Standard name
Human Ortholog
Description Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain; BOI2 has a paralog, BOI1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.53 0.52 0.43 0.26 0.26 0.21 0.08 0.12 0.13 0.13 0.12 0.09 0.55 0.48 0.41 0.41 0.34 0.35 0.41 0.31 0.3 0.2 0.2 0.29
Bud 0.15 0.19 0.33 0.23 0.22 0.12 0.1 0.13 0.07 0.09 0.17 0.06 0.2 0.21 0.19 0.21 0.2 0.14 0.23 0.24 0.22 0.37 0.31 0.34
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.22 0.17 0.26 0.3 0.24
Bud Site 0.16 0.11 0 0 0.09 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.11 0.09 0.05 0.06 0.05 0.06 0.05 0.07 0.12 0.11 0.12 0.15 0.17 0.2 0.32 0.16 0.24 0.14 0.06 0 0 0 0 0
Cytoplasm 0.25 0.3 0.28 0.62 0.51 0.53 0.59 0.58 0.4 0.35 0.42 0.39 0.28 0.39 0.41 0.34 0.4 0.39 0.06 0.09 0.17 0.09 0.08 0.05
Endoplasmic Reticulum 0 0.13 0.05 0.09 0.07 0.09 0.07 0.05 0.06 0.07 0 0.08 0.07 0.11 0.07 0.06 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.05 0.28 0.14 0.11 0.24 0.26 0.31 0.51 0.55 0.46 0.42 0 0 0.05 0.05 0.05 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.1 0.1 0 0 0.05 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.06 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0.09 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 133 78 26 18 50 35 25 42 29 42 20 23 146 216 216 118 52 125 129 54 29 44 80 156
Bud 37 28 20 16 42 21 30 48 17 27 27 15 52 95 98 60 30 50 73 42 21 83 123 182
Bud Neck 2 0 0 0 1 1 0 0 0 1 1 0 0 0 0 0 3 0 49 37 16 58 120 131
Bud Site 41 17 1 1 17 8 9 8 10 10 3 12 11 11 6 4 2 5 – – – – – –
Cell Periphery 27 14 3 4 9 10 16 25 28 36 19 37 46 90 169 45 36 52 17 6 2 1 2 8
Cytoplasm 62 45 17 43 97 90 178 211 93 111 68 94 74 173 216 100 61 139 18 15 16 20 32 26
Endoplasmic Reticulum 10 19 3 6 14 15 20 19 14 22 7 19 18 48 35 16 11 10 9 2 0 1 12 11
Endosome 4 2 0 0 1 1 8 4 0 0 0 1 2 0 1 7 3 16 6 1 2 3 10 5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 3 12 2 0 0 0 3 0
Mitochondria 6 7 17 10 20 41 80 113 118 173 74 101 8 13 28 14 8 13 4 2 3 0 5 5
Nucleus 2 0 0 0 0 2 1 3 3 3 2 0 1 0 1 2 1 1 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 0 1 0 1 1 3 0 0 1 1 0 0 0 1 0 0 3 6
Nucleolus 1 0 0 0 0 1 4 2 4 1 1 1 0 1 0 1 1 1 0 0 0 0 0 0
Peroxisomes 24 15 0 0 9 1 7 2 3 4 2 3 22 8 3 11 2 7 0 0 0 0 0 1
SpindlePole 14 1 0 1 3 3 5 4 0 1 0 13 9 7 2 10 8 28 0 0 3 1 2 2
Vac/Vac Membrane 4 0 0 0 3 2 9 10 4 8 2 21 2 1 3 10 5 33 1 3 0 6 2 3
Unique Cell Count 250 151 61 69 189 169 303 365 231 315 161 243 264 448 523 290 152 361 315 173 98 223 404 545
