ORF
Human Ortholog
Description Protein with 2-aminoadipate transaminase activity; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.97 0.94 0.92 0.85 0.74 0.69 0.66 0.6 0.62 0.62 1.0 0.99 0.98 0.91 0.93 0.94 0.93 0.94 0.9 0.95 0.94 0.93
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0 0.16 0.25 0.22 0.28 0.36 0.44 0.38 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.06 0.08 0.08 0.1 0.15 0.16 0.2 0.12 0.09 0 0 0 0.12 0.06 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Bud 1 0 0 0 2 0 2 4 7 11 0 4 0 0 0 0 0 0 3 0 5 0 1 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 5 1 1 2 6 10 2 5 0 4 0 0 0 7 1 6 0 0 0 0 0 0
Cytoplasm 291 114 299 222 326 327 402 401 319 340 130 213 20 189 239 277 258 187 279 117 284 62 213 172
Endoplasmic Reticulum 2 0 2 0 1 0 3 3 9 4 1 7 0 0 2 8 10 6 1 0 3 0 0 0
Endosome 0 0 0 0 0 0 0 1 2 0 0 1 0 0 0 0 2 0 1 0 3 0 0 0
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 0 0 0
Mitochondria 6 1 3 13 14 63 138 127 136 202 93 131 0 0 0 1 2 0 1 0 2 0 1 0
Nucleus 2 1 1 2 3 3 16 18 16 13 4 11 0 1 4 11 7 2 1 2 0 2 1 3
Nuclear Periphery 0 0 0 0 0 1 0 1 1 2 1 4 0 0 0 0 0 0 0 0 1 0 2 0
Nucleolus 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Vac/Vac Membrane 1 3 5 13 27 29 53 86 77 115 26 30 0 2 0 35 16 12 4 0 4 0 2 1
Unique Cell Count 296 118 307 236 354 386 545 584 486 565 211 345 20 190 243 304 276 198 300 125 315 66 227 185
Labelled Cell Count 303 119 316 251 374 425 620 651 570 693 255 405 20 192 245 339 297 214 300 125 315 66 227 185


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.8 8.0 7.4 7.0 7.2 6.4 6.3 6.2 5.8 5.6 5.3 5.5 7.0 8.4 8.1 14.0 13.3 13.7 7.1 8.2 8.7
Std Deviation (1e-4) 1.3 1.6 1.3 1.8 1.7 1.2 1.3 1.3 1.2 1.2 1.3 1.2 0.9 1.3 1.1 2.7 2.9 3.1 0.8 1.4 1.6
Intensity Change (Log2) – – – -0.1 -0.06 -0.22 -0.25 -0.27 -0.35 -0.41 -0.48 -0.44 -0.09 0.18 0.12 0.91 0.84 0.88 -0.06 0.14 0.23


