Standard name
Human Ortholog
Description Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.95 0.98 0.99 0.98 0.95 0.93 0.89 0.86 0.84 0.8 0.81 0.99 0.99 0.99 0.97 0.98 0.99 0.87 0.84 0.78 0.92 0.85 0.85
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.05 0 0.07 0 0.17 0.22 0.21 0.34 0.37 0.41 0.39 0 0 0 0 0 0 0 0 0.1 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 2 6 7
Bud 0 0 0 3 1 2 9 12 4 10 5 5 0 0 9 0 0 0 0 1 3 3 19 10
Bud Neck 1 0 3 1 3 1 7 7 1 0 1 0 0 1 0 0 1 0 0 0 1 1 2 2
Bud Site 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 2 4 10 1 7 6 4 9 5 7 2 2 8 12 9 12 0 0 2 0 2 2
Cytoplasm 201 179 303 210 524 410 618 508 332 457 267 340 274 479 528 374 291 263 181 163 217 284 487 382
Endoplasmic Reticulum 1 1 1 0 2 0 0 1 1 2 0 0 1 1 3 19 10 14 1 0 1 0 2 2
Endosome 0 0 0 0 1 0 4 1 0 0 0 0 0 1 0 0 1 1 3 1 3 0 7 3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 2 3 0 1 3 0
Mitochondria 1 9 6 15 23 74 146 120 130 201 136 162 1 0 7 6 1 2 7 7 28 4 17 20
Nucleus 0 0 1 0 1 0 0 4 2 4 0 2 0 1 1 4 1 2 0 1 1 0 1 1
Nuclear Periphery 0 1 0 0 1 0 0 0 1 0 0 0 0 0 2 0 1 0 1 0 0 0 0 0
Nucleolus 0 1 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 2 0 1 1 0 2 3 3 2 0 0 0 0 0 0 0 2 2 1 2 7 5
Vac/Vac Membrane 1 4 0 0 5 1 5 2 1 2 0 4 0 2 0 8 7 2 0 2 2 2 4 5
Unique Cell Count 205 189 309 212 537 431 662 569 387 542 334 420 276 486 534 384 296 267 209 195 278 308 575 449
Labelled Cell Count 207 195 318 233 573 490 796 663 481 689 416 520 278 489 558 425 322 297 209 195 278 308 575 449


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.8 4.0 3.4 3.0 3.6 3.2 3.3 3.5 2.9 3.0 2.8 2.8 4.6 4.7 4.2 7.0 7.4 7.3 4.6 4.6 5.2
Std Deviation (1e-4) 0.8 1.1 1.2 1.2 1.6 1.2 1.3 1.5 0.9 1.3 0.7 0.9 1.3 1.2 1.1 1.3 1.5 1.4 1.1 1.4 1.6
Intensity Change (Log2) – – – -0.15 0.12 -0.05 -0.03 0.07 -0.22 -0.14 -0.26 -0.25 0.45 0.5 0.32 1.06 1.14 1.12 0.47 0.45 0.62


