Standard name
Human Ortholog
Description Putative ATPase of the AAA family; interacts with the Sin1p transcriptional repressor in the two-hybrid system
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.07 0 0.05 0 0 0 0 0 – 0 0 0.07 0 0 0.13 0.11 0.09 0.05 0.07 0.06 0.07 0.06 0.05
Bud 0 0 0 0 0 0 0 0 0 – 0.05 0 0.08 0.05 0.08 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.07 0 0 0 0 0 0.05 – 0 0.05 0 0 0 0 0 0 0.07 0.06 0.07 0.09 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 0 0 – 0 0 0 0.1 0.07 0.09 0.11 0.06 0 0 0 0 0 0
Cytoplasm 0.95 0.87 0.93 0.91 0.93 0.92 0.84 0.91 0.82 – 0.74 0.8 0.77 0.78 0.75 0.75 0.77 0.77 0.72 0.69 0.64 0.57 0.58 0.61
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 0 0 – 0 0 0 0 0 0.07 0.05 0.05 0 0 0 0 0.06 0.06
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0.05 0.06 0.1 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.1 0.15 0.06 0.19 – 0.39 0.24 0 0 0 0 0 0 0 0.06 0.13 0.13 0.1 0.1
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0.1 0.13 0.14 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0.06 0.05 0.07 0.08 0.07 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0.05 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 19 18 14 8 0 11 0 6 – 0 1 23 17 14 38 48 29 13 21 23 9 30 18
Bud 4 10 5 10 3 3 13 3 11 – 19 6 26 22 43 8 7 7 6 7 5 3 20 6
Bud Neck 2 0 28 10 10 2 19 12 17 – 5 17 0 0 1 0 4 1 20 17 28 11 19 14
Bud Site 0 1 3 0 3 1 4 0 1 – 1 4 5 0 2 1 0 3 – – – – – –
Cell Periphery 7 9 15 15 10 4 6 4 5 – 0 9 10 47 36 26 46 19 2 5 9 1 10 8
Cytoplasm 259 252 385 253 331 328 461 353 287 – 284 253 243 357 389 219 336 257 208 222 272 71 282 234
Endoplasmic Reticulum 0 15 3 1 3 1 5 0 3 – 0 1 1 1 3 20 20 16 2 6 4 2 31 21
Endosome 1 0 1 0 0 2 0 1 0 – 0 0 17 26 52 6 9 12 9 10 5 1 3 4
Golgi 0 1 0 0 0 0 0 0 0 – 0 0 0 0 0 4 4 2 2 1 1 0 2 1
Mitochondria 6 2 0 6 6 37 82 24 66 – 148 76 5 3 1 3 4 7 11 18 56 15 46 38
Nucleus 1 0 1 1 4 3 3 4 1 – 1 0 1 1 1 1 5 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 1 1 0 0 0 1
Nucleolus 0 0 0 0 0 1 0 0 0 – 0 0 0 0 1 0 1 0 0 0 0 0 0 2
Peroxisomes 0 1 0 0 0 0 1 0 0 – 0 0 32 61 73 1 3 3 0 0 0 0 2 2
SpindlePole 3 1 11 8 11 5 9 9 5 – 8 7 14 28 27 20 33 24 1 0 3 0 3 2
Vac/Vac Membrane 1 1 2 0 1 0 4 1 0 – 2 0 1 0 1 8 20 9 3 8 6 5 25 19
Unique Cell Count 274 289 413 279 357 357 551 389 350 383 318 316 460 518 291 437 332 289 324 426 126 485 385
Labelled Cell Count 292 312 472 318 390 387 618 411 402 468 374 378 563 644 355 540 389 289 324 426 126 485 385