Labelled Cell Count 367 226 87 99 266 231 392 492 323 440 227 343 391 663 779 407 226 492 315 173 98 223 404 545


Bud, Bud Neck, Cell Periphery, Cytoplasm, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.8 7.7 5.5 5.8 5.6 5.1 5.0 4.9 4.6 4.7 5.0 7.6 8.4 7.9 7.0 11.0 11.4 12.7 8.4 8.3 8.5
Std Deviation (1e-4) 1.6 1.5 0.7 0.7 1.1 0.8 1.1 0.9 0.8 0.9 1.3 6.2 1.6 1.6 1.5 2.7 2.8 3.3 1.2 1.5 1.3
Intensity Change (Log2) – – – 0.09 0.02 -0.1 -0.13 -0.16 -0.24 -0.22 -0.15 0.48 0.62 0.52 0.36 1.0 1.05 1.21 0.62 0.59 0.63

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.0 -2.4 -3.3 -7.1 -6.1 0 0 -5.0 -6.3 1.8 0.8 -0.2 -0.3 -1.2 -1.2
Bud -1.2 -1.7 -3.6 -4.7 -3.9 0 0 -2.6 -5.8 -2.2 -2.0 -2.6 -2.0 -2.0 -3.7
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 1.5 2.1 2.5 2.9 4.4 2.2 3.2 2.0
Cytoplasm 3.9 3.2 3.4 4.4 4.3 1.8 1.1 2.0 1.6 0 1.6 2.0 1.0 1.7 1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 1.4 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.9 -3.3 -0.6 -0.2 0.5 0 0 2.4 2.0 0 0 0 -5.8 -4.6 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5801 4.8652 4.0844 4.4785 3.1284 4.2669 4.5929 5.7732 5.6329 5.3741 5.6624 5.5062 2.4985 3.7343 3.4824 2.8827 2.5785 3.0987
Actin 0.2684 0.1103 0.2355 0.2733 0.3043 0.2195 0.21 0.0838 0.2019 0.2507 0.2979 0.158 0.1749 0.1648 0.1978 0.3976 0.2085 0.1928
Bud 0.0088 0.0378 0.1723 0.088 0.0155 0.009 0.0247 0.0155 0.2275 0.0888 0.0528 0.0268 0.0093 0.0234 0.1777 0.0586 0.0828 0.005
Bud Neck 0.0725 0.0064 0.0159 0.0042 0.0671 0.5149 0.1028 0.0116 0.0137 0.0071 0.0037 0.5784 0.0788 0.0089 0.0105 0.0012 0.1078 0.4478
Bud Periphery 0.0189 0.0527 0.3639 0.4732 0.1102 0.0379 0.0505 0.0156 0.3909 0.3331 0.4001 0.0897 0.0706 0.0365 0.3906 0.4575 0.3696 0.0152
Bud Site 0.1568 0.3234 0.0801 0.0176 0.0286 0.0124 0.1886 0.4556 0.0595 0.0175 0.0115 0.0254 0.1223 0.3263 0.0987 0.054 0.0336 0.0127
Cell Periphery 0.0184 0.025 0.009 0.0139 0.0044 0.0079 0.009 0.0121 0.0038 0.0066 0.0411 0.0095 0.0857 0.0116 0.0067 0.0056 0.0286 0.0048
Cytoplasm 0.2456 0.4172 0.0581 0.0376 0.0074 0.1679 0.2163 0.376 0.0673 0.0219 0.027 0.0603 0.3524 0.3713 0.088 0.0164 0.1315 0.2653
Cytoplasmic Foci 0.0385 0.0086 0.0094 0.0065 0.0162 0.008 0.04 0.0097 0.0057 0.03 0.0564 0.0168 0.0157 0.0038 0.002 0.0036 0.0259 0.0156
Eisosomes 0.002 0.0009 0.0004 0.0009 0.003 0.0006 0.002 0.0003 0.0005 0.0005 0.0004 0.0004 0.0064 0.0007 0.0007 0.0012 0.0007 0.0008
