Standard name
Human Ortholog
Description Transcriptional activator of genes regulated by nitrogen catabolite repression; localization and activity regulated by quality of nitrogen source and Ure2p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.08 0.09 0.06
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.13 0.06 0.12 0 0 0 0 0 0
Cytoplasm 0.68 0.87 0.54 0.12 0.14 0.22 0.18 0.15 0.15 – 0.13 0.22 0.99 0.99 0.98 0.85 0.92 0.91 0.62 0.76 0.44 0.47 0.18 0.18
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.07 0 0.05 0.06 0.06 0.06
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.13 0.14 0.14 0.51 – 0.47 0.26 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0.32 0.8 0.63 0.52 0.59 0.55 0.46 – 0.41 0.42 0 0 0 0 0 0 0.14 0.1 0.27 0.1 0.29 0.35
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0.06
Vac/Vac Membrane 0.32 0.12 0.2 0.09 0.27 0.22 0.15 0.17 0.09 – 0.13 0.15 0 0 0 0.11 0 0 0.05 0 0.08 0.12 0.2 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 3 0 3 0 2 1 0 – 0 1 0 0 0 0 0 0 0 2 1 1 0 1
Bud 0 0 1 0 2 1 6 6 6 – 10 8 1 1 1 0 0 0 7 8 7 6 17 10
Bud Neck 0 0 1 0 0 1 2 4 0 – 3 2 0 0 0 0 0 0 2 3 5 1 3 5
Bud Site 0 0 0 0 0 1 1 3 5 – 4 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 2 0 0 0 0 0 0 – 1 1 3 4 4 13 6 10 0 0 0 0 0 0
Cytoplasm 184 595 197 35 48 63 74 47 45 – 44 84 189 257 301 83 97 75 199 562 202 43 32 31
Endoplasmic Reticulum 2 6 7 0 2 1 2 0 0 – 1 1 2 2 1 3 6 5 1 1 1 1 2 1
Endosome 7 9 4 4 7 5 5 10 2 – 7 14 0 0 0 1 0 0 22 24 21 5 10 10
Golgi 0 0 0 1 0 0 0 0 0 – 0 0 0 0 0 1 0 0 1 1 0 0 1 0
Mitochondria 1 0 1 2 4 39 60 44 154 – 161 100 0 0 1 1 3 1 2 4 7 0 1 0
Nucleus 12 15 118 224 222 152 248 173 139 – 140 161 0 1 3 2 1 1 44 71 124 9 54 61
Nuclear Periphery 2 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 2 3 2 0 1 0
Nucleolus 4 0 0 2 0 1 1 3 2 – 2 3 0 0 0 0 0 0 3 5 12 1 10 12
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 2 3 2 4 2 6 0 – 3 10 0 0 0 0 0 0 13 9 29 5 7 10
Vac/Vac Membrane 87 81 73 25 97 65 64 54 26 – 43 57 0 0 3 11 4 3 17 31 35 10 36 26
Unique Cell Count 269 681 368 281 355 292 417 312 301 339 385 191 259 308 98 105 82 322 736 459 92 185 176
Labelled Cell Count 299 708 409 296 387 333 467 351 379 419 444 195 265 314 115 117 95 322 736 459 92 185 176


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.2 9.1 7.8 7.2 7.2 5.7 5.6 5.9 4.7 – 4.7 5.2 8.6 8.3 8.7 11.6 11.5 12.3 7.2 7.4 7.7
Std Deviation (1e-4) 1.4 1.3 0.8 1.2 1.1 1.1 1.0 1.2 0.8 – 0.8 0.8 1.2 0.9 1.2 1.9 2.2 1.6 1.0 1.3 1.4
Intensity Change (Log2) – – – -0.12 -0.12 -0.44 -0.47 -0.39 -0.74 – -0.73 -0.57 0.14 0.1 0.16 0.58 0.57 0.66 -0.12 -0.07 -0.02

