Standard name
Human Ortholog
Description Coiled-coil 12S polarisome subunit; required for polarity establishment, apical bud growth, shmoo formation, filamentous differentiation; involved in Bni1p localization at sites of polarized growth, controlling polarized assembly of actin cables; role in apical growth affects diploid-specific bipolar bud site selection; retains Slt2p at bud tip to regulate ER inheritance; role in Ca2+ influx, cell fusion; S288C allele encoding Leu409 rather than Met linked with non-invasion
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.17 0.21 0.06 0.11 0.12 0 0.05 0 0 0.06 0 0 0.31 0.18 0.14 0.25 0.15 0.17 0.14 0.05 0.12 0 0 0
Bud 0.23 0.26 0.24 0.26 0.34 0.2 0.23 0.2 0.2 0.23 0.18 0.16 0.22 0.22 0.2 0.25 0.21 0.15 0.52 0.59 0.49 0.35 0.44 0.57
Bud Neck 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0.1 0 0.19 0.24 0.21 0.28 0.24 0.14
Bud Site 0.25 0.38 0.23 0.15 0.17 0.18 0.09 0.1 0.11 0.12 0.07 0.1 0.22 0.05 0 0.18 0.1 0.12 – – – – – –
Cell Periphery 0 0 0.05 0.12 0 0 0 0 0 0 0 0 0.06 0.08 0.06 0.05 0.05 0.11 0 0 0 0 0 0
Cytoplasm 0.16 0.19 0.12 0.2 0.24 0.26 0.2 0.24 0.22 0.19 0.21 0.2 0.25 0.45 0.52 0.13 0.18 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0.07 0.05 0.05 0.05 0 0.06 0 0 0 0 0 0 0.06 0.06 0.07 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0.27 0.33 0.05 0.16 0.08 0.22 0.36 0.26 0.42 0.42 0.56 0.55 0 0 0 0.1 0.1 0.12 0 0 0 0 0 0
Nucleus 0.06 0.12 0.06 0.07 0.11 0.05 0.06 0.09 0.09 0.05 0.06 0.06 0.09 0.08 0.06 0.06 0.07 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.09 0.07 0.07 0 0.1 0.09 0.12 0.1 0.1 0.09 0.07 0.07 0 0 0 0.12 0.09 0.06 0 0 0 0 0 0
Peroxisomes 0.09 0.07 0.2 0.16 0.11 0.15 0.09 0.1 0.08 0.07 0 0.06 0 0 0 0.1 0.1 0.12 0 0 0 0 0 0
SpindlePole 0.12 0.1 0.32 0.14 0.22 0.17 0.14 0.18 0.11 0.11 0.06 0.08 0.18 0.15 0.09 0.17 0.2 0.17 0.06 0 0.06 0.2 0.15 0.13
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0.06 0 0.05 0.05 0 0.06 0.07 0 0 0.14 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 34 9 12 18 31 14 22 12 7 28 12 10 95 57 58 39 17 11 34 3 27 3 6 6
Bud 47 11 47 43 90 63 107 93 66 99 60 63 67 71 81 38 24 10 127 48 110 27 171 213
Bud Neck 4 0 6 6 6 13 23 11 8 11 6 7 4 0 0 3 11 0 45 19 47 22 93 53
Bud Site 51 16 44 24 45 58 42 44 37 51 23 39 67 17 17 28 12 8 – – – – – –
Cell Periphery 6 0 10 19 3 4 11 9 6 16 8 8 19 26 25 8 6 7 3 0 1 0 0 0
Cytoplasm 33 8 23 33 63 84 92 111 73 81 69 80 74 145 213 20 21 11 3 3 3 1 5 11
Endoplasmic Reticulum 3 1 4 3 1 4 14 4 10 6 10 5 9 3 12 3 7 1 1 0 2 0 2 0
Endosome 5 1 14 8 12 17 12 27 12 9 9 4 8 11 23 9 8 3 1 0 3 1 8 4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 4 3 0 0 3 1 0 0
Mitochondria 55 14 10 26 20 71 165 120 138 183 183 218 4 1 2 16 12 8 6 1 7 0 1 3
Nucleus 12 5 12 11 30 16 28 42 30 22 20 24 27 25 23 9 8 3 0 0 0 1 2 2