Endoplasmic Reticulum 0.021 0.002 0.0011 0.0012 0.008 0.0009 0.0095 0.0017 0.0004 0.0021 0.0005 0.0017 0.0075 0.0026 0.0017 0.0002 0.0014 0.0018
Endosome 0.0379 0.002 0.0073 0.0143 0.0633 0.002 0.0395 0.0015 0.0023 0.0686 0.0394 0.0059 0.015 0.0017 0.0009 0.0001 0.0016 0.0011
Golgi 0.0221 0.0038 0.0069 0.0214 0.0253 0.0039 0.0194 0.0024 0.003 0.0399 0.0416 0.0143 0.0075 0.0026 0.0007 0.0007 0.0027 0.0035
Lipid Particles 0.0106 0.0006 0.0056 0.0094 0.0316 0.0027 0.0085 0.0006 0.0013 0.0305 0.0042 0.0007 0.0084 0.0005 0.0001 0 0.0002 0.0025
Mitochondria 0.0082 0.0006 0.0174 0.0062 0.0674 0.005 0.0132 0.0004 0.0142 0.024 0.0053 0.0029 0.0058 0.0004 0.0006 0.0005 0.0009 0.0007
None 0.0097 0.0047 0.0016 0.0263 0.0191 0.0016 0.0287 0.0085 0.0009 0.001 0.0004 0.0006 0.0082 0.0418 0.0213 0.0008 0.0019 0.0172
Nuclear Periphery 0.0282 0.0004 0.0006 0.0011 0.0556 0.0007 0.0116 0.0003 0.0005 0.0078 0.0002 0.0002 0.0014 0.0004 0.0002 0.0001 0.0003 0.0001
Nucleolus 0.0008 0.0001 0.0016 0.0001 0.0164 0.0001 0.0008 0.0001 0.0002 0.0041 0.0001 0.0001 0.0004 0.0001 0 0 0.0001 0.0001
Nucleus 0.007 0.0007 0.0009 0.0004 0.0254 0.0004 0.0029 0.0008 0.0025 0.0297 0.0001 0.0006 0.0012 0.0007 0.0003 0.0001 0.0004 0.0003
Peroxisomes 0.0094 0.001 0.0065 0.002 0.074 0.003 0.0062 0.0009 0.0026 0.0199 0.0152 0.0062 0.0152 0.0002 0.0006 0.0007 0.0004 0.0118
Punctate Nuclear 0.0097 0.0003 0.0037 0.0007 0.044 0.0006 0.0117 0.0006 0.0002 0.0023 0.0006 0.0003 0.0043 0.0006 0.0001 0.0001 0.0004 0.0003
Vacuole 0.0031 0.0012 0.0018 0.0011 0.0066 0.0008 0.0027 0.0019 0.001 0.009 0.0011 0.0009 0.0085 0.001 0.0006 0.0007 0.0007 0.0004
Vacuole Periphery 0.0024 0.0001 0.0004 0.0006 0.0066 0.0002 0.0013 0.0001 0.0002 0.0049 0.0004 0.0002 0.0006 0.0001 0.0001 0.0001 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 27.5586 38.2169 27.1868 24.2987 26.1111 25.0715 36.8049 32.6541 25.6521 29.2655
Translational Efficiency 1.2231 1.1725 1.2404 1.0896 1.2927 1.1935 0.9993 0.9607 1.0136 0.9597

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1320 1083 161 901 1545 1045 1562 1317 2865 2128 1723 2218

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 807.15 976.63 1336.70 1047.51 802.19 892.93 1110.01 1102.45 804.48 935.53 1131.19 1080.13
Standard Deviation 108.56 142.28 130.92 160.25 133.20 123.69 148.50 161.60 122.49 139.88 161.08 163.30
Intensity Change Log 2 — 0.274975 0.727767 0.376055 — 0.154603 0.468557 0.458697 — 0.216230 0.604374 0.417841

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.061145 0.072086 0.246639 0.091528 0.165664 0.060209 0.060212 0.077602 0.117509 0.066254 0.077632 0.083259
