Standard name
Human Ortholog
Description Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes; RMD9 has a paralog, YBR238C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.07 0.05 0.07 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0.1 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0.08 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0.1 0.39 0.22 0.26 0 0 – 0 0 0 0.06 0.3 0.53 0.41 0.48 0.45 0.36 0 0.09 0.05 0.1 0.15 0.11
Mitochondria 0.92 0.86 0.6 0.85 0.73 0.82 0.77 – 0.85 0.87 0.93 0.88 0.85 0.69 0.73 0.11 0.08 0.1 0.88 0.77 0.79 0.76 0.66 0.72
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.09 0.07 0 0 0.05 0.13 0.11 – 0.11 0.07 0.1 0.1 0.07 0.05 0 0 0.05 0 0 0 0 0 0 0
Nucleolus 0.06 0.06 0 0 0.06 0.09 0.09 – 0.08 0.07 0.07 0 0 0 0 0 0.07 0.05 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.07 0.07 0.07 0 0 0.06 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.12 0.07 0.18 0.05 0.09 0.06 0.08 – 0.07 0.07 0 0.05 0.08 0.11 0.14 0.12 0.2 0.17 0 0 0 0 0.06 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 5 6 4 6 2 0 – 4 2 1 3 0 4 1 14 10 11 2 5 6 3 5 5
Bud 2 0 1 2 1 4 6 – 6 4 6 8 1 0 0 7 3 8 0 0 1 1 2 1
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 – 2 0 9 1 0 0 0 1 0 3 – – – – – –
Cell Periphery 1 8 11 7 3 3 0 – 3 5 1 4 1 6 8 11 10 16 0 1 1 0 0 0
Cytoplasm 1 3 5 5 9 1 5 – 8 4 4 6 0 6 8 17 8 13 0 0 1 2 0 3
Endoplasmic Reticulum 2 0 3 1 1 2 4 – 9 5 5 3 3 2 1 3 4 9 0 0 1 0 1 0
Endosome 1 4 7 6 5 13 30 – 3 8 3 8 2 2 8 9 4 5 2 5 8 4 8 3
Golgi 2 21 104 45 73 10 13 – 9 12 4 23 36 92 80 96 83 60 5 19 15 19 42 29
Mitochondria 145 173 159 176 204 296 305 – 314 313 351 342 101 120 141 22 15 17 142 167 253 149 191 197
Nucleus 0 1 0 1 3 1 4 – 1 2 0 5 0 0 0 3 1 2 0 0 0 1 1 1
Nuclear Periphery 14 13 6 4 15 46 44 – 41 26 37 39 8 9 8 5 10 3 0 0 2 0 1 1
Nucleolus 9 12 7 9 18 32 36 – 30 27 25 17 3 4 2 9 12 9 0 0 0 0 1 0
Peroxisomes 0 2 11 4 5 6 10 – 2 5 0 5 3 1 2 14 13 12 5 9 18 3 9 9
SpindlePole 1 0 3 1 3 3 4 – 3 5 3 5 0 2 0 7 3 3 0 0 0 1 2 2
Vac/Vac Membrane 19 13 49 10 25 20 32 – 24 25 13 21 10 20 27 24 36 28 2 4 4 8 18 14
Unique Cell Count 158 200 266 206 280 359 398 369 361 379 388 119 175 194 202 184 167 162 218 320 198 289 274
Labelled Cell Count 197 255 372 275 371 440 493 459 443 462 490 168 268 286 242 212 199 162 218 320 198 289 274


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.8 13.9 12.1 11.2 11.5 9.8 9.8 – 8.6 8.9 7.6 8.3 11.3 11.4 11.4 13.8 14.1 13.2 11.3 12.1 12.4
Std Deviation (1e-4) 2.1 2.8 2.3 2.0 2.2 2.1 2.2 – 2.2 2.1 1.8 2.0 1.7 2.0 2.0 3.4 3.5 3.3 2.1 2.6 2.7
Intensity Change (Log2) – – – -0.11 -0.07 -0.31 -0.31 – -0.5 -0.44 -0.67 -0.54 -0.1 -0.09 -0.09 0.18 0.21 0.12 -0.1 -0.0 0.03


