Standard name
Human Ortholog
Description GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; SPI1 has a paralog, SED1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.99 0.97 0.96 0.95 – 0.8 0.78 0.8 0.77 0.78 0.97 0.98 0.99 0.84 0.88 0.88 0.87 0.7 0.67 0.79 0.81 0.75
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.06 0 0.06 0 0.11 – 0.27 0.32 0.2 0.23 0.25 0 0 0 0 0 0 0 0.09 0.09 0 0.06 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0.05 0.06 0 0 0 0.16 0.1 0.11 0 0.1 0.12 0.07 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 – 0 0 1 0 1 0 0 0 0 0 0 1 0 2 1 3 7
Bud 0 0 1 5 5 3 – 12 16 17 8 15 1 0 2 0 0 0 0 0 0 0 8 16
Bud Neck 0 0 3 1 13 10 – 11 7 5 2 2 0 0 1 0 1 0 1 2 0 1 0 1
Bud Site 0 0 0 0 0 2 – 0 1 5 2 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 0 2 4 3 3 – 0 4 1 4 5 0 3 1 2 1 6 0 0 0 0 2 2
Cytoplasm 285 92 154 407 652 548 – 533 391 475 294 352 234 712 730 125 125 145 256 90 92 59 372 355
Endoplasmic Reticulum 5 2 0 0 3 0 – 2 2 5 14 8 3 6 1 5 9 10 0 2 1 0 2 2
Endosome 0 0 0 0 1 0 – 0 1 0 1 2 0 0 0 4 6 2 1 2 2 0 2 5
Golgi 0 0 0 1 0 0 – 0 0 0 0 0 0 1 1 1 0 0 0 1 0 0 1 2
Mitochondria 6 6 3 27 23 64 – 180 159 119 90 112 3 6 2 5 2 2 11 11 13 2 29 21
Nucleus 0 0 0 1 2 2 – 14 6 13 7 10 1 1 1 1 0 3 0 0 0 0 1 7
Nuclear Periphery 0 0 0 1 0 0 – 9 5 11 5 5 0 1 1 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 – 3 1 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 7 4 – 4 5 6 3 7 0 0 0 0 2 1 2 0 1 1 4 11
Vac/Vac Membrane 0 0 0 1 3 4 – 20 11 23 18 27 1 1 2 24 14 18 12 12 16 5 18 24
Unique Cell Count 291 95 155 421 676 574 666 500 591 384 450 240 724 736 149 142 164 294 128 139 75 458 472
Labelled Cell Count 298 100 164 449 713 640 788 609 682 449 547 244 732 742 167 160 187 294 128 139 75 458 472


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.7 4.7 3.2 2.9 3.3 2.8 – 3.3 2.9 3.6 3.8 4.0 4.0 4.3 4.2 6.2 6.2 6.4 3.8 4.0 4.5
Std Deviation (1e-4) 0.5 5.2 0.5 0.9 1.1 1.0 – 1.3 1.4 1.7 2.5 2.6 1.1 0.8 1.1 1.9 2.0 1.9 1.3 1.7 2.2
Intensity Change (Log2) – – – -0.17 0.03 -0.23 – 0.01 -0.14 0.15 0.24 0.31 0.32 0.4 0.37 0.93 0.94 0.97 0.25 0.32 0.48

