Standard name
Human Ortholog
Description Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER; FLC3 has a paralog, FLC1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.27 0.23 0.16 0.16 0.13 0.09 0.13 0.1 0.13 – 0.1 0.1 0.27 0.12 0.07 0.15 0.14 0.13 0.05 0.09 0 0.06 0.09 0.05
Bud 0 0.05 0 0.05 0 0 0.07 0 0.11 – 0.15 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.07 0.05 0 0.05 0.06
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.53 0.46 0.39 0.39 0.27 0.27 0.3 0.26 0.28 – 0.31 0.31 0.57 0.5 0.48 0.88 0.88 0.9 0.63 0.57 0.67 0.73 0.68 0.63
Cytoplasm 0.38 0.44 0.65 0.68 0.68 0.73 0.7 0.76 0.69 – 0.74 0.73 0.52 0.63 0.67 0.07 0.07 0.08 0.15 0.11 0.09 0.09 0.05 0.14
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.05 0 0.05 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0.08 0.07 0.06 0.08 0.11 0.15 0.12 0.16 – 0.15 0.14 0.08 0 0 0.09 0.12 0.1 0 0 0.08 0 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0.05 0 0.11 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 28 72 42 41 44 30 47 38 32 – 20 26 45 15 15 88 81 57 6 32 12 5 16 10
Bud 3 17 11 13 11 13 26 16 27 – 29 30 7 1 1 7 7 7 1 6 5 1 2 1
Bud Neck 0 4 3 4 3 6 2 4 0 – 0 0 0 0 0 0 0 0 5 25 12 2 9 12
Bud Site 2 1 0 1 1 2 0 0 1 – 1 1 1 0 0 0 0 0 – – – – – –
Cell Periphery 55 144 104 102 90 88 108 96 69 – 61 78 96 62 100 526 502 403 85 209 186 63 127 124
Cytoplasm 40 137 173 178 225 241 251 278 168 – 146 186 87 78 139 40 40 34 19 41 25 7 9 27
Endoplasmic Reticulum 2 11 2 0 0 0 1 1 2 – 0 1 0 1 0 25 35 23 4 17 6 0 2 4
Endosome 0 0 0 0 0 1 0 0 0 – 0 0 0 0 0 2 0 0 0 3 0 0 0 2
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 5 7 1 1 0 0 0 0 1
Mitochondria 8 25 19 15 27 36 54 44 40 – 29 36 13 3 6 52 70 45 3 13 21 3 10 4
Nucleus 1 0 1 1 3 4 5 0 2 – 5 1 1 0 0 15 13 8 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 1 0 2 1 2 0 1 0 – 0 1 8 4 23 2 0 2 0 0 0 0 0 0
SpindlePole 0 1 5 6 15 6 6 12 4 – 2 3 1 0 0 9 13 7 0 2 0 0 0 0
Vac/Vac Membrane 0 1 1 0 4 3 2 5 2 – 0 6 0 0 0 1 1 1 3 8 3 0 3 3
Unique Cell Count 104 311 266 262 329 330 357 366 245 196 254 167 123 207 596 573 449 135 366 278 87 188 198
Labelled Cell Count 139 414 361 363 424 432 502 495 347 293 369 259 164 284 772 769 588 135 366 278 87 188 198


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.0 6.4 6.1 5.6 6.5 5.4 5.7 6.1 5.3 – 5.0 5.6 6.2 6.0 6.4 11.6 11.6 11.2 6.1 6.1 6.3
Std Deviation (1e-4) 1.7 1.8 1.2 1.3 1.4 1.3 1.4 1.2 1.3 – 1.0 1.1 2.0 1.9 2.6 1.7 1.5 1.5 1.9 2.0 2.0
Intensity Change (Log2) – – – -0.12 0.09 -0.19 -0.09 -0.0 -0.21 – -0.29 -0.14 0.03 -0.02 0.06 0.92 0.92 0.87 -0.01 -0.0 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 -0.8 -2.5 -0.9 -2.0 -0.9 – -1.7 -1.9 2.8 -0.9 -2.8 -0.4 -0.6 -1.2
Bud 0.5 -0.5 -0.1 1.6 0.1 3.0 – 4.0 3.2 0 0 -2.5 -2.8 -2.7 -2.1
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 -3.0 -3.2 -2.3 -3.4 -2.6 – -1.8 -2.0 3.7 2.1 2.0 15.0 14.6 14.4
Cytoplasm 0.7 0.9 2.1 1.4 3.0 0.8 – 2.2 2.0 -2.7 -0.3 0.5 -18.3 -18.0 -16.4