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0.1 0 0 0 0 0 0 0 0.6 0 0
Cytoplasm -1.9 -3.0 -5.6 -8.7 -9.9 -10.5 -11.9 -10.6 -11.1 0.7 1.7 0.8 -3.3 -2.3 -1.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 2.5 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.1 2.4 6.8 9.2 8.3 9.7 11.6 12.4 11.7 0 0 0 0 0 0
Nucleus 0 0 0 2.6 2.7 2.8 0 0 2.7 0 0 0 2.9 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.5 3.6 3.6 4.5 6.1 6.4 7.7 5.0 4.0 0 0 0 4.9 2.7 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.6935 3.2694 3.2958 2.5324 2.3646 3.0306 2.2458 2.2398 1.8574 1.9744 1.5912 2.0078 1.2089 2.0489 1.1524 1.2097 1.4162 1.2415
Actin 0.008 0.0005 0.0017 0.0004 0.0003 0.0022 0.0471 0.001 0.0159 0.0065 0.0052 0.0076 0.0004 0.0002 0.0006 0.0002 0.0005 0.0004
Bud 0.0002 0.0042 0.0002 0.0002 0.0001 0.0004 0.0033 0.0008 0.0011 0.0009 0.0009 0.0004 0.0001 0.0001 0.0003 0.0003 0.0002 0.0001
Bud Neck 0.0014 0.0004 0.0013 0.0004 0.0003 0.0009 0.0147 0.0003 0.0009 0.0013 0.0006 0.0052 0.0001 0.0001 0.0014 0.0005 0.0005 0.0044
Bud Periphery 0.0003 0.0023 0.0001 0.0002 0.0001 0.0005 0.0047 0.0004 0.0011 0.0006 0.0007 0.0005 0.0001 0 0.0001 0.0002 0.0001 0
Bud Site 0.0009 0.0107 0.0022 0.0001 0.0001 0.0002 0.0089 0.0065 0.0037 0.0056 0.0006 0.0004 0.0001 0.0005 0.0011 0.0001 0.0001 0.0001
Cell Periphery 0.0001 0.0003 0.0001 0 0 0 0.0004 0.0001 0.0002 0.0002 0.0001 0.0001 0 0 0 0 0 0
Cytoplasm 0.6392 0.7646 0.7403 0.7305 0.8085 0.759 0.5479 0.8676 0.8039 0.8259 0.8505 0.8644 0.8111 0.8914 0.8671 0.8702 0.8732 0.8458
Cytoplasmic Foci 0.0096 0.0066 0.0051 0.0096 0.0077 0.008 0.0354 0.0092 0.017 0.0283 0.0154 0.0165 0.005 0.0036 0.005 0.0079 0.0226 0.0072
Eisosomes 0.0003 0 0.0001 0 0 0 0.0003 0 0.0002 0.0001 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0036 0.0018 0.002 0.0015 0.0024 0.0019 0.0092 0.0023 0.0057 0.0042 0.0033 0.0046 0.0043 0.0029 0.0022 0.0021 0.0032 0.002
Endosome 0.0029 0.0017 0.0017 0.0032 0.0036 0.0047 0.0554 0.0031 0.0127 0.0238 0.0116 0.0186 0.0056 0.0021 0.0022 0.0072 0.0091 0.0064
Golgi 0.0011 0.0002 0.0003 0.0002 0.0002 0.0002 0.0155 0.0005 0.0025 0.0078 0.003 0.0056 0.0012 0.0001 0.0001 0.0001 0.0003 0.0007
Lipid Particles 0.0018 0.0001 0.0005 0.0001 0.0001 0.0002 0.0105 0.0015 0.0023 0.0082 0.015 0.004 0.0003 0 0.0001 0 0.0002 0.0034
Mitochondria 0.0005 0.0002 0.0004 0.0003 0.0003 0.0002 0.0158 0.0006 0.0034 0.0044 0.0023 0.002 0.0044 0.0002 0.0002 0.0004 0.0003 0.0008
None 0.3185 0.1997 0.2354 0.2435 0.1678 0.2131 0.1444 0.0917 0.1003 0.0549 0.0427 0.0448 0.1466 0.0895 0.1014 0.0781 0.0622 0.1058
Nuclear Periphery 0.0012 0.0006 0.0009 0.0007 0.0013 0.0009 0.0315 0.0014 0.008 0.0028 0.0112 0.0039 0.003 0.0017 0.0015 0.0027 0.0023 0.0017
Nucleolus 0.0007 0.0001 0.0002 0.0001 0 0.0001 0.0015 0.0001 0.0006 0.0004 0.0005 0.0001 0.0002 0 0.0001 0.0001 0.0001 0.001
Nucleus 0.0041 0.0039 0.0046 0.0067 0.005 0.0034 0.0206 0.0044 0.0098 0.0093 0.0186 0.0128 0.0128 0.0057 0.0141 0.0262 0.0158 0.016
Peroxisomes 0.0029 0.0001 0.0012 0.0002 0.0001 0.0002 0.0089 0.005 0.0021 0.0051 0.01 0.0029 0.0003 0 0.0001 0.0001 0.0002 0.0006
Punctate Nuclear 0.0019 0.001 0.0009 0.001 0.0011 0.0031 0.0104 0.0022 0.0054 0.0066 0.0038 0.0027 0.003 0.0006 0.0013 0.001 0.0068 0.0026
Vacuole 0.0007 0.001 0.0006 0.0007 0.0007 0.0007 0.0082 0.0013 0.0024 0.0024 0.003 0.0022 0.0011 0.0009 0.0009 0.002 0.002 0.0009
Vacuole Periphery 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0054 0.0002 0.0008 0.0007 0.0011 0.0007 0.0003 0.0001 0.0002 0.0005 0.0004 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 49.2887 37.7667 24.7275 35.9834 58.5348 37.2565 35.378 31.5844 39.964 62.0977
Translational Efficiency 0.4464 0.5098 0.4622 0.4871 0.4933 0.5914 0.5057 0.724 0.454 0.4483