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.6547 1.4287 1.4256 0.9191 1.1323 1.3348 2.3972 2.1982 2.1311 1.9051 1.8011 2.2551 2.4151 3.118 2.4689 3.5903 2.557 2.7127
Actin 0.0529 0.0002 0.028 0.0218 0.0365 0.0223 0.0642 0.0022 0.0224 0.0006 0.0121 0.0015 0.0001 0.0001 0.0044 0.0002 0.0008 0.0094
Bud 0.0003 0.0027 0.0013 0.0003 0.0008 0.0002 0.0139 0.0111 0.0112 0.0123 0.0017 0.0024 0 0 0.0005 0 0.0001 0.0003
Bud Neck 0.0016 0.0003 0.0008 0.0009 0.0085 0.0006 0.0104 0.0024 0.0043 0.0014 0.0003 0.0011 0 0.0001 0.0003 0.0001 0.0002 0.0003
Bud Periphery 0.0004 0.0007 0.001 0.0004 0.0017 0.0003 0.0069 0.0051 0.0037 0.0079 0.0053 0.0015 0 0 0.0009 0 0.0002 0.0005
Bud Site 0.0051 0.0042 0.0062 0.0008 0.0296 0.0002 0.014 0.0287 0.0157 0.0015 0.0005 0.0015 0.0001 0.0003 0.0011 0.0001 0.0001 0.0001
Cell Periphery 0.0004 0.0005 0.0006 0.0002 0.0003 0.0001 0.0014 0.0007 0.0004 0.0002 0.0004 0.0001 0.0001 0.0002 0.0003 0.0001 0.0001 0.0001
Cytoplasm 0.2859 0.5373 0.4125 0.3584 0.2247 0.5547 0.1468 0.2366 0.1752 0.153 0.112 0.2367 0.2455 0.3394 0.3721 0.3334 0.3116 0.3893
Cytoplasmic Foci 0.0199 0.0126 0.0062 0.0137 0.0339 0.0056 0.0275 0.0066 0.0136 0.0051 0.0084 0.0049 0.0025 0.0035 0.0083 0.0035 0.008 0.0049
Eisosomes 0.0009 0.0001 0.0006 0.0002 0.0004 0.0002 0.0008 0.0001 0.0002 0.0001 0.001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0049 0.0049 0.0028 0.003 0.0035 0.0048 0.0063 0.0008 0.0013 0.0004 0.0025 0.0006 0.0009 0.0037 0.0031 0.0015 0.0022 0.0024
Endosome 0.0121 0.0026 0.0042 0.012 0.022 0.0041 0.0422 0.0018 0.0071 0.0015 0.002 0.0028 0.0003 0.0015 0.0043 0.0016 0.0015 0.0017
Golgi 0.0041 0.0002 0.0034 0.0065 0.0168 0.0017 0.0123 0.0002 0.0025 0.0001 0.0008 0.0008 0 0.0001 0.0012 0.0001 0.0002 0.0007
Lipid Particles 0.0107 0.0004 0.0018 0.0112 0.0286 0.0008 0.0251 0.0002 0.0037 0 0.0054 0.0023 0.0001 0.0002 0.0014 0.0001 0.0004 0.0005
Mitochondria 0.0025 0.0004 0.0137 0.0125 0.0114 0.001 0.0161 0.0008 0.0017 0.0008 0.001 0.0044 0.0001 0.0001 0.0067 0.0001 0.0003 0.0003
None 0.5696 0.4248 0.5097 0.5394 0.5368 0.3998 0.579 0.6964 0.7219 0.8078 0.8399 0.727 0.7493 0.649 0.5883 0.6572 0.6706 0.5851
Nuclear Periphery 0.0052 0.0009 0.0014 0.001 0.0031 0.0011 0.0055 0.0004 0.0011 0.0005 0.0013 0.0029 0.0002 0.0004 0.0011 0.0004 0.0006 0.0011
Nucleolus 0.0005 0.0004 0.0002 0.0004 0.0004 0.0001 0.001 0.0006 0.0011 0.0003 0.0007 0.0003 0 0.0001 0.0004 0.0001 0.0001 0.0001
Nucleus 0.0061 0.0019 0.0009 0.0006 0.001 0.0007 0.0029 0.0023 0.0034 0.0042 0.0008 0.0026 0.0004 0.0005 0.0011 0.0005 0.0009 0.0009
Peroxisomes 0.0091 0.0004 0.0013 0.0131 0.035 0.0004 0.0103 0.0003 0.0047 0.0002 0.0011 0.0006 0 0 0.0006 0.0001 0.0002 0.0006
Punctate Nuclear 0.0059 0.0025 0.0016 0.001 0.0015 0.0006 0.0085 0.0014 0.0031 0.0009 0.0015 0.0054 0.0002 0.0002 0.0013 0.0004 0.0009 0.0013
Vacuole 0.0014 0.002 0.0014 0.0019 0.0019 0.0007 0.0034 0.0012 0.0014 0.001 0.0011 0.0004 0.0002 0.0006 0.0019 0.0004 0.0006 0.0004
Vacuole Periphery 0.0004 0.0002 0.0004 0.0006 0.0015 0.0002 0.0016 0.0002 0.0003 0.0002 0.0003 0.0002 0 0 0.0004 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.4494 10.9535 10.8833 14.4788 9.6936 12.2463 14.7825 14.3798 13.7888 16.1424
Translational Efficiency 0.5423 0.4391 0.4523 0.3172 0.5739 0.5335 0.4022 0.4164 0.4713 0.4155