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm -10.8 -11.4 -8.3 -10.5 -10.4 -10.3 – -11.4 -9.0 11.0 12.6 13.0 5.6 7.2 6.4
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 1.0 0 0 1.9 0 – 0 2.3 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 7.0 7.4 7.2 0 – 0 10.3 0 0 0 0 0 0
Nucleus 12.0 8.2 5.2 7.7 6.1 3.7 – 2.5 2.8 -8.8 -10.0 -10.5 -6.0 -6.5 -5.7
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 2.2 0 0 0 0 0 0
Vacuole -3.9 2.4 0.8 -1.7 -0.8 -4.1 – -2.6 -1.8 -6.6 -7.6 -7.7 -2.0 -3.9 -3.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.3041 6.14 4.72 4.9723 4.0892 5.1192 6.3304 7.7256 7.1643 6.9 7.0827 7.1773 0.1922 -0.0642 0.132 -0.0397 0.0853 0.1006
Actin 0.0039 0.0003 0.0043 0.0249 0.0015 0.0007 0.0116 0.0008 0.0015 0.0326 0.0092 0.002 0.0205 0.0002 0.0133 0.0002 0.0043 0.0044
Bud 0.0005 0.0002 0.0005 0.0007 0.0002 0.0001 0.0046 0.0006 0.0004 0.0026 0.0048 0.0003 0.0003 0.0001 0.0003 0.0001 0.0002 0.0001
Bud Neck 0.0007 0.0001 0.0006 0.0012 0.0004 0.0009 0.0034 0.0002 0.0002 0.0063 0.0079 0.0009 0.0083 0.0004 0.0013 0.0015 0.0013 0.0047
Bud Periphery 0.0004 0.0001 0.0003 0.0003 0.0001 0.0001 0.0009 0.0002 0.0001 0.0023 0.0026 0.0001 0.0006 0 0.0012 0.0001 0.0006 0.0003
Bud Site 0.0016 0.0005 0.0015 0.0006 0.0003 0.0001 0.0015 0.005 0.0004 0.0036 0.0061 0.0002 0.0033 0.0006 0.0007 0.0007 0.0005 0.0003
Cell Periphery 0.0004 0.0001 0.0001 0.0001 0 0 0.0003 0.0001 0 0.0003 0.0001 0 0.0004 0 0.0004 0.0001 0.0001 0.0001
Cytoplasm 0.8918 0.9706 0.9272 0.8806 0.9187 0.9577 0.8984 0.9734 0.9764 0.896 0.8899 0.9512 0.0219 0.06 0.0166 0.0144 0.0258 0.0085
Cytoplasmic Foci 0.0174 0.0056 0.0139 0.0115 0.0068 0.0074 0.0092 0.0043 0.0031 0.0096 0.0175 0.0077 0.0129 0.0012 0.0018 0.0018 0.0048 0.0023
Eisosomes 0.0001 0 0 0.0002 0 0 0.0001 0 0 0.0003 0 0 0.0003 0 0.0001 0 0.0001 0.0002
Endoplasmic Reticulum 0.0083 0.0023 0.0054 0.002 0.0043 0.0041 0.0076 0.0025 0.0011 0.0046 0.003 0.0047 0.0028 0.0015 0.001 0.0002 0.0016 0.0013
Endosome 0.0283 0.0073 0.017 0.0191 0.0452 0.0147 0.0218 0.0024 0.0035 0.0153 0.0207 0.0123 0.0149 0.0016 0.0023 0.0007 0.0096 0.0052
Golgi 0.0061 0.0008 0.0031 0.0054 0.0031 0.002 0.0034 0.0004 0.0003 0.0022 0.0039 0.0009 0.004 0 0.0012 0.0002 0.006 0.0013
Lipid Particles 0.0019 0.0002 0.0009 0.0077 0.0027 0.001 0.0011 0.0001 0.0001 0.0017 0.0003 0.0003 0.0121 0.0001 0.0011 0.0047 0.0058 0.0045
Mitochondria 0.0017 0.001 0.0016 0.0018 0.0014 0.0008 0.0037 0.0001 0.0027 0.0027 0.0022 0.0006 0.002 0.0003 0.0038 0.0006 0.0052 0.0031
None 0.0191 0.0061 0.0121 0.0246 0.0018 0.0052 0.0099 0.0053 0.0034 0.0044 0.0071 0.0036 0.1126 0.1083 0.0482 0.054 0.1172 0.0331
Nuclear Periphery 0.0044 0.0004 0.0017 0.0017 0.0058 0.0007 0.0051 0.0006 0.0005 0.0023 0.0026 0.0024 0.0196 0.0092 0.0133 0.0037 0.0323 0.0137
Nucleolus 0.0004 0 0.0001 0.0002 0.0001 0 0.0004 0 0 0.001 0.0003 0.0003 0.0105 0.0099 0.014 0.0271 0.01 0.0129
Nucleus 0.0032 0.0023 0.0029 0.0017 0.0018 0.0018 0.0098 0.0025 0.0027 0.0046 0.0066 0.0062 0.6603 0.7633 0.8256 0.876 0.7019 0.8382
Peroxisomes 0.0024 0.0001 0.0015 0.0038 0.0006 0.0001 0.0009 0.0001 0.0014 0.0019 0.0015 0.0002 0.0102 0 0.0032 0.0004 0.0032 0.0018
Punctate Nuclear 0.0012 0.0002 0.0013 0.0026 0.0018 0.0002 0.0021 0.0004 0.0002 0.0024 0.0036 0.0039 0.0795 0.0416 0.048 0.0128 0.0675 0.0624
Vacuole 0.0052 0.0015 0.0034 0.0074 0.0024 0.0018 0.0031 0.001 0.0016 0.0024 0.009 0.0016 0.002 0.0014 0.0019 0.0007 0.0013 0.0008
Vacuole Periphery 0.001 0.0003 0.0006 0.0018 0.001 0.0006 0.001 0.0001 0.0002 0.0009 0.0013 0.0004 0.0008 0.0002 0.0007 0.0001 0.0009 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.5598 7.1965 6.0077 13.5836 6.5235 10.5603 13.3022 13.0451 10.9752 14.7124
Translational Efficiency 0.8041 1.1787 1.4897 0.5974 1.5579 1.1406 0.6947 0.8385 1.1163 0.9473

