Standard name
Human Ortholog
Description COPII-coated vesicle protein; involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p and Nha1p antiporter to cell surface; related to Drosophila cornichon; ERV14 has a paralog, ERV15, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.27 0.43 0.3 0.61 0.57 0.69 0.77 0.62 0.84 0.8 0.77 0.75 0.33 0.4 0.54 0.2 0.21 0.24 0 0 0 0 0 0
Endoplasmic Reticulum 0.05 0.08 0.08 0.06 0.08 0.08 0.06 0.12 0.06 0.08 0.07 0.1 0.35 0.35 0.25 0 0 0.05 0.12 0.16 0.21 0.16 0.15 0.17
Endosome 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05
Golgi 0.07 0 0.05 0 0 0 0 0 0 0 0 0 0.05 0 0 0.07 0.09 0.06 0 0 0 0 0 0.05
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.74 0.54 0.68 0.52 0.47 0.33 0.21 0.28 0.16 0.14 0.14 0.11 0.37 0.31 0.29 0.82 0.84 0.81 0.74 0.72 0.71 0.73 0.68 0.66
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 2 0 0 0 1 2 0 4 8 21 13 1 2 3 2 1 1 0 1 0 1 0 1
Bud 0 4 0 0 1 3 2 8 0 9 9 4 1 1 0 0 0 0 11 8 2 1 3 8
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 1 2 4 8 11 4 8 2 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 146 258 115 188 243 462 505 511 608 576 543 436 152 217 269 74 91 102 17 30 10 3 6 3
Endoplasmic Reticulum 28 51 29 19 36 52 41 100 41 58 51 58 160 187 125 11 17 20 72 119 90 43 44 60
Endosome 0 1 0 1 3 2 4 3 10 6 40 17 2 4 13 0 1 1 14 13 6 6 13 17
Golgi 37 16 21 4 2 1 0 1 3 3 3 5 22 17 17 26 38 27 6 5 4 8 12 16
Mitochondria 0 1 0 0 1 2 1 2 2 3 3 5 0 0 0 1 1 0 0 1 0 0 0 1
Nucleus 6 1 2 1 2 5 5 9 2 1 1 3 0 1 1 26 9 14 7 5 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 3 3 0 2 1 4 1 0 0 0 0 0 14 15 5 2 3 5
Nucleolus 3 0 0 0 0 1 0 1 0 3 9 8 0 0 0 0 0 1 2 1 0 1 1 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 1 4 0 0 1 0
Vac/Vac Membrane 401 325 260 159 201 221 140 228 113 104 96 64 169 168 147 298 360 345 437 536 303 202 195 237
Unique Cell Count 545 602 384 307 426 674 652 823 722 721 703 582 454 540 501 362 431 424 590 749 429 276 289 357
Labelled Cell Count 623 659 428 372 489 751 705 870 791 784 782 627 510 598 575 438 518 511 590 749 429 276 289 357


Endoplasmic Reticulum, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 28.6 30.2 22.0 20.8 17.6 15.1 14.1 14.1 15.0 14.4 14.3 14.3 29.0 25.3 21.8 28.5 28.9 28.0 34.4 33.4 34.6
Std Deviation (1e-4) 7.0 6.8 5.8 5.0 4.7 4.3 4.1 3.9 4.3 4.2 3.9 3.7 6.6 5.5 4.5 7.6 7.7 7.6 9.3 10.4 9.7
Intensity Change (Log2) – – – -0.08 -0.32 -0.54 -0.64 -0.64 -0.55 -0.6 -0.62 -0.62 0.4 0.2 -0.01 0.38 0.4 0.35 0.65 0.6 0.66