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 -0.1 0 0 – 0 0 0 0 0 0 0 2.5 1.8 2.3
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.4 -2.3 -2.8 0 – -2.8 -2.2 0 -2.6 0 -0.4 0 0.7 0.6 2.3
Cytoplasm 0 1.0 0 0 – 0.3 0 0 0 0 0 1.4 3.3 1.5 3.0
Endoplasmic Reticulum 0 0 0 0 – 1.2 0 0 0 0 0 0 0 0 0
Endosome 0.2 -0.7 0.7 2.7 – 0 -0.3 0 -0.5 0 0 0.9 1.1 0 0
Golgi -4.0 -3.3 -11.6 -11.9 – -11.9 -11.4 -12.7 -10.5 -1.7 2.8 0.5 1.8 1.3 -0.7
Mitochondria 6.1 3.2 6.3 4.6 – 7.2 7.7 10.1 8.4 4.9 1.9 2.9 -10.8 -11.1 -10.2
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 1.9 4.7 4.2 – 4.2 2.8 3.8 3.9 0 1.6 1.2 0 1.8 0
Nucleolus 1.0 2.1 3.2 3.3 – 2.9 2.6 2.3 1.2 0 0 0 1.1 2.0 1.5
Peroxisomes -1.3 -1.6 -1.9 -1.2 – -3.2 -2.2 0 -2.3 0 0 -2.0 1.3 1.4 1.4
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole -4.4 -3.2 -5.1 -4.0 – -4.6 -4.4 -6.4 -5.3 -2.5 -2.0 -1.3 -1.9 0.3 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.0517 7.7088 6.9925 6.2578 5.7319 7.1532 8.4726 8.0147 8.3385 7.4277 7.034 8.021 9.8721 10.0858 8.8815 7.4272 8.0315 9.5494
Actin 0.0164 0.0226 0.0095 0.0002 0.0001 0.0009 0.0151 0.0029 0.0065 0.0002 0.0119 0.0026 0.0195 0.0024 0.0032 0.0186 0.0849 0.0074
Bud 0.0003 0.0028 0.0006 0.0001 0 0 0.0003 0.0002 0.0001 0 0.0005 0.0001 0.0004 0.0005 0 0.0001 0.0008 0.0001
Bud Neck 0.0007 0.0003 0.0003 0.0001 0 0 0.0006 0 0.0001 0 0.0001 0.0003 0.0002 0.0004 0 0.0004 0.0008 0
Bud Periphery 0.0004 0.0035 0.0011 0.0014 0 0 0.0005 0.0004 0.0003 0 0.0014 0.0002 0.0007 0.0012 0.0001 0.0003 0.0018 0.0002
Bud Site 0.0018 0.0047 0.0062 0.0002 0 0 0.0014 0.0004 0.0006 0 0.0007 0.0006 0.0012 0.0032 0.0001 0.0008 0.0013 0.0002
Cell Periphery 0.0003 0.0005 0.0003 0.0002 0 0 0.0002 0.0001 0.0002 0 0.0003 0.0001 0.0001 0.0005 0 0.0002 0.0005 0.0001
Cytoplasm 0.0002 0.0001 0.0032 0 0 0 0.003 0 0.0001 0 0.0021 0.0001 0.0005 0 0.0004 0.001 0.0005 0.0001