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1538 1225 1598 1498 2180 2041 1172 1575 3718 3266 2770 3073

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 622.65 671.63 953.82 843.35 654.90 695.67 836.63 810.77 641.56 686.65 904.24 826.65
Standard Deviation 85.14 87.54 122.39 111.71 70.60 92.59 120.19 118.89 78.57 91.47 134.56 116.59
Intensity Change Log 2 — 0.109245 0.615296 0.437710 — 0.087128 0.353315 0.308018 — 0.097950 0.486942 0.372684

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000083 0.000409 0.000180 0.000305 0.000107 0.000333 0.000076 0.000927 0.000097 0.000361 0.000136 0.000624
Bud Neck 0.018497 0.039523 0.002623 0.005892 0.023468 0.049749 0.002789 0.005925 0.021412 0.045913 0.002693 0.005909
Bud Site 0.012808 0.017118 0.013422 0.018673 0.006679 0.020876 0.002728 0.022296 0.009215 0.019466 0.008897 0.020530
Cell Periphery 0.000409 0.000122 0.000147 0.000108 0.000122 0.000201 0.000289 0.000142 0.000241 0.000171 0.000207 0.000126
Cytoplasm 0.611713* 0.372907* 0.419884* 0.565297* 0.464192* 0.358810* 0.508964* 0.570934* 0.525216* 0.364097* 0.457574* 0.568186*
Cytoplasmic Foci 0.108249 0.284107* 0.007787 0.020876 0.211392* 0.241566* 0.019303 0.016524 0.168725 0.257522* 0.012660 0.018646
Eisosomes 0.000162 0.000149 0.000029 0.000033 0.000148 0.000164 0.000098 0.000033 0.000154 0.000158 0.000058 0.000033
Endoplasmic Reticulum 0.001346 0.000745 0.002252 0.001177 0.001260 0.001063 0.000971 0.001497 0.001295 0.000944 0.001710 0.001341
Endosome 0.005775 0.031599 0.001550 0.008446 0.010446 0.034670 0.002047 0.002212 0.008513 0.033518 0.001760 0.005251
Golgi 0.000815 0.008125 0.000063 0.002625 0.002423 0.007952 0.000482 0.002422 0.001757 0.008017 0.000240 0.002521
Lipid Particles 0.005153 0.008715 0.000883 0.003806 0.009364 0.010715 0.001197 0.000773 0.007622 0.009965 0.001016 0.002251
Mitochondria 0.002833 0.020299 0.000594 0.005244 0.007913 0.024022 0.000616 0.002562 0.005812 0.022626 0.000603 0.003869
Mitotic Spindle 0.000731 0.007258 0.002217 0.042549 0.004613 0.011895 0.006030 0.032619 0.003007 0.010156 0.003830 0.037460
None 0.012712 0.004598 0.008388 0.007789 0.005176 0.004565 0.014378 0.005040 0.008294 0.004577 0.010922 0.006380
Nuclear Periphery 0.000678 0.000684 0.001721 0.001249 0.000715 0.000471 0.001099 0.000907 0.000700 0.000550 0.001457 0.001074
Nuclear Periphery Foci 0.000297 0.000762 0.000901 0.000946 0.000227 0.000310 0.000730 0.000704 0.000256 0.000480 0.000828 0.000822
Nucleolus 0.001799 0.003125 0.000349 0.000595 0.001402 0.002786 0.000505 0.000204 0.001566 0.002913 0.000415 0.000395
Nucleus 0.170449* 0.098159 0.473761* 0.180586* 0.193284* 0.119140 0.380541* 0.232935* 0.183838* 0.111271 0.434319* 0.207417*
Peroxisomes 0.001597 0.027391 0.000132 0.001708 0.005009 0.014953 0.000875 0.000739 0.003598 0.019619 0.000446 0.001211
Vacuole 0.042466 0.070855 0.062552 0.129371 0.050486 0.091378 0.056026 0.100369 0.047168 0.083680 0.059791 0.114507
Vacuole Periphery 0.001429 0.003351 0.000565 0.002726 0.001575 0.004381 0.000257 0.000236 0.001515 0.003994 0.000435 0.001450