Bud Neck 0.127609 0.070058 0.097939 0.022449 0.088552 0.125146 0.048665 0.028821 0.106547 0.097110 0.053269 0.026232
Bud Site 0.539466 0.616821 0.542024 0.645120 0.439782 0.556676 0.729001 0.702284 0.485709 0.587285 0.711529 0.679063
Cell Periphery 0.050859 0.008668 0.031329 0.017303 0.040953 0.016980 0.009823 0.030583 0.045517 0.012750 0.011833 0.025189
Cytoplasm 0.128101 0.151528 0.022161 0.134980 0.147187 0.140500 0.110939 0.122901 0.138393 0.146112 0.102643 0.127808
Cytoplasmic Foci 0.038312 0.032262 0.008238 0.013457 0.041509 0.032362 0.008238 0.003909 0.040036 0.032311 0.008238 0.007788
Eisosomes 0.007567 0.001017 0.011128 0.001827 0.009026 0.001917 0.000930 0.003801 0.008354 0.001459 0.001883 0.002999
Endoplasmic Reticulum 0.001418 0.002018 0.007175 0.000715 0.001933 0.001441 0.001071 0.001680 0.001696 0.001734 0.001642 0.001288
Endosome 0.006267 0.006715 0.002286 0.007394 0.009735 0.010369 0.002391 0.002315 0.008137 0.008510 0.002381 0.004379
Golgi 0.005577 0.005433 0.000559 0.005559 0.011559 0.005559 0.000743 0.001685 0.008803 0.005495 0.000726 0.003258
Lipid Particles 0.003231 0.000885 0.003113 0.002685 0.007158 0.001446 0.000409 0.000926 0.005348 0.001160 0.000661 0.001640
Mitochondria 0.004177 0.002834 0.000134 0.007114 0.008771 0.005444 0.001001 0.001522 0.006654 0.004116 0.000920 0.003794
Mitotic Spindle 0.000333 0.002601 0.000541 0.005753 0.000508 0.002173 0.001182 0.002506 0.000427 0.002391 0.001122 0.003825
None 0.000524 0.000220 0.000028 0.000168 0.000524 0.000277 0.000118 0.000061 0.000524 0.000248 0.000109 0.000105
Nuclear Periphery 0.000017 0.000024 0.000028 0.000034 0.000021 0.000021 0.000018 0.000062 0.000019 0.000022 0.000019 0.000051
Nuclear Periphery Foci 0.000190 0.000346 0.000787 0.000243 0.000281 0.000128 0.000303 0.000341 0.000239 0.000239 0.000348 0.000301
Nucleolus 0.000072 0.000071 0.000007 0.000214 0.000086 0.000061 0.000018 0.000006 0.000079 0.000066 0.000017 0.000091
Nucleus 0.004052 0.001785 0.001529 0.002417 0.002633 0.002847 0.003331 0.002240 0.003287 0.002307 0.003162 0.002312
Peroxisomes 0.009813 0.012632 0.003585 0.009820 0.016842 0.017201 0.003542 0.001488 0.013603 0.014876 0.003546 0.004873
Vacuole 0.010919 0.011124 0.020743 0.030744 0.006658 0.018132 0.017871 0.014624 0.008621 0.014565 0.018140 0.021172
Vacuole Periphery 0.000352 0.000870 0.000027 0.000477 0.000618 0.001112 0.000193 0.000641 0.000495 0.000989 0.000177 0.000575

