Standard name
Human Ortholog
Description Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0.06 0 0 0 – 0 0 0.05 0.12 0.15 0.12 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.06 0 0 0 0.05 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.08 0.35 0.56 0.33 0.59 0.5 0.59 0.75 – 0.74 0.79 0 0 0.14 0.06 0 0.06 0 0 0 0 0 0
Nucleus 0.81 0.82 0.86 0.78 0.66 0.62 0.66 0.6 0.57 – 0.64 0.55 0.88 0.81 0.71 0.72 0.74 0.68 0.64 0.73 0.75 0.69 0.67 0.54
Nuclear Periphery 0 0 0 0 0 0 0.05 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.12 0.09 0 0.09 0.18 0.17 0.15 0.17 0.16 – 0.13 0.17 0 0 0.05 0.07 0.11 0.13 0.18 0.09 0.08 0.07 0.05 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0.07 0.11 0 0.06 0.07 0.09 0.17 0.24
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Bud 0 0 0 0 2 2 17 17 9 – 5 7 0 0 0 0 1 0 0 1 2 1 5 2
Bud Neck 0 0 1 0 0 0 1 2 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Bud Site 0 0 0 0 2 16 17 29 14 – 11 21 0 1 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9 7 6 7 16 25 21 22 13 – 8 6 14 41 57 24 13 13 0 2 1 0 1 2
Endoplasmic Reticulum 1 3 1 0 0 0 0 0 0 – 0 0 0 1 1 6 8 6 1 1 1 0 1 1
Endosome 8 2 0 0 8 3 4 1 2 – 1 1 2 0 2 3 7 10 15 6 1 7 5 16
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 1 1 0 0 0 1
Mitochondria 13 15 57 119 123 258 302 494 311 – 258 469 6 7 53 12 4 11 7 3 1 1 6 7
Nucleus 294 159 140 165 247 269 397 500 234 – 223 323 235 270 266 147 110 119 252 149 121 110 209 161
Nuclear Periphery 6 6 0 0 12 5 28 10 6 – 8 17 1 6 4 0 2 4 14 0 1 0 0 2
Nucleolus 44 18 7 20 67 74 89 141 66 – 45 100 5 14 20 15 16 22 69 19 12 11 14 21
Peroxisomes 1 0 0 0 1 0 1 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 5 0 1 2 13 10 21 26 7 – 2 8 1 1 0 2 5 2 14 4 3 5 8 5
Vac/Vac Membrane 12 9 2 0 4 3 12 16 1 – 4 8 14 12 13 9 10 20 10 12 11 14 52 72
Unique Cell Count 364 195 162 212 372 436 604 835 413 351 590 266 335 377 203 148 174 395 205 162 160 313 300
Labelled Cell Count 393 219 215 313 495 665 910 1258 663 565 961 278 353 417 219 176 207 395 205 162 160 313 300


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.3 5.9 4.3 4.1 4.4 4.0 4.0 3.8 3.3 – 3.4 3.1 6.0 6.1 5.5 8.0 8.6 8.9 5.9 5.8 6.2
Std Deviation (1e-4) 1.4 1.1 0.6 0.7 1.2 1.0 1.3 0.9 0.8 – 1.0 0.8 1.1 1.5 1.5 1.8 2.2 2.2 1.1 1.4 1.3
Intensity Change (Log2) – – – -0.06 0.04 -0.1 -0.11 -0.17 -0.36 – -0.35 -0.47 0.48 0.52 0.35 0.91 1.01 1.06 0.45 0.43 0.55


