.24 0.17 0.07 0.56 0.73 0.71 0.08 0.08 0.09


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 – 0 0 0 0 2.9 3.3 3.6 0 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 3.6 – 0 0 0 2.9 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.4 0 – 4.1 3.1 3.6 3.6 3.7 2.6 0 3.4 0 0
Nucleus -7.1 -5.3 -5.0 -7.7 – -5.5 -5.5 -4.6 -5.0 -9.8 -9.7 -11.0 -4.0 -3.6 -4.5
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 7.2 4.5 4.5 4.9 – 2.8 3.7 2.5 2.8 7.7 5.8 5.6 2.2 3.4 2.8
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 5.0 4.4 4.8 6.1 – 4.4 4.7 4.0 4.3 0 2.8 3.2 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 1.5 0.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 13.0427 14.9742 13.1755 9.8826 11.0285 13.2945 16.36 18.614 17.1871 15.6336 14.9452 16.9393 17.4431 20.8607 17.8169 16.5256 16.8125 18.6942
Actin 0.0149 0.0013 0.0005 0.0058 0.0184 0.0015 0.0017 0.0002 0.0171 0.0003 0.0411 0.0001 0.0106 0 0.0054 0 0.0211 0.0002
Bud 0.0003 0 0.0001 0.001 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001 0.0005 0 0.0002 0 0.0002 0 0.0009 0
Bud Neck 0.0002 0.0002 0.0002 0.0004 0.0012 0.0002 0.0002 0.0001 0.0001 0.0001 0.0003 0.0001 0.0004 0.0001 0.0001 0.0001 0.0002 0.0001
Bud Periphery 0.0006 0.0002 0.0003 0.0012 0.0008 0.0004 0.0002 0.0001 0.0005 0.0001 0.0007 0.0002 0.0004 0 0.0002 0.0001 0.0024 0.0002
Bud Site 0.0007 0.0002 0.0013 0.0024 0.0018 0.0001 0.0007 0.0001 0.0012 0.0002 0.0011 0.0001 0.0066 0.0001 0.0008 0.0001 0.0006 0.0001
Cell Periphery 0.0005 0.0007 0.0006 0.001 0.0013 0.0015 0.0005 0.0002 0.0002 0.0002 0.0003 0.0005 0.0006 0.0002 0.0002 0.0002 0.0006 0.0004
Cytoplasm 0.0009 0 0.0001 0.0003 0.0003 0 0.0079 0.0001 0.0007 0.0002 0.0014 0.0001 0.0015 0 0.0003 0 0.0004 0
Cytoplasmic Foci 0.006 0.0025 0.0041 0.0052 0.0062 0.0041 0.0058 0.0019 0.001 0.0049 0.0098 0.0033 0.0072 0.0005 0.0034 0.0012 0.0049 0.0014
Eisosomes 0.0002 0 0.0001 0.0002 0.0003 0.0002 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0001 0 0.0001 0 0.0002 0.0001
Endoplasmic Reticulum 0.0016 0 0.0001 0.0007 0.0006 0.0002 0.0006 0 0.0011 0.0001 0.0019 0.0001 0.0008 0 0.0001 0 0.0018 0.0001
Endosome 0.0197 0.0005 0.0035 0.0251 0.012 0.002 0.0081 0.0032 0.0084 0.0214 0.0288 0.0005 0.0073 0.0001 0.0002 0 0.0035 0.0001
Golgi 0.0076 0.0014 0.003 0.022 0.0136 0.0019 0.0008 0.0021 0.0025 0.0042 0.0065 0.0007 0.0025 0.0001 0.0003 0 0.0028 0.0004
Lipid Particles 0.0281 0.0055 0.0305 0.0491 0.0669 0.0632 0.0121 0.0015 0.0034 0.0064 0.012 0.0506 0.0163 0.0034 0.0069 0.0026 0.0128 0.0284
Mitochondria 0.0306 0.0027 0.0095 0.066 0.0169 0.0799 0.0136 0.0012 0.0066 0.0355 0.0133 0.0064 0.0119 0.0002 0.0075 0.0012 0.0143 0.021
None 0.001 0 0.0001 0.0006 0.0007 0.0002 0.0113 0.0001 0.0003 0.0003 0.0004 0.0002 0.0011 0 0.0006 0 0.0006 0.0001
Nuclear Periphery 0.0434 0.0177 0.0203 0.0041 0.1037 0.0499 0.0177 0.0165 0.0104 0.0557 0.038 0.0851 0.0079 0.0201 0.0131 0.0392 0.0315 0.042
Nucleolus 0.7626 0.8437 0.8454 0.719 0.5717 0.6579 0.7979 0.8512 0.8684 0.8081 0.6869 0.7358 0.8259 0.8474 0.8677 0.8397 0.7209 0.7961
Nucleus 0.0554 0.1013 0.0664 0.0536 0.1511 0.0723 0.0851 0.1171 0.0686 0.051 0.0972 0.0749 0.0784 0.1235 0.0822 0.1112 0.1423 0.0891
Peroxisomes 0.0028 0.0042 0.0018 0.0023 0.0077 0.0039 0.0009 0.0002 0.0002 0.0009 0.0022 0.0008 0.0026 0 0.0004 0.0001 0.0082 0.0003
Punctate Nuclear 0.0037 0.0014 0.0028 0.0138 0.0077 0.0056 0.02 0.0017 0.0008 0.0032 0.0522 0.0079 0.0118 0.0016 0.005 0.0009 0.0208 0.0066
Vacuole 0.004 0.0024 0.0023 0.0038 0.0063 0.0047 0.0021 0.0004 0.0022 0.0013 0.0015 0.0016 0.0017 0.0004 0.001 0.0006 0.0014 0.0009
Vacuole Periphery 0.0153 0.014 0.0069 0.0225 0.0107 0.0501 0.0125 0.002 0.0058 0.0056 0.0036 0.0308 0.0043 0.0023 0.0043 0.0028 0.0079 0.0123