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.79 -7.63 -6.38 2.39 1.04 -3.22 -1.33 -2.80 -1.18 -2.68 -5.42 -7.66 -3.87 -0.42 -2.18
Bud Neck -6.99 10.32 8.95 13.17 -3.65 -10.26 14.53 12.50 20.18 -2.66 -12.55 17.85 15.47 24.17 -4.12
Bud Site -1.91 1.70 0.94 3.13 -0.90 -8.23 4.16 -3.05 4.28 -5.80 -7.49 2.26 -1.68 5.45 -3.64
Cell Periphery 4.99 4.70 5.63 4.12 2.45 -5.44 -4.62 2.16 6.30 5.49 2.74 2.90 6.05 7.73 5.25
Cytoplasm 22.81 31.00 17.15 -6.53 -11.87 12.73 2.39 0.45 -10.81 -1.82 24.49 21.91 10.81 -12.49 -10.53
Cytoplasmic Foci -23.62 30.80 27.78 40.07 -8.53 -4.58 42.38 43.73 45.66 2.35 -17.69 50.84 49.74 60.47 -4.47
Eisosomes 0.97 9.99 9.65 13.16 -2.11 -1.10 4.96 10.43 13.05 4.71 -0.36 11.10 14.17 17.53 3.86
Endoplasmic Reticulum 1.77 -7.77 -1.67 -7.75 10.90 0.74 -2.62 -3.29 -4.84 -1.11 1.66 -8.96 -3.47 -7.62 9.06
Endosome -12.65 9.25 3.20 13.55 -3.52 -14.46 12.80 13.84 21.34 2.34 -19.35 15.73 12.26 24.76 -2.33
Golgi -8.78 8.87 -0.03 8.41 -2.96 -7.92 6.14 2.43 8.13 -0.90 -11.71 8.56 2.53 11.86 -2.00
Lipid Particles -3.02 6.14 3.96 6.30 -1.57 -1.39 12.21 12.76 11.61 2.15 -3.03 13.59 11.67 12.57 -1.07
Mitochondria -7.50 3.67 0.81 7.76 -2.23 -9.17 10.25 7.30 13.44 -1.39 -12.02 10.66 6.35 15.26 -2.56
Mitotic Spindle -4.10 -3.73 -9.60 -6.19 -8.57 -3.78 -0.45 -5.37 -2.50 -4.75 -5.41 -1.11 -10.22 -5.85 -9.54
None 5.03 4.37 4.48 -1.26 0.07 0.49 -2.95 -0.22 -0.96 3.21 3.98 0.51 3.11 -1.62 2.51
Nuclear Periphery 0.00 -11.51 -9.55 -9.86 2.44 1.30 -5.11 -5.69 -18.53 -1.33 1.07 -11.63 -10.30 -19.05 2.24
Nuclear Periphery Foci -2.68 -10.18 -7.75 -1.03 4.04 -1.85 -8.12 -9.37 -7.00 1.11 -3.18 -13.28 -12.30 -5.21 3.97
Nucleolus -2.17 5.74 5.11 4.26 -2.03 -4.90 7.31 8.51 9.32 2.32 -4.51 9.13 8.96 8.70 -0.02
Nucleus 11.11 -40.89 -9.82 -20.00 30.14 14.07 -22.19 -13.03 -23.81 10.42 17.68 -45.09 -15.88 -30.61 28.79
Peroxisomes -12.38 8.33 4.07 12.87 -2.71 -10.29 9.15 13.79 16.15 0.60 -16.17 12.75 13.75 19.77 -0.87
Vacuole -7.47 -14.04 -27.19 -21.80 -14.72 -11.69 -11.36 -22.24 -14.50 -8.65 -13.93 -17.97 -34.89 -25.27 -16.53
Vacuole Periphery -4.24 4.48 1.58 4.78 -1.69 -8.29 7.88 8.98 14.27 0.64 -9.20 7.80 5.49 12.42 -1.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase
Localization
Cell Percentages cytoplasm (32%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Rim15

Rim15


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rim15-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available