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1501 1103 1249 1357 1495 851 1402 2926 2996 1954 2651 4283

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 721.78 948.22 1111.36 1024.95 910.63 977.45 926.78 1104.67 816.02 960.95 1013.74 1079.41
Standard Deviation 100.67 191.09 161.61 135.29 122.88 142.23 136.65 151.25 146.72 172.14 175.13 151.01
Intensity Change Log 2 — 0.393663 0.622695 0.505922 — 0.102158 0.025362 0.278679 — 0.238357 0.320250 0.383593

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000178 0.000352 0.000450 0.003225 0.000209 0.000434 0.000325 0.000297 0.000193 0.000388 0.000384 0.001225
Bud Neck 0.005466 0.001760 0.003166 0.007926 0.004313 0.003577 0.004099 0.013432 0.004891 0.002551 0.003660 0.011688
Bud Site 0.003425 0.005224 0.009647 0.053186 0.002645 0.010680 0.007142 0.019409 0.003036 0.007600 0.008323 0.030111
Cell Periphery 0.000153 0.000104 0.000110 0.000151 0.000105 0.000107 0.000182 0.000051 0.000129 0.000105 0.000148 0.000083
Cytoplasm 0.448683 0.742052 0.539672 0.556451 0.510982 0.671409 0.457515 0.736020 0.479770 0.711286 0.496222 0.679127
Cytoplasmic Foci 0.054177 0.047483 0.006204 0.026938 0.043634 0.090407 0.008891 0.004295 0.048916 0.066177 0.007625 0.011469
Eisosomes 0.000042 0.000018 0.000013 0.000023 0.000027 0.000025 0.000045 0.000007 0.000034 0.000021 0.000030 0.000012
Endoplasmic Reticulum 0.001854 0.002116 0.002445 0.001383 0.003204 0.001802 0.002817 0.000212 0.002527 0.001980 0.002642 0.000583
Endosome 0.002655 0.005941 0.001705 0.013210 0.003633 0.009958 0.002369 0.001267 0.003143 0.007690 0.002056 0.005051
Golgi 0.000626 0.001864 0.000174 0.007063 0.000326 0.002414 0.000114 0.000519 0.000477 0.002104 0.000142 0.002592
Lipid Particles 0.003289 0.001518 0.000894 0.002019 0.002128 0.002594 0.001196 0.000235 0.002709 0.001987 0.001054 0.000800
Mitochondria 0.001134 0.001974 0.000634 0.006384 0.001051 0.001791 0.000653 0.002024 0.001093 0.001894 0.000644 0.003405
Mitotic Spindle 0.002107 0.011765 0.018108 0.110686 0.005619 0.023478 0.008968 0.042388 0.003860 0.016866 0.013275 0.064027
None 0.016319 0.009329 0.007220 0.005171 0.006745 0.006238 0.012280 0.007171 0.011541 0.007983 0.009896 0.006538
Nuclear Periphery 0.001057 0.000587 0.001560 0.001137 0.002258 0.000559 0.001646 0.000593 0.001656 0.000575 0.001605 0.000765
Nuclear Periphery Foci 0.002601 0.007519 0.003624 0.003540 0.003893 0.004643 0.002529 0.000335 0.003246 0.006267 0.003045 0.001351
Nucleolus 0.005338 0.001049 0.000256 0.000445 0.003108 0.004067 0.001670 0.000433 0.004225 0.002363 0.001004 0.000437
Nucleus 0.435980 0.111521 0.352304 0.094005 0.371805 0.111853 0.421165 0.128267 0.403956 0.111666 0.388721 0.117411
Peroxisomes 0.001180 0.000709 0.000109 0.003388 0.000539 0.003419 0.000237 0.001161 0.000860 0.001889 0.000176 0.001867
Vacuole 0.013422 0.046019 0.051495 0.097065 0.033388 0.048392 0.065757 0.040676 0.023385 0.047053 0.059037 0.058542
Vacuole Periphery 0.000317 0.001095 0.000210 0.006603 0.000389 0.002152 0.000401 0.001208 0.000353 0.001555 0.000311 0.002918

