Standard name
Human Ortholog
Description Putative kinase; suppressor of GTPase mutant; similar to bovine rhodopsin kinase; may have a role in intracellular sterol transport
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.07 0.1 0 0 0 0.06 0.06 0.06
Bud 0.06 0.06 0.07 0.08 0.05 0.06 0.13 0.13 0.11 0.08 0.07 0.11 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0.05 0.06 0.1 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0.08 0.09 0 0.08 0.1 0.09 0.11 0.09 0.09 0.11 0.08 0.06 0.07 0.09 0.12 0.06 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.08 0.11 0.32 0.15 0.3 0.27 0.11 0.11 0 0 0 0 0.23 0.42 0.38 0.31 0.32 0.27 0.29 0.41 0.33 0.27 0.28 0.28
Golgi 0.06 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.08 0.28 0.37 0.36 0.35 0.18 0.17 0.23 0.26 0.29
Mitochondria 0.86 0.73 0.3 0.62 0.38 0.54 0.59 0.48 0.75 0.76 0.78 0.74 0.66 0.42 0.37 0.13 0.18 0.14 0.09 0.14 0.21 0.16 0.13 0.12
Nucleus 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.05 0 0.1 0.12 0.25 0.19 0.21 0.15 0.09 0 0.05 0.08 0.12 0.19 0.15 0 0 0 0.18 0.1 0.14 0.2 0.21 0.19
SpindlePole 0.08 0.09 0.26 0.23 0.28 0.19 0.29 0.32 0.2 0.26 0.17 0.29 0.07 0.12 0.07 0.24 0.19 0.23 0 0.08 0 0 0 0
Vac/Vac Membrane 0.05 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0.08 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 2 5 2 0 0 4 3 1 2 0 0 7 2 3 16 13 16 2 10 5 14 23 22
Bud 4 13 12 5 10 16 42 36 32 26 18 20 7 7 10 1 0 6 0 2 1 1 1 2
Bud Neck 0 0 0 0 1 1 0 2 2 0 0 2 0 0 0 0 0 0 0 0 1 2 1 0
Bud Site 0 0 0 1 0 4 10 12 15 20 23 9 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 2 1 1 0 0 1 1 1 1 2 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 17 16 2 15 26 31 32 26 30 26 15 13 25 31 21 10 14 0 0 3 0 1 0
Endoplasmic Reticulum 2 9 2 1 0 0 0 1 0 0 0 0 10 4 8 7 3 3 0 0 2 1 3 2
Endosome 5 25 56 10 56 72 36 30 11 2 4 7 52 150 137 55 56 44 25 113 73 65 112 105
Golgi 4 4 6 0 3 0 0 1 0 0 0 0 13 22 28 51 64 59 30 49 37 55 107 110
Mitochondria 55 162 53 41 70 141 197 138 216 243 187 132 149 151 133 24 31 22 7 38 47 40 53 44
Nucleus 0 1 1 4 1 4 11 6 4 7 5 6 1 1 2 0 1 0 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 1 0 0 0 0 0 0
Nucleolus 5 8 0 2 0 1 3 10 8 12 7 5 1 4 7 3 2 2 0 1 0 0 0 0
Peroxisomes 3 5 18 8 47 51 69 42 27 7 13 15 28 68 56 3 3 1 15 26 30 48 84 72
SpindlePole 5 20 45 15 52 51 98 92 56 85 41 52 15 44 27 43 33 38 2 22 7 7 10 6
Vac/Vac Membrane 3 7 13 2 4 8 4 5 4 6 2 3 8 6 17 10 14 11 1 7 4 5 4 4
Unique Cell Count 64 223 174 66 186 263 334 285 287 321 240 178 227 357 362 179 175 162 88 276 219 246 408 375
