ORF
Human Ortholog
Description Protein of unknown function, predicted to be palmitoylated; SWAT-GFP, seamless-GFP and mCherry C-terminal fusion proteins localize to the cytosol, while N-terminal GFP fusion protein localizes to the cell periphery; protein abundance increases in response to DNA replication stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.24 0.2 0.24 0.1 0.13 0.09 – 0.06 0.05 0.08 0.05 0.06 0.13 0.15 0.08 0.08 0.1 0.08 0 0 0 0 0 0
Bud 0 0 0.08 0 0.05 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.76 0.8 0.69 0.64 0.53 0.59 – 0.35 0.4 0.42 0.38 0.38 0.77 0.73 0.74 0.82 0.79 0.7 0.8 0.84 0.87 0.88 0.83 0.82
Cytoplasm 0.36 0.24 0.25 0.23 0.34 0.3 – 0.4 0.35 0.35 0.36 0.28 0.33 0.36 0.4 0.18 0.2 0.27 0.06 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0.05 – 0 0 0 0 0 0 0 0 0.09 0 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0.27 0.48 0.73 0.45 0.55 – 0.62 0.67 0.69 0.69 0.72 0.15 0.25 0.16 0.1 0.13 0.12 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.06 0.08 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 29 61 39 15 20 20 – 24 12 17 15 20 28 41 24 21 16 11 2 6 2 4 13 9
Bud 2 4 13 3 8 2 – 7 7 5 10 5 7 7 1 1 3 0 0 3 0 0 2 2
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 5 9 6 3 5 8
Bud Site 1 0 1 1 1 0 – 0 0 0 0 1 0 0 0 0 0 1 – – – – – –
Cell Periphery 91 241 113 94 80 126 – 128 90 95 110 135 168 200 217 203 130 93 109 297 156 169 286 276
Cytoplasm 43 74 41 34 51 64 – 149 78 79 102 102 72 99 118 45 33 36 8 12 1 4 13 13
Endoplasmic Reticulum 3 2 2 2 2 10 – 7 8 5 5 8 4 1 5 22 7 12 1 4 1 1 8 5
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 2 1 3 1 0 2 1
Golgi 0 1 0 0 0 0 – 0 0 0 0 1 0 1 1 2 4 2 0 2 0 1 1 0
Mitochondria 9 83 78 107 68 118 – 230 150 155 197 257 32 68 46 26 22 16 2 6 4 4 3 5
Nucleus 0 1 0 1 0 0 – 0 0 0 1 1 0 1 0 4 2 1 0 0 0 0 0 0
Nuclear Periphery 0 1 1 0 0 0 – 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 1 0 1 1 1 1 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 2 0 2 1 4 – 2 3 1 1 0 11 17 23 5 0 0 0 0 0 0 0 0
SpindlePole 0 1 0 1 0 0 – 1 0 0 0 2 2 4 1 1 0 3 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 1 0 0 – 9 1 2 4 6 1 2 2 6 3 2 0 4 1 1 2 2
Unique Cell Count 119 303 164 147 151 214 370 223 224 287 358 218 275 295 248 164 132 137 355 179 193 344 336
Labelled Cell Count 178 471 288 261 231 344 558 349 360 448 539 326 441 440 336 220 179 137 355 179 193 344 336


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 7.2 5.2 5.9 6.4 5.3 – 5.4 5.1 5.0 4.9 4.9 7.5 7.6 7.5 9.8 9.5 9.2 7.7 8.0 8.2
Std Deviation (1e-4) 0.7 0.8 1.1 1.5 1.5 0.8 – 1.1 1.4 1.0 1.2 1.2 1.6 1.9 1.9 2.0 1.8 1.9 1.4 2.1 2.1
Intensity Change (Log2) – – – 0.19 0.31 0.03 – 0.06 -0.04 -0.05 -0.08 -0.09 0.53 0.55 0.53 0.91 0.86 0.82 0.57 0.62 0.66


