Standard name
Human Ortholog
Description Transcriptional activator of nitrogen catabolite repression genes; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p; different translational starts produce two major and two minor isoforms that are differentially regulated and localized
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.8 0.92 0.55 0.1 0.07 0.06 0.08 0.06 0.08 0.08 0.08 0.07 0.98 0.99 0.99 0.7 0.91 0.93 0.45 0.73 0.31 0.63 0.79 0.68
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.12 0 0.07 0.05 0.14 0.27 0.34 0.26 0.27 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0.05 0.74 0.7 0.53 0.56 0.62 0.49 0.52 0.47 0.55 0 0 0 0 0 0 0.32 0.15 0.37 0.19 0.07 0.05
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.19 0.09 0.15 0.13 0.12 0.13 0.18 0.18 0.16 0 0 0 0 0 0 0 0 0.05 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.3 0.1 0.47 0 0.16 0.29 0.23 0.15 0.19 0.14 0.15 0.17 0 0 0 0.35 0.1 0 0.06 0.05 0.14 0.07 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud 0 0 0 0 0 0 2 1 3 3 0 1 0 0 0 1 0 0 5 6 2 0 1 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 0 0 1
Bud Site 0 0 0 0 0 0 1 1 4 4 1 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 3 3 0 2 2 2 0 0 0 0 0 0
Cytoplasm 80 368 74 4 8 11 22 17 17 20 18 19 124 319 263 154 129 79 55 302 56 63 178 142
Endoplasmic Reticulum 0 4 0 0 0 0 1 0 0 0 0 0 1 1 0 5 3 4 0 0 3 0 3 3
Endosome 0 0 0 0 1 1 6 2 0 0 1 0 0 0 0 3 1 0 1 2 5 1 3 10
Golgi 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 9 5 3 0 0 0 0 0 0
Mitochondria 0 1 1 5 1 12 15 42 55 90 61 72 0 0 1 2 1 2 0 0 2 0 0 0
Nucleus 2 5 7 31 80 93 160 179 99 139 112 149 0 0 2 5 0 0 40 61 67 19 15 10
Nuclear Periphery 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 2 2 3 2 5 3
Nucleolus 1 1 2 8 10 26 38 34 26 47 42 44 0 1 0 0 2 0 5 4 8 2 0 3
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 2 4 1 0 6 8
Vac/Vac Membrane 30 42 63 0 18 51 66 44 38 36 36 45 0 3 0 78 14 2 7 22 25 6 5 10
Unique Cell Count 100 401 134 42 114 176 284 291 201 266 239 271 126 322 265 220 142 85 124 415 184 102 225 210
Labelled Cell Count 113 425 151 48 118 194 311 321 242 341 272 336 128 327 266 260 158 92 124 415 184 102 225 210


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 19.5 21.7 20.2 16.5 15.8 12.4 11.0 10.8 10.0 9.5 9.6 9.7 18.0 17.0 15.7 22.8 29.7 30.7 17.4 18.3 20.1
Std Deviation (1e-4) 2.8 4.0 4.1 5.6 4.2 2.3 2.4 2.3 2.1 2.2 2.1 2.5 3.3 2.7 2.4 6.7 8.2 9.2 3.8 3.0 4.1
Intensity Change (Log2) – – – -0.29 -0.36 -0.71 -0.88 -0.91 -1.02 -1.09 -1.07 -1.05 -0.17 -0.25 -0.36 0.17 0.55 0.6 -0.22 -0.14 -0.01