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 3.4 2.9 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 8.2 7.8 12.1 15.1 10.4 18.1 16.3 15.2 13.8 1.1 3.2 7.1 -3.0 -2.9 -1.9
Endoplasmic Reticulum -0.7 0.5 0.1 -0.8 2.4 -1.2 0.3 -0.2 1.3 9.6 9.6 6.8 -2.7 -2.2 -1.7
Endosome 0 0 0 0 0 0 0 4.8 3.4 0 0 3.2 0 0 0
Golgi -2.9 -4.3 -5.8 -6.0 -6.5 -5.5 -5.5 -5.4 -4.3 -0.4 -1.8 -1.5 1.0 1.8 0.5
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 4.8 1.9 2.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.3 -5.9 -11.0 -14.8 -13.2 -17.4 -17.9 -18.2 -18.3 -8.8 -11.0 -11.4 4.6 5.3 4.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 29.0377 28.7417 30.452 28.9982 30.6833 29.4367 32.9467 36.41 35.9562 33.3258 34.7014 35.2506 19.8286 29.4018 27.8903 23.2597 26.6541 26.3841
Actin 0 0.0001 0.0001 0 0 0 0.0001 0.0001 0.0001 0.0001 0 0 0.0697 0.0001 0 0.0113 0.0338 0.0085
Bud 0.0002 0.0004 0.0002 0.0004 0.0001 0.0001 0.0002 0.0002 0.0003 0.0002 0.0003 0.0002 0.0013 0.0003 0.0005 0.0004 0.0015 0.0006
Bud Neck 0.0003 0.0012 0.0006 0.0006 0.0002 0.0006 0.0003 0.0008 0.0006 0.0005 0.0007 0.0007 0.0055 0.0009 0.0005 0.0009 0.0015 0.0032
Bud Periphery 0.0005 0.0006 0.0008 0.0008 0.0001 0.0006 0.0008 0.0007 0.001 0.0008 0.0011 0.0008 0.0019 0.0009 0.0015 0.001 0.0056 0.0019
Bud Site 0.0003 0.001 0.0003 0.0002 0.0001 0.0001 0.0002 0.0004 0.0003 0.0002 0.0001 0.0001 0.012 0.0005 0.0005 0.0033 0.0009 0.0007
Cell Periphery 0.0461 0.0475 0.0385 0.0474 0.0017 0.021 0.0382 0.0466 0.0353 0.0173 0.0341 0.0137 0.0089 0.0596 0.0299 0.0461 0.0153 0.0217
Cytoplasm 0.0434 0.1256 0.0711 0.0207 0.0349 0.0408 0.031 0.0875 0.0526 0.018 0.0517 0.0413 0.0785 0.0399 0.0123 0.0123 0.0239 0.021
Cytoplasmic Foci 0.0017 0.0033 0.0041 0.0033 0.0075 0.0005 0.0015 0.0015 0.0021 0.0013 0.0021 0.0004 0.018 0.0018 0.0004 0.019 0.0023 0.0065
Eisosomes 0 0 0 0 0 0 0 0 0 0 0 0 0.0004 0 0 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.2225 0.1478 0.1861 0.1253 0.0712 0.21 0.1702 0.1063 0.1785 0.027 0.0859 0.1483 0.0452 0.0552 0.0931 0.025 0.0159 0.0537
Endosome 0.0205 0.016 0.0263 0.0834 0.1542 0.0242 0.0324 0.0192 0.0396 0.0358 0.0414 0.0199 0.0421 0.0223 0.0127 0.0186 0.0229 0.0373
Golgi 0.001 0.0006 0.0024 0.0037 0.0016 0.001 0.0035 0.0009 0.0024 0.003 0.0025 0.0005 0.0057 0.0024 0.0004 0.0058 0.0028 0.0042
Lipid Particles 0.0118 0.0038 0.0121 0.0107 0.0021 0.0018 0.0065 0.0061 0.0066 0.0028 0.0179 0.0017 0.0129 0.0053 0.0144 0.0482 0.0023 0.0125
Mitochondria 0.0004 0.0002 0.0003 0.0002 0.0001 0.0002 0.0007 0.0002 0.0007 0.0003 0.0003 0.0003 0.0022 0.0003 0.0006 0.0014 0.0017 0.0015
None 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.004 0.0001 0.0001 0.0021 0.0073 0.0003
Nuclear Periphery 0.054 0.0307 0.0388 0.021 0.0248 0.042 0.0742 0.0353 0.0499 0.0191 0.0337 0.0821 0.0859 0.0312 0.1031 0.1049 0.0249 0.1166
Nucleolus 0.0013 0.0013 0.0007 0.0002 0.0001 0.0002 0.0007 0.0011 0.0031 0.0005 0.0004 0.0005 0.0055 0.0026 0.006 0.0023 0.0013 0.0042
Nucleus 0.0119 0.0111 0.0042 0.0016 0.0023 0.0053 0.0107 0.0102 0.0066 0.0119 0.006 0.0103 0.0388 0.02 0.0136 0.0078 0.0088 0.0567
Peroxisomes 0 0.0001 0 0 0 0 0 0 0 0 0 0 0.0062 0 0 0.0319 0.0001 0.0019
Punctate Nuclear 0.0001 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0593 0.0002 0.0001 0.0248 0.0016 0.0023
Vacuole 0.5488 0.5886 0.577 0.6342 0.6383 0.6055 0.5486 0.6408 0.5593 0.7624 0.6562 0.5922 0.41 0.7086 0.6046 0.5313 0.6945 0.5242
Vacuole Periphery 0.0351 0.0198 0.036 0.046 0.0607 0.0459 0.0801 0.0418 0.0608 0.0988 0.0653 0.087 0.0861 0.0476 0.1056 0.1015 0.1311 0.1205

