Standard name
Human Ortholog
Description Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p; function is regulated by phosphorylation at multiple sites and by phosphate availability
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.73 0.92 0.79 0.63 0.71 0.76 0.68 0.73 0.58 0.7 0.52 0.6 0.93 0.98 1.0 0.46 0.44 0.45 0.47 0.6 0.56 0.7 0.78 0.75
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.08 0.09 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.23 0 0.09 0.18 0.06 0.2 0.38 0.29 0.49 0.36 0.65 0.47 0 0 0 0 0.05 0 0.1 0.13 0.12 0 0.07 0.07
Nucleus 0.11 0 0.12 0.19 0.12 0 0 0.05 0.08 0 0 0.05 0 0 0 0.26 0.23 0.25 0.14 0.07 0.09 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0 0 0.05 0 0 0.05
Vac/Vac Membrane 0.09 0.1 0.07 0.05 0.14 0.07 0.05 0 0 0 0 0 0.05 0 0 0.25 0.29 0.25 0.12 0.1 0.1 0.09 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 2 2 0 4 4 8
Bud 0 0 0 1 3 0 6 6 8 13 11 0 0 0 0 0 0 1 4 1 0 4 5 9
Bud Neck 0 0 1 2 9 2 3 12 9 10 1 3 2 0 2 2 1 0 0 0 0 1 2 3
Bud Site 0 0 0 0 0 0 1 1 7 1 3 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 1 3 1 0 1 0 0 0 0 1 2 0 0 0 1 0 1 2 3
Cytoplasm 138 107 59 92 166 169 308 303 212 215 179 198 286 447 462 131 68 82 90 78 58 159 283 320
Endoplasmic Reticulum 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 17 5 4 3 0 0 2 0 1
Endosome 0 0 1 2 1 0 1 1 1 2 0 0 2 1 0 18 12 16 4 1 1 1 2 5
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 1 0 2
Mitochondria 43 5 7 27 14 45 174 119 177 111 222 156 1 2 0 3 7 6 18 16 12 10 23 30
Nucleus 20 3 9 28 29 8 19 20 28 13 14 17 8 1 2 73 35 46 27 9 9 6 1 1
Nuclear Periphery 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 1 6 7 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 1
SpindlePole 1 0 0 3 2 0 8 5 4 9 2 3 0 0 0 8 11 11 8 1 5 7 13 19
Vac/Vac Membrane 17 12 5 8 32 16 23 11 11 4 15 11 15 8 1 70 45 45 23 13 10 20 13 5
Unique Cell Count 190 116 75 146 233 221 452 414 363 309 344 329 306 455 463 285 154 183 192 131 104 229 363 426
Labelled Cell Count 221 127 83 164 257 241 546 480 458 380 448 390 314 459 469 328 190 219 192 131 104 229 363 426


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 4.2 4.3 4.8 4.7 3.9 3.5 4.0 3.4 3.4 3.1 3.4 4.9 4.9 4.8 5.8 6.4 5.7 4.6 5.1 4.8
Std Deviation (1e-4) 2.0 0.9 0.9 1.9 1.3 1.5 1.1 1.4 1.4 1.1 1.2 1.0 1.1 1.1 1.2 1.3 2.0 1.1 1.3 2.7 1.2
Intensity Change (Log2) – – – 0.16 0.11 -0.15 -0.32 -0.14 -0.36 -0.33 -0.47 -0.34 0.18 0.18 0.14 0.41 0.55 0.39 0.07 0.24 0.16