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.3656 26.9269 33.6521 38.0288 58.5811 39.6118 18.6282 17.892 29.533 30.2584
Translational Efficiency 10.2875 9.3326 5.6821 6.7838 4.1685 4.0215 7.389 6.4137 4.3844 5.5952

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1555 1111 149 1555 1635 1870 2433 2073 3190 2981 2582 3628

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1453.90 1454.39 1774.26 2065.62 1383.11 1611.32 1907.02 2103.65 1417.62 1552.83 1899.36 2087.35
Standard Deviation 311.45 407.66 322.06 649.72 276.44 338.38 403.27 530.20 296.15 373.53 400.24 584.73
Intensity Change Log 2 — 0.000486 0.287289 0.506647 — 0.220327 0.463404 0.604979 — 0.111850 0.375836 0.555424

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000799 0.000816 0.000574 0.001461 0.000552 0.000655 0.000909 0.000928 0.000672 0.000715 0.000890 0.001156
Bud Neck 0.000828 0.002054 0.001871 0.007852 0.000958 0.001494 0.001830 0.008380 0.000895 0.001702 0.001832 0.008154
Bud Site 0.000136 0.000648 0.000239 0.001513 0.000210 0.000216 0.000152 0.002082 0.000174 0.000377 0.000157 0.001838
Cell Periphery 0.000015 0.000103 0.000012 0.000322 0.000021 0.000028 0.000025 0.000117 0.000018 0.000056 0.000025 0.000205
Cytoplasm 0.000533 0.001629 0.000013 0.000778 0.000306 0.000054 0.000042 0.001037 0.000416 0.000641 0.000040 0.000926
Cytoplasmic Foci 0.000963 0.004814 0.001058 0.009432 0.002050 0.001157 0.000427 0.004045 0.001521 0.002520 0.000463 0.006354
Eisosomes 0.000119 0.000181 0.000079 0.000285 0.000182 0.000204 0.000172 0.000175 0.000151 0.000196 0.000167 0.000222
Endoplasmic Reticulum 0.000381 0.000677 0.000233 0.000560 0.000420 0.000301 0.000200 0.000248 0.000401 0.000441 0.000202 0.000382
Endosome 0.000029 0.000130 0.000027 0.000447 0.000125 0.000135 0.000019 0.000315 0.000079 0.000133 0.000019 0.000372
Golgi 0.000076 0.000463 0.000210 0.000839 0.000168 0.000108 0.000076 0.000339 0.000123 0.000240 0.000084 0.000554
Lipid Particles 0.000030 0.000180 0.000043 0.000978 0.000317 0.000134 0.000014 0.000146 0.000177 0.000151 0.000016 0.000502
Mitochondria 0.001476 0.003228 0.002023 0.010675 0.002354 0.001943 0.002368 0.005674 0.001926 0.002422 0.002348 0.007818
Mitotic Spindle 0.000916 0.001562 0.005455 0.003426 0.001778 0.001178 0.000470 0.006850 0.001358 0.001321 0.000757 0.005383
None 0.000372 0.002374 0.000318 0.002118 0.000589 0.000568 0.000415 0.000876 0.000483 0.001241 0.000409 0.001408
Nuclear Periphery 0.013561 0.003887 0.005724 0.018178 0.006714 0.006182 0.008413 0.013495 0.010051 0.005326 0.008258 0.015502
Nuclear Periphery Foci 0.004785 0.003988 0.001792 0.010811 0.007266 0.003735 0.002199 0.004892 0.006056 0.003829 0.002176 0.007429
Nucleolus 0.720999* 0.682239* 0.764968* 0.669515* 0.766188* 0.701082* 0.671741* 0.659547* 0.744160* 0.694059* 0.677121* 0.663819*
Nucleus 0.234418* 0.246754* 0.176293* 0.185248* 0.171139* 0.254214* 0.286764* 0.248812* 0.201985* 0.251434* 0.280389* 0.221568*
Peroxisomes 0.012169 0.035770 0.037079 0.027179 0.035111 0.021959 0.013194 0.020079 0.023927 0.027106 0.014573 0.023122
Vacuole 0.000978 0.002191 0.000576 0.012478 0.001071 0.001053 0.001079 0.003493 0.001026 0.001477 0.001050 0.007344
Vacuole Periphery 0.006417 0.006314 0.001413 0.035903 0.002479 0.003598 0.009491 0.018470 0.004399 0.004611 0.009025 0.025942

