Standard name
Human Ortholog
Description Microtubule plus end-tracking protein; together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally; homolog of human end binding protein 1 (EB1)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0.05 0 0 0 0 0.05 0 0 0.06 0.07 0.07 0.07 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0 0 0.05 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.24 0 0.08 0.15 0.17 0.17 0.12 0.06 0 0.05 0 0.05 0.28 0.35 0.39 0.28 0.2 0.26 0.17 0.14 0.18 0.19 0.15 0.15
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.22 0.41 0.11 0.1 0.06 0.23 0.28 0.25 0.38 0.33 0.46 0.37 0 0 0 0.09 0.06 0.07 0 0.07 0 0.07 0 0
Nucleus 0 0 0.08 0.12 0.05 0.11 0.09 0.11 0.12 0.12 0.14 0.11 0 0 0 0 0 0.05 0 0.06 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.43 0.51 0.42 0.34 0.46 0.39 0.45 0.43 0.46 0.47 0.45 0.52 0.52 0.48 0.42 0.59 0.63 0.64 0 0.1 0 0.05 0 0
Peroxisomes 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.13 0.07 0.07 0 0.06 0 0 0 0.1 0.08
SpindlePole 0.55 0.13 0.6 0.59 0.64 0.44 0.41 0.4 0.28 0.35 0.28 0.29 0.61 0.65 0.58 0.39 0.47 0.35 0.55 0.43 0.6 0.5 0.53 0.55
Vac/Vac Membrane 0 0.15 0 0.06 0 0.08 0 0 0 0 0 0 0 0 0.05 0.11 0.09 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 1 1 0 0 0 1 0 2 0 0 0 0 0 0 0 0 2 0 0 2 4 3
Bud 3 0 1 2 0 1 7 11 6 4 9 7 2 0 0 2 2 1 4 5 1 1 4 11
Bud Neck 3 1 1 2 6 4 5 10 5 6 9 6 2 0 0 1 3 0 2 2 3 2 5 3
Bud Site 13 0 0 4 2 10 14 12 14 16 18 16 2 2 3 0 2 3 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 9 4 1 8 17 8 14 16 7 8 7 8 3 8 17 6 3 7 0 2 0 0 3 1
Endoplasmic Reticulum 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 2 1 3 0 0 0 0 0 1
Endosome 69 4 4 29 52 38 42 22 9 11 7 11 51 90 103 44 25 46 51 15 18 25 38 50
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 1
Mitochondria 63 40 6 20 18 51 95 84 88 74 126 89 6 0 2 15 8 13 11 8 2 9 11 6
Nucleus 12 3 4 24 15 24 32 37 27 26 39 26 8 7 9 7 2 8 4 6 1 1 3 5
Nuclear Periphery 0 2 0 1 0 0 6 2 0 3 4 1 0 0 2 0 2 1 0 0 0 0 1 1
Nucleolus 123 50 22 65 140 87 150 147 105 106 123 126 96 124 112 94 80 112 10 11 3 6 8 12
Peroxisomes 23 0 2 8 4 7 14 7 6 5 1 1 3 17 35 11 9 7 19 2 0 5 25 26
SpindlePole 155 13 32 113 198 97 139 137 64 78 75 70 113 170 153 62 59 62 169 48 61 67 140 182
Vac/Vac Membrane 7 15 1 11 13 17 5 2 8 5 1 6 4 5 14 17 11 12 3 4 3 1 0 2
Unique Cell Count 284 98 53 193 307 222 337 339 229 224 272 241 185 260 265 158 126 176 310 113 102 135 265 332
Labelled Cell Count 481 133 75 289 465 344 523 489 339 344 419 368 290 423 451 261 207 276 310 113 102 135 265 332


