Standard name
Human Ortholog
Description Mannose-6-phosphate isomerase; catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.99 0.98 0.94 0.96 0.88 0.78 0.87 0.83 0.86 0.85 1.0 0.99 0.99 0.97 0.99 0.98 0.95 0.95 0.88 0.95 0.96 0.94
Endoplasmic Reticulum 0 0 0 0 0 0 0.05 0.06 0.05 0.06 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.06 0.05 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.07 0 0.06 0.14 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 1 0 5 3 6 0 0 0 0 0 0 0 1 0 2 0 0 0
Bud 1 0 0 1 0 0 0 3 1 2 0 1 1 0 0 2 0 0 3 5 1 2 4 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 6 1 1 2 2 3 8 4 9 13 6 10 0 3 1 3 3 3 2 0 0 0 0 0
Cytoplasm 311 202 158 258 222 347 373 320 287 326 237 310 367 595 591 455 308 230 304 197 142 208 444 432
Endoplasmic Reticulum 0 3 1 1 0 9 22 23 17 23 11 22 0 4 0 13 11 7 0 1 4 0 1 4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 1 2 1 0 0
Golgi 0 0 0 0 0 0 0 2 2 0 1 0 0 0 0 0 0 0 0 0 2 0 2 0
Mitochondria 2 1 1 0 1 5 10 8 21 21 17 24 0 0 0 6 2 2 0 0 0 0 0 0
Nucleus 2 0 0 0 0 2 2 2 1 3 1 2 0 0 1 2 1 0 0 0 1 0 1 3
Nuclear Periphery 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Vac/Vac Membrane 2 0 1 5 16 2 27 58 4 22 9 9 1 2 4 16 4 4 1 1 2 0 1 4
Unique Cell Count 316 206 159 264 235 361 425 411 329 393 277 365 368 601 594 470 310 234 320 209 163 220 461 461
Labelled Cell Count 325 207 162 267 241 369 443 424 347 413 289 378 369 604 597 497 330 246 320 209 163 220 461 461