Nuclear Periphery 0 0 0 0 0 1 2 3 0 1 6 8 0 0 0 0 0 1 0 0 0 0 0 0
Nucleolus 18 3 14 5 26 29 55 48 32 41 23 29 11 3 5 18 10 4 0 0 0 1 7 4
Peroxisomes 19 3 38 27 28 47 41 48 25 32 12 25 12 11 13 16 12 8 0 0 1 2 16 8
SpindlePole 25 4 63 23 57 56 63 82 36 50 21 30 53 50 35 27 23 11 13 2 13 16 58 49
Vac/Vac Membrane 3 0 8 2 3 5 18 22 18 16 15 19 8 20 28 6 4 9 2 0 0 0 6 6
Unique Cell Count 201 42 194 164 262 321 458 458 325 437 326 393 302 325 408 155 115 65 243 82 224 81 387 371
Labelled Cell Count 315 75 305 248 415 482 695 676 498 646 477 569 458 441 535 244 179 98 243 82 224 81 387 371


Ambiguous, Bud, Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 6.7 6.9 6.2 6.1 5.5 5.1 5.1 4.9 4.6 4.3 4.4 7.7 7.6 7.6 10.1 10.0 10.2 6.7 7.1 6.9
Std Deviation (1e-4) 2.2 1.8 2.1 1.9 2.2 2.1 1.8 1.7 1.5 1.3 1.2 1.2 2.1 2.0 1.9 2.9 3.4 2.9 1.5 2.1 1.9
Intensity Change (Log2) – – – -0.15 -0.16 -0.33 -0.44 -0.42 -0.5 -0.57 -0.68 -0.65 0.16 0.14 0.14 0.55 0.54 0.56 -0.04 0.05 0.01


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.6 2.0 -0.9 -0.7 -2.2 0 0 0 0 6.7 3.7 2.9 5.0 2.5 2.6
Bud 0.4 2.3 -1.2 -0.2 -1.1 0 0 0 0 -0.5 -0.6 -1.2 0.1 -0.7 -1.5
Bud Neck 0.3 -0.5 0.6 1.1 -0.5 0 0 0 0 0 0 0 0 2.4 0
Bud Site -1.9 -1.5 -1.3 -4.7 -4.5 0 0 0 0 -0.1 -6.0 -7.0 -1.1 -2.7 -1.8
Cell Periphery 2.2 -2.5 -2.6 -1.8 -2.2 0 0 0 0 0.5 1.2 0.5 0 0 0
Cytoplasm 2.1 3.3 3.9 2.5 3.6 3.0 2.1 2.7 2.5 3.5 7.7 9.5 0.3 1.6 1.0
Endoplasmic Reticulum 0 0 0 0.7 0 0 0 0 0 0.6 0 0.6 0 0 0
Endosome -0.9 -1.2 -0.9 -2.7 -0.6 0 0 0 0 -2.4 -2.0 -0.8 -0.5 -0.1 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.4 1.1 5.1 8.1 6.1 0 0 0 0 -2.5 0 0 1.8 1.7 0
Nucleus 0.2 1.9 -0.6 0 1.3 1.2 -0.6 0 0 1.1 0.6 -0.3 -0.1 0.3 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.8 1.0 0.7 1.8 1.3 0 0 0 0 -1.8 -3.9 -3.9 1.4 0.5 0
Peroxisomes -0.8 -2.7 -1.5 -3.8 -3.1 0 0 0 0 -5.6 -6.1 -6.8 -2.4 -2.1 -1.3
SpindlePole -4.1 -2.6 -3.9 -5.5 -4.1 0 0 0 0 -3.8 -4.6 -7.4 -3.2 -2.4 -2.4
Vacuole 0 0 0 -0.1 0.4 0.7 -0.3 0.3 0.4 -0.9 1.0 1.3 -0.1 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5621 2.6988 3.0664 3.4712 3.3964 3.6032 2.3357 0.9254 1.427 1.8153 1.6035 1.8444 2.0928 0.8062 0.9729 2.1288 1.6844 1.9454
Actin 0.0725 0.0089 0.0059 0.0338 0.055 0.0324 0.1048 0.0222 0.0133 0.0094 0.111 0.0358 0.0451 0.0187 0.0163 0.0161 0.0421 0.032
Bud 0.1034 0.1277 0.4065 0.1893 0.1613 0.0204 0.056 0.1301 0.4183 0.2149 0.113 0.0216 0.1398 0.1546 0.4595 0.1837 0.1852 0.0166
Bud Neck 0.1054 0.0067 0.0065 0.0516 0.0482 0.7826 0.0849 0.0067 0.0013 0.0136 0.0082 0.8148 0.0634 0.0093 0.0087 0.0156 0.0197 0.758
Bud Periphery 0.1307 0.1154 0.4525 0.5608 0.5292 0.0466 0.0984 0.0716 0.3626 0.5497 0.4799 0.0367 0.1319 0.0836 0.3624 0.45 0.4375 0.0276
Bud Site 0.3455 0.4876 0.0897 0.0381 0.0369 0.0213 0.2555 0.5517 0.1025 0.0427 0.0745 0.0236 0.3129 0.6158 0.0762 0.0559 0.0215 0.0169