Cytoplasmic Foci 0.0068 0.0024 0.0028 0.0028 0 0.0003 0.0084 0.001 0.0023 0.0001 0.008 0.0015 0.0031 0.0009 0.0075 0.0094 0.0098 0.0016
Eisosomes 0.0007 0.0005 0.0003 0.0001 0.0001 0.0001 0.0005 0.0002 0.0003 0.0001 0.0003 0.0001 0.0004 0.0002 0.0001 0.0028 0.0012 0.0005
Endoplasmic Reticulum 0.0002 0 0.0005 0.0004 0 0 0.0014 0 0.0004 0 0.0009 0.0002 0.0009 0.0001 0.0002 0.0005 0.0017 0.0006
Endosome 0.0051 0.0028 0.0044 0.002 0.0001 0.0006 0.0167 0.0022 0.0042 0.002 0.0127 0.0059 0.0095 0.0031 0.0033 0.0014 0.0141 0.0037
Golgi 0.0264 0.011 0.0118 0.0013 0.0003 0.0076 0.0157 0.0084 0.0093 0.0076 0.043 0.0096 0.0076 0.0052 0.018 0.0042 0.0209 0.0131
Lipid Particles 0.0304 0.0204 0.0132 0.017 0.0006 0.0033 0.021 0.0012 0.0064 0.0003 0.0057 0.0043 0.0165 0.0067 0.0036 0.0091 0.016 0.0112
Mitochondria 0.8555 0.9037 0.9237 0.9361 0.9975 0.9799 0.8891 0.9703 0.9501 0.9887 0.8757 0.9661 0.9158 0.9464 0.9561 0.8712 0.773 0.95
None 0.0019 0 0.0005 0.0001 0 0 0.0014 0 0.0003 0 0.0039 0.0001 0.0008 0 0.0007 0.0495 0.0024 0.0003
Nuclear Periphery 0.0012 0 0.0009 0.0003 0 0 0.0032 0 0.0006 0 0.0062 0.0002 0.0046 0.0001 0.0001 0.0009 0.004 0.0034
Nucleolus 0.0038 0.0008 0.0007 0.0287 0 0 0.0008 0.0001 0.0002 0 0.0006 0.0003 0.0005 0.0008 0 0.0008 0.045 0.0003
Nucleus 0.0013 0.0002 0.0005 0.0018 0 0 0.0015 0 0.0002 0 0.0034 0.0002 0.0014 0.0002 0 0.0006 0.0047 0.0004
Peroxisomes 0.0265 0.0195 0.007 0.0012 0.0009 0.0031 0.0096 0.0109 0.0121 0.0005 0.0141 0.0054 0.01 0.0109 0.0036 0.0249 0.0043 0.0038
Punctate Nuclear 0.0006 0 0.0005 0.0013 0 0 0.0017 0 0.0003 0 0.0032 0.0003 0.0016 0 0.0009 0.0023 0.0018 0.0003
Vacuole 0.0019 0.0017 0.0059 0.0012 0 0.0004 0.0026 0.0004 0.002 0.0001 0.0023 0.0005 0.0011 0.0059 0.0003 0.0004 0.0024 0.0008
Vacuole Periphery 0.0176 0.0023 0.0061 0.0035 0.0003 0.0035 0.0053 0.0012 0.0035 0.0003 0.0033 0.0014 0.0035 0.011 0.0016 0.0006 0.0079 0.0023