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.7 18.0 14.7 14.6 16.3 16.8 16.2 17.0 18.4 18.1 18.6 19.6 19.1 19.7 19.2 18.1 24.3 24.4 14.0 13.3 13.2
Std Deviation (1e-4) 3.3 4.4 4.5 3.8 4.1 3.9 4.7 4.3 5.6 4.7 5.5 5.5 5.8 6.1 5.8 6.2 8.1 7.5 3.4 2.9 2.8
Intensity Change (Log2) – – – -0.01 0.15 0.19 0.14 0.21 0.32 0.3 0.34 0.41 0.38 0.42 0.38 0.3 0.72 0.73 -0.07 -0.15 -0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.3 -2.6 -2.0 -4.3 -6.3 -4.4 -5.3 -4.8 -4.9 0.6 -0.4 0.2 -1.8 0 -0.9
Endoplasmic Reticulum 0 0 0 2.5 2.6 2.5 2.7 0 2.8 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 2.9 2.6 2.8 2.9 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 3.0 0 2.9 4.7 0 2.6 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.0913 13.0081 12.2236 11.8633 11.7403 12.9545 10.1777 14.5029 14.4639 14.846 13.1128 13.1788 14.6923 21.1129 18.9081 18.4737 17.5698 17.2217
Actin 0.0393 0.0005 0.0044 0.0003 0.0003 0.0001 0.0071 0.0007 0.0041 0.0336 0.0287 0.0007 0.004 0.0008 0.0022 0.0001 0.0009 0.0007
Bud 0.0009 0.0002 0.0006 0.0001 0.0002 0.0001 0.0007 0.0033 0.0002 0.0003 0.0002 0.0001 0.0008 0.0001 0.0007 0 0.0003 0.0002
Bud Neck 0.0035 0.0002 0.0008 0.0006 0.0007 0.0014 0.0005 0.0002 0.0018 0.0004 0.0007 0.0008 0.0005 0.0001 0.0003 0.0003 0.0004 0.0008
Bud Periphery 0.0006 0 0.0002 0 0 0 0.0009 0.0007 0.0001 0.0003 0.0002 0.0001 0.0005 0 0.0002 0 0.0001 0
Bud Site 0.004 0.0005 0.0009 0 0.0001 0 0.0006 0.0005 0.001 0.0007 0.0003 0.0001 0.0033 0.0003 0.0004 0 0.0001 0
Cell Periphery 0.0004 0.0001 0.0001 0 0 0 0.0001 0 0.0001 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.8164 0.9829 0.97 0.9849 0.9761 0.9747 0.9043 0.9769 0.9558 0.9159 0.907 0.9729 0.9385 0.9924 0.9751 0.992 0.9777 0.9775
Cytoplasmic Foci 0.0109 0.001 0.0031 0.0008 0.0013 0.0007 0.0199 0.0013 0.0087 0.0077 0.0099 0.0037 0.0078 0.0011 0.0029 0.0005 0.0012 0.0028
Eisosomes 0.0005 0 0 0 0 0 0.0001 0 0.0002 0.0001 0.0002 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0074 0.0015 0.0012 0.0013 0.0021 0.001 0.0031 0.0019 0.0013 0.0005 0.0011 0.0016 0.0026 0.0004 0.0006 0.0008 0.0041 0.0011
Endosome 0.0171 0.0006 0.0032 0.0003 0.0008 0.0007 0.0082 0.0026 0.0036 0.0018 0.0033 0.0024 0.006 0.0002 0.0015 0.0002 0.0017 0.0006
Golgi 0.0037 0.0001 0.001 0 0.0001 0 0.0026 0.0002 0.0015 0.0038 0.004 0.0007 0.001 0.0001 0.0013 0 0.0001 0
Lipid Particles 0.0063 0 0.0008 0 0 0 0.0056 0.0002 0.0033 0.0007 0.0104 0.0009 0.0033 0 0.001 0 0.0001 0
Mitochondria 0.0038 0.0001 0.0014 0.0001 0.0001 0.0001 0.0095 0.0004 0.0005 0.0024 0.002 0.0035 0.0024 0.0001 0.0017 0 0.0002 0.0001
None 0.0104 0.0028 0.0012 0.0006 0.001 0.0005 0.0177 0.0017 0.0032 0.0012 0.0015 0.0012 0.0037 0.0008 0.0009 0.0004 0.0012 0.0012
Nuclear Periphery 0.0221 0.0016 0.0016 0.0015 0.0038 0.0024 0.0023 0.0036 0.0008 0.0005 0.0013 0.0011 0.0031 0.0004 0.0009 0.0008 0.0019 0.0015
Nucleolus 0.0019 0 0.0001 0 0 0 0.0002 0.0001 0.0004 0 0.0001 0 0.0002 0 0.0013 0 0 0
Nucleus 0.0287 0.0065 0.0072 0.0086 0.012 0.0167 0.0067 0.0044 0.0052 0.0035 0.0093 0.0075 0.0095 0.0027 0.0075 0.0044 0.009 0.0118
Peroxisomes 0.0026 0 0.0005 0 0 0 0.0051 0 0.0057 0.0258 0.0176 0.0015 0.0064 0 0.0005 0 0 0
Punctate Nuclear 0.0115 0.0002 0.0008 0.0003 0.0003 0.0001 0.0022 0.0004 0.0019 0.0005 0.0018 0.0006 0.0044 0.0001 0.0007 0.0001 0.0003 0.0009
Vacuole 0.006 0.001 0.0008 0.0005 0.0009 0.0012 0.002 0.0005 0.0007 0.0002 0.0003 0.0003 0.0016 0.0001 0.0003 0.0002 0.0006 0.0003
Vacuole Periphery 0.002 0.0001 0.0002 0.0001 0.0002 0.0003 0.0006 0.0003 0.0002 0 0.0001 0.0001 0.0004 0 0.0001 0 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 201.8631 192.6874 137.3085 113.0787 159.6962 176.9599 173.5653 133.8426 102.55 167.6201
Translational Efficiency 1.5927 1.5987 1.3356 1.4594 1.9585 1.8274 1.7234 1.4084 1.718 1.8021

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1029 1236 2108 1335 1537 1374 1190 97 2566 2610 3298 1432