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm -0.2 0.3 1.0 -0.1 0 -0.3 – 0 0 0.7 3.0 3.8 2.8 1.9 1.5
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 – 0 0 -9.3 -10.3 -5.6 -7.1 -7.2 -6.6
Nucleus -2.1 -4.8 -5.8 -5.1 -6.4 -6.7 – -5.3 -7.3 0.6 -1.6 -3.9 -3.2 -2.7 -3.9
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 -0.1 0.5 1.2 2.2 2.7
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 – 0 0 2.1 0 0 0 2.5 3.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.8614 3.6023 3.7757 3.2805 3.4715 3.7861 3.2083 2.9834 3.1021 2.6843 2.6465 2.639 0.9851 1.1323 0.9192 0.8475 0.5554 0.8487
Actin 0 0.0001 0.0006 0.0001 0.0001 0.0001 0.0918 0.0002 0.0225 0.0024 0.0035 0.0008 0.0037 0.0002 0.0203 0.0002 0.0075 0.0001
Bud 0 0.0001 0.0002 0.0002 0.0001 0.0001 0.0007 0.0001 0.0008 0.0006 0.0005 0.0001 0.0003 0.0001 0.0003 0.0001 0.0004 0
Bud Neck 0.0002 0.0018 0.0027 0.0029 0.0186 0.0106 0.0065 0.0009 0.0012 0.0027 0.0128 0.0028 0.0006 0.0011 0.0022 0.0013 0.013 0.003
Bud Periphery 0 0.0001 0.0005 0.0003 0.0005 0.0002 0.001 0.0001 0.0009 0.0014 0.0018 0.0003 0.0002 0.0002 0.0008 0.0002 0.0019 0.0001
Bud Site 0.0001 0.0006 0.001 0.0009 0.0017 0.0003 0.0105 0.0009 0.0034 0.0026 0.001 0.0002 0.0009 0.0006 0.0035 0.0006 0.0018 0.0001
Cell Periphery 0 0 0.0003 0.0002 0.0003 0.0001 0.0005 0.0001 0.0002 0.0003 0.0004 0.0001 0.0001 0.0001 0.0002 0.0001 0.0005 0
Cytoplasm 0.0004 0.004 0.0015 0.0006 0.0001 0.0004 0.0063 0.0088 0.0088 0.0012 0.0006 0.0003 0.0057 0.0213 0.0081 0.0046 0.0007 0.001
Cytoplasmic Foci 0 0.0001 0.0004 0.0005 0.0019 0.0005 0.0294 0.0007 0.0071 0.0081 0.0069 0.0007 0.0119 0.0017 0.0077 0.0007 0.005 0.0002
Eisosomes 0 0 0 0 0 0 0.001 0 0.0001 0 0.0002 0 0.0001 0 0.0003 0 0.0006 0
Endoplasmic Reticulum 0.0001 0.0003 0.0006 0.0004 0 0.0001 0.0062 0.001 0.0013 0.002 0.0013 0.0002 0.0046 0.0011 0.0019 0.0033 0.0006 0.0001
Endosome 0.0001 0.0002 0.0025 0.0008 0.0007 0.0006 0.0386 0.0011 0.0092 0.0166 0.0149 0.0036 0.0104 0.0015 0.0082 0.0043 0.0071 0.0003
Golgi 0 0 0.0004 0.0002 0.0006 0.0001 0.0129 0.0001 0.0056 0.0029 0.015 0.0028 0.0013 0.0002 0.003 0.0003 0.0038 0
Lipid Particles 0 0.0001 0.0009 0.0027 0.0056 0.0006 0.0491 0.0001 0.0046 0.0076 0.0361 0.0098 0.0049 0.0018 0.0119 0.0034 0.017 0.0006
Mitochondria 0.0002 0.0002 0.0008 0.0003 0.0003 0.0002 0.0053 0.0005 0.0064 0.0039 0.0217 0.013 0.0018 0.0004 0.0057 0.0003 0.0152 0.0003
None 0.0001 0.0004 0.0008 0.0005 0.0002 0.0001 0.0097 0.0002 0.001 0.0006 0.0008 0.0001 0.0057 0.0039 0.0186 0.0011 0.0021 0.0005
Nuclear Periphery 0.0075 0.0066 0.0277 0.035 0.0019 0.0073 0.0754 0.0267 0.0344 0.0385 0.0722 0.0153 0.0173 0.0596 0.0629 0.0375 0.0302 0.0094
Nucleolus 0.0349 0.092 0.1291 0.3705 0.4608 0.0952 0.0144 0.037 0.1266 0.2918 0.2704 0.1103 0.0395 0.1031 0.1357 0.2971 0.4047 0.0921
Nucleus 0.9499 0.8585 0.7952 0.4744 0.2584 0.8586 0.6039 0.8877 0.7088 0.5602 0.4103 0.7972 0.8708 0.7498 0.6419 0.5564 0.3333 0.8439
Peroxisomes 0 0 0.0002 0.0001 0.0004 0.0001 0.0139 0 0.0046 0.0126 0.0051 0.0007 0.0007 0.0005 0.0084 0.0001 0.0038 0
Punctate Nuclear 0.0061 0.0343 0.0312 0.107 0.2467 0.0242 0.0155 0.0312 0.0449 0.0376 0.1171 0.0404 0.0179 0.0511 0.0546 0.0856 0.1465 0.0475
Vacuole 0.0002 0.0004 0.0028 0.001 0.001 0.0006 0.0037 0.0016 0.005 0.004 0.004 0.0006 0.0012 0.0012 0.0019 0.0021 0.0023 0.0003
Vacuole Periphery 0.0001 0.0001 0.0008 0.0014 0.0001 0.0001 0.0037 0.0009 0.0027 0.0024 0.0036 0.0009 0.0005 0.0006 0.0016 0.0007 0.002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.1503 12.3543 9.7925 12.2609 13.2351 14.1263 14.4077 15.233 12.6024 15.8805
Translational Efficiency 0.7781 0.5965 0.4998 0.4498 0.4569 0.5563 0.4672 0.3232 0.4016 0.4348