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.64 -6.89 -3.01 -1.49 5.77 12.86 14.27 11.07 -2.15 -2.75 9.40 7.36 6.72 -2.39 -0.84
Bud Neck 8.23 2.44 18.01 10.38 4.96 -4.77 8.58 13.11 14.74 6.32 1.87 12.98 21.91 17.66 8.99
Bud Site -5.58 0.83 -4.11 0.84 -2.83 -8.41 -22.83 -19.81 -9.12 1.96 -10.32 -20.08 -17.00 -6.17 3.54
Cell Periphery 11.45 3.43 8.34 -2.68 2.28 6.98 10.48 2.96 -3.67 -6.81 13.15 14.01 7.44 -5.00 -5.82
Cytoplasm -2.67 7.20 -2.90 -0.37 -8.66 0.67 2.59 1.49 0.67 -1.04 -1.33 2.96 -0.86 0.46 -3.49
Cytoplasmic Foci 1.48 6.93 6.96 5.57 -1.02 2.23 11.20 13.57 9.57 4.60 2.67 13.90 14.80 11.29 1.10
Eisosomes 7.85 -1.11 6.77 -2.02 3.70 7.90 9.46 5.42 -2.93 -5.23 11.18 10.20 8.13 -3.80 -2.61
Endoplasmic Reticulum -0.84 -3.15 1.46 1.98 3.56 0.84 2.29 0.21 -0.54 -1.33 -0.10 -0.04 0.78 0.69 0.80
Endosome -0.40 2.44 -0.47 -0.16 -2.31 -0.40 6.11 6.34 5.69 0.27 -0.38 6.48 4.30 4.25 -1.85
Golgi 0.14 8.28 0.35 0.24 -3.17 4.23 9.78 7.87 3.50 -1.27 3.71 11.89 6.12 2.69 -3.17
Lipid Particles 2.68 -0.10 0.46 -1.49 0.41 4.33 5.28 4.56 0.69 -1.14 5.13 5.71 3.91 -0.85 -1.62
Mitochondria 1.12 4.37 -1.10 -1.81 -3.43 2.28 8.30 7.24 3.18 -0.88 2.69 8.26 3.09 0.59 -3.07
Mitotic Spindle -2.62 -1.21 -3.75 -1.81 -3.33 -2.60 -3.83 -2.11 -0.51 -1.07 -3.62 -4.40 -4.08 -1.53 -2.71
None 2.22 4.45 2.70 0.30 -2.59 1.43 2.99 3.09 1.55 0.56 2.50 4.51 4.15 1.49 -0.35
Nuclear Periphery -0.72 -2.30 -2.99 -1.83 0.61 0.03 -0.85 -1.63 -1.68 -1.42 -0.48 -2.17 -2.38 -2.15 -1.68
Nuclear Periphery Foci -1.01 -3.29 -1.54 0.12 2.84 2.20 -1.51 -0.90 -2.38 0.40 -0.05 -3.06 -1.58 -1.15 1.47
Nucleolus 0.00 4.32 -1.00 -0.99 -1.29 0.73 2.24 2.74 2.64 3.15 0.54 3.48 -0.47 -0.62 -1.16
Nucleus 2.82 0.81 0.04 -3.46 -0.87 -0.50 -2.41 -0.91 -0.35 1.22 1.62 -1.46 -0.53 -2.16 0.95
Peroxisomes -1.58 3.57 0.25 1.60 -2.91 -0.18 9.46 11.86 7.01 3.59 -0.84 10.00 8.55 7.02 -1.32
Vacuole -0.18 -3.44 -8.83 -8.77 -0.97 -5.59 -8.29 -6.96 -2.37 0.45 -4.54 -8.35 -11.05 -8.47 -2.76
Vacuole Periphery -1.56 6.81 -0.72 1.19 -3.16 -1.31 4.50 0.03 1.13 -1.67 -1.97 4.65 -0.31 1.53 -2.27
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain; BOI2 has a paralog, BOI1, that arose from the whole genome duplication
Localization
Cell Percentages actin (36%), cytoplasm (10%), mixed (23%)
Cell Cycle Regulation Yes
cytoplasm - T/G1 (0.00023)
actin - MA (9.2e-05)
Subcompartmental Group N/A

Boi2

Boi2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Boi2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available