Microtubule

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 6.2 6.5 6.2 6.8 5.5 5.3 5.9 5.1 5.4 5.0 5.1 7.0 7.6 7.5 9.2 10.4 10.5 6.2 6.9 7.4
Std Deviation (1e-4) 0.8 0.9 1.1 1.2 1.3 1.0 1.3 1.3 1.1 1.2 1.2 1.0 0.9 1.3 1.6 1.9 2.1 2.4 1.4 1.1 1.3
Intensity Change (Log2) – – – -0.07 0.06 -0.23 -0.29 -0.13 -0.37 -0.28 -0.39 -0.35 0.1 0.22 0.2 0.5 0.67 0.69 -0.08 0.08 0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 1.4 1.7 1.7 1.0 0 0 0 0 0 3.0 3.9 4.4 3.1 2.0 2.9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.2 0 1.9 2.6 2.2 3.8 3.1 4.7 3.6 0 0 0 -0.4 0 0
Nucleus 1.0 0 0.7 0 0.7 0.9 0.9 1.3 0.7 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.1 0.6 -0.3 0.4 0.3 0.6 0.8 0.5 1.4 1.3 0.8 0.1 2.3 2.7 2.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 2.0 0 0 0
SpindlePole -0.2 0.6 -2.2 -2.6 -2.7 -4.5 -3.4 -4.6 -4.3 0.1 0.7 -0.4 -2.7 -1.7 -3.3
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.7303 4.7556 4.815 4.3658 3.6397 4.1399 3.3026 4.7597 4.5442 3.8224 3.348 4.065 1.656 2.8058 2.7188 2.6369 1.7366 2.2479
Actin 0.0106 0.0005 0.0084 0.0015 0.007 0.0095 0.0244 0.0007 0.0026 0.0013 0.0288 0.0111 0.0148 0.0005 0.0005 0.0013 0.0486 0.0271
Bud 0.0002 0.0003 0.0002 0.0001 0.0006 0.0004 0.0003 0.0004 0.0001 0.0006 0.0007 0.0004 0.0006 0.0009 0.0003 0.0002 0.0015 0.0008
Bud Neck 0.0009 0.0026 0.001 0.0002 0.0011 0.0127 0.002 0.0018 0.0009 0.0034 0.0018 0.0059 0.0043 0.0025 0.0046 0.0024 0.0104 0.0233
Bud Periphery 0.0004 0.0002 0.0003 0.0002 0.0009 0.0008 0.0007 0.0005 0.0003 0.0014 0.0021 0.0013 0.001 0.0009 0.0006 0.0003 0.0031 0.0036
Bud Site 0.0015 0.0025 0.0017 0.0002 0.0028 0.0023 0.0031 0.0126 0.0009 0.005 0.0027 0.0017 0.0098 0.0081 0.0026 0.0013 0.0087 0.0017
Cell Periphery 0.0001 0 0.0001 0 0.0001 0.0002 0.0002 0.0001 0 0.0007 0.0003 0.0002 0.0003 0.0002 0.0001 0.0001 0.0005 0.0011
Cytoplasm 0.0045 0.0123 0.0009 0.0001 0.0014 0.0014 0.0029 0.0002 0.0002 0.0015 0.0014 0.0015 0.002 0.0022 0.0004 0.0001 0.0013 0.0036
Cytoplasmic Foci 0.051 0.0205 0.0299 0.0537 0.0802 0.0247 0.0493 0.0157 0.0227 0.067 0.0347 0.0294 0.083 0.0221 0.0309 0.0829 0.0549 0.0371
Eisosomes 0.0003 0 0.0001 0 0.0001 0.0002 0.0004 0 0.0001 0.0001 0.0007 0.0002 0.0005 0 0 0.0001 0.0009 0.0003
Endoplasmic Reticulum 0.0008 0.0002 0.0006 0.0001 0.0015 0.0011 0.0011 0 0.0001 0.0055 0.0011 0.0008 0.0006 0.0004 0 0.0001 0.0004 0.0014
Endosome 0.0152 0.0012 0.0108 0.0032 0.0722 0.0105 0.0131 0.002 0.0022 0.0465 0.0203 0.0174 0.019 0.0049 0.0008 0.0042 0.0385 0.0195
Golgi 0.008 0.0019 0.0036 0.0045 0.0282 0.009 0.008 0.0021 0.0032 0.0086 0.0188 0.0075 0.0126 0.0034 0.0014 0.0084 0.0536 0.0133
Lipid Particles 0.0839 0.0236 0.0252 0.0753 0.2769 0.0953 0.0706 0.0266 0.0295 0.1498 0.2519 0.0649 0.0818 0.059 0.0164 0.1604 0.2915 0.0975
Mitochondria 0.0029 0.0001 0.0048 0.0469 0.0082 0.0217 0.0034 0.0002 0.0121 0.0062 0.1823 0.023 0.0322 0.0006 0.001 0.0135 0.1477 0.0216
None 0.0023 0.0028 0.0008 0.0001 0.0008 0.0007 0.0033 0.0001 0.0003 0.0016 0.0063 0.0005 0.0014 0.0005 0.0004 0.0003 0.0013 0.0008
Nuclear Periphery 0.017 0.0036 0.0087 0.0016 0.0222 0.0261 0.0122 0.0028 0.0014 0.0183 0.0106 0.0143 0.0144 0.0077 0.0021 0.0023 0.0032 0.0292
Nucleolus 0.0447 0.1205 0.0735 0.0071 0.0096 0.0944 0.084 0.1551 0.0787 0.1207 0.1221 0.0846 0.0471 0.1577 0.1149 0.0674 0.0727 0.0391
Nucleus 0.0158 0.0464 0.0134 0.0014 0.0028 0.0795 0.0362 0.0593 0.0161 0.0089 0.0188 0.0604 0.0223 0.0919 0.0161 0.0067 0.0253 0.1469
Peroxisomes 0.0132 0.005 0.0059 0.0085 0.0863 0.0226 0.0215 0.0078 0.0167 0.0439 0.1397 0.016 0.0271 0.0068 0.0112 0.0744 0.1539 0.0399
Punctate Nuclear 0.7256 0.7555 0.8094 0.7946 0.3906 0.5845 0.6617 0.7116 0.8114 0.4895 0.1482 0.6546 0.6228 0.6279 0.7953 0.573 0.0771 0.4859
Vacuole 0.0007 0.0003 0.0006 0.0002 0.0043 0.0013 0.001 0.0003 0.0002 0.017 0.0031 0.003 0.0014 0.0016 0.0002 0.0004 0.0031 0.004
Vacuole Periphery 0.0005 0.0001 0.0004 0.0004 0.0021 0.0013 0.0008 0.0001 0.0002 0.0026 0.0037 0.0012 0.0009 0.0004 0.0001 0.0003 0.0018 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.0531 14.2953 14.8508 20.5446 44.9226 12.786 18.5493 15.9339 19.0111 31.1166
Translational Efficiency 1.6464 1.6668 0.7986 0.8603 0.8612 2.8985 1.2334 1.0292 1.1052 1.1332