Labelled Cell Count 92 273 228 93 261 376 506 410 402 442 327 267 306 486 459 234 230 217 88 276 219 246 408 375


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.0 5.2 6.3 5.5 6.4 5.4 5.2 5.6 4.6 4.4 4.2 4.5 5.8 5.9 6.2 8.8 9.5 8.3 5.4 5.6 5.9
Std Deviation (1e-4) 0.6 0.7 1.2 1.8 1.7 1.7 1.5 1.7 1.4 1.2 1.3 1.1 0.8 1.0 1.0 1.3 1.8 1.5 0.8 1.0 1.3
Intensity Change (Log2) – – – -0.19 0.02 -0.23 -0.29 -0.17 -0.46 -0.54 -0.59 -0.49 -0.12 -0.09 -0.03 0.48 0.59 0.39 -0.22 -0.18 -0.09

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0.1 0 0 2.4 1.9 2.6
Bud 0 -0.6 -0.3 2.0 1.9 0 0 0 0 -1.8 -2.9 -2.3 -3.2 -3.5 -1.3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 -0.4 0.2 0 0.7 0 0.1 0.5 -0.3 -1.3 -0.9 -0.2 0.8 -1.2 -0.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 1.9 0 0 0 0 0
Endosome -2.6 -0.4 -1.1 -5.9 -5.8 0 0 0 0 -2.1 2.2 1.3 -0.3 0 -1.0
Golgi 0 0 0 0 0 0 0 0 0 1.1 1.3 1.9 6.4 7.7 7.6
Mitochondria 4.5 1.4 4.8 6.1 3.8 0 0 0 0 7.0 2.6 1.4 -3.9 -2.8 -3.7
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.4 3.7 2.5 2.9 1.4 0 0 0 0 0.6 2.6 1.6 -3.4 -3.4 -3.9
SpindlePole -0.5 0.4 -1.6 0.8 1.5 0 0 0 0 -5.4 -3.9 -5.9 -0.4 -1.6 -0.5
Vacuole 0 -2.4 -2.1 -3.7 -3.1 -3.4 -3.1 -3.6 -2.6 -1.8 -3.4 -1.3 -0.7 0.2 -0.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.9655 3.5479 3.1167 2.7085 2.6308 3.0835 0.6708 1.1057 0.9923 1.0979 0.5124 0.9443 0.4008 1.2841 0.9543 0.8544 1.0257 0.9092
Actin 0.032 0.0191 0.0114 0.0018 0.0431 0.0168 0.0333 0.0364 0.0213 0.0031 0.0177 0.0105 0.0327 0.0171 0.0245 0.0042 0.063 0.0192
Bud 0.0003 0.001 0.0003 0.0001 0.0003 0.0002 0.0004 0.0009 0.0008 0.0008 0.0002 0.0001 0.0004 0.0002 0.0003 0.0003 0.0007 0.0002
Bud Neck 0.0015 0.0037 0.0017 0.001 0.0023 0.0022 0.0012 0.0008 0.0009 0.001 0.0004 0.001 0.001 0.0005 0.0013 0.001 0.0013 0.0009
Bud Periphery 0.0004 0.0014 0.0003 0.0001 0.0005 0.0005 0.0004 0.0006 0.0009 0.0012 0.0003 0.0001 0.0004 0.0001 0.0002 0.0002 0.0014 0.0003
Bud Site 0.0026 0.0241 0.0114 0.0005 0.0009 0.0009 0.002 0.0098 0.0065 0.003 0.0007 0.0004 0.003 0.0009 0.001 0.0008 0.0015 0.0004
Cell Periphery 0.0004 0.0012 0.0002 0.0001 0.0001 0.0002 0.0002 0.0001 0.0002 0.0002 0.0001 0 0.0002 0.0001 0 0.0001 0.0003 0.0001
Cytoplasm 0.0201 0.0125 0.0526 0.0033 0.0072 0.0105 0.013 0.0196 0.0086 0.0034 0.0026 0.0041 0.0167 0.0291 0.0049 0.0226 0.0037 0.0024
Cytoplasmic Foci 0.2254 0.2608 0.1791 0.2411 0.1741 0.1902 0.2195 0.2812 0.2069 0.1469 0.231 0.1992 0.2694 0.2487 0.2239 0.2205 0.1702 0.1879