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 158.7632 89.8856 112.3351 143.1102 102.9217 89.916 130.3457 137.208 127.6547 143.0689
Translational Efficiency 1.3951 2.3103 1.6782 1.1088 1.6096 2.3461 1.9245 1.2766 1.2513 1.411

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1922 1511 209 122 1693 1541 629 1112 3615 3052 838 1234

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1300.28 2069.90 2113.79 2526.49 1825.07 1931.85 2640.16 2658.64 1546.05 2000.20 2508.88 2645.57
Standard Deviation 233.37 441.99 321.68 640.40 424.73 475.06 453.22 663.11 426.63 464.15 481.51 662.07
Intensity Change Log 2 — 0.670739 0.701010 0.958312 — 0.082031 0.532674 0.542737 — 0.356613 0.605109 0.730362

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000033 0.000060 0.000067 0.000111 0.000073 0.000618 0.000080 0.000225 0.000052 0.000342 0.000077 0.000214
Bud Neck 0.000588 0.000603 0.004463 0.003823 0.000496 0.000641 0.001095 0.002272 0.000545 0.000622 0.001935 0.002425
Bud Site 0.001651 0.000763 0.001321 0.003835 0.001351 0.001394 0.001276 0.006991 0.001511 0.001081 0.001287 0.006679
Cell Periphery 0.003088 0.012111 0.001633 0.028958 0.015726 0.010016 0.015858 0.025707 0.009007 0.011053 0.012310 0.026029
Cytoplasm 0.008357 0.001104 0.000433 0.001872 0.001773 0.002140 0.002603 0.012299 0.005274 0.001627 0.002062 0.011268
Cytoplasmic Foci 0.004212 0.000862 0.001131 0.001128 0.002249 0.001049 0.001782 0.006296 0.003293 0.000957 0.001620 0.005785
Eisosomes 0.000004 0.000015 0.000007 0.000032 0.000009 0.000014 0.000030 0.000046 0.000007 0.000014 0.000024 0.000045
Endoplasmic Reticulum 0.156057* 0.066790 0.019221 0.096741 0.076078 0.086196 0.425298* 0.193632* 0.118601* 0.076588 0.324021* 0.184053*
Endosome 0.015400 0.005551 0.012164 0.020115 0.008593 0.008720 0.023693 0.036821 0.012212 0.007151 0.020818 0.035170
Golgi 0.001790 0.003170 0.003289 0.010309 0.007807 0.003978 0.007744 0.041814 0.004608 0.003578 0.006633 0.038699
Lipid Particles 0.001169 0.001020 0.001800 0.037594 0.001988 0.001764 0.024431 0.095260 0.001552 0.001396 0.018787 0.089559
Mitochondria 0.000197 0.000237 0.000234 0.000185 0.000229 0.000287 0.000316 0.000569 0.000212 0.000262 0.000295 0.000531
Mitotic Spindle 0.000079 0.000162 0.000328 0.000467 0.000089 0.000305 0.000042 0.001075 0.000084 0.000234 0.000113 0.001015
None 0.000071 0.000045 0.000014 0.000078 0.000115 0.000111 0.000236 0.000434 0.000092 0.000078 0.000181 0.000398
Nuclear Periphery 0.001549 0.000702 0.020028 0.005899 0.000505 0.001689 0.003373 0.002284 0.001060 0.001200 0.007527 0.002642
Nuclear Periphery Foci 0.003937 0.002516 0.040180 0.029602 0.003481 0.005161 0.018116 0.027850 0.003723 0.003852 0.023619 0.028023
Nucleolus 0.000315 0.000264 0.000400 0.000105 0.000270 0.000388 0.000090 0.000189 0.000294 0.000327 0.000167 0.000181
Nucleus 0.000637 0.000143 0.000475 0.000246 0.000167 0.000751 0.000225 0.000281 0.000417 0.000450 0.000287 0.000278
Peroxisomes 0.000068 0.000022 0.000017 0.000010 0.000064 0.000075 0.000117 0.000228 0.000066 0.000049 0.000092 0.000207
Vacuole 0.751039* 0.826793* 0.775766* 0.714655* 0.800456* 0.785348* 0.450780* 0.510543* 0.774182* 0.805867* 0.531832* 0.530723*
Vacuole Periphery 0.049759 0.077066 0.117030* 0.044237 0.078478 0.089356 0.022813 0.035184 0.063209 0.083271 0.046311 0.036079