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2256 564 2193 416 1458 1184 58 968 3714 1748 2251 1384

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 837.90 964.20 984.89 1071.50 802.54 899.95 1174.75 1078.83 824.02 920.68 989.78 1076.63
Standard Deviation 102.88 158.42 139.48 178.75 108.50 131.05 127.97 177.11 106.53 143.64 142.41 177.63
Intensity Change Log 2 — 0.202554 0.233185 0.354782 — 0.165272 0.549709 0.426822 — 0.184435 0.396708 0.390475

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000757 0.002487 0.000337 0.000899 0.001049 0.001199 0.003442 0.001743 0.000872 0.001615 0.000417 0.001489
Bud Neck 0.006904 0.007938 0.004445 0.010184 0.006256 0.006859 0.012366 0.009419 0.006650 0.007207 0.004649 0.009649
Bud Site 0.006825 0.011702 0.004060 0.023038 0.008033 0.007938 0.020158 0.016440 0.007300 0.009152 0.004475 0.018424
Cell Periphery 0.000168 0.000156 0.000036 0.000166 0.000179 0.000137 0.000182 0.000120 0.000172 0.000143 0.000040 0.000134
Cytoplasm 0.007029 0.012925 0.002613 0.011015 0.006977 0.010053 0.014066 0.006509 0.007008 0.010980 0.002908 0.007864
Cytoplasmic Foci 0.050571 0.032183 0.002514 0.023340 0.040074 0.028918 0.009710 0.010920 0.046450 0.029972 0.002700 0.014653
Eisosomes 0.000081 0.000070 0.000011 0.000024 0.000090 0.000060 0.000073 0.000023 0.000085 0.000063 0.000013 0.000023
Endoplasmic Reticulum 0.001575 0.002467 0.000401 0.000572 0.002027 0.001936 0.003733 0.000788 0.001752 0.002107 0.000487 0.000723
Endosome 0.012375 0.007713 0.001019 0.009667 0.008795 0.010610 0.005722 0.006670 0.010970 0.009676 0.001140 0.007571
Golgi 0.009038 0.006724 0.000922 0.008024 0.010083 0.007610 0.001759 0.005119 0.009448 0.007324 0.000944 0.005992
Lipid Particles 0.051656 0.017664 0.000973 0.000597 0.042733 0.020672 0.003719 0.001107 0.048153 0.019701 0.001044 0.000953
Mitochondria 0.005775 0.003141 0.001369 0.006430 0.003932 0.006523 0.002641 0.012464 0.005051 0.005432 0.001401 0.010650
Mitotic Spindle 0.657846 0.754047 0.948965 0.852053 0.688295 0.769894 0.782583 0.882187 0.669799 0.764781 0.944678 0.873130
None 0.002558 0.001545 0.000522 0.000892 0.002140 0.001505 0.000771 0.000783 0.002394 0.001518 0.000528 0.000816
Nuclear Periphery 0.000885 0.000841 0.000555 0.000559 0.000745 0.000764 0.000657 0.000812 0.000830 0.000789 0.000558 0.000736
Nuclear Periphery Foci 0.056641 0.052157 0.005229 0.001507 0.063646 0.038780 0.020188 0.003377 0.059391 0.043096 0.005614 0.002815
Nucleolus 0.047736 0.029661 0.011926 0.016624 0.043202 0.035261 0.016247 0.009295 0.045956 0.033454 0.012037 0.011498
Nucleus 0.012750 0.021564 0.009480 0.012261 0.015670 0.018323 0.029065 0.011374 0.013896 0.019369 0.009984 0.011641
Peroxisomes 0.066880 0.031922 0.003550 0.009439 0.054493 0.029059 0.063180 0.008117 0.062017 0.029983 0.005086 0.008515
Vacuole 0.001551 0.002604 0.000851 0.008866 0.001326 0.002551 0.009173 0.008096 0.001463 0.002568 0.001065 0.008327
Vacuole Periphery 0.000399 0.000490 0.000222 0.003844 0.000256 0.001347 0.000565 0.004637 0.000343 0.001071 0.000231 0.004399