Eisosomes 0.0016 0.0011 0.0002 0 0.0004 0.0002 0.0002 0.0001 0.0001 0 0.0002 0.0002 0.0002 0.0001 0.0001 0 0.0002 0.0002
Endoplasmic Reticulum 0.0032 0.0019 0.003 0.0002 0.0023 0.0004 0.0032 0.0013 0.0008 0.0008 0.0009 0.0003 0.0046 0.0036 0.0006 0.0012 0.0014 0.0011
Endosome 0.1856 0.2535 0.1843 0.2768 0.2555 0.1707 0.327 0.2453 0.2753 0.3878 0.3037 0.2547 0.2712 0.3463 0.2894 0.3406 0.3994 0.2307
Golgi 0.1152 0.1637 0.1528 0.121 0.162 0.1607 0.2 0.188 0.2334 0.2456 0.2494 0.3016 0.1455 0.2021 0.254 0.2273 0.1615 0.2874
Lipid Particles 0.1054 0.0337 0.0456 0.0687 0.0301 0.0933 0.0469 0.0196 0.0327 0.012 0.0374 0.0344 0.0708 0.0208 0.0335 0.0541 0.0946 0.076
Mitochondria 0.0564 0.0499 0.0516 0.0596 0.0237 0.0464 0.0208 0.0209 0.0338 0.0328 0.016 0.0192 0.007 0.0067 0.0103 0.009 0.0143 0.0383
None 0.0456 0.0226 0.0206 0.0008 0.0048 0.0102 0.0084 0.005 0.0019 0.0002 0.0023 0.0002 0.0249 0.0118 0.0142 0.0011 0.0009 0.0004
Nuclear Periphery 0.002 0.0006 0.0077 0.0001 0.0006 0.0005 0.0049 0.0004 0.0006 0.0004 0.0036 0.0001 0.0044 0.0007 0.0002 0.0004 0.0008 0.0006
Nucleolus 0.0016 0.0007 0.0011 0.0002 0.0002 0.0004 0.0003 0.0005 0.0004 0.0002 0.0006 0.0001 0.0003 0.0001 0.0001 0.0001 0.0005 0.0001
Nucleus 0.001 0.0006 0.0787 0.0001 0.0002 0.0075 0.0007 0.0003 0.0005 0.0004 0.0005 0.0001 0.0013 0.0005 0.0001 0.0002 0.0004 0.0001
Peroxisomes 0.1866 0.1409 0.1906 0.2202 0.2857 0.2795 0.1036 0.1592 0.163 0.1503 0.1258 0.171 0.1366 0.1051 0.1324 0.1093 0.0483 0.1492
Punctate Nuclear 0.0087 0.0011 0.0024 0.0015 0.0007 0.0056 0.0047 0.002 0.0007 0.0003 0.0029 0.0004 0.0043 0.0012 0.0056 0.0011 0.0022 0.001
Vacuole 0.0029 0.0047 0.0027 0.0016 0.0036 0.0021 0.0067 0.0069 0.0088 0.0063 0.0019 0.0012 0.0041 0.003 0.0023 0.0042 0.0302 0.0018
Vacuole Periphery 0.0013 0.0012 0.0016 0.0012 0.0016 0.0009 0.0025 0.001 0.0021 0.0032 0.002 0.0009 0.0013 0.0013 0.001 0.0019 0.0032 0.0019

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.8534 11.8447 7.2739 9.5232 7.1086 5.9364 13.7313 8.2225 6.9837 11.6839
Translational Efficiency 1.0447 0.7166 0.7162 0.436 0.7946 1.0496 0.6746 0.7591 0.779 0.6482

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1862 1864 1284 140 1931 1929 346 1105 3793 3793 1630 1245

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 728.81 840.60 1042.34 1057.88 810.87 835.49 1047.90 996.66 770.59 838.00 1043.52 1003.54
Standard Deviation 199.61 106.83 142.51 135.62 92.84 106.19 112.66 118.79 160.09 106.54 136.74 122.34
Intensity Change Log 2 — 0.205877 0.516211 0.537561 — 0.043152 0.369959 0.297631 — 0.122469 0.441038 0.416185