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.31 -8.65 -2.64 -2.02 -1.29 -4.72 -5.57 0.25 4.32 4.73 -6.92 -10.26 -2.51 -0.50 0.47
Bud Neck 4.30 1.29 1.04 -4.12 -0.19 0.89 0.27 -3.28 -3.67 -3.12 4.24 1.11 -2.27 -5.94 -3.31
Bud Site -3.06 -3.03 -7.24 -6.08 -4.05 -5.56 -3.05 -7.11 1.09 -2.53 -6.42 -4.22 -9.86 -3.57 -4.16
Cell Periphery 3.35 0.72 4.48 1.59 5.52 -0.55 -4.42 9.17 9.96 15.44 2.39 -2.03 10.11 9.74 16.92
Cytoplasm -24.70 0.26 -3.82 21.23 -4.16 -11.43 11.29 -14.88 0.83 -29.89 -25.54 8.33 -16.67 13.02 -26.86
Cytoplasmic Foci 2.36 18.01 14.16 12.96 -9.31 -8.53 15.92 16.77 18.15 2.75 -4.94 23.98 22.87 23.29 -4.11
Eisosomes 9.27 10.46 7.06 -2.24 -2.95 0.20 -6.10 12.18 9.97 15.53 7.33 1.75 14.99 7.14 13.04
Endoplasmic Reticulum -1.46 -4.75 3.14 5.27 10.13 3.66 -3.99 12.55 8.44 18.76 1.59 -6.26 12.28 10.99 22.11
Endosome -4.98 2.29 -0.91 3.19 -2.25 -5.39 4.72 9.71 9.02 7.94 -7.17 5.02 6.42 10.59 2.87
Golgi -1.72 2.07 -1.22 0.46 -2.34 -3.61 3.20 1.48 3.88 -1.54 -3.56 2.90 -0.29 3.29 -2.57
Lipid Particles 5.59 6.78 5.57 -0.01 -1.13 -0.43 3.59 7.31 3.03 11.55 2.54 7.58 9.99 3.68 6.74
Mitochondria -0.71 2.69 -1.29 -0.14 -1.89 -0.83 1.06 -1.58 0.35 -3.45 -1.07 2.37 -1.98 0.26 -3.43
Mitotic Spindle -4.51 -7.21 -11.00 -8.06 -6.64 -3.97 -2.52 -8.36 -0.88 -5.73 -5.65 -7.01 -14.27 -6.22 -8.16
None 4.12 7.25 6.72 1.84 -1.36 0.35 -2.10 -4.64 -3.10 -1.22 3.49 4.90 3.71 -1.08 -2.79
Nuclear Periphery 3.40 -10.48 -5.94 -10.22 5.05 10.73 -3.38 5.51 -10.49 12.49 10.09 -9.27 1.04 -13.22 13.53
Nuclear Periphery Foci -5.09 -1.26 1.85 6.88 6.12 -0.77 2.55 7.17 8.27 10.02 -4.54 1.14 7.40 10.65 13.23
Nucleolus 6.43 7.94 7.82 3.90 -1.99 0.39 5.01 6.00 3.39 2.49 4.53 9.25 9.74 4.23 1.64
Nucleus 30.59 3.19 29.36 -3.55 27.70 22.84 -6.15 19.31 -9.68 28.68 37.83 -2.24 33.22 -11.80 38.49
Peroxisomes 2.69 7.40 1.73 -0.29 -2.54 -2.79 6.35 0.98 2.96 -1.00 -1.94 9.21 2.41 2.85 -2.19
Vacuole -12.47 -18.64 -32.97 -25.50 -17.57 -5.47 -15.47 -16.99 -7.41 4.40 -11.72 -23.73 -35.47 -22.21 -6.83
Vacuole Periphery -2.21 2.75 -2.44 -0.58 -2.71 -1.51 1.38 -0.14 1.46 -0.76 -2.21 2.22 -1.86 1.40 -2.45
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcriptional activator of genes regulated by nitrogen catabolite repression; localization and activity regulated by quality of nitrogen source and Ure2p
Localization
Cell Percentages cytoplasm (36%), nucleus (27%), mixed (36%)
Cell Cycle Regulation Yes
nucleus - MA (4.5e-05)
Subcompartmental Group N/A

Gln3

Gln3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gln3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available