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.84 3.85 -1.92 2.23 -3.28 -0.85 -2.53 -2.27 -1.95 1.69 -3.36 4.14 -2.95 -0.20 -3.88
Bud Neck -1.76 -0.13 -5.10 -3.63 -4.97 -1.96 -2.34 -6.65 -5.29 -0.10 -2.39 -0.89 -8.26 -6.38 -7.19
Bud Site -4.03 1.57 -5.91 -3.78 -6.22 -1.10 -2.84 -6.55 -5.77 0.34 -3.69 1.55 -9.13 -6.76 -9.54
Cell Periphery -0.61 12.03 -0.35 -0.12 -3.16 2.28 -1.11 2.47 0.35 1.81 1.68 13.96 1.38 0.21 -5.55
Cytoplasm -2.04 3.43 -2.22 -0.54 -3.27 -1.81 -1.62 -1.13 0.68 1.36 -2.61 3.32 -2.27 0.21 -4.14
Cytoplasmic Foci 5.02 21.69 5.80 1.25 -6.28 3.70 10.15 8.84 4.83 -2.41 7.21 26.25 12.56 4.68 -8.59
Eisosomes 1.84 27.29 15.54 5.73 -4.87 6.75 0.38 16.34 9.56 3.18 6.48 30.88 24.07 10.88 -5.40
Endoplasmic Reticulum -4.37 12.47 4.87 6.76 -2.07 1.38 -2.34 3.98 2.57 2.80 -2.38 12.18 4.39 5.37 -3.42
Endosome 3.50 13.58 2.68 0.36 -3.54 -0.90 1.56 2.41 2.62 0.13 1.63 17.25 4.36 2.47 -5.34
Golgi 2.81 16.92 2.10 0.82 -2.25 2.95 9.75 5.10 2.49 -1.34 3.89 18.21 5.52 2.53 -3.32
Lipid Particles 9.15 18.94 19.09 6.13 1.03 5.70 11.69 13.21 8.22 2.71 10.64 23.04 23.06 10.15 -0.45
Mitochondria 1.18 5.51 -0.36 -1.24 -3.06 -1.88 1.50 -3.02 -1.86 -3.51 -0.36 5.54 -2.73 -2.21 -4.46
Mitotic Spindle -5.75 -35.75 -10.30 -3.86 8.36 -6.99 -0.94 -15.41 -7.99 -3.21 -10.18 -40.18 -20.54 -8.80 10.48
None 3.04 6.32 4.41 1.52 -1.17 1.02 1.47 4.86 3.41 0.67 2.62 7.25 6.98 3.75 -0.77
Nuclear Periphery 0.65 3.27 -0.65 -0.94 -1.55 -0.70 -1.48 -4.56 -4.08 -1.24 0.85 2.28 -3.49 -3.48 -4.37
Nuclear Periphery Foci 1.21 20.96 23.61 11.05 5.98 6.03 1.55 18.16 11.90 2.70 5.79 25.74 28.77 16.09 4.03
Nucleolus 4.42 12.90 7.43 2.47 -1.92 2.53 3.38 10.99 8.00 1.71 4.67 15.62 14.69 8.11 -0.12
Nucleus -3.17 -0.78 -3.70 -1.26 -3.31 -1.63 -2.47 -2.56 -1.18 2.04 -3.66 -0.87 -4.63 -1.66 -3.61
Peroxisomes 6.36 20.48 15.48 5.09 -4.55 5.89 0.74 13.57 7.64 1.90 9.46 24.57 21.41 9.21 -4.12
Vacuole -4.20 0.31 -4.10 -3.65 -4.13 -3.50 -2.57 -6.29 -5.43 0.95 -4.70 -1.61 -7.39 -6.48 -7.08
Vacuole Periphery -1.22 1.04 -2.32 -2.17 -2.40 -2.04 -2.83 -3.24 -2.18 -2.78 -2.08 0.57 -3.86 -2.87 -3.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Microtubule plus end-tracking protein; together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally; homolog of human end binding protein 1 (EB1)
Localization
Cell Percentages spindle pole (27%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bim1

Bim1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bim1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available