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1411.74 1138.71 2075.54 1790.17 1232.76 1135.25 2285.57 1648.48 1304.53 1136.89 2151.32 1780.57
Standard Deviation 304.02 225.78 435.76 415.35 260.77 229.71 475.13 401.13 292.39 227.87 461.52 415.93
Intensity Change Log 2 — -0.310074 0.556012 0.342622 — -0.118882 0.890662 0.419244 — -0.217788 0.721700 0.378847

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000432 0.000173 0.000098 0.003088 0.000305 0.000476 0.000164 0.000581 0.000356 0.000333 0.000122 0.002918
Bud Neck 0.000670 0.000726 0.000944 0.001821 0.000601 0.001367 0.001278 0.001931 0.000628 0.001063 0.001065 0.001828
Bud Site 0.003600 0.005198 0.002130 0.010829 0.003443 0.009405 0.001650 0.021543 0.003506 0.007413 0.001957 0.011555
Cell Periphery 0.000101 0.000048 0.000114 0.000170 0.000112 0.000045 0.000194 0.001179 0.000107 0.000046 0.000143 0.000238
Cytoplasm 0.861706* 0.870463* 0.746148* 0.765189* 0.872236* 0.867651* 0.700172* 0.594841* 0.868013* 0.868982* 0.729558* 0.753650*
Cytoplasmic Foci 0.014008 0.020115 0.004093 0.010052 0.011041 0.030344 0.006585 0.035629 0.012231 0.025500 0.004992 0.011785
Eisosomes 0.000003 0.000005 0.000001 0.000004 0.000003 0.000007 0.000002 0.000017 0.000003 0.000006 0.000001 0.000005
Endoplasmic Reticulum 0.000331 0.000308 0.000081 0.000909 0.000741 0.000318 0.000112 0.000251 0.000577 0.000313 0.000092 0.000864
Endosome 0.000855 0.001683 0.000171 0.004868 0.000658 0.002531 0.000288 0.001358 0.000737 0.002129 0.000213 0.004630
Golgi 0.001018 0.001169 0.000183 0.006133 0.000612 0.001859 0.000377 0.000326 0.000775 0.001532 0.000253 0.005739
Lipid Particles 0.000186 0.000304 0.000250 0.000885 0.000266 0.000339 0.000568 0.001057 0.000234 0.000322 0.000365 0.000897
Mitochondria 0.000159 0.000857 0.000199 0.002015 0.000623 0.000959 0.000179 0.000371 0.000437 0.000911 0.000192 0.001904
Mitotic Spindle 0.002353 0.004879 0.004526 0.022601 0.002385 0.008784 0.004594 0.018427 0.002372 0.006935 0.004551 0.022319
None 0.010023 0.007744 0.010419 0.006216 0.009017 0.006161 0.009355 0.010820 0.009420 0.006911 0.010035 0.006528
Nuclear Periphery 0.000090 0.000075 0.000209 0.000326 0.000067 0.000099 0.000281 0.000302 0.000076 0.000088 0.000235 0.000324
Nuclear Periphery Foci 0.001748 0.001861 0.000617 0.001876 0.001902 0.001274 0.001422 0.002220 0.001840 0.001552 0.000907 0.001899
Nucleolus 0.000228 0.000157 0.000119 0.000193 0.000096 0.000245 0.000129 0.000256 0.000149 0.000203 0.000123 0.000198
Nucleus 0.096897 0.063400 0.221027* 0.134830* 0.088692 0.038882 0.254630* 0.107453 0.091983 0.050493 0.233152* 0.132975*
Peroxisomes 0.000285 0.000425 0.000019 0.000859 0.000062 0.000641 0.000022 0.000158 0.000151 0.000539 0.000020 0.000812
Vacuole 0.004900 0.020119 0.008571 0.024761 0.006155 0.027955 0.017896 0.201097* 0.005652 0.024244 0.011936 0.036705
Vacuole Periphery 0.000407 0.000291 0.000079 0.002375 0.000984 0.000658 0.000102 0.000186 0.000753 0.000484 0.000087 0.002227