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 3.4 3.9 3.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.3735 -0.8138 -0.9815 -1.1103 -1.3181 -0.7195 -0.0485 -0.2069 -0.6184 -1.2005 -0.7211 -0.3184 -0.6653 -1.1625 -1.4128 -1.0406 -1.8446 -1.0747
Actin 0.0163 0.0003 0.005 0.0007 0.0163 0.0032 0.0114 0.0017 0.0052 0.0006 0.0022 0.0042 0.0244 0.0004 0.0076 0.0057 0.0019 0.0051
Bud 0.0005 0.0014 0.0025 0.0002 0.0008 0.0001 0.0003 0.0012 0.0008 0.0006 0.0002 0.0004 0.0024 0.0007 0.0009 0.0204 0.0004 0.0028
Bud Neck 0.0037 0.0008 0.0017 0.0001 0.0016 0.0059 0.0017 0.0006 0.0009 0.0205 0.0009 0.0062 0.0166 0.0008 0.001 0.0009 0.0009 0.008
Bud Periphery 0.0011 0.0015 0.0034 0.0004 0.0028 0.0002 0.0004 0.0018 0.0007 0.001 0.0001 0.0012 0.0014 0.0005 0.0013 0.0022 0.0005 0.0013
Bud Site 0.0084 0.0061 0.0077 0.0001 0.0016 0.0002 0.0011 0.0018 0.0016 0.0017 0.0053 0.0003 0.0203 0.0154 0.0101 0.002 0.0003 0.0021
Cell Periphery 0.0004 0.0002 0.0002 0 0.0002 0 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0004 0.0001 0.0003 0.0001 0 0.0002
Cytoplasm 0.071 0.0552 0.0442 0.0602 0.0404 0.0764 0.0834 0.153 0.0919 0.095 0.1152 0.1103 0.1407 0.1187 0.1293 0.1122 0.1472 0.1498
Cytoplasmic Foci 0.0255 0.007 0.0048 0.0087 0.0023 0.0096 0.0201 0.0044 0.009 0.0186 0.0211 0.0066 0.02 0.0029 0.0147 0.0115 0.0096 0.01
Eisosomes 0.0005 0.0001 0.0002 0.0002 0.0004 0.0001 0.0002 0.0008 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0021 0.0011 0.0011 0.0006 0.0012 0.0013 0.0027 0.002 0.003 0.002 0.0014 0.0013 0.0039 0.0019 0.0033 0.001 0.0009 0.0016
Endosome 0.0147 0.0016 0.0026 0.0009 0.0014 0.004 0.0145 0.002 0.0043 0.0062 0.0082 0.0052 0.0211 0.0015 0.0066 0.0037 0.0041 0.006
Golgi 0.0047 0.0002 0.0007 0.0001 0.0005 0.0007 0.0042 0.0003 0.0011 0.0014 0.0014 0.001 0.0079 0.0001 0.0026 0.0059 0.0024 0.0008
Lipid Particles 0.0172 0.0021 0.0008 0.0006 0.0007 0.005 0.0285 0.001 0.0025 0.0024 0.0025 0.0014 0.0111 0.0002 0.0028 0.015 0.0029 0.0029
Mitochondria 0.0092 0.0025 0.0015 0.0004 0.0013 0.0008 0.0058 0.0013 0.0013 0.0013 0.0004 0.0023 0.0057 0.0006 0.0054 0.007 0.0274 0.0024
None 0.4883 0.6979 0.8381 0.9037 0.9073 0.5265 0.3703 0.5409 0.7216 0.7677 0.7565 0.3979 0.3267 0.4812 0.5943 0.6603 0.6786 0.3436
Nuclear Periphery 0.0089 0.0051 0.0066 0.003 0.0046 0.0072 0.0116 0.0071 0.0092 0.0053 0.0018 0.0062 0.0102 0.0109 0.009 0.0023 0.002 0.0068
Nucleolus 0.0039 0.004 0.0023 0.0005 0.0009 0.0045 0.0033 0.0033 0.0022 0.0043 0.0005 0.0039 0.0041 0.0028 0.0069 0.0018 0.0012 0.0042
Nucleus 0.2642 0.1929 0.0571 0.0074 0.009 0.2849 0.3886 0.2479 0.1184 0.0395 0.0644 0.4221 0.3617 0.3373 0.1779 0.0958 0.0768 0.4201
Peroxisomes 0.0266 0.0018 0.0022 0.0008 0.0005 0.0026 0.0195 0.0012 0.0076 0.0184 0.0024 0.0022 0.0075 0.0002 0.0064 0.0288 0.0015 0.0028
Punctate Nuclear 0.0295 0.0163 0.0156 0.011 0.0052 0.0661 0.0303 0.0247 0.0157 0.0081 0.0147 0.0255 0.0079 0.021 0.0157 0.0226 0.0401 0.0278
Vacuole 0.0027 0.0015 0.0012 0.0003 0.0005 0.0005 0.0012 0.0024 0.0021 0.0044 0.0006 0.0012 0.0049 0.0025 0.0032 0.0006 0.0007 0.0013
Vacuole Periphery 0.0006 0.0002 0.0004 0.0001 0.0003 0.0003 0.0007 0.0004 0.0005 0.0008 0.0001 0.0004 0.0009 0.0004 0.0007 0.0002 0.0005 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 32.3148 46.22 25.7229 36.2636 30.471 38.7563 45.4053 37.9933 42.6579 36.5469
Translational Efficiency 1.4648 1.3142 2.2614 1.7069 1.983 1.7487 1.2198 1.8165 1.3258 1.2433