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000894 0.001238 0.028470 0.020085 0.001201 0.001463 0.006411 0.004914 0.001050 0.001352 0.023788 0.006620
Bud Neck 0.003476 0.000831 0.001086 0.003440 0.001565 0.001521 0.001681 0.001609 0.002503 0.001182 0.001212 0.001815
Bud Site 0.007374 0.004192 0.010339 0.056466 0.004077 0.003688 0.008318 0.015134 0.005695 0.003936 0.009910 0.019782
Cell Periphery 0.000097 0.000034 0.000073 0.000083 0.000047 0.000065 0.000045 0.000042 0.000072 0.000050 0.000067 0.000047
Cytoplasm 0.009681 0.005188 0.003106 0.014424 0.005486 0.004653 0.003300 0.009081 0.007545 0.004916 0.003147 0.009682
Cytoplasmic Foci 0.233547 0.293966 0.401773 0.328324 0.250678 0.248838 0.365627 0.303851 0.242269 0.271015 0.394100 0.306603
Eisosomes 0.000074 0.000035 0.000074 0.000055 0.000066 0.000063 0.000039 0.000032 0.000070 0.000050 0.000067 0.000034
Endoplasmic Reticulum 0.000143 0.000224 0.002236 0.000319 0.000160 0.000140 0.000816 0.000229 0.000152 0.000181 0.001934 0.000239
Endosome 0.149214 0.190388 0.153544 0.170154 0.157617 0.176329 0.217609 0.268075 0.153492 0.183238 0.167143 0.257064
Golgi 0.418121 0.399624 0.206381 0.142494 0.450156 0.443696 0.140011 0.201188 0.434430 0.422038 0.192292 0.194588
Lipid Particles 0.010251 0.005955 0.018831 0.004080 0.007712 0.009999 0.013995 0.003058 0.008958 0.008012 0.017804 0.003173
Mitochondria 0.070826 0.026585 0.003247 0.002462 0.050768 0.040724 0.001976 0.009755 0.060615 0.033776 0.002977 0.008935
Mitotic Spindle 0.011754 0.026304 0.119000 0.091314 0.014759 0.012280 0.123602 0.103814 0.013284 0.019172 0.119977 0.102409
None 0.000586 0.000064 0.000023 0.000020 0.000093 0.000073 0.000020 0.000631 0.000335 0.000069 0.000022 0.000563
Nuclear Periphery 0.000043 0.000039 0.000271 0.000083 0.000039 0.000056 0.000203 0.000185 0.000041 0.000048 0.000257 0.000173
Nuclear Periphery Foci 0.000222 0.000281 0.005165 0.001749 0.000306 0.000242 0.004657 0.000695 0.000265 0.000261 0.005057 0.000814
Nucleolus 0.000735 0.000334 0.000037 0.000072 0.000319 0.000329 0.000127 0.000113 0.000523 0.000331 0.000056 0.000108
Nucleus 0.001693 0.000336 0.000322 0.000139 0.000205 0.000336 0.000429 0.000136 0.000936 0.000336 0.000345 0.000136
Peroxisomes 0.074823 0.036217 0.026986 0.133264 0.046637 0.046906 0.090396 0.041614 0.060474 0.041653 0.040446 0.051920
Vacuole 0.003763 0.005205 0.016837 0.028963 0.004787 0.004752 0.019113 0.030946 0.004284 0.004975 0.017320 0.030723
Vacuole Periphery 0.002682 0.002960 0.002201 0.002010 0.003320 0.003843 0.001626 0.004899 0.003007 0.003409 0.002079 0.004574