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.6019 19.3108 19.9858 23.7996 18.4262 26.1352 23.2503 25.4893 25.0717 24.6618
Translational Efficiency 0.8055 0.8193 0.7887 0.7559 0.7756 0.7288 0.9437 0.8213 0.8227 0.8618

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
139 1361 149 1626 2155 1945 1857 106 2294 3306 2006 1732

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 855.89 1118.40 1505.52 1333.59 1061.71 1098.39 1300.16 1454.34 1049.24 1106.63 1315.41 1340.98
Standard Deviation 138.58 207.04 219.07 202.56 188.28 200.00 199.71 206.12 192.03 203.17 208.29 204.84
Intensity Change Log 2 — 0.385939 0.814765 0.639818 — 0.049001 0.292299 0.453975 — 0.209170 0.549049 0.539893

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001366 0.002602 0.009250 0.004567 0.000954 0.002612 0.002566 0.009704 0.000979 0.002608 0.003062 0.004882
Bud Neck 0.003001 0.001128 0.012867 0.002077 0.000446 0.000573 0.001178 0.006301 0.000601 0.000802 0.002046 0.002335
Bud Site 0.004096 0.003052 0.006680 0.005354 0.000864 0.000723 0.001873 0.005694 0.001060 0.001681 0.002230 0.005375
Cell Periphery 0.000165 0.000158 0.000195 0.000169 0.000082 0.000117 0.000077 0.000220 0.000087 0.000134 0.000086 0.000172
Cytoplasm 0.001336 0.000421 0.000831 0.001134 0.000480 0.000517 0.000458 0.000530 0.000532 0.000478 0.000486 0.001097
Cytoplasmic Foci 0.008298 0.014439 0.064612 0.008976 0.008199 0.012142 0.011172 0.016942 0.008205 0.013088 0.015141 0.009463
Eisosomes 0.000055 0.000238 0.000235 0.000158 0.000122 0.000124 0.000156 0.000416 0.000118 0.000171 0.000162 0.000174
Endoplasmic Reticulum 0.000254 0.000135 0.000638 0.000195 0.000063 0.000118 0.000117 0.000261 0.000075 0.000125 0.000156 0.000199
Endosome 0.009113 0.009313 0.031206 0.007318 0.005667 0.008687 0.005934 0.009437 0.005875 0.008945 0.007811 0.007448
Golgi 0.008614 0.028145 0.055967 0.034220 0.011826 0.026219 0.023585 0.032251 0.011631 0.027012 0.025990 0.034099
Lipid Particles 0.006627 0.006457 0.010146 0.002329 0.004509 0.003285 0.002277 0.002118 0.004638 0.004590 0.002861 0.002316
Mitochondria 0.917354* 0.900960* 0.694651* 0.902718* 0.947653* 0.927505* 0.919404* 0.851092* 0.945817* 0.916577* 0.902710* 0.899558*
Mitotic Spindle 0.004082 0.001818 0.033214 0.003620 0.000885 0.001045 0.005377 0.014335 0.001079 0.001363 0.007445 0.004275
None 0.000669 0.000692 0.001123 0.000773 0.000595 0.000660 0.000724 0.001113 0.000600 0.000673 0.000753 0.000794
Nuclear Periphery 0.000255 0.000093 0.005254 0.000230 0.000161 0.000113 0.000731 0.000368 0.000167 0.000104 0.001067 0.000239
Nuclear Periphery Foci 0.000386 0.000143 0.002742 0.000250 0.000192 0.000144 0.000357 0.000276 0.000204 0.000144 0.000534 0.000251
Nucleolus 0.000225 0.000203 0.001052 0.000211 0.000159 0.000112 0.000270 0.000418 0.000163 0.000150 0.000329 0.000224
Nucleus 0.004493 0.000098 0.000379 0.000071 0.000039 0.000051 0.000099 0.000108 0.000308 0.000071 0.000120 0.000073
Peroxisomes 0.019332 0.024194 0.023204 0.009399 0.011137 0.008251 0.011278 0.028992 0.011634 0.014814 0.012164 0.010598
Vacuole 0.004095 0.003241 0.026203 0.007185 0.002748 0.003232 0.004500 0.011369 0.002830 0.003235 0.006112 0.007441
Vacuole Periphery 0.006181 0.002471 0.019550 0.009048 0.003218 0.003770 0.007867 0.008054 0.003397 0.003235 0.008735 0.008987