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.2 -2.4 -3.8 – -5.7 -5.3 -4.5 -5.8 0 -2.8 -2.3 -4.7 -4.3 -3.4 -3.5
Bud -2.3 -0.9 -3.5 – -3.4 -2.1 -2.6 -2.1 0 -2.0 -2.6 -4.5 -4.1 -2.6 -3.3
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.9 -2.9 -2.0 – -7.3 -5.6 -5.2 -6.2 0 1.8 0.9 1.1 3.0 2.1 0.3
Cytoplasm -0.4 1.7 1.1 – 3.4 2.1 2.2 2.3 0.8 1.7 2.4 3.2 -1.7 -1.1 0.4
Endoplasmic Reticulum 0 0 1.9 – 0 0 0 0 0 0 0 0 3.2 0 3.2
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.5 -0.4 1.5 – 3.2 3.9 4.3 4.4 0 -7.0 -4.9 -7.4 -8.5 -6.7 -6.5
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 3.2 3.7 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.601 2.5362 2.1989 1.9228 1.6144 2.1725 1.8945 2.3733 2.2214 1.9073 1.3124 2.1288 3.5218 4.0714 3.7965 3.5088 4.8812 3.5764
Actin 0.0498 0.0015 0.0223 0.0003 0.0046 0.0021 0.05 0.0022 0.022 0.0372 0.0079 0.0079 0.0459 0.0011 0.0027 0.0132 0.0062 0.0157
Bud 0.0011 0.0001 0.0006 0.0003 0.0006 0.0005 0.0045 0.0003 0.0048 0.0013 0.0007 0.0007 0.0023 0.0004 0.0009 0.0004 0.0021 0.0012
Bud Neck 0.0084 0.005 0.0065 0.0572 0.0077 0.0132 0.0092 0.0038 0.0084 0.0124 0.0203 0.0149 0.0161 0.0033 0.0099 0.0171 0.0034 0.0134
Bud Periphery 0.0063 0.0009 0.0042 0.0029 0.0066 0.0081 0.0242 0.0019 0.0081 0.0102 0.0043 0.0095 0.018 0.0025 0.0046 0.0026 0.0102 0.0085
Bud Site 0.0237 0.0615 0.0298 0.0119 0.0083 0.0022 0.0212 0.1069 0.0808 0.0153 0.0359 0.0043 0.0281 0.1089 0.0571 0.0193 0.0048 0.0042
Cell Periphery 0.5446 0.6683 0.6546 0.701 0.7087 0.7832 0.5048 0.5699 0.5664 0.6522 0.7193 0.6925 0.5877 0.552 0.6046 0.6052 0.6661 0.6617
Cytoplasm 0.1696 0.241 0.2079 0.2147 0.1506 0.1703 0.2432 0.2987 0.2433 0.1744 0.137 0.2285 0.1493 0.3174 0.2544 0.2267 0.1229 0.2343
Cytoplasmic Foci 0.0304 0.0008 0.0028 0.002 0.0061 0.0009 0.0123 0.0004 0.0079 0.0047 0.0005 0.0016 0.043 0.0004 0.0057 0.0096 0.0203 0.0019
Eisosomes 0.0164 0.002 0.0048 0.0002 0.0004 0.0006 0.0034 0.0027 0.0053 0.0053 0.0011 0.0015 0.0025 0.0007 0.0023 0.0001 0.0008 0.0002
Endoplasmic Reticulum 0.0036 0.0017 0.0047 0.0023 0.0057 0.0022 0.0138 0.0013 0.0027 0.0048 0.0014 0.0034 0.0037 0.001 0.002 0.0016 0.0021 0.0023
Endosome 0.0152 0 0.0107 0.0005 0.0366 0.0001 0.0198 0 0.0115 0.0158 0.0001 0.0034 0.0184 0 0.0012 0.0008 0.072 0.0118
Golgi 0.0086 0.0001 0.0178 0.0004 0.0025 0.0002 0.0057 0.0001 0.0047 0.0157 0.0003 0.0012 0.009 0.0001 0.0006 0.0027 0.039 0.0138
Lipid Particles 0.0153 0.0004 0.0029 0.0004 0.0095 0.001 0.0074 0.0002 0.0038 0.0036 0.0006 0.0024 0.0212 0.0002 0.0009 0.0021 0.0235 0.0067
Mitochondria 0.0149 0 0.0074 0.0001 0.001 0.0001 0.003 0 0.0013 0.0346 0 0.0004 0.0039 0 0.0001 0.0014 0.0059 0.0137
None 0.0516 0.0152 0.0161 0.0018 0.0082 0.012 0.0275 0.0099 0.014 0.0042 0.0681 0.0162 0.0083 0.0099 0.0459 0.0004 0.009 0.0031
Nuclear Periphery 0.0021 0.0001 0.0023 0.0001 0.0159 0.0001 0.0155 0.0001 0.001 0.0006 0.0001 0.0037 0.0069 0.0001 0.0002 0.0001 0.0005 0.0004
Nucleolus 0.0009 0.0001 0.0002 0.0012 0.0011 0.0002 0.0016 0.0001 0.0013 0.0003 0.0002 0.0004 0.0008 0.0001 0.0002 0 0.0002 0.0002
Nucleus 0.001 0.0001 0.0005 0.0004 0.004 0.0002 0.0083 0.0002 0.0035 0.0004 0.0002 0.0008 0.0017 0.0002 0.0004 0.0002 0.0003 0.0004
Peroxisomes 0.024 0.0001 0.0008 0.0003 0.0009 0 0.008 0 0.003 0.0028 0 0.0003 0.0177 0 0.0014 0.094 0.0031 0.0012
Punctate Nuclear 0.006 0 0.0003 0.0001 0.0108 0.0001 0.0075 0 0.001 0.0005 0.0001 0.002 0.0076 0 0.0015 0.0007 0.0004 0.0004
Vacuole 0.0059 0.0009 0.0024 0.002 0.0091 0.0029 0.0077 0.0012 0.0047 0.0032 0.0018 0.0043 0.0067 0.0015 0.0035 0.0019 0.0058 0.0045
Vacuole Periphery 0.0006 0 0.0004 0 0.0009 0 0.0013 0 0.0004 0.0007 0 0.0002 0.0008 0 0 0 0.0011 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.7383 6.9956 15.5731 15.5844 13.5282 23.4637 14.1464 15.9132 19.5204 13.8682
Translational Efficiency 1.4611 2.1618 1.3101 1.4016 1.5663 0.7548 1.1623 1.9978 1.4121 1.3933