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -5.2 -8.0 -9.6 -10.8 -11.5 -9.4 -10.6 -10.3 -10.9 8.2 12.4 11.5 2.8 6.7 5.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.6 2.3 4.3 6.4 7.5 6.2 6.4 0 0 0 0 0 0
Nucleus 9.4 10.7 8.9 10.0 10.9 8.5 9.2 8.3 9.7 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 2.7 4.0 3.9 3.5 3.7 4.7 4.6 4.4 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -5.5 -5.2 -3.3 -4.9 -7.0 -5.5 -7.3 -6.7 -6.5 -8.8 -12.7 -12.2 -2.2 -6.9 -7.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.8892 4.7486 4.3075 4.2221 3.3899 4.389 5.0964 5.7427 4.808 4.2875 3.9535 5.2951 7.2372 7.1987 6.557 6.5659 5.7943 6.8135
Actin 0.013 0.0006 0.0017 0.0412 0.0019 0.0004 0.08 0.0006 0.0076 0.0119 0.0031 0.0069 0.0502 0.0044 0.0213 0.0014 0.0263 0.0015
Bud 0.0004 0.0003 0.0002 0.0003 0.0002 0.0003 0.0004 0.0002 0.0003 0.0002 0.0001 0.0003 0.0019 0.0006 0.0008 0.0004 0.0009 0.0003
Bud Neck 0.0003 0.0003 0.0005 0.0012 0.0007 0.0082 0.0031 0.0002 0.0004 0.0006 0.0004 0.0016 0.0018 0.0007 0.0059 0.0014 0.001 0.0025
Bud Periphery 0.0006 0.0001 0.0001 0.0002 0.0001 0.0001 0.0005 0.0001 0.0002 0.0002 0.0001 0.0004 0.0019 0.0003 0.0011 0.0001 0.0015 0.0002
Bud Site 0.0008 0.0013 0.0004 0.0007 0.0003 0.0004 0.002 0.0006 0.0008 0.0013 0.0003 0.0005 0.0037 0.003 0.0029 0.0005 0.0012 0.0002
Cell Periphery 0.0001 0.0005 0.0001 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0002 0.0005 0 0.0001 0
Cytoplasm 0.8082 0.9261 0.8671 0.9116 0.8845 0.7155 0.6286 0.8715 0.8047 0.8372 0.8308 0.8278 0.6471 0.7786 0.7372 0.645 0.7115 0.6694
Cytoplasmic Foci 0.0072 0.0018 0.0017 0.0024 0.0121 0.0078 0.0304 0.0026 0.0102 0.0055 0.023 0.0086 0.0347 0.0058 0.0139 0.0105 0.0194 0.0064
Eisosomes 0.0001 0 0 0.003 0 0 0.0007 0 0.0001 0.0003 0 0 0.0003 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.01 0.0051 0.0038 0.0046 0.01 0.0058 0.0088 0.0071 0.0078 0.003 0.0087 0.0039 0.0081 0.0035 0.0046 0.0037 0.005 0.0039
Endosome 0.0235 0.001 0.0027 0.0018 0.0109 0.0033 0.0586 0.0014 0.011 0.0049 0.05 0.0074 0.059 0.0028 0.0172 0.005 0.0284 0.006
Golgi 0.0086 0.0001 0.0031 0.0007 0.0007 0.0005 0.0211 0.0001 0.0035 0.0053 0.0069 0.0043 0.0196 0.0009 0.0058 0.0003 0.034 0.0023
Lipid Particles 0.0188 0.0001 0.001 0.0003 0.0009 0.0003 0.0263 0.0001 0.0009 0.0094 0.0318 0.0038 0.0171 0.0002 0.0025 0.0001 0.014 0.0011
Mitochondria 0.0139 0.0003 0.0121 0.0005 0.0003 0.0124 0.0105 0.0001 0.001 0.0164 0.0015 0.005 0.0113 0.0014 0.0091 0.0005 0.0289 0.0016
None 0.0078 0.0162 0.0361 0.004 0.019 0.0153 0.0666 0.0981 0.1063 0.0815 0.0281 0.0324 0.0277 0.0667 0.0436 0.1121 0.0032 0.0212
Nuclear Periphery 0.0134 0.003 0.0094 0.0026 0.0075 0.0091 0.0079 0.0033 0.0028 0.0013 0.0033 0.0061 0.019 0.0048 0.0055 0.0073 0.0073 0.008
Nucleolus 0.0003 0.0001 0.0002 0 0.0003 0.0003 0.0021 0 0.0001 0.0001 0.0001 0.0002 0.0007 0.0003 0.0002 0.0003 0.0001 0.0004
Nucleus 0.0636 0.0407 0.0558 0.0217 0.0408 0.2128 0.0298 0.0122 0.0358 0.0141 0.003 0.0813 0.057 0.1211 0.1158 0.2002 0.0705 0.2641
Peroxisomes 0.0026 0 0.0003 0.0007 0.0004 0.0005 0.0114 0 0.004 0.0054 0.0047 0.0023 0.0208 0.001 0.0048 0.0006 0.0389 0.0006
Punctate Nuclear 0.0034 0.0005 0.0008 0.0004 0.0068 0.0022 0.0061 0.001 0.0012 0.0006 0.0025 0.0061 0.0135 0.0026 0.0041 0.009 0.0035 0.009
Vacuole 0.0024 0.0018 0.0016 0.0016 0.0022 0.0041 0.0034 0.0005 0.0011 0.0005 0.0013 0.0008 0.0023 0.0007 0.0024 0.0011 0.0021 0.0011
Vacuole Periphery 0.001 0.0001 0.0011 0.0003 0.0004 0.0005 0.0018 0.0001 0.0003 0.0002 0.0004 0.0003 0.0021 0.0001 0.0007 0.0003 0.0019 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.0384 10.2949 7.6392 16.2955 12.1317 10.0712 10.0838 8.7818 13.6375 19.095
Translational Efficiency 0.9494 0.3897 0.6228 0.9057 1.2022 0.4722 0.4065 0.7754 0.9943 0.9261