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.09 -10.55 -3.04 -2.98 1.31 -1.08 -4.06 -4.24 -3.92 0.98 -1.52 -10.89 -5.28 -4.95 7.40
Bud Neck 6.61 5.95 -0.20 -2.64 -2.36 0.11 -0.32 -0.75 -0.80 -0.34 4.59 4.94 1.26 -2.80 -2.85
Bud Site 2.75 -2.55 -4.59 -4.89 -4.28 0.58 -3.55 -7.04 -7.37 -3.89 2.65 -4.89 -7.51 -8.56 -5.05
Cell Periphery 3.39 1.20 0.46 -3.49 -0.78 -1.84 0.13 0.96 2.44 0.65 2.10 0.33 2.48 0.47 4.34
Cytoplasm 3.33 5.35 -1.66 -3.25 -3.95 1.03 2.21 -3.41 -4.26 -4.95 3.34 5.66 -2.41 -4.81 -6.28
Cytoplasmic Foci -12.00 -24.11 -4.80 -1.53 4.01 0.44 -9.56 -7.47 -7.74 5.00 -8.29 -25.77 -10.08 -5.25 11.63
Eisosomes 5.25 -0.13 1.60 -2.78 2.10 0.51 4.82 7.32 6.52 1.64 4.41 0.53 7.49 4.48 8.56
Endoplasmic Reticulum -1.42 -7.24 -2.49 -1.48 6.23 0.60 -3.16 -1.38 -1.78 2.79 -0.90 -7.66 -2.16 -1.33 7.20
Endosome -7.40 -0.73 -1.30 1.67 -1.05 -3.48 -5.49 -14.73 -12.01 -4.05 -7.68 -2.98 -15.67 -10.95 -12.96
Golgi 2.38 28.27 17.16 16.17 4.15 0.80 31.91 31.63 30.97 -5.81 2.23 41.56 36.07 34.70 0.01
Lipid Particles 3.09 -4.68 3.45 0.80 7.74 -1.65 -2.28 4.37 5.36 3.92 1.00 -6.09 6.13 5.12 10.18
Mitochondria 11.51 19.36 19.38 12.20 0.66 2.84 17.48 13.11 11.38 -4.52 10.27 25.49 20.02 12.48 -3.83
Mitotic Spindle -6.31 -16.94 -5.14 -4.21 1.48 1.40 -8.66 -13.36 -13.77 1.19 -4.03 -18.87 -14.58 -13.53 1.80
None 2.70 2.90 2.91 3.66 0.56 1.02 3.90 -1.08 -1.12 -1.22 2.79 3.25 -0.53 -1.12 -1.21
Nuclear Periphery 0.25 -7.32 -1.41 -1.53 3.21 -0.65 -3.54 -2.06 -1.77 0.17 -0.40 -8.47 -2.15 -2.03 1.30
Nuclear Periphery Foci -0.84 -5.68 -1.38 -1.35 1.45 1.05 -2.55 -1.81 -2.96 2.34 0.54 -6.15 -2.59 -2.81 5.17
Nucleolus 1.28 2.16 2.01 1.42 -1.16 0.09 1.83 1.90 1.54 0.08 1.20 2.81 2.44 1.92 -1.34
Nucleus 1.84 1.71 2.10 0.78 0.94 -0.81 -0.86 0.90 1.12 1.04 1.60 1.29 2.20 1.43 1.35
Peroxisomes 9.70 12.02 -3.29 -5.53 -6.05 -0.08 -4.41 1.30 1.39 4.87 7.04 5.80 2.17 -2.68 -2.60
Vacuole -2.58 -10.49 -4.70 -4.48 -2.54 0.04 -4.84 -10.73 -10.72 -3.71 -1.77 -11.26 -11.83 -11.53 -5.80
Vacuole Periphery -0.91 1.62 1.20 1.64 0.37 -1.09 4.15 -2.36 -1.41 -4.94 -1.40 3.65 -2.76 -1.95 -4.42
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative kinase; suppressor of GTPase mutant; similar to bovine rhodopsin kinase; may have a role in intracellular sterol transport
Localization
Cell Percentages mitochondrion (13%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Scy1

Scy1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Scy1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available