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.44 -2.59 -2.43 -1.67 -1.39 -1.01 -0.54 -4.05 0.70 -3.70 -1.07 -1.95 -5.03 0.41 -3.99
Bud Neck -0.18 -5.28 -5.14 -5.14 0.68 -2.23 -5.11 -9.12 -8.28 -5.12 -1.34 -6.67 -9.97 -9.68 -1.73
Bud Site 3.49 0.50 -1.46 -1.99 -1.57 -0.07 0.04 -6.15 -5.96 -6.31 1.48 0.52 -6.38 -6.85 -6.51
Cell Periphery -10.93 3.22 -3.83 -2.44 -4.05 4.78 -0.14 -5.41 -9.54 -5.09 -2.87 -3.31 -10.65 -9.38 -7.75
Cytoplasm 7.19 8.22 5.34 -1.10 -2.04 -0.57 -1.44 -5.72 -5.18 -5.27 5.16 4.98 -3.62 -5.74 -5.57
Cytoplasmic Foci 5.45 3.43 3.70 -0.52 0.05 2.41 0.32 -5.63 -8.15 -3.81 5.81 1.84 -3.89 -8.62 -4.36
Eisosomes -6.99 -1.75 -4.49 -2.60 -4.01 -2.11 -3.69 -12.85 -9.33 -2.41 -5.96 -4.12 -14.43 -10.38 -3.93
Endoplasmic Reticulum 16.09 24.37 3.11 -1.54 -4.04 -2.23 -23.78 -13.59 -12.17 14.10 11.30 -16.04 -7.95 -13.54 9.66
Endosome 8.76 1.69 -1.42 -4.39 -2.18 -0.14 -9.17 -16.67 -17.49 -6.19 6.73 -6.52 -14.87 -19.30 -7.78
Golgi -1.75 -2.40 -3.32 -2.71 -2.69 3.04 0.05 -11.58 -13.63 -11.68 1.43 -2.07 -13.47 -13.98 -12.32
Lipid Particles 0.73 -2.15 -3.60 -3.61 -3.53 0.54 -7.83 -19.37 -19.43 -12.51 0.69 -7.94 -19.67 -19.71 -14.10
Mitochondria -0.48 -0.49 -0.04 0.28 0.28 -0.35 -0.98 -2.39 -1.59 -2.02 -0.54 -1.55 -2.87 -2.10 -2.12
Mitotic Spindle -0.57 -1.78 -1.38 -1.05 -0.47 -0.80 0.95 -1.36 -0.97 -1.42 -0.97 -0.80 -1.43 -1.16 -1.37
None 1.26 3.26 -0.20 -0.64 -1.16 0.08 -1.58 -3.12 -3.14 -1.79 0.45 -1.69 -3.52 -3.66 -2.28
Nuclear Periphery 4.05 -4.87 -2.54 -3.02 3.32 -4.24 -7.94 -8.64 -1.85 2.76 -0.81 -6.44 -5.91 -5.09 4.70
Nuclear Periphery Foci 2.14 -5.41 -3.57 -3.76 1.01 -1.85 -7.20 -12.65 -11.17 -3.25 -0.24 -8.78 -13.04 -12.80 -1.39
Nucleolus 0.95 -0.63 3.78 6.78 2.27 -1.60 6.62 1.47 2.32 -1.80 -0.71 2.79 2.09 2.53 -0.17
Nucleus 4.10 0.53 2.56 -1.42 0.91 -1.01 -1.01 -2.68 0.80 0.12 -0.13 0.46 1.76 0.56 0.53
Peroxisomes 3.01 3.67 4.37 1.61 1.55 -0.19 -1.11 -3.05 -2.63 -2.59 0.60 -0.90 -3.63 -3.92 -3.09
Vacuole -11.13 -1.70 1.48 4.56 2.21 2.36 25.24 29.35 27.45 -3.74 -6.62 20.15 26.51 30.37 0.12
Vacuole Periphery -8.00 -6.99 0.98 5.07 6.55 -2.51 16.69 13.28 15.61 -5.75 -7.32 5.08 12.34 18.41 3.10
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description COPII-coated vesicle protein; involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p and Nha1p antiporter to cell surface; related to Drosophila cornichon; ERV14 has a paralog, ERV15, that arose from the whole genome duplication
Localization
Cell Percentages vacuole (18%), ER (11%), mixed (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Erv14

Erv14


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erv14-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available