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 5.2 4.0 4.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.6589 0.4068 0.0413 0.6153 0.1565 -0.0192 -0.5753 -0.6405 -0.632 -0.8071 -0.4824 -0.7485 0.34 1.5051 0.9293 1.1073 1.0298 0.8143
Actin 0.0625 0.0002 0.0096 0.0776 0.0463 0.0001 0.0334 0.0027 0.0113 0.0248 0.0115 0.0017 0.0002 0.0004 0.0004 0.0002 0.0005 0.0001
Bud 0.001 0.0005 0.0003 0.0037 0.0098 0.0001 0.0013 0.0045 0.0041 0.0011 0.0007 0.0001 0.0001 0.003 0.0015 0.0002 0.0001 0
Bud Neck 0.0018 0.0001 0.0004 0.0004 0.0005 0.0002 0.0027 0.0003 0.0028 0.0005 0.014 0.0007 0 0.0001 0.0001 0.0001 0.0002 0.0003
Bud Periphery 0.0016 0.0004 0.0003 0.0223 0.0264 0.0002 0.0022 0.0058 0.0039 0.0027 0.0021 0.0002 0.0001 0.003 0.003 0.0007 0.0001 0
Bud Site 0.011 0.0018 0.0023 0.0011 0.0038 0 0.0119 0.0107 0.0054 0.0017 0.0026 0.0005 0.0001 0.0037 0.001 0.0001 0.0001 0.0001
Cell Periphery 0.0004 0.0001 0.0001 0.0002 0.0003 0.0001 0.0009 0.0004 0.0004 0.0001 0.0003 0 0.0002 0.0004 0.0003 0.0002 0.0001 0.0001
Cytoplasm 0.0841 0.1643 0.1363 0.1406 0.1226 0.2371 0.1098 0.1926 0.1452 0.1477 0.1156 0.2059 0.1504 0.1918 0.1947 0.1421 0.2285 0.2369
Cytoplasmic Foci 0.0233 0.0057 0.0075 0.0289 0.0297 0.0086 0.0351 0.014 0.0125 0.0139 0.0127 0.0091 0.0091 0.0084 0.0096 0.0031 0.0039 0.0042
Eisosomes 0.0004 0 0.0002 0.0003 0.0002 0 0.0005 0.0001 0.0003 0.0002 0.0003 0.0001 0.0002 0.0002 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.003 0.0222 0.0182 0.0312 0.0013 0.0017 0.0062 0.0047 0.0082 0.0055 0.0016 0.0069 0.0276 0.0236 0.0226 0.0031 0.055 0.0304
Endosome 0.0178 0.0041 0.0078 0.0201 0.0212 0.0048 0.0326 0.002 0.0069 0.0067 0.0339 0.0084 0.0014 0.0028 0.0035 0.0056 0.0006 0.0026
Golgi 0.0115 0.0001 0.0044 0.0093 0.0057 0.0002 0.0071 0.0002 0.0041 0.0023 0.0273 0.0025 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001
Lipid Particles 0.0268 0.0004 0.0036 0.0149 0.024 0.0004 0.0124 0.0011 0.0041 0.0009 0.0306 0.0059 0.0007 0.0007 0.0005 0.0001 0.0001 0.0005
Mitochondria 0.0199 0.0002 0.0034 0.0043 0.0266 0.0006 0.0116 0.001 0.0174 0.0033 0.0254 0.0034 0.0002 0.0055 0.0005 0.0002 0.0002 0.0002
None 0.6764 0.7941 0.7914 0.5893 0.6231 0.7418 0.6901 0.7525 0.7578 0.78 0.7003 0.7384 0.8026 0.7437 0.7445 0.8293 0.708 0.7097
Nuclear Periphery 0.0118 0.001 0.0019 0.0291 0.001 0.0004 0.0059 0.0012 0.0015 0.0014 0.0038 0.0037 0.003 0.0023 0.0024 0.0005 0.0009 0.0008
Nucleolus 0.0006 0.0002 0.0001 0.0004 0.0009 0.0001 0.0026 0.0005 0.0008 0.0003 0.0014 0.0001 0.0002 0.0009 0.0003 0.0001 0 0
Nucleus 0.0073 0.0009 0.0006 0.0063 0.0013 0.0006 0.004 0.0016 0.0017 0.0013 0.0012 0.0008 0.001 0.0022 0.0023 0.0005 0.0007 0.0007
Peroxisomes 0.0325 0.0001 0.0009 0.0114 0.0149 0.0001 0.0106 0.0004 0.0063 0.0017 0.0049 0.0065 0.0001 0.0003 0.0001 0 0.0002 0
Punctate Nuclear 0.0042 0.0006 0.0006 0.0045 0.0012 0.0008 0.012 0.0017 0.0029 0.0021 0.0025 0.0013 0.0015 0.0024 0.0016 0.0001 0.0005 0.0002
Vacuole 0.0015 0.0027 0.0096 0.0026 0.0349 0.0017 0.005 0.0018 0.0018 0.0018 0.003 0.0028 0.001 0.0037 0.0102 0.0129 0.0002 0.0127
Vacuole Periphery 0.0008 0.0002 0.0006 0.0015 0.0041 0.0004 0.002 0.0003 0.0006 0.0004 0.0043 0.0008 0.0002 0.0006 0.0007 0.0006 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.4054 2.2067 3.2749 10.3123 6.4009 32.0723 2.2311 8.2823 9.8257 9.1865
Translational Efficiency 3.2378 1.3105 1.8513 0.7807 0.4359 1.9902 5.0072 1.5394 2.3004 0.9611