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1616 1432 82 474 581 1627 2082 1619 2197 3059 2164 2093

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 721.60 873.30 1162.03 999.90 652.69 856.09 984.80 982.42 703.38 864.15 991.52 986.38
Standard Deviation 108.58 114.53 118.13 139.86 100.93 106.14 113.73 126.99 110.86 110.48 118.82 130.22
Intensity Change Log 2 — 0.275278 0.687376 0.470584 — 0.391365 0.593433 0.589942 — 0.331577 0.643521 0.528503

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003605 0.006356 0.036064 0.041195 0.004088 0.009748 0.020625 0.034738 0.003733 0.008160 0.021210 0.036200
Bud Neck 0.060315 0.025557 0.021753 0.033418 0.045039 0.067670 0.049286 0.039712 0.056275 0.047956 0.048242 0.038287
Bud Site 0.076369 0.081676 0.141166* 0.192159* 0.117197* 0.054724 0.096383 0.158276* 0.087166 0.067341 0.098080 0.165949*
Cell Periphery 0.229398* 0.390646* 0.377776* 0.245512* 0.438882* 0.129115* 0.209694* 0.311952* 0.284797* 0.251545* 0.216063* 0.296905*
Cytoplasm 0.536743* 0.453434* 0.192864* 0.294504* 0.301391* 0.614083* 0.428908* 0.335438* 0.474504* 0.538879* 0.419964* 0.326168*
Cytoplasmic Foci 0.025017 0.006659 0.030552 0.018769 0.014667 0.023835 0.011646 0.006779 0.022280 0.015795 0.012363 0.009495
Eisosomes 0.007602 0.006990 0.019345 0.025338 0.004100 0.028793 0.043264 0.029695 0.006676 0.018587 0.042357 0.028708
Endoplasmic Reticulum 0.004189 0.006119 0.051563 0.008947 0.013896 0.004175 0.017233 0.006428 0.006756 0.005085 0.018534 0.006998
Endosome 0.007113 0.001412 0.004735 0.003063 0.004372 0.004313 0.000920 0.003914 0.006388 0.002955 0.001064 0.003722
Golgi 0.005351 0.002953 0.007380 0.002742 0.002823 0.008571 0.001589 0.004485 0.004682 0.005941 0.001809 0.004090
Lipid Particles 0.008131 0.001634 0.007796 0.002346 0.003677 0.006759 0.002960 0.001355 0.006953 0.004360 0.003143 0.001579
Mitochondria 0.004617 0.003734 0.000270 0.000539 0.023289 0.004310 0.000570 0.003672 0.009555 0.004040 0.000559 0.002963
Mitotic Spindle 0.000081 0.000918 0.000265 0.006496 0.000092 0.000139 0.000227 0.002443 0.000084 0.000504 0.000228 0.003361
None 0.002824 0.000106 0.000043 0.000150 0.000714 0.000472 0.000539 0.000158 0.002266 0.000300 0.000521 0.000156
Nuclear Periphery 0.000111 0.000086 0.000169 0.000136 0.000153 0.000075 0.000153 0.000102 0.000122 0.000080 0.000154 0.000110
Nuclear Periphery Foci 0.000401 0.000223 0.004728 0.001173 0.001407 0.000270 0.001268 0.000590 0.000667 0.000248 0.001399 0.000722
Nucleolus 0.000255 0.000052 0.000050 0.000095 0.000325 0.000110 0.000057 0.000038 0.000274 0.000082 0.000057 0.000051
Nucleus 0.006215 0.001794 0.016320 0.016835 0.009043 0.010990 0.055977 0.015468 0.006963 0.006685 0.054474 0.015777
Peroxisomes 0.004287 0.003656 0.001241 0.001153 0.003484 0.007138 0.001114 0.001303 0.004075 0.005508 0.001119 0.001269
Vacuole 0.016362 0.005300 0.085733 0.103175 0.007835 0.024139 0.057513 0.041966 0.014107 0.015320 0.058583 0.055828
Vacuole Periphery 0.001014 0.000696 0.000188 0.002257 0.003528 0.000571 0.000073 0.001490 0.001679 0.000629 0.000077 0.001663