Cell Periphery 0.0307 0.0065 0.0018 0.0049 0.0073 0.0057 0.0117 0.005 0.0021 0.0039 0.0026 0.0032 0.0128 0.0032 0.0025 0.005 0.0076 0.0028
Cytoplasm 0.0874 0.0296 0.0085 0.0453 0.0614 0.0173 0.1038 0.078 0.0061 0.0116 0.014 0.0117 0.0818 0.0227 0.011 0.0774 0.0633 0.032
Cytoplasmic Foci 0.0705 0.0163 0.0041 0.0363 0.0197 0.0474 0.1246 0.0334 0.0177 0.0504 0.0306 0.0197 0.0536 0.0413 0.0221 0.0382 0.0776 0.0788
Eisosomes 0.0006 0.0005 0.0001 0.0001 0.0005 0.0001 0.0009 0.0002 0.0001 0.0001 0.0003 0.0001 0.0004 0.0005 0.0001 0.0003 0.0002 0.0003
Endoplasmic Reticulum 0.0034 0.0006 0.0009 0.0015 0.0015 0.0004 0.0064 0.0015 0.001 0.0024 0.0005 0.0004 0.0143 0.0002 0.0005 0.0025 0.0038 0.0017
Endosome 0.0042 0.0018 0.0015 0.0013 0.0025 0.0023 0.0162 0.0025 0.0102 0.0258 0.0067 0.0033 0.0201 0.0018 0.0012 0.0029 0.0452 0.0038
Golgi 0.0045 0.0007 0.0004 0.001 0.0012 0.0018 0.0105 0.0022 0.0055 0.0053 0.009 0.0029 0.0103 0.0007 0.0013 0.0011 0.0139 0.0036
Lipid Particles 0.0035 0.0071 0.0005 0.0007 0.0055 0.0026 0.0256 0.0025 0.0069 0.0182 0.0034 0.0013 0.0066 0.0083 0.002 0.0027 0.0202 0.0039
Mitochondria 0.0037 0.0014 0.0019 0.0014 0.004 0.001 0.0088 0.0051 0.0113 0.0047 0.1008 0.0059 0.0099 0.0016 0.0123 0.0085 0.0049 0.0017
None 0.0079 0.1381 0.0088 0.0095 0.0455 0.001 0.0046 0.0409 0.0186 0.0075 0.0288 0.0027 0.034 0.0175 0.0083 0.0844 0.0168 0.0032
Nuclear Periphery 0.0004 0.0004 0.0008 0.0008 0.0007 0.0001 0.0132 0.0005 0.001 0.001 0.0004 0.0017 0.0215 0.0001 0.0007 0.0025 0.0112 0.0006
Nucleolus 0.0014 0.0071 0.0012 0.0011 0.0082 0.0016 0.0056 0.0065 0.0014 0.0094 0.0013 0.0022 0.0029 0.0084 0.0033 0.0041 0.0013 0.0006
Nucleus 0.0011 0.0036 0.0011 0.0017 0.0019 0.0013 0.0167 0.0035 0.0013 0.0021 0.002 0.0015 0.0054 0.0026 0.0035 0.0062 0.0039 0.0007
Peroxisomes 0.0031 0.001 0.004 0.0023 0.0025 0.0066 0.0335 0.0054 0.0075 0.0075 0.0056 0.0042 0.0143 0.0023 0.0026 0.0041 0.0081 0.0117
Punctate Nuclear 0.0126 0.0277 0.0016 0.0124 0.0022 0.0028 0.0062 0.009 0.0024 0.0029 0.0036 0.0013 0.0061 0.0046 0.0026 0.0126 0.0093 0.0015
Vacuole 0.0071 0.0102 0.0014 0.0053 0.0041 0.0041 0.0107 0.0202 0.0073 0.015 0.0034 0.0047 0.0108 0.0021 0.0024 0.0175 0.0051 0.0015
Vacuole Periphery 0.0005 0.0011 0.0002 0.0009 0.0007 0.0005 0.0014 0.0011 0.0016 0.0018 0.0007 0.0005 0.0021 0.0001 0.0005 0.0089 0.0016 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.8409 15.6196 14.488 16.6003 24.3533 22.702 13.8188 10.6592 15.5792 23.3628
Translational Efficiency 1.3057 0.9884 0.9381 1.0257 0.8483 1.213 0.9702 1.426 0.9367 1.0505

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1364 569 228 859 1415 1033 241 1679 2779 1602 469 2538

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 788.57 854.34 1013.96 941.64 746.67 861.59 1076.03 1033.77 767.24 859.01 1045.86 1002.59