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1513 1461 1420 699 2013 444 178 301 3526 1905 1598 1000

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.25 840.25 1043.42 978.88 782.71 836.53 1075.78 960.35 760.63 839.38 1047.02 973.30
Standard Deviation 97.10 125.78 147.68 127.00 102.38 128.05 111.60 112.65 103.33 126.32 144.46 123.15
Intensity Change Log 2 — 0.200454 0.512883 0.420767 — 0.095939 0.458833 0.295082 — 0.147366 0.485193 0.357157

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000284 0.000514 0.000709 0.001252 0.000261 0.000662 0.001937 0.001566 0.000271 0.000549 0.000846 0.001347
Bud Neck 0.003182 0.010474 0.032480 0.023938 0.006458 0.006107 0.009978 0.012372 0.005052 0.009456 0.029974 0.020457
Bud Site 0.000521 0.002057 0.002854 0.006957 0.000601 0.001852 0.001582 0.002728 0.000567 0.002009 0.002713 0.005684
Cell Periphery 0.000070 0.000086 0.000067 0.000114 0.000055 0.000061 0.000067 0.000128 0.000061 0.000080 0.000067 0.000118
Cytoplasm 0.014430 0.010216 0.001931 0.028394 0.003906 0.007310 0.000791 0.015416 0.008422 0.009538 0.001804 0.024488
Cytoplasmic Foci 0.001855 0.002181 0.000064 0.001112 0.000489 0.002933 0.000145 0.001650 0.001075 0.002356 0.000073 0.001274
Eisosomes 0.000036 0.000033 0.000021 0.000041 0.000022 0.000041 0.000069 0.000060 0.000028 0.000034 0.000027 0.000047
Endoplasmic Reticulum 0.001900 0.005324 0.004229 0.010384 0.003226 0.004999 0.012150 0.011058 0.002657 0.005248 0.005112 0.010587
Endosome 0.000913 0.001483 0.000276 0.003558 0.000513 0.003759 0.000566 0.005074 0.000685 0.002013 0.000309 0.004015
Golgi 0.000470 0.000922 0.000136 0.001578 0.000273 0.001081 0.000327 0.008442 0.000357 0.000959 0.000157 0.003644
Lipid Particles 0.000961 0.000904 0.000123 0.000679 0.000532 0.001771 0.000547 0.001001 0.000716 0.001106 0.000170 0.000775
Mitochondria 0.002986 0.003425 0.001618 0.005167 0.001650 0.007650 0.001623 0.001864 0.002223 0.004409 0.001618 0.004173
Mitotic Spindle 0.005336 0.015760 0.010762 0.248906* 0.004497 0.019151 0.062228 0.185030* 0.004857 0.016550 0.016495 0.229679*
None 0.012669 0.006052 0.001431 0.011060 0.003639 0.005059 0.001899 0.010303 0.007513 0.005820 0.001483 0.010832
Nuclear Periphery 0.000882 0.003501 0.001114 0.006458 0.002632 0.002631 0.002023 0.003361 0.001881 0.003298 0.001215 0.005526
Nuclear Periphery Foci 0.009683 0.008552 0.000730 0.008194 0.005156 0.008426 0.010937 0.014148 0.007099 0.008522 0.001867 0.009986
Nucleolus 0.273207* 0.155224 0.046871 0.074872 0.157626 0.130754 0.145574 0.064743 0.207221 0.149521 0.057866 0.071823
Nucleus 0.668287* 0.769210* 0.892523* 0.540595* 0.807501* 0.788189* 0.741524* 0.639460* 0.747764* 0.773633* 0.875703* 0.570354*
Peroxisomes 0.001283 0.001204 0.000334 0.000783 0.000539 0.003161 0.002092 0.000830 0.000858 0.001660 0.000530 0.000797
Vacuole 0.000812 0.002278 0.001502 0.021801 0.000276 0.002520 0.003644 0.019060 0.000506 0.002334 0.001740 0.020976
Vacuole Periphery 0.000233 0.000604 0.000224 0.004157 0.000150 0.001886 0.000297 0.001707 0.000186 0.000903 0.000232 0.003419