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.2 5.8 5.5 5.2 5.4 4.2 4.2 4.6 3.5 – 3.3 3.8 5.5 5.8 5.8 8.5 8.8 7.8 5.4 5.4 5.8
Std Deviation (1e-4) 0.8 0.6 0.9 1.4 1.2 0.9 0.8 1.4 0.6 – 0.5 0.8 1.3 1.8 1.7 1.6 1.8 1.5 2.2 2.2 2.1
Intensity Change (Log2) – – – -0.1 -0.03 -0.4 -0.41 -0.27 -0.66 – -0.76 -0.54 -0.01 0.07 0.08 0.61 0.67 0.5 -0.05 -0.05 0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.4 -1.6 0 0 0 0 – 0 0 1.7 -0.5 -1.4 4.2 3.6 2.4
Bud 2.1 0 0 0 0 0 – 0 0 4.7 3.0 4.9 1.5 0.5 1.0
Bud Neck -1.8 -2.5 0 0 0 0 – 0 0 -4.7 -5.7 -5.7 -4.5 -4.5 -4.5
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 1.1 -0.6 0 0 0 0 – 0 0 -0.3 3.8 2.2 3.0 3.9 1.4
Cytoplasm -1.2 -0.3 -0.7 -4.5 -1.3 -4.8 – -7.3 -5.5 -6.3 -6.4 -7.3 -6.7 -6.6 -6.2
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 4.5 3.5 3.5
Endosome 0 0 0 0 0 0 – 0 0 4.4 4.6 6.4 0 0 3.5
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 6.6 7.7 7.9 0 0 0
SpindlePole 0.2 0.3 0 0 0 0 – 0 0 1.3 2.4 2.0 2.7 3.2 2.9
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 0 3.8 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.2366 2.9952 2.6172 2.2309 2.1602 2.7621 1.6018 1.4489 1.6444 1.5547 1.3994 1.5176 1.6025 1.5297 1.3218 1.6584 1.8312 1.5403
Actin 0.1114 0.0834 0.152 0.1312 0.1 0.0602 0.1109 0.059 0.1166 0.1205 0.2308 0.0751 0.0643 0.0069 0.0967 0.1014 0.1339 0.0366
Bud 0.0035 0.0073 0.0194 0.028 0.0243 0.0009 0.0138 0.0258 0.0472 0.0452 0.0407 0.0051 0.0226 0.0506 0.0689 0.0696 0.0214 0.0448
Bud Neck 0.0125 0.0062 0.0097 0.1306 0.0125 0.2068 0.0144 0.0062 0.0108 0.0454 0.0401 0.2334 0.011 0.0038 0.0047 0.0051 0.0623 0.1813
Bud Periphery 0.0146 0.0089 0.0897 0.1731 0.144 0.003 0.0265 0.0242 0.1288 0.1228 0.1118 0.0138 0.0348 0.0222 0.1384 0.1659 0.0408 0.0431
Bud Site 0.0494 0.1923 0.0345 0.0046 0.0084 0.0021 0.071 0.1406 0.0796 0.0154 0.0217 0.0104 0.0714 0.1886 0.0586 0.0206 0.0397 0.0098
Cell Periphery 0.0164 0.0113 0.0116 0.0125 0.0096 0.0041 0.0088 0.0032 0.0049 0.0042 0.0071 0.0033 0.0089 0.0047 0.0048 0.0103 0.0047 0.0036
Cytoplasm 0.4012 0.4174 0.4219 0.3495 0.3374 0.4415 0.4921 0.505 0.3965 0.3987 0.3461 0.5084 0.4228 0.4113 0.279 0.2668 0.3102 0.3972
Cytoplasmic Foci 0.0679 0.0354 0.0229 0.0343 0.0713 0.047 0.0602 0.0358 0.0332 0.0358 0.0262 0.0422 0.0721 0.0243 0.0323 0.0586 0.0372 0.0247
Eisosomes 0.0029 0.0016 0.0018 0.0011 0.0014 0.0009 0.0009 0.0004 0.001 0.0009 0.0013 0.0004 0.0012 0.0006 0.0005 0.0005 0.0014 0.0003