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2732 209 900 1767 2610 1248 222 780 5342 1457 1122 2547

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1642.19 1477.43 1348.99 1010.12 1797.45 1395.20 1647.20 1005.41 1718.05 1407.00 1407.99 1008.68
Standard Deviation 284.49 289.32 195.14 230.18 301.27 329.60 240.14 187.47 302.92 325.41 236.79 218.00
Intensity Change Log 2 — -0.152531 -0.283741 -0.701094 — -0.365480 -0.125936 -0.838168 — -0.259885 -0.199128 -0.771098

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000157 0.000819 0.000360 0.002317 0.000167 0.000889 0.001359 0.000694 0.000162 0.000879 0.000557 0.001820
Bud Neck 0.007740 0.003228 0.001720 0.013864 0.009154 0.004901 0.005468 0.007661 0.008431 0.004661 0.002462 0.011964
Bud Site 0.001977 0.003458 0.005971 0.037799 0.001265 0.008672 0.011867 0.045760 0.001629 0.007924 0.007138 0.040237
Cell Periphery 0.000096 0.000174 0.000108 0.000134 0.000102 0.000179 0.000221 0.000113 0.000099 0.000178 0.000130 0.000127
Cytoplasm 0.237949* 0.390699* 0.650172* 0.437900* 0.195959* 0.458593* 0.264278* 0.484348* 0.217434* 0.448854* 0.573818* 0.452124*
Cytoplasmic Foci 0.001194 0.014428 0.009288 0.015223 0.000660 0.009334 0.005129 0.015883 0.000933 0.010064 0.008465 0.015425
Eisosomes 0.000004 0.000013 0.000007 0.000022 0.000004 0.000010 0.000019 0.000034 0.000004 0.000010 0.000009 0.000026
Endoplasmic Reticulum 0.000608 0.002228 0.000917 0.002066 0.000718 0.001131 0.002408 0.002205 0.000662 0.001288 0.001212 0.002108
Endosome 0.000157 0.003894 0.001330 0.006312 0.000139 0.002138 0.002420 0.012196 0.000148 0.002390 0.001546 0.008114
Golgi 0.000068 0.002373 0.000226 0.009246 0.000096 0.001056 0.000346 0.004910 0.000082 0.001245 0.000250 0.007918
Lipid Particles 0.000072 0.001095 0.000788 0.001793 0.000086 0.000761 0.001617 0.001677 0.000078 0.000809 0.000952 0.001758
Mitochondria 0.000715 0.000590 0.000299 0.003590 0.000979 0.002596 0.001277 0.008325 0.000844 0.002308 0.000492 0.005040
Mitotic Spindle 0.002375 0.022438 0.006603 0.100918* 0.003593 0.015112 0.015023 0.076806 0.002970 0.016163 0.008269 0.093534
None 0.011707 0.009614 0.007004 0.011096 0.008643 0.009489 0.003382 0.008046 0.010210 0.009507 0.006287 0.010162
Nuclear Periphery 0.000652 0.000638 0.000692 0.001850 0.001138 0.000599 0.002041 0.001305 0.000890 0.000604 0.000959 0.001683
Nuclear Periphery Foci 0.000378 0.007631 0.003771 0.002576 0.000453 0.002126 0.004201 0.001800 0.000415 0.002916 0.003856 0.002338
Nucleolus 0.000633 0.000741 0.000154 0.000646 0.000580 0.000812 0.000308 0.001160 0.000607 0.000802 0.000184 0.000803
Nucleus 0.731244* 0.500747* 0.274244* 0.281772* 0.774181* 0.463052* 0.561553* 0.204083* 0.752222* 0.468459* 0.331091* 0.257980*
Peroxisomes 0.000024 0.000586 0.000101 0.002460 0.000017 0.000997 0.000351 0.001063 0.000021 0.000938 0.000150 0.002032
Vacuole 0.002160 0.034349 0.036114 0.065729 0.001990 0.015640 0.116312 0.117127 0.002077 0.018324 0.051982 0.081469
Vacuole Periphery 0.000089 0.000257 0.000132 0.002689 0.000075 0.001913 0.000420 0.004802 0.000082 0.001676 0.000189 0.003336