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.95 -2.93 -3.33 -2.28 1.69 -3.19 -4.15 -2.25 -1.81 -1.83 -4.50 -5.04 -4.84 -2.69 -2.10
Bud Neck 0.86 -2.95 0.41 -2.16 4.12 -1.06 -3.52 -3.11 -3.04 -2.69 -1.17 -4.69 -4.00 -3.70 -0.54
Bud Site 0.44 -0.99 -0.55 -1.49 0.65 0.32 -1.84 -2.16 -2.25 -1.69 -1.05 -2.17 -3.76 -3.15 -2.70
Cell Periphery 0.10 -0.60 -0.09 -0.22 1.00 -0.67 0.12 -2.36 -1.59 -2.86 -1.05 0.01 -2.46 -1.06 -4.46
Cytoplasm 0.92 0.49 0.10 -1.45 -0.65 -0.10 0.09 -0.09 0.03 -0.44 0.15 0.16 -1.03 -1.28 -1.32
Cytoplasmic Foci -2.05 -5.73 -0.23 3.94 5.88 -3.06 -2.52 -1.59 -0.87 -1.05 -4.59 -5.13 -1.15 3.22 4.06
Eisosomes -9.61 -5.49 -6.39 3.71 2.26 -0.16 -1.18 -2.45 -2.43 -2.11 -4.66 -1.64 -3.37 -0.16 -0.39
Endoplasmic Reticulum 1.26 -2.57 0.63 -1.73 3.64 -2.70 -3.71 -2.12 -1.49 -1.53 -2.88 -4.68 -5.01 -2.67 -1.61
Endosome -0.06 -3.45 0.50 1.48 4.32 -2.64 -0.32 -1.19 -0.24 -1.11 -3.09 -1.93 -1.43 1.38 0.34
Golgi -5.30 -5.31 -6.70 -1.70 2.45 -6.32 -5.23 -1.83 -0.53 -0.77 -8.26 -6.54 -8.14 -2.37 -2.53
Lipid Particles 0.05 -0.86 1.24 3.79 3.56 1.52 3.06 2.11 1.15 0.17 0.05 2.43 2.89 3.44 0.98
Mitochondria 0.86 6.68 0.79 -0.16 -7.28 3.78 5.09 3.73 2.94 2.61 6.07 7.39 7.36 2.72 0.46
Mitotic Spindle 1.30 -4.19 0.18 -1.92 4.32 -0.36 -4.17 -1.59 -1.57 -1.04 -0.64 -5.61 -3.43 -3.20 2.20
None -0.16 -2.93 -0.83 -0.89 3.41 -0.82 -2.85 -2.82 -2.31 -2.11 -1.19 -3.56 -4.44 -1.84 -0.85
Nuclear Periphery 1.79 -2.24 0.24 -3.70 2.25 1.35 -3.96 -1.79 -2.30 2.04 1.86 -4.20 -1.55 -3.83 3.85
Nuclear Periphery Foci 1.21 -3.60 0.61 -1.49 3.97 1.06 -2.22 -0.95 -1.55 0.86 1.48 -3.84 -0.70 -1.61 2.71
Nucleolus 0.22 -2.33 0.13 -0.10 2.39 0.98 -1.26 -1.65 -1.98 -0.75 0.25 -1.86 -0.95 -1.23 1.11
Nucleus 1.02 0.95 1.02 0.67 2.32 -0.67 -1.49 -2.24 -1.60 -0.15 0.90 0.71 0.89 -0.10 1.05
Peroxisomes -0.64 -0.41 1.35 5.22 2.18 1.78 -0.08 -1.95 -2.27 -1.92 -1.86 -0.29 0.53 2.22 0.76
Vacuole 0.58 -3.83 -1.97 -3.73 3.34 -0.82 -2.52 -2.16 -2.04 -1.71 -0.75 -4.19 -4.80 -4.55 -1.24
Vacuole Periphery 1.98 -3.64 -1.41 -6.99 3.18 -0.92 -5.15 -1.38 -1.23 -0.05 0.29 -6.05 -5.65 -6.49 -0.23
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes; RMD9 has a paralog, YBR238C, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Rmd9

Rmd9


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rmd9-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available