Standard Deviation 116.11 146.49 133.70 146.23 115.00 131.24 145.53 152.56 117.43 136.89 143.30 156.64
Intensity Change Log 2 — 0.115572 0.362690 0.255937 — 0.206531 0.527176 0.469373 — 0.160526 0.445032 0.363688

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.011450 0.005085 0.004181 0.009800 0.002681 0.004248 0.007487 0.013816 0.006985 0.004545 0.005880 0.012457
Bud Neck 0.151740 0.088602 0.114956 0.087926 0.144784 0.124492 0.122158 0.060847 0.148198 0.111745 0.118656 0.070012
Bud Site 0.665597* 0.685440* 0.677537* 0.697738* 0.639428* 0.736115* 0.666273* 0.648787* 0.652273* 0.718116* 0.671749* 0.665354*
Cell Periphery 0.012789 0.003075 0.001343 0.001253 0.009587 0.005776 0.001236 0.000930 0.011159 0.004816 0.001288 0.001039
Cytoplasm 0.087622 0.107620* 0.048645 0.115353* 0.122183* 0.071179 0.054628 0.214794* 0.105220* 0.084122 0.051720 0.181138*
Cytoplasmic Foci 0.025327 0.039890 0.026501 0.021708 0.027408 0.018687 0.020664 0.015294 0.026386 0.026218 0.023501 0.017465
Eisosomes 0.001043 0.000192 0.000206 0.000170 0.000260 0.000218 0.000189 0.000124 0.000644 0.000209 0.000197 0.000139
Endoplasmic Reticulum 0.001785 0.000686 0.003254 0.000770 0.002275 0.001127 0.002743 0.000172 0.002035 0.000971 0.002991 0.000375
Endosome 0.007525 0.013656 0.003892 0.007541 0.008925 0.007396 0.003659 0.001880 0.008238 0.009619 0.003772 0.003796
Golgi 0.006431 0.006744 0.000681 0.002995 0.003245 0.003270 0.000879 0.001302 0.004809 0.004504 0.000783 0.001875
Lipid Particles 0.001195 0.000488 0.001131 0.000464 0.001020 0.000336 0.000847 0.000170 0.001106 0.000390 0.000985 0.000270
Mitochondria 0.006918 0.006852 0.000668 0.001223 0.004492 0.004712 0.001144 0.001366 0.005683 0.005472 0.000913 0.001318
Mitotic Spindle 0.001434 0.003992 0.008726 0.004697 0.001013 0.002130 0.006816 0.007662 0.001220 0.002791 0.007745 0.006659
None 0.000506 0.000500 0.000119 0.000168 0.001412 0.000355 0.000217 0.000215 0.000967 0.000406 0.000169 0.000199
Nuclear Periphery 0.000017 0.000020 0.000164 0.000038 0.000028 0.000016 0.000184 0.000039 0.000023 0.000017 0.000174 0.000039
Nuclear Periphery Foci 0.000560 0.000276 0.001050 0.000480 0.000293 0.000216 0.001700 0.000123 0.000424 0.000237 0.001384 0.000244
Nucleolus 0.000515 0.000251 0.000690 0.000197 0.000661 0.000173 0.000262 0.000200 0.000590 0.000201 0.000470 0.000199
Nucleus 0.001770 0.003109 0.019327 0.003480 0.004753 0.002817 0.033390 0.002734 0.003289 0.002921 0.026553 0.002987
Peroxisomes 0.005796 0.009832 0.008595 0.007413 0.003038 0.005284 0.008036 0.007733 0.004392 0.006900 0.008308 0.007625
Vacuole 0.008886 0.021711 0.077813 0.035881 0.020781 0.010326 0.067261 0.020947 0.014943 0.014370 0.072391 0.026001
Vacuole Periphery 0.001094 0.001978 0.000523 0.000708 0.001730 0.001127 0.000227 0.000864 0.001418 0.001430 0.000371 0.000811