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
470 888 1271 502 1932 1495 163 818 2402 2383 1434 1320

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 662.49 678.16 771.72 789.71 651.65 688.10 952.80 832.27 653.77 684.40 792.30 816.08
Standard Deviation 68.94 106.39 94.78 101.01 77.93 83.79 99.64 109.44 76.38 92.98 111.33 108.30
Intensity Change Log 2 — 0.033727 0.220179 0.253424 — 0.078521 0.548076 0.352954 — 0.056113 0.392076 0.303637

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000110 0.000526 0.000124 0.000305 0.000058 0.000234 0.003402 0.000551 0.000068 0.000343 0.000497 0.000457
Bud Neck 0.013549 0.033669 0.005753 0.003791 0.010467 0.025376 0.001765 0.005845 0.011070 0.028466 0.005300 0.005064
Bud Site 0.002033 0.018729 0.004358 0.006211 0.003867 0.007798 0.003193 0.026004 0.003508 0.011872 0.004225 0.018477
Cell Periphery 0.000220 0.000199 0.000460 0.000223 0.000231 0.000202 0.000261 0.000169 0.000229 0.000201 0.000438 0.000189
Cytoplasm 0.337596 0.329600 0.297072 0.285625 0.419133 0.375512 0.124079 0.361546 0.403179 0.358403 0.277408 0.332673
Cytoplasmic Foci 0.244375 0.218014 0.014316 0.022303 0.124340 0.199983 0.021129 0.024181 0.147827 0.206702 0.015090 0.023467
Eisosomes 0.000229 0.000166 0.000097 0.000063 0.000135 0.000152 0.000141 0.000050 0.000153 0.000157 0.000102 0.000055
Endoplasmic Reticulum 0.000728 0.001214 0.001689 0.007169 0.001300 0.000632 0.007271 0.003065 0.001188 0.000849 0.002323 0.004626
Endosome 0.008862 0.022203 0.001374 0.004635 0.004325 0.012967 0.005684 0.005870 0.005213 0.016409 0.001864 0.005400
Golgi 0.001485 0.004295 0.000066 0.001685 0.001139 0.004494 0.001257 0.003680 0.001207 0.004419 0.000201 0.002922
Lipid Particles 0.012947 0.008761 0.001080 0.003229 0.007739 0.007793 0.005000 0.001757 0.008758 0.008154 0.001526 0.002317
Mitochondria 0.004337 0.017385 0.000828 0.001191 0.005800 0.013101 0.000690 0.003920 0.005513 0.014697 0.000812 0.002882
Mitotic Spindle 0.000421 0.004655 0.003567 0.014334 0.001518 0.005508 0.006212 0.055664 0.001303 0.005190 0.003868 0.039946
None 0.004102 0.007500 0.010216 0.004428 0.004183 0.005951 0.002280 0.008032 0.004167 0.006528 0.009314 0.006662
Nuclear Periphery 0.000915 0.000901 0.001147 0.002333 0.000768 0.000509 0.002076 0.001858 0.000797 0.000655 0.001252 0.002039
Nuclear Periphery Foci 0.000336 0.000798 0.000314 0.002810 0.000305 0.000341 0.002102 0.001223 0.000311 0.000511 0.000517 0.001827
Nucleolus 0.001593 0.004570 0.001109 0.000926 0.001860 0.003008 0.001061 0.001394 0.001807 0.003590 0.001103 0.001216
Nucleus 0.324855 0.249822 0.635471 0.552858 0.384868 0.282812 0.693586 0.414314 0.373125 0.270518 0.642076 0.467002
Peroxisomes 0.011243 0.022707 0.000304 0.000487 0.002488 0.016168 0.001693 0.001219 0.004201 0.018605 0.000462 0.000940
Vacuole 0.029481 0.051802 0.020483 0.085005 0.024878 0.036175 0.114651 0.074135 0.025778 0.041998 0.031187 0.078269
Vacuole Periphery 0.000585 0.002484 0.000174 0.000388 0.000599 0.001286 0.002465 0.005524 0.000596 0.001732 0.000435 0.003571