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.75 -13.70 -17.66 -14.99 -10.76 -3.68 -10.71 -11.88 -7.04 1.17 -6.92 -17.31 -21.33 -16.60 -10.58
Bud Neck -9.38 -20.18 -16.37 -13.10 -1.03 -0.11 -5.55 -7.98 -7.57 -3.15 -6.94 -19.71 -17.53 -14.71 -0.14
Bud Site -3.72 -4.07 -11.15 -8.36 -6.23 -2.08 -5.68 -8.33 -2.43 -3.04 -4.16 -4.47 -12.70 -8.68 -6.08
Cell Periphery -1.26 -0.12 -6.66 -2.81 -6.04 -0.72 -2.35 -4.55 -3.54 -2.64 -1.87 -1.33 -8.28 -3.63 -6.18
Cytoplasm 1.46 6.67 -1.55 -2.88 -7.20 -1.47 4.84 -3.67 -1.36 -5.41 -1.00 7.44 -4.22 -3.05 -8.44
Cytoplasmic Foci 0.17 4.31 3.52 3.54 -3.23 -2.67 2.18 -0.12 2.59 -1.79 -2.15 4.93 3.09 4.31 -3.76
Eisosomes 2.02 7.20 -6.97 -8.85 -13.49 -4.90 -9.48 -8.85 -4.04 0.94 -3.52 -0.41 -13.00 -9.61 -12.73
Endoplasmic Reticulum -10.41 -13.39 -15.10 -10.00 -11.38 -3.56 -8.25 -10.43 -7.85 -1.08 -9.18 -12.33 -17.68 -12.60 -12.60
Endosome -1.59 2.75 -4.29 -2.19 -8.96 -1.57 -1.59 -2.89 0.51 -2.53 -2.57 2.20 -5.88 -0.68 -7.86
Golgi -0.55 3.58 0.15 0.64 -3.07 -1.83 -1.71 -1.06 -0.59 -0.98 -1.83 3.59 -1.20 -0.29 -1.73
Lipid Particles 0.19 4.13 0.90 0.69 -7.41 -1.75 -0.21 -1.91 1.24 -1.91 -1.64 4.84 -0.69 1.34 -8.38
Mitochondria -0.55 1.00 -2.37 -2.57 -7.08 -2.27 -0.85 -3.26 1.80 -3.89 -2.73 0.25 -4.51 -0.06 -7.62
Mitotic Spindle -3.99 -1.70 -13.75 -12.39 -13.22 -2.94 -4.03 -7.31 -6.06 -2.45 -5.27 -4.22 -15.58 -13.72 -13.82
None 4.82 9.58 2.68 -2.48 -8.40 -0.97 3.91 -2.20 -1.06 -3.37 2.12 10.82 -0.80 -2.55 -8.88
Nuclear Periphery -6.53 -3.87 -12.00 -7.24 -11.22 -0.09 0.41 -3.94 -3.74 -3.73 -3.93 1.41 -11.19 -7.91 -12.31
Nuclear Periphery Foci 0.93 7.88 2.01 1.07 -4.89 -1.20 -0.92 -0.81 0.00 0.24 -0.92 7.28 0.25 0.94 -4.49
Nucleolus 12.34 25.22* 18.98 7.92 -3.70 2.41 0.92 8.89 4.86 4.60 8.33 23.01 18.29 9.50 -2.10
Nucleus -9.18 -21.17 3.64 10.80 19.44 1.43 3.66 5.68 3.91 1.06 -2.86 -14.64 9.62 10.98 18.80
Peroxisomes 0.55 4.80 3.80 2.66 -3.47 -2.03 -4.66 -0.62 1.93 4.32 -2.04 2.66 2.43 3.09 -0.41
Vacuole -2.27 -3.93 -9.26 -8.61 -8.86 -2.86 -6.25 -6.47 -5.49 -4.71 -3.67 -8.42 -11.17 -10.10 -10.30
Vacuole Periphery -2.61 -0.86 -2.07 -1.14 -2.00 -1.90 -6.80 -2.13 1.24 -1.26 -3.04 -4.40 -2.61 -0.25 -2.31
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus
Localization
Cell Percentages nucleus (74%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Smc2

Smc2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Smc2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available