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.87 4.54 0.70 -1.94 -2.40 -1.59 -1.14 -6.59 -5.06 -1.62 2.50 0.71 -3.58 -5.29 -2.85
Bud Neck 6.87 4.40 8.77 0.62 1.36 2.38 2.76 13.74 9.72 4.16 5.75 4.97 16.90 8.47 4.52
Bud Site -1.23 3.10 -0.42 0.78 -3.21 -8.06 1.54 2.32 10.40 -0.49 -7.04 3.26 2.26 8.78 -2.15
Cell Periphery 7.30 9.06 9.20 3.93 -0.05 3.68 9.74 10.20 8.08 1.54 7.38 13.00 13.46 8.96 1.14
Cytoplasm -2.40 2.24 -4.93 -2.01 -5.68 7.00 5.06 -12.74 -19.60 -14.65 3.81 5.27 -14.73 -17.28 -16.18
Cytoplasmic Foci -3.27 -0.36 0.51 3.51 0.64 2.79 0.82 3.83 0.54 1.34 -0.03 0.30 3.49 2.89 1.65
Eisosomes 4.09 4.09 4.30 0.45 1.56 0.87 1.40 3.00 3.77 3.19 4.17 4.29 4.92 2.92 3.69
Endoplasmic Reticulum 2.33 -3.40 1.92 -0.35 4.80 1.55 -1.47 4.21 1.67 4.27 2.17 -3.41 4.73 1.53 6.64
Endosome -3.03 2.07 0.15 2.84 -1.53 0.99 2.78 6.35 4.87 1.82 -1.15 3.46 4.99 5.51 0.82
Golgi -0.17 7.22 3.13 2.21 -2.55 -0.04 3.78 3.90 3.52 -0.78 0.39 7.95 5.45 3.76 -2.54
Lipid Particles 2.45 -1.47 2.38 -0.16 4.05 2.09 -0.67 2.46 1.44 4.08 3.31 -1.49 3.69 0.83 6.05
Mitochondria 0.05 6.46 5.87 3.27 -1.69 -0.16 3.20 3.07 3.09 -0.18 0.19 6.70 6.05 4.47 -0.88
Mitotic Spindle -2.88 -2.39 -3.65 -0.90 1.13 -2.09 -3.19 -5.94 -4.81 -0.45 -3.31 -3.82 -6.76 -4.71 0.29
None 0.01 2.04 2.03 2.18 -0.18 3.51 3.92 4.04 1.10 0.19 3.03 4.41 4.44 2.24 -0.21
Nuclear Periphery -0.57 -6.20 -4.77 -4.41 5.58 1.55 -3.91 -2.33 -3.31 3.49 1.12 -6.59 -3.68 -4.32 5.85
Nuclear Periphery Foci 2.16 -3.30 0.08 -0.93 2.49 1.15 -1.92 2.49 1.40 2.09 2.60 -2.77 1.26 -0.44 3.05
Nucleolus 0.88 -0.39 1.09 0.60 1.52 1.17 0.93 1.10 -0.31 0.64 1.50 0.37 1.50 -0.03 1.60
Nucleus -2.02 -5.61 -4.09 -1.45 5.17 1.56 -5.23 0.21 -1.61 5.26 0.23 -7.56 -2.56 -2.12 7.32
Peroxisomes -2.24 -0.84 -0.86 1.17 0.15 -2.17 -1.58 -4.34 -1.72 -0.04 -2.66 -1.77 -3.41 -0.50 0.03
Vacuole -4.70 -8.10 -7.97 -4.89 5.36 4.75 -6.31 -4.16 -7.90 5.30 0.19 -10.24 -9.16 -8.96 7.78
Vacuole Periphery -2.31 2.13 1.75 3.26 -0.55 1.96 6.21 2.59 0.96 -1.84 -0.10 5.76 2.75 2.53 -1.64
Standard name
Human Ortholog
Description Coiled-coil 12S polarisome subunit; required for polarity establishment, apical bud growth, shmoo formation, filamentous differentiation; involved in Bni1p localization at sites of polarized growth, controlling polarized assembly of actin cables; role in apical growth affects diploid-specific bipolar bud site selection; retains Slt2p at bud tip to regulate ER inheritance; role in Ca2+ influx, cell fusion; S288C allele encoding Leu409 rather than Met linked with non-invasion
Localization
Cell Percentages bud neck (21%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pea2

Pea2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pea2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available