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
68 413 1415 107 1662 1761 138 95 1730 2174 1553 202

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 985.41 882.83 1040.08 1099.77 871.42 866.27 1129.10 1072.10 875.90 869.42 1047.99 1086.76
Standard Deviation 187.50 137.33 181.50 139.27 118.16 130.71 170.31 188.19 123.63 132.15 182.31 164.68
Intensity Change Log 2 — -0.158588 0.077898 0.158406 — -0.008551 0.373733 0.298999 — -0.086229 0.224308 0.226096

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003869 0.000459 0.000410 0.000490 0.000138 0.000511 0.000300 0.000519 0.000285 0.000501 0.000400 0.000504
Bud Neck 0.004317 0.006399 0.002838 0.001916 0.002459 0.004317 0.002106 0.003212 0.002532 0.004712 0.002773 0.002526
Bud Site 0.038546 0.018410 0.008450 0.005149 0.003762 0.008984 0.003723 0.005081 0.005129 0.010774 0.008030 0.005117
Cell Periphery 0.001056 0.000113 0.000110 0.000178 0.000096 0.000064 0.000339 0.000181 0.000134 0.000073 0.000131 0.000179
Cytoplasm 0.468608* 0.663596* 0.517487* 0.443344* 0.693051* 0.696941* 0.320265* 0.582534* 0.684229* 0.690606* 0.499962* 0.508805*
Cytoplasmic Foci 0.153655 0.115937 0.005536 0.019022 0.095113 0.089760 0.044344 0.013526 0.097414 0.094733 0.008984 0.016438
Eisosomes 0.000099 0.000043 0.000016 0.000068 0.000035 0.000030 0.000154 0.000035 0.000037 0.000033 0.000028 0.000052
Endoplasmic Reticulum 0.035920 0.001105 0.002307 0.004476 0.003010 0.000599 0.004358 0.001909 0.004304 0.000695 0.002489 0.003268
Endosome 0.010343 0.012524 0.001041 0.003283 0.004357 0.006810 0.009850 0.006649 0.004592 0.007896 0.001824 0.004866
Golgi 0.005950 0.001706 0.000094 0.000093 0.000783 0.002990 0.000131 0.000676 0.000987 0.002746 0.000097 0.000367
Lipid Particles 0.030150 0.002486 0.000602 0.002400 0.001883 0.001260 0.004835 0.002108 0.002994 0.001493 0.000978 0.002263
Mitochondria 0.008064 0.001328 0.000493 0.000156 0.001194 0.003671 0.000198 0.005937 0.001464 0.003226 0.000467 0.002875
Mitotic Spindle 0.004964 0.002821 0.005563 0.002644 0.002116 0.016143 0.000496 0.004846 0.002228 0.013612 0.005113 0.003680
None 0.003981 0.003877 0.006175 0.006124 0.003249 0.003140 0.009828 0.018480 0.003278 0.003280 0.006499 0.011935
Nuclear Periphery 0.001166 0.000205 0.001030 0.001117 0.000349 0.000275 0.001576 0.002390 0.000381 0.000262 0.001079 0.001716
Nuclear Periphery Foci 0.014540 0.001909 0.001992 0.005958 0.001610 0.001275 0.005662 0.004595 0.002118 0.001395 0.002318 0.005317
Nucleolus 0.007141 0.000595 0.000160 0.000115 0.000331 0.000752 0.001182 0.000233 0.000598 0.000722 0.000251 0.000170
Nucleus 0.119010 0.064166 0.401711* 0.160512* 0.133980* 0.092433 0.311378* 0.101589 0.133392* 0.087063 0.393684* 0.132801*
Peroxisomes 0.011323 0.003853 0.000142 0.000210 0.000697 0.002640 0.000642 0.000353 0.001115 0.002870 0.000186 0.000277
Vacuole 0.068715 0.097644 0.043735 0.342622* 0.051275 0.066470 0.278361* 0.226512* 0.051960 0.072392 0.064584 0.288016*
Vacuole Periphery 0.008581 0.000824 0.000111 0.000123 0.000512 0.000934 0.000274 0.018635 0.000829 0.000913 0.000126 0.008829