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1306 1554 503 816 1349 1407 1868 909 2655 2961 2371 1725

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 591.36 626.89 908.58 829.88 590.36 665.57 809.46 866.62 590.85 645.27 830.49 849.24
Standard Deviation 91.65 95.66 136.30 184.56 197.43 96.97 106.78 181.21 154.72 98.20 120.69 183.72
Intensity Change Log 2 — 0.084176 0.619577 0.488866 — 0.172995 0.455365 0.553805 — 0.129231 0.539875 0.521673

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000075 0.000232 0.000492 0.002892 0.000089 0.000371 0.000564 0.003170 0.000082 0.000298 0.000549 0.003038
Bud Neck 0.005631 0.039508 0.002949 0.010022 0.014115 0.055200 0.015669 0.011551 0.009942 0.046965 0.012971 0.010828
Bud Site 0.001517 0.012796 0.005228 0.051171 0.004852 0.015745 0.017516 0.048955 0.003211 0.014197 0.014909 0.050003
Cell Periphery 0.000226 0.000087 0.000315 0.004419 0.000259 0.000157 0.000162 0.001057 0.000243 0.000120 0.000195 0.002648
Cytoplasm 0.562887 0.449159 0.282249 0.442735 0.451496 0.377277 0.407321 0.468109 0.506289 0.415003 0.380787 0.456106
Cytoplasmic Foci 0.165099 0.225699 0.021934 0.030824 0.215787 0.256227 0.008276 0.037791 0.190853 0.240205 0.011173 0.034495
Eisosomes 0.000338 0.000108 0.000073 0.000329 0.000184 0.000204 0.000032 0.000133 0.000260 0.000154 0.000041 0.000225
Endoplasmic Reticulum 0.001015 0.000463 0.067886 0.014314 0.000514 0.000839 0.007168 0.009230 0.000760 0.000642 0.020049 0.011635
Endosome 0.004706 0.021891 0.006808 0.010451 0.009031 0.033329 0.002373 0.013871 0.006904 0.027326 0.003314 0.012253
Golgi 0.000998 0.003263 0.000136 0.011144 0.001190 0.006016 0.000382 0.010445 0.001095 0.004571 0.000330 0.010775
Lipid Particles 0.007815 0.007945 0.005421 0.008368 0.014315 0.009708 0.001153 0.007246 0.011117 0.008783 0.002058 0.007776
Mitochondria 0.003078 0.010301 0.000488 0.007051 0.005372 0.017014 0.001666 0.007800 0.004244 0.013491 0.001416 0.007446
Mitotic Spindle 0.000730 0.003075 0.000265 0.039874 0.000639 0.004989 0.016209 0.016543 0.000684 0.003984 0.012827 0.027580
None 0.023146 0.006123 0.002143 0.007282 0.008428 0.003437 0.003797 0.003344 0.015667 0.004846 0.003446 0.005207
Nuclear Periphery 0.000628 0.000546 0.016679 0.001398 0.001160 0.000400 0.005108 0.000909 0.000898 0.000476 0.007563 0.001140
Nuclear Periphery Foci 0.000906 0.000403 0.027275 0.003846 0.000317 0.000248 0.001517 0.003479 0.000607 0.000329 0.006981 0.003652
Nucleolus 0.001889 0.003673 0.000586 0.000307 0.002002 0.002838 0.000414 0.000255 0.001947 0.003276 0.000451 0.000280
Nucleus 0.194030 0.119741 0.466464 0.181674 0.220537 0.107592 0.454601 0.143414 0.207499 0.113968 0.457118 0.161513
Peroxisomes 0.003357 0.016609 0.000341 0.001767 0.005972 0.024769 0.002291 0.003214 0.004686 0.020487 0.001877 0.002529
Vacuole 0.021178 0.076501 0.092023 0.166369 0.043064 0.080738 0.053376 0.202481 0.032298 0.078514 0.061575 0.185398
Vacuole Periphery 0.000752 0.001876 0.000246 0.003765 0.000678 0.002903 0.000405 0.007006 0.000714 0.002364 0.000371 0.005473