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.03 1.08 -1.17 -1.77 -1.79 -0.72 0.26 -1.33 -0.09 -1.48 0.32 1.43 -1.41 -1.50 -1.74
Bud Neck -0.49 -7.21 -6.83 -6.82 -1.14 -3.03 -8.80 -5.28 -3.67 -1.69 -2.95 -10.94 -8.20 -5.40 -0.56
Bud Site -1.76 0.75 -3.29 -1.75 -4.22 -4.29 0.53 -4.67 -2.85 -4.78 -4.59 0.94 -4.73 -0.77 -5.35
Cell Periphery 6.14 -5.07 -4.71 -8.92 0.81 6.91 -9.43 -3.46 -3.93 -1.95 9.03 -9.35 -5.51 -9.61 1.82
Cytoplasm 0.94 26.29 18.61 17.25 -3.95 2.86 33.54 11.58 10.91 3.63 2.93 42.79 24.22 21.07 -5.26
Cytoplasmic Foci -4.18 5.63 1.63 5.66 -4.26 -11.27 -0.63 -4.47 1.13 -4.27 -11.46 4.14 -0.42 10.31 -3.85
Eisosomes -4.06 0.68 -3.97 1.52 -8.25 -5.82 -2.21 -6.46 -4.61 -6.13 -6.94 0.16 -6.89 1.35 -8.51
Endoplasmic Reticulum -0.14 5.79 0.25 0.30 -1.23 3.37 6.53 5.48 0.84 -1.19 3.32 8.12 1.97 0.23 -1.14
Endosome -1.71 2.01 -1.24 0.25 -2.90 -3.95 1.65 -2.81 1.91 -3.86 -4.20 2.93 -1.79 1.14 -2.93
Golgi -0.06 2.28 -0.79 -0.68 -1.97 -1.78 1.80 2.92 2.32 2.11 -1.44 3.13 -1.14 -0.24 -1.87
Lipid Particles -2.02 -7.73 -8.00 -6.78 -4.30 -0.64 -11.36 -3.64 -3.52 -1.59 -1.51 -12.38 -8.31 -7.48 -3.32
Mitochondria -0.93 -1.96 -1.44 0.23 -1.18 -0.41 1.05 0.85 1.39 -0.73 -0.85 0.88 -0.38 0.51 -1.22
Mitotic Spindle -1.70 -4.17 -5.02 -3.23 -2.84 -3.06 -3.17 -2.96 -1.87 -2.18 -3.47 -5.26 -5.58 -3.00 -3.27
None 2.28 1.01 4.63 2.10 9.33 3.77 2.80 4.37 1.21 2.96 4.16 1.93 7.12 1.76 8.96
Nuclear Periphery 0.15 -14.05 -7.58 -8.47 2.19 -1.52 -19.39 -6.89 -6.33 -1.98 -1.39 -24.69 -10.15 -8.87 2.78
Nuclear Periphery Foci -0.47 2.61 -0.05 0.52 -3.89 2.32 -1.70 -1.47 -2.18 -0.89 1.17 1.75 -0.05 -1.20 -1.76
Nucleolus 1.07 1.04 0.94 -0.41 -0.37 -1.80 -4.59 -2.13 0.43 -0.29 -0.56 -0.19 -0.29 0.43 -0.25
Nucleus 7.05 -27.85 -8.40 -16.84 19.42 14.87 -28.96 1.99 -2.70 17.09 14.74 -41.56 -10.60 -21.83 24.19
Peroxisomes -0.40 1.23 0.08 0.61 -1.65 -4.88 2.39 -4.19 4.04 -5.69 -2.81 1.41 -0.66 1.46 -1.67
Vacuole -9.53 -11.83 -20.15 -11.64 -13.27 -12.91 -15.46 -10.06 -9.03 -8.09 -15.89 -19.49 -21.39 -14.02 -12.32
Vacuole Periphery 1.03 2.59 -1.02 -1.71 -2.53 1.13 2.94 2.80 2.31 -1.78 1.51 3.56 0.38 -0.88 -2.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mannose-6-phosphate isomerase; catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation
Localization
Cell Percentages cytoplasm (98%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Pmi40

Pmi40


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pmi40-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available