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.40 3.66 -6.17 -5.49 -7.56 -1.33 -4.99 -5.29 -6.06 -0.97 -0.92 -4.89 -8.12 -7.95 -5.09
Bud Neck -4.11 -4.13 -15.20 -11.09 -11.92 -3.81 -6.15 -14.41 -13.36 -12.58 -5.62 -7.01 -20.16 -17.48 -16.98
Bud Site -2.78 -1.38 -9.28 -3.50 -8.08 -0.13 0.88 -4.30 -4.31 -4.44 -2.59 0.62 -6.13 -5.33 -6.25
Cell Periphery -2.37 1.77 -3.24 -2.17 -3.28 -1.28 -0.93 -6.19 -5.81 -6.07 -2.67 -2.06 -4.62 -3.55 -4.48
Cytoplasm -1.19 1.02 -0.33 1.17 -3.70 1.06 1.11 -1.70 -2.64 -2.67 -0.58 1.34 -1.32 -0.67 -3.83
Cytoplasmic Foci -2.91 0.31 -7.85 -3.45 -9.48 1.78 4.25 -4.25 -6.19 -8.47 -1.65 3.31 -8.69 -6.64 -13.54
Eisosomes -4.32 4.16 -7.14 -4.06 -8.92 -1.63 0.84 0.65 2.14 -0.22 -4.47 -1.55 -5.93 -1.92 -4.04
Endoplasmic Reticulum -2.20 2.49 -1.23 0.58 -2.12 1.07 1.94 1.37 1.08 -3.61 -0.43 3.25 0.13 0.57 -2.99
Endosome -4.20 0.40 -4.41 -3.28 -4.44 -0.13 1.64 -1.71 -1.64 -3.05 -1.08 1.78 -3.87 -3.06 -5.08
Golgi -1.81 -4.52 -5.89 -1.56 -4.76 1.51 2.41 -4.03 -8.66 -10.92 -1.40 1.98 -7.20 -3.32 -8.28
Lipid Particles -1.66 -0.55 -2.73 -2.20 -2.69 1.12 1.97 1.04 -0.29 -4.48 0.24 2.04 -1.95 -2.24 -3.27
Mitochondria -4.94 -1.80 -10.93 -8.27 -9.80 0.89 -0.05 -6.26 -9.33 -9.02 -1.70 -1.69 -12.74 -12.06 -12.71
Mitotic Spindle -0.84 -1.48 -2.80 -2.24 0.64 1.06 3.37 -5.10 -5.56 -6.60 0.10 1.62 -5.83 -5.96 -7.07
None -4.33 1.38 -9.52 0.55 -9.84 0.12 0.91 -1.48 -2.11 -5.13 -3.49 0.70 -6.95 -0.82 -9.96
Nuclear Periphery 5.57 2.37 -1.84 -7.01 -3.55 0.37 -1.22 -3.75 -4.09 -2.85 4.11 1.41 -3.58 -7.52 -4.87
Nuclear Periphery Foci 0.81 3.85 -5.02 -5.34 -7.83 3.24 5.36 2.41 -1.37 -4.93 3.07 6.55 -1.71 -5.06 -9.20
Nucleolus 4.06 -2.52 5.79 1.35 5.54 8.91 12.84 14.56 5.90 2.28 8.52 10.17 14.19 5.46 2.50
Nucleus -1.35 3.40 6.02 6.67 -0.55 -11.81 -16.30 -11.30 0.15 4.28 -8.67 -12.13 -4.05 4.56 8.40
Peroxisomes -12.04 -5.55 -9.90 3.53 2.20 7.66 13.94 8.48 1.16 -7.19 -2.61 9.14 0.36 3.03 -9.04
Vacuole -4.55 2.68 -10.67 -9.44 -11.09 0.06 -0.07 -7.86 -7.23 -8.43 -2.42 -0.19 -12.67 -11.49 -12.69
Vacuole Periphery 0.08 4.74 -11.75 -12.03 -15.10 -2.08 -8.19 -10.06 -9.17 -5.01 -0.31 -5.02 -15.02 -15.23 -11.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis
Localization
Cell Percentages nucleolus (37%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-2

Nop16

Nop16


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nop16-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available