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 4.03 3.91 3.62 -2.70 -1.70 -1.67 -5.34 -4.97 -0.02 -1.11 -1.10 -2.54 -4.51 -0.93 -1.09
Bud Neck -0.69 1.66 1.93 2.56 0.45 -3.76 0.69 -0.84 2.74 -1.36 -4.51 -1.81 -1.27 3.29 0.75
Bud Site 1.65 2.55 2.57 3.61 0.11 -4.67 -0.97 -3.23 -0.04 -2.56 -4.68 -1.49 -2.49 1.91 -0.56
Cell Periphery 4.57 4.51 4.12 -3.39 -3.12 5.52 -8.40 -3.80 -6.07 5.25 5.66 -0.50 -2.51 -7.20 -2.48
Cytoplasm -5.42 -0.11 4.07 13.75 7.14 0.40 21.01 11.43 11.28 -2.04 0.16 28.56 19.00 18.95 6.27
Cytoplasmic Foci 1.56 7.78 7.31 13.52 -4.28 1.20 12.07 21.35 20.35 4.07 0.61 28.01 24.35 25.49 -4.40
Eisosomes 3.49 4.86 1.31 -5.13 -9.65 1.87 -10.71 -4.77 -5.62 7.75 1.90 1.15 -7.73 -8.98 -8.43
Endoplasmic Reticulum 4.07 3.84 3.52 -6.17 -3.56 3.56 -3.10 0.95 -5.84 5.65 4.81 1.25 0.18 -8.03 -1.75
Endosome -0.69 6.13 4.61 4.49 -5.28 -3.60 -4.61 3.06 5.25 5.90 -4.73 8.40 3.86 7.05 -2.47
Golgi 2.78 4.10 4.08 2.57 -1.21 -3.49 3.45 3.01 4.68 -0.70 -3.24 4.59 4.27 5.20 -1.42
Lipid Particles 2.53 2.68 2.48 -0.60 -6.44 2.31 -5.99 -0.49 -2.67 5.54 2.76 3.57 0.74 -3.42 -6.13
Mitochondria 2.15 2.41 2.51 1.58 5.65 -2.37 1.85 0.46 2.54 -0.87 -1.90 1.77 1.55 3.40 0.08
Mitotic Spindle 1.22 0.53 -0.79 -1.53 -1.16 -5.50 1.31 -1.21 0.98 -1.43 -5.26 -2.29 -1.95 0.13 -1.38
None 0.12 -1.57 1.29 1.30 4.06 0.36 -0.90 -2.03 -2.21 -0.03 0.20 -4.18 -0.82 -0.99 1.77
Nuclear Periphery 2.90 -0.75 -2.43 -8.83 -3.21 0.96 -10.22 -5.37 -5.43 1.79 1.84 -21.23 -9.38 -9.64 -1.94
Nuclear Periphery Foci 5.03 4.87 2.84 -4.77 -4.42 1.21 -6.94 -4.39 -4.76 2.40 2.73 -2.39 -5.45 -6.57 -4.59
Nucleolus 1.92 2.05 2.06 3.22 1.34 -1.56 -2.60 4.83 2.22 3.54 -0.51 2.48 3.18 2.58 3.64
Nucleus 3.06 -14.94 -2.09 -6.22 12.95 8.96 -7.42 0.16 -2.49 5.97 10.66 -38.04 -1.93 -5.71 18.91
Peroxisomes 1.57 2.34 2.30 4.62 -1.08 -4.62 0.22 3.95 6.05 2.29 -4.18 4.02 3.39 6.99 -0.77
Vacuole -1.07 0.46 -11.68 -12.69 -14.11 -6.18 -12.91 -12.07 -11.38 -2.14 -7.92 -10.92 -19.20 -17.83 -16.35
Vacuole Periphery 1.76 1.92 1.92 6.41 0.11 -1.93 3.62 -0.79 -0.61 -0.92 -0.32 3.87 -0.29 -0.22 -0.97
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Protein with 2-aminoadipate transaminase activity; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene
Localization
Cell Percentages cytoplasm (98%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YER152C

YER152C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yer152c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available