Endoplasmic Reticulum 0.0061 0.0037 0.0078 0.0044 0.0034 0.0029 0.0038 0.0028 0.004 0.0124 0.0026 0.0019 0.0102 0.0029 0.0027 0.0049 0.012 0.0022
Endosome 0.0121 0.0061 0.0093 0.0162 0.0118 0.0048 0.0237 0.0077 0.0203 0.0322 0.0135 0.0068 0.0189 0.0092 0.0099 0.0195 0.0206 0.0025
Golgi 0.0111 0.0082 0.0068 0.0103 0.0059 0.0032 0.0112 0.0052 0.0083 0.0088 0.0138 0.0047 0.0065 0.0017 0.006 0.0114 0.014 0.0017
Lipid Particles 0.008 0.0022 0.0036 0.0019 0.0261 0.0038 0.0085 0.0012 0.0032 0.0095 0.0045 0.0005 0.0096 0.0006 0.0037 0.0143 0.0044 0.0005
Mitochondria 0.0031 0.0007 0.0047 0.0148 0.0122 0.0018 0.011 0.0042 0.0079 0.0123 0.0054 0.0048 0.0191 0.0017 0.0064 0.0113 0.0132 0.002
None 0.2643 0.2035 0.1772 0.0807 0.2044 0.1997 0.102 0.1607 0.1155 0.0951 0.0644 0.0774 0.1889 0.2446 0.2313 0.1358 0.2273 0.2172
Nuclear Periphery 0.0008 0.0004 0.0017 0.0004 0.0008 0.0008 0.0046 0.0006 0.0023 0.0097 0.0022 0.0003 0.0046 0.0014 0.0036 0.0038 0.0181 0.0031
Nucleolus 0.0008 0.0004 0.0007 0.0002 0.0016 0.0002 0.0034 0.0014 0.0009 0.0011 0.0178 0.0003 0.0032 0.0025 0.003 0.0044 0.0041 0.0009
Nucleus 0.0011 0.0019 0.0014 0.0006 0.0011 0.0005 0.0052 0.0031 0.0034 0.0067 0.0141 0.0012 0.0044 0.0099 0.0195 0.0105 0.0065 0.0134
Peroxisomes 0.0071 0.0061 0.0112 0.0018 0.0113 0.0125 0.0184 0.0083 0.0062 0.0041 0.0279 0.0063 0.0113 0.0015 0.0135 0.0632 0.0118 0.0031
Punctate Nuclear 0.0025 0.0006 0.0075 0.0005 0.0094 0.0021 0.0025 0.0015 0.0043 0.006 0.0042 0.0024 0.0073 0.0077 0.0115 0.0103 0.0108 0.0087
Vacuole 0.0031 0.0022 0.0038 0.0026 0.0021 0.001 0.0059 0.0027 0.0041 0.0109 0.0033 0.0012 0.0056 0.0029 0.0041 0.0102 0.0043 0.0028
Vacuole Periphery 0.0004 0.0001 0.0007 0.0006 0.0009 0.0002 0.0013 0.0004 0.001 0.0023 0.0007 0.0002 0.0011 0.0004 0.0009 0.0017 0.0016 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.5293 5.1259 6.5206 8.7761 4.2483 6.959 8.5146 10.869 11.4775 9.4069
Translational Efficiency 1.6321 1.2111 1.2309 0.8979 1.542 1.314 1.1263 0.8768 0.8027 1.0284

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1483 2186 354 1557 1494 1890 1518 131 2977 4076 1872 1688

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 699.93 807.39 998.24 889.25 707.55 775.35 887.73 973.14 703.75 792.53 908.63 895.76
Standard Deviation 73.57 98.78 112.40 121.65 126.70 114.38 112.56 197.95 103.77 107.49 120.56 131.13
Intensity Change Log 2 — 0.206055 0.512176 0.345378 — 0.132016 0.327289 0.459815 — 0.169310 0.422192 0.404041

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001293 0.002537 0.018931 0.025668 0.000979 0.002009 0.004617 0.088597 0.001136 0.002292 0.007324 0.030552