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.58 -8.25 -4.62 -4.14 -3.15 -6.59 -2.19 -3.77 -3.08 -2.77 -8.58 -3.05 -5.76 -4.96 -4.00
Bud Neck -14.01 4.22 -2.51 12.99 -6.30 -13.03 0.90 3.87 15.26 2.62 -18.69 -0.42 2.40 19.88 2.16
Bud Site -9.65 -1.79 -7.50 -4.15 -5.63 -5.64 -4.12 -6.46 -3.52 -4.00 -9.70 -5.61 -9.83 -5.46 -5.93
Cell Periphery 5.78 -2.60 -1.83 -2.00 -1.72 1.40 1.51 -1.57 -2.37 -2.42 3.16 1.49 -2.14 -2.46 -2.30
Cytoplasm 11.66 23.26 16.25 6.42 -6.49 7.10 10.42 5.15 -0.91 -2.94 12.66 23.12 14.79 3.97 -4.69
Cytoplasmic Foci -8.44 27.56 27.66 36.83 -0.35 -5.00 38.81 33.53 37.60 -11.56 -9.13 48.58 43.04 52.41 -11.44
Eisosomes 3.00 3.34 1.75 -1.36 -1.87 -1.16 17.69 5.71 5.66 -5.33 2.79 5.59 2.69 0.57 -3.61
Endoplasmic Reticulum 2.80 -8.37 -4.20 -4.57 7.16 -1.27 -6.60 -3.13 -2.88 0.52 0.76 -9.93 -5.16 -5.26 5.35
Endosome -13.28 -2.88 -0.33 11.36 1.61 -11.73 8.53 1.61 11.91 -4.20 -16.96 7.65 1.09 16.08 -4.00
Golgi -7.24 6.43 -1.85 -0.41 -2.43 -6.61 4.88 -2.12 1.26 -2.87 -9.00 6.86 -2.81 0.52 -3.71
Lipid Particles -0.15 3.39 1.68 1.84 -0.67 3.21 10.64 6.24 3.96 -3.28 2.75 12.62 6.05 4.18 -4.35
Mitochondria -4.95 2.88 0.19 5.35 -2.97 -5.98 4.12 1.24 6.46 -1.65 -7.68 4.54 1.09 8.21 -2.58
Mitotic Spindle -2.77 0.66 -6.73 -6.04 -6.90 -3.67 -6.71 -5.89 -3.63 -0.28 -4.62 -6.57 -8.86 -7.07 -3.56
None 6.08 7.80 6.60 1.33 -2.42 3.47 3.35 3.84 0.65 1.99 6.90 8.08 7.63 1.63 -0.32
Nuclear Periphery 0.48 -6.04 -7.96 -9.96 5.22 2.21 -4.59 -1.35 -12.37 4.42 2.19 -7.83 -5.26 -14.70 6.44
Nuclear Periphery Foci 2.60 -7.72 -5.56 -7.26 6.84 1.21 -5.53 -5.74 -5.96 -3.00 2.78 -8.20 -7.93 -9.16 4.12
Nucleolus -4.64 5.85 7.35 9.65 3.92 -1.46 6.17 6.63 5.64 1.81 -4.12 8.74 9.73 10.62 2.96
Nucleus 11.64 -20.58 -1.20 -9.75 18.15 16.44 -31.32 4.79 -8.34 31.83 19.92 -40.05 2.63 -12.65 37.34
Peroxisomes -8.66 3.64 2.96 12.10 -3.11 -10.36 5.18 4.24 12.73 -0.06 -13.40 5.20 5.09 17.21 -0.03
Vacuole -17.85 -14.05 -27.44 -21.12 -16.05 -9.99 -10.95 -26.60 -22.14 -21.13 -18.94 -17.94 -38.18 -30.64 -27.45
Vacuole Periphery -3.61 1.94 -1.25 1.11 -2.74 -5.15 4.03 -2.30 0.06 -2.75 -6.39 3.08 -2.61 0.37 -3.54
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; SPI1 has a paralog, SED1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (24%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Spi1

Spi1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Spi1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available