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.11 -4.43 -11.13 -10.20 -0.56 -4.71 -11.78 -15.91 -14.08 -7.38 -8.47 -16.87 -21.39 -18.12 -8.34
Bud Neck 11.08 9.08 6.83 -1.98 -2.37 -4.90 -0.97 1.34 8.78 3.78 2.98 2.86 6.91 4.50 4.31
Bud Site -1.03 -3.31 -10.65 -9.87 -2.18 8.20 2.64 -4.63 -17.99 -10.16 5.11 -2.47 -14.07 -18.89 -11.98
Cell Periphery -14.65 -4.00 -0.51 9.68 3.61 19.15* 14.28 7.52 -19.83 -11.22 3.76 8.15 -0.90 -4.92 -9.48
Cytoplasm 8.10 15.42 17.63 11.20 -4.27 -24.70 -10.28 -2.70 32.30 11.25 -8.09 6.74 17.47 28.31 12.16
Cytoplasmic Foci 9.75 -1.02 1.88 -5.22 1.87 -2.90 1.36 3.29 9.78 4.77 3.97 6.22 7.84 4.91 2.62
Eisosomes 0.91 -4.35 -8.45 -8.72 -1.65 -19.91 -30.84 -18.52 -0.42 7.48 -15.20 -28.85 -18.51 -7.42 8.42
Endoplasmic Reticulum -1.99 -4.40 -4.64 -2.18 3.96 4.73 -1.49 3.67 -2.42 8.37 2.03 -8.91 -0.27 -2.50 9.03
Endosome 8.19 2.23 3.94 -1.97 1.58 0.10 5.95 0.50 0.48 -3.74 6.14 10.28 3.30 -1.10 -4.10
Golgi 4.05 -1.74 2.43 0.27 3.14 -9.09 3.59 -1.57 3.68 -2.91 -2.70 9.21 0.75 2.17 -2.80
Lipid Particles 6.19 0.18 5.57 -1.25 4.23 -3.28 1.14 3.69 7.57 9.02 3.11 5.16 7.27 6.22 8.39
Mitochondria 1.15 13.52 11.32 4.45 -1.29 8.19 9.99 8.16 0.72 -3.98 7.08 13.47 7.33 1.50 -3.96
Mitotic Spindle -1.40 -6.22 -2.02 -1.72 -1.97 -2.18 -12.80 -2.65 -2.60 -2.50 -1.50 -15.97 -3.30 -2.76 -3.16
None 3.44 3.52 3.37 -1.30 -2.92 0.51 0.40 1.07 4.87 6.40 3.29 2.93 3.53 3.77 6.38
Nuclear Periphery 1.55 -1.76 -0.79 -1.94 0.92 3.35 -0.02 2.08 -2.81 5.08 3.12 -2.23 0.82 -3.14 4.40
Nuclear Periphery Foci 2.39 -6.11 -4.58 -6.23 4.92 1.03 0.14 0.73 -3.16 5.75 1.41 -2.36 -0.20 -5.59 6.26
Nucleolus 4.61 4.82 2.37 -0.71 -0.76 1.40 1.67 1.76 7.96 6.93 3.40 3.86 3.88 2.10 0.48
Nucleus 8.16 -3.54 -7.50 -11.21 -0.24 -0.63 -14.61 -2.33 -4.56 19.75 0.41 -24.29 -8.27 -11.59 19.88
Peroxisomes 1.49 10.10 10.58 7.10 0.28 -5.39 5.60 5.18 10.35 -0.88 -3.63 10.99 11.13 12.11 -0.83
Vacuole 8.98 -5.14 -11.61 -13.01 -1.56 -11.71 -26.28 -15.67 -7.84 5.29 -1.08 -22.65 -16.53 -16.38 0.01
Vacuole Periphery 2.06 14.50 -0.97 -1.23 -1.66 9.21 10.90 3.06 -1.54 -2.39 8.74 16.82 0.07 -1.89 -2.95
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Protein of unknown function, predicted to be palmitoylated; SWAT-GFP, seamless-GFP and mCherry C-terminal fusion proteins localize to the cytosol, while N-terminal GFP fusion protein localizes to the cell periphery; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cell periphery (57%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-3

YGL108C

YGL108C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ygl108c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available