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 2.7 3.5 3.1
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria -0.7 0.5 1.6 3.1 2.0 3.2 – 2.7 2.6 0.2 -1.9 -2.0 0.8 2.2 1.3
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 5.6 0 0 0
SpindlePole 0.3 1.8 0 0 1.1 0 – 0 0 0 0 0 0 0.4 0
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8246 3.0851 2.2704 1.9372 2.1024 2.7301 0.7739 1.1827 0.879 0.4952 1.2535 1.0983 0.1502 0.6608 0.2474 0.4914 0.7418 0.6782
Actin 0.0223 0.0029 0.0166 0.0012 0.0096 0.0056 0.0535 0.0092 0.0239 0.0127 0.0582 0.0239 0.0393 0.0042 0.0314 0.0074 0.001 0.0114
Bud 0.0008 0.0006 0.0011 0.0009 0.0033 0.0013 0.003 0.0071 0.0051 0.0128 0.0052 0.0032 0.0013 0.0007 0.0018 0.0008 0.0002 0.0031
Bud Neck 0.0098 0.0037 0.007 0.0079 0.0177 0.0163 0.0078 0.0049 0.0139 0.0022 0.0201 0.0269 0.0098 0.0061 0.0068 0.0276 0.0063 0.0239
Bud Periphery 0.0055 0.0042 0.0121 0.0125 0.0455 0.0248 0.0251 0.0331 0.0516 0.1795 0.0738 0.0546 0.0096 0.0043 0.0198 0.0116 0.0026 0.0209
Bud Site 0.0252 0.1248 0.0315 0.0219 0.0064 0.0032 0.0331 0.183 0.0694 0.0064 0.0296 0.0059 0.0176 0.1615 0.0481 0.0132 0.0015 0.0045
Cell Periphery 0.3486 0.3813 0.3378 0.4871 0.3211 0.5263 0.4199 0.3901 0.3595 0.3229 0.4304 0.4959 0.367 0.3192 0.3939 0.3605 0.3522 0.4795
Cytoplasm 0.2288 0.2073 0.2735 0.2304 0.2678 0.2495 0.205 0.2772 0.2701 0.1385 0.2289 0.2276 0.2309 0.323 0.2854 0.247 0.3165 0.2604
Cytoplasmic Foci 0.0046 0.0022 0.0078 0.0034 0.0182 0.0034 0.0108 0.0009 0.0048 0.0036 0.0087 0.0071 0.0101 0.0038 0.0032 0.0034 0.0021 0.0094
Eisosomes 0.0105 0.0015 0.0066 0.0024 0.0053 0.0025 0.0139 0.0046 0.0109 0.0063 0.005 0.0038 0.0161 0.0041 0.0053 0.0016 0.0023 0.0028
Endoplasmic Reticulum 0.0025 0.0024 0.0036 0.0191 0.0082 0.0024 0.0071 0.0022 0.0038 0.0043 0.0048 0.0034 0.0051 0.0052 0.0061 0.0058 0.0022 0.0036
Endosome 0.0058 0.0005 0.0034 0.0013 0.0067 0.0014 0.0163 0.0001 0.0024 0.0083 0.0107 0.0079 0.0085 0.0003 0.002 0.0005 0.0001 0.0047
Golgi 0.0021 0.0006 0.0029 0.0006 0.0026 0.0009 0.0074 0.0003 0.0022 0.004 0.0128 0.0091 0.0046 0.0006 0.0038 0.0007 0.0001 0.0015
Lipid Particles 0.0024 0.0007 0.0098 0.0093 0.0112 0.003 0.0085 0.0002 0.0016 0.0227 0.0148 0.0051 0.0082 0.0013 0.0033 0.0023 0.0003 0.0015
Mitochondria 0.0049 0.0002 0.0057 0.0011 0.0006 0.0007 0.0149 0.001 0.0104 0.0089 0.0344 0.0084 0.0108 0.0002 0.0094 0.0001 0.0002 0.0011
None 0.3145 0.2653 0.265 0.1865 0.2626 0.1534 0.1469 0.0838 0.16 0.2312 0.0478 0.1067 0.2413 0.1625 0.1746 0.3141 0.3106 0.1545
Nuclear Periphery 0.0007 0.0001 0.0004 0.0008 0.0004 0.0003 0.0027 0.0002 0.0006 0.0014 0.0037 0.0006 0.0036 0.0003 0.0004 0.0003 0.0001 0.0109
Nucleolus 0.0008 0.0002 0.0005 0.0008 0.0008 0.0002 0.0009 0.0002 0.0005 0.002 0.0013 0.0003 0.0008 0.0003 0.0003 0.0002 0.0002 0.0004
Nucleus 0.0006 0.0003 0.0006 0.0012 0.0007 0.0004 0.0015 0.0005 0.0011 0.0092 0.002 0.0007 0.0021 0.0004 0.0004 0.0003 0.0003 0.0012