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.11 -2.31 -8.01 2.15 -5.19 -7.35 -1.30 -7.69 -5.41 0.91 -8.10 -1.77 -9.37 -3.57 -0.85
Bud Neck -6.17 3.04 3.69 10.36 0.95 -7.84 10.99 0.75 8.08 -8.69 -10.66 4.45 3.13 12.80 -1.92
Bud Site -7.81 -2.72 -3.18 5.26 -0.84 -3.93 0.43 -5.05 -3.63 -4.99 -7.88 -1.09 -5.42 -0.85 -4.58
Cell Periphery 1.26 -5.71 2.18 1.28 6.83 1.33 -0.89 2.95 2.65 4.72 1.57 -4.63 3.20 2.87 8.21
Cytoplasm 0.62 4.03 6.21 6.35 3.26 4.80 21.80 15.07 10.23 -8.92 5.95 16.07 17.52 12.02 1.43
Cytoplasmic Foci 2.20 22.08 21.26 26.36 -2.49 -11.13 22.70 25.65 30.80 0.60 -9.98 34.31 32.41 40.44 -2.33
Eisosomes 2.71 6.50 7.50 6.57 1.84 -1.27 -2.24 3.18 5.19 5.34 -0.28 4.73 6.49 8.17 1.41
Endoplasmic Reticulum -3.28 -8.54 -10.22 -9.42 -7.74 1.66 -8.61 -9.26 -14.74 3.66 1.00 -5.59 -12.14 -16.83 -9.10
Endosome -5.96 6.54 3.76 9.22 -5.09 -7.45 -2.33 -2.36 5.41 0.24 -10.62 8.36 -0.19 10.17 -7.03
Golgi -4.96 4.52 0.87 4.06 -1.08 -4.72 0.77 -0.19 3.54 -0.67 -6.52 6.79 0.24 5.05 -2.08
Lipid Particles 2.36 7.53 6.39 6.10 -4.32 -0.08 2.72 8.39 6.10 5.10 0.75 12.73 10.49 8.47 -4.18
Mitochondria -5.16 3.80 3.71 7.03 -0.19 -3.40 4.45 3.20 6.16 -2.48 -5.30 4.86 4.06 9.14 -1.93
Mitotic Spindle -4.09 -2.81 -4.31 -3.49 -3.57 -2.96 -0.81 -7.92 -7.06 -6.99 -4.02 -2.17 -8.92 -7.82 -8.00
None -2.35 -3.27 0.23 3.02 3.94 -2.02 4.06 -3.23 -1.10 -5.69 -3.19 -3.56 -2.68 0.63 1.90
Nuclear Periphery 0.03 -1.92 -6.13 -6.81 -5.98 3.23 -8.27 -13.76 -15.09 -3.92 1.37 -7.96 -14.42 -15.07 -10.82
Nuclear Periphery Foci -2.33 -1.07 -5.19 -4.34 -5.09 -0.49 -6.72 -5.97 -5.93 -2.90 -2.30 -5.05 -7.63 -7.25 -7.01
Nucleolus -5.40 1.81 -0.23 4.72 -1.54 -2.09 3.08 -3.65 -2.37 -4.50 -4.10 2.49 -3.52 -0.98 -4.50
Nucleus 4.48 -20.34 -9.92 -15.53 7.58 10.32 -10.36 -2.68 -10.18 8.44 12.28 -27.63 -7.91 -17.44 15.75
Peroxisomes -4.39 6.41 6.29 11.11 -1.84 -9.91 2.13 2.24 10.33 -0.30 -12.03 9.77 6.79 15.04 -2.63
Vacuole -5.90 0.31 -12.79 -10.18 -13.01 -5.24 -8.84 -19.26 -17.65 -0.61 -8.57 -6.19 -23.28 -20.26 -18.56
Vacuole Periphery -5.49 5.15 3.57 6.56 -1.64 -4.21 -0.72 -1.29 -0.51 -0.15 -6.78 1.72 -1.05 0.94 -1.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p; function is regulated by phosphorylation at multiple sites and by phosphate availability
Localization
Cell Percentages cytoplasm (20%), nucleus (13%), mixed (43%)
Cell Cycle Regulation Yes
cytoplasm - MA (0.00066)
Subcompartmental Group N/A

Pho4

Pho4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pho4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available