Bud Neck 0.064381 0.045009 0.035402 0.035172 0.047192 0.065500 0.034410 0.018108 0.055755 0.054511 0.034598 0.033848
Bud Site 0.033434 0.062660 0.118495* 0.127364* 0.024516 0.061687 0.061375 0.260076* 0.028959 0.062209 0.072177 0.137663*
Cell Periphery 0.000348 0.000172 0.001037 0.000280 0.000402 0.000279 0.000335 0.000763 0.000375 0.000222 0.000468 0.000317
Cytoplasm 0.484671* 0.434482* 0.275942* 0.468707* 0.477317* 0.403768* 0.533531* 0.175393* 0.480980* 0.420240* 0.484821* 0.445944*
Cytoplasmic Foci 0.236037* 0.252193* 0.121830 0.062424 0.233486* 0.233093* 0.049650 0.113449 0.234757* 0.243336* 0.063300 0.066384
Eisosomes 0.000727 0.000310 0.000502 0.000193 0.000623 0.000426 0.000155 0.000248 0.000675 0.000363 0.000221 0.000197
Endoplasmic Reticulum 0.000872 0.000603 0.007390 0.000706 0.001503 0.000782 0.001730 0.000368 0.001189 0.000686 0.002801 0.000680
Endosome 0.023577 0.031068 0.013673 0.006366 0.020416 0.038427 0.005444 0.024039 0.021991 0.034481 0.007000 0.007738
Golgi 0.006566 0.018324 0.000674 0.003265 0.006575 0.015007 0.000285 0.004147 0.006571 0.016786 0.000358 0.003333
Lipid Particles 0.005593 0.002857 0.008285 0.001149 0.008770 0.005321 0.001973 0.001197 0.007188 0.004000 0.003167 0.001153
Mitochondria 0.003441 0.008283 0.000182 0.002340 0.003868 0.011223 0.000281 0.000380 0.003656 0.009646 0.000263 0.002188
Mitotic Spindle 0.000365 0.006905 0.002963 0.032215 0.003885 0.008745 0.005867 0.019880 0.002132 0.007758 0.005318 0.031258
None 0.001333 0.000790 0.000886 0.001479 0.015851 0.000952 0.003356 0.000359 0.008619 0.000865 0.002889 0.001392
Nuclear Periphery 0.000120 0.000082 0.000896 0.000331 0.000265 0.000123 0.000619 0.000039 0.000192 0.000101 0.000672 0.000308
Nuclear Periphery Foci 0.000275 0.000164 0.008923 0.000928 0.000913 0.000210 0.001560 0.000998 0.000595 0.000185 0.002952 0.000933
Nucleolus 0.000330 0.000360 0.000229 0.000239 0.001781 0.000590 0.000315 0.000126 0.001058 0.000466 0.000298 0.000230
Nucleus 0.030772 0.016736 0.094604 0.032360 0.060477 0.026963 0.104523 0.001606 0.045680 0.021479 0.102647 0.029973
Peroxisomes 0.011371 0.021010 0.027736 0.037663 0.009691 0.016636 0.007871 0.201628* 0.010528 0.018982 0.011628 0.050388
Vacuole 0.093015 0.092791 0.261211* 0.156369 0.080113 0.104451 0.181911 0.088230 0.086540 0.098198 0.196907 0.151081
Vacuole Periphery 0.001476 0.002664 0.000206 0.004782 0.001375 0.003807 0.000190 0.000371 0.001425 0.003194 0.000193 0.004440