Peroxisomes 0.0032 0.0001 0.011 0.0003 0.0065 0.0008 0.0136 0.0001 0.0041 0.0031 0.0026 0.0046 0.0073 0.0002 0.0009 0.0001 0.0001 0.0007
Punctate Nuclear 0.0002 0.0001 0.0004 0.0003 0.0021 0.0002 0.0016 0.0001 0.0005 0.0004 0.0021 0.0008 0.002 0.0003 0.0003 0.0003 0.0002 0.001
Vacuole 0.0052 0.0012 0.0026 0.0108 0.0028 0.0033 0.0056 0.0013 0.0033 0.0171 0.0024 0.0033 0.0033 0.0015 0.0023 0.0022 0.0009 0.0025
Vacuole Periphery 0.001 0 0.0002 0.0002 0.0001 0.0001 0.0009 0 0.0004 0.0024 0.0006 0.0003 0.0007 0 0.0002 0.0001 0 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.0012 40.536 25.522 28.5583 26.4268 31.5869 44.5049 38.0013 28.4419 32.7526
Translational Efficiency 0.7901 0.7003 0.853 0.5073 0.5454 0.5858 0.66 0.594 0.6621 0.6202

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1404 770 387 552 181 1598 153 238 1585 2368 540 790

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 692.49 826.39 1180.33 1163.16 754.72 840.67 1158.82 1209.61 699.60 836.03 1174.24 1177.15
Standard Deviation 101.79 147.27 156.89 164.19 119.74 142.14 151.36 165.21 105.86 143.98 155.64 165.87
Intensity Change Log 2 — 0.255030 0.769325 0.748184 — 0.155598 0.618643 0.680529 — 0.204032 0.692710 0.713298

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.006083 0.015183 0.042541 0.024441 0.006193 0.010029 0.024483 0.018768 0.006096 0.011705 0.037425 0.022732
Bud Neck 0.054922 0.044098 0.038353 0.014811 0.039411 0.059208 0.017039 0.011897 0.053150 0.054295 0.032314 0.013933
Bud Site 0.068565 0.105915* 0.163735* 0.129107* 0.045575 0.097985 0.082745 0.084288 0.065940 0.100564* 0.140788* 0.115605*
Cell Periphery 0.259782* 0.240265* 0.289857* 0.684308* 0.216946* 0.285680* 0.551337* 0.693012* 0.254890* 0.270912* 0.363943* 0.686930*
Cytoplasm 0.433788* 0.329075* 0.073596 0.103056* 0.445278* 0.367088* 0.129531* 0.137631* 0.435100* 0.354727* 0.089444 0.113473*
Cytoplasmic Foci 0.056799 0.102737 0.009166 0.001387 0.103361 0.055757 0.020306 0.002547 0.062116 0.071034 0.012322 0.001736
Eisosomes 0.024303 0.013881 0.021880 0.007948 0.018329 0.019306 0.030319 0.009642 0.023621 0.017542 0.024271 0.008459
Endoplasmic Reticulum 0.003508 0.008593 0.193339* 0.006612 0.003196 0.004165 0.032667 0.005836 0.003472 0.005605 0.147815* 0.006378
Endosome 0.004719 0.010403 0.003683 0.000544 0.007655 0.009217 0.003318 0.001953 0.005054 0.009602 0.003580 0.000968
Golgi 0.003993 0.008014 0.002423 0.001371 0.004931 0.008735 0.004069 0.002138 0.004100 0.008501 0.002889 0.001602
Lipid Particles 0.007311 0.007358 0.008250 0.001450 0.010432 0.007154 0.004446 0.002158 0.007668 0.007220 0.007172 0.001664
Mitochondria 0.006367 0.006795 0.000493 0.000486 0.001497 0.010653 0.000178 0.000558 0.005811 0.009399 0.000404 0.000508
Mitotic Spindle 0.000260 0.000906 0.000358 0.000311 0.000076 0.002241 0.000370 0.000379 0.000239 0.001807 0.000362 0.000331
None 0.001399 0.001491 0.000162 0.000105 0.000508 0.000483 0.000062 0.000036 0.001297 0.000810 0.000134 0.000084