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.26 -6.59 -3.64 -0.66 -2.39 -2.64 -4.94 -5.77 0.88 2.95 -3.20 -7.98 -4.27 -0.55 -1.67
Bud Neck 3.95 11.29 -0.27 -3.97 -10.19 6.10 5.13 5.44 -0.09 -0.00 6.52 14.93 2.53 -3.58 -9.63
Bud Site -3.67 -3.49 -8.08 -6.46 -4.70 -5.16 -3.62 -6.00 -3.47 -2.07 -5.19 -4.99 -10.19 -5.32 -5.30
Cell Periphery -5.71 -4.81 -3.83 4.30 2.36 -2.97 -7.82 0.48 3.12 7.95 -3.93 -7.74 -2.92 3.19 6.17
Cytoplasm -5.94 -40.33 -11.71 1.84 28.18 -22.09 -2.71 -16.57 3.96 -7.40 -21.44 -35.96 -20.44 7.24 19.95
Cytoplasmic Foci -4.04 -13.27 -9.21 1.66 2.90 -8.78 -5.64 -11.47 -0.31 -1.69 -9.50 -14.66 -13.18 0.97 2.22
Eisosomes -5.17 -8.22 -25.25 -8.83 -17.35 -5.04 -13.43 -21.43 -14.72 -5.78 -6.24 -13.31 -32.82 -17.57 -18.96
Endoplasmic Reticulum -4.29 -4.92 -17.39 -2.14 -11.75 -6.26 -9.44 -10.10 -7.54 -0.70 -7.89 -8.40 -20.07 -11.90 -10.94
Endosome -2.35 -8.83 -7.97 0.56 -1.94 -4.65 -9.29 -5.26 -2.55 -1.30 -5.20 -11.66 -9.22 -1.76 -2.65
Golgi -1.23 -7.75 -2.74 -0.17 -2.41 -3.30 -6.48 -2.03 -0.53 -1.47 -3.33 -7.97 -3.26 -1.23 -2.78
Lipid Particles -4.57 -12.47 -12.04 -2.50 -3.54 -3.80 -10.27 -7.56 -2.80 3.81 -4.82 -15.63 -14.11 -4.67 -1.52
Mitochondria 0.87 9.69 -5.11 -5.25 -7.08 -1.44 0.33 -1.81 -0.42 -1.84 -1.63 10.56 -3.99 -0.26 -5.49
Mitotic Spindle -2.02 -2.93 -12.91 -4.91 -10.93 -4.45 -3.39 -7.70 -5.28 -1.91 -5.20 -4.27 -14.95 -9.59 -10.73
None 2.19 9.60 0.56 -1.81 -8.45 -1.10 7.14 -1.55 -0.83 -7.52 1.69 10.08 -1.29 -2.85 -10.48
Nuclear Periphery -1.58 -5.32 -22.01 -18.89 -19.42 6.60 -9.36 -10.10 -13.42 1.97 2.84 -6.91 -23.11 -23.77 -17.43
Nuclear Periphery Foci -3.13 -10.64 -6.76 1.90 2.65 -3.26 -7.77 -6.95 0.83 4.97 -4.49 -12.60 -8.11 0.69 4.36
Nucleolus -0.25 7.54 -1.02 -0.37 -6.62 -0.75 4.08 -0.46 0.14 -2.85 -0.51 8.65 -1.31 -0.55 -7.23
Nucleus 8.67 52.92* 42.83* 5.67 -9.95 25.32 15.12 44.71* 14.13 5.00 25.64 54.96 61.79* 14.05 -5.03
Peroxisomes -1.58 -5.54 -3.47 -0.44 -2.94 -2.97 -2.60 -5.06 1.58 -1.03 -3.20 -5.58 -4.26 0.68 -3.25
Vacuole -5.75 -16.36 -31.40 -13.31 -14.02 -11.02 -14.06 -24.20 -21.44 1.96 -12.26 -19.86 -39.51 -31.81 -10.58
Vacuole Periphery -2.44 -3.72 -2.38 -1.64 -2.01 -2.37 -2.95 -3.07 0.44 -2.30 -2.40 -5.12 -3.73 0.94 -3.08
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcriptional activator of nitrogen catabolite repression genes; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p; different translational starts produce two major and two minor isoforms that are differentially regulated and localized
Localization
Cell Percentages cytoplasm (38%), nucleus (1%), mixed (61%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Gat1

Gat1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gat1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available