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.46 -4.86 -7.14 -6.45 -0.53 -2.33 -3.52 -5.70 -5.62 -5.51 -4.11 -5.66 -8.97 -8.38 -6.60
Bud Neck 4.44 6.62 9.93 8.15 0.85 -4.12 5.71 4.57 7.65 1.05 0.43 9.58 11.11 13.22 1.02
Bud Site -9.15 -5.80 -10.02 -3.60 0.63 -10.99 -6.16 -9.55 -7.81 -8.45 -14.39 -7.51 -13.92 -6.30 -7.00
Cell Periphery 6.84 -7.01 5.34 -1.79 9.20 3.88 3.71 -0.84 -1.25 -1.24 7.51 -0.76 4.22 -0.59 4.80
Cytoplasm 5.55 15.59 2.66 -2.29 -13.17 7.88 1.06 12.59 9.43 11.94 9.34 6.33 4.92 -1.86 -0.94
Cytoplasmic Foci -2.24 17.30 33.12 38.64 6.67 0.10 34.51 9.56 9.59 -5.06 -1.62 43.50 41.37 45.49 -0.72
Eisosomes 5.00 3.50 7.15 6.19 5.05 2.75 8.15 5.01 2.74 -2.67 5.71 9.46 10.25 8.12 2.43
Endoplasmic Reticulum 1.48 -11.58 0.35 -1.71 11.94 2.86 -2.25 4.29 2.73 7.54 3.24 -8.42 2.43 -0.83 10.99
Endosome -4.25 7.56 16.06 19.93 7.58 -9.81 13.16 -0.07 2.50 -2.30 -9.89 17.74 16.09 24.69 1.30
Golgi -11.25 13.31 7.89 16.19 -2.80 -9.07 14.53 2.76 8.52 -2.80 -14.46 19.98 9.38 20.07 -3.84
Lipid Particles 5.76 -2.66 9.29 7.28 10.26 3.83 8.07 8.57 8.15 2.27 6.30 8.14 12.30 11.58 9.07
Mitochondria -4.70 4.23 2.46 8.93 -3.09 -5.57 4.07 4.03 10.97 -0.05 -7.23 5.80 3.53 12.32 -2.89
Mitotic Spindle -5.58 -3.21 -7.86 -5.11 -6.28 -2.45 -1.48 -2.35 -1.58 -1.96 -4.95 -3.24 -7.40 -5.13 -5.75
None 1.53 1.35 0.20 -0.97 -0.71 5.80 5.14 6.05 2.81 6.77 5.93 4.78 5.55 -0.76 2.67
Nuclear Periphery 0.90 -12.25 -6.37 -8.18 7.46 4.27 -10.26 6.00 3.13 15.09 3.58 -14.94 -5.51 -7.81 7.08
Nuclear Periphery Foci 4.35 -14.10 -5.63 -6.74 13.06 4.31 -4.89 -0.41 -1.64 1.29 4.92 -14.19 -2.19 -6.59 12.05
Nucleolus -0.86 1.90 2.08 1.87 0.12 3.11 3.74 4.23 4.06 2.57 2.99 3.70 4.19 4.07 2.11
Nucleus 10.25 -10.27 -7.94 -14.46 7.54 12.21 -13.76 24.40 16.68 30.98 15.61 -20.18 -0.26 -11.42 18.52
Peroxisomes -6.31 -1.63 -4.88 -0.68 -1.27 -5.18 3.14 -7.44 -7.11 -7.62 -8.26 2.05 -8.41 -5.28 -9.01
Vacuole -0.35 -16.57 -22.74 -22.73 4.87 -5.66 -24.80 -3.48 -2.33 4.72 -4.32 -29.19 -24.40 -22.42 2.50
Vacuole Periphery -5.40 8.23 -1.16 0.36 -2.87 -7.14 8.78 6.85 10.87 -2.00 -8.99 11.98 -1.12 1.36 -2.93
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative ATPase of the AAA family; interacts with the Sin1p transcriptional repressor in the two-hybrid system
Localization
Cell Percentages cytoplasm (81%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Sap1

Sap1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sap1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available