Nuclear Periphery 0.000119 0.000145 0.000617 0.000142 0.000196 0.000117 0.000268 0.000196 0.000128 0.000126 0.000518 0.000158
Nuclear Periphery Foci 0.000196 0.000590 0.004092 0.000419 0.000590 0.000368 0.002438 0.000494 0.000241 0.000441 0.003623 0.000442
Nucleolus 0.000385 0.000308 0.000064 0.000018 0.000256 0.000217 0.000032 0.000039 0.000370 0.000246 0.000055 0.000024
Nucleus 0.038787 0.056784 0.055114 0.006390 0.054006 0.025787 0.033579 0.002187 0.040525 0.035866 0.049012 0.005124
Peroxisomes 0.006109 0.012025 0.000653 0.000680 0.004588 0.008312 0.000791 0.000793 0.005936 0.009519 0.000692 0.000714
Vacuole 0.022017 0.034323 0.091444 0.016182 0.036562 0.025898 0.061865 0.022829 0.023678 0.028637 0.083063 0.018185
Vacuole Periphery 0.000589 0.001110 0.000180 0.000231 0.000415 0.001599 0.000156 0.002618 0.000569 0.001440 0.000173 0.000950

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.94 -9.13 -6.67 -2.93 3.60 -2.62 -4.66 -3.64 -2.62 1.15 -5.98 -10.17 -7.62 -4.90 3.79
Bud Neck 2.65 4.35 12.47 8.44 6.80 -2.95 3.37 4.29 14.83 1.88 -0.34 6.33 13.78 16.27 7.01
Bud Site -4.61 -9.10 -6.04 -2.06 2.29 -6.19 -3.40 -3.08 1.21 -0.15 -6.62 -8.98 -6.18 -1.87 2.14
Cell Periphery 1.33 -0.70 -23.50 -22.25 -19.93 -2.68 -8.67 -13.87 -16.02 -3.94 -1.37 -5.71 -27.57 -28.07 -17.79
Cytoplasm 8.68 37.92 31.08 18.86 -3.04 3.80 13.44 12.81 14.69 -0.40 8.97 38.22 32.93 27.70 -2.65
Cytoplasmic Foci -6.73 13.89 17.62 16.48 5.68 4.05 6.50 8.72 16.59 3.63 -2.08 13.85 19.43 23.59 6.13
Eisosomes 5.03 1.52 9.06 3.89 6.65 -0.36 -2.39 2.50 4.58 4.70 3.50 0.13 9.09 7.75 8.02
Endoplasmic Reticulum -3.53 -19.03 -2.75 1.13 18.63 -0.97 -6.38 -1.38 -0.93 5.48 -2.92 -18.28 -2.95 -0.77 17.81
Endosome -3.36 1.24 8.40 6.02 8.23 -0.94 2.63 3.48 5.49 1.13 -4.88 2.16 7.59 9.84 5.87
Golgi -3.38 4.72 2.86 4.60 1.03 -3.27 0.82 1.69 4.04 1.21 -6.04 3.60 3.16 6.88 1.52
Lipid Particles 0.04 -0.90 6.46 6.30 8.77 0.88 1.59 2.27 5.11 2.34 0.52 0.44 6.71 8.30 8.81
Mitochondria -0.25 6.91 6.89 4.95 0.19 -7.88 3.81 2.02 8.75 -1.20 -3.13 7.16 6.96 10.27 -0.76
Mitotic Spindle -1.46 -0.45 -0.13 1.56 1.44 -2.72 -6.14 -3.15 2.33 -0.08 -2.69 -0.64 -0.40 2.68 0.93
None -0.06 3.81 3.99 2.37 1.03 0.35 3.00 3.19 6.76 1.78 1.51 4.06 4.24 3.69 1.25
Nuclear Periphery -1.44 -10.51 -1.47 -0.17 9.43 1.16 -0.99 -0.03 -2.73 1.37 0.12 -10.21 -1.90 -2.08 9.03
Nuclear Periphery Foci -2.80 -10.92 -4.33 1.09 10.25 1.34 -4.93 0.55 -1.17 5.37 -2.32 -12.17 -4.53 -0.16 11.41
Nucleolus 0.92 3.20 3.73 5.23 3.92 0.48 2.70 2.54 3.97 -0.17 1.57 3.53 3.92 6.97 2.98
Nucleus -3.85 -4.10 10.49 10.56 8.61 4.12 1.42 7.45 10.87 3.58 1.67 -3.13 13.49 12.74 9.25
Peroxisomes -4.17 11.29 10.94 8.38 -0.20 -2.71 3.52 3.52 9.08 0.06 -4.34 11.76 11.53 12.39 -0.16
Vacuole -4.42 -11.18 0.59 3.43 10.54 2.15 -2.63 1.44 -0.09 3.50 -2.85 -11.54 0.59 2.17 10.88
Vacuole Periphery -2.32 6.95 4.32 3.92 -0.85 -2.79 3.92 -1.10 -0.49 -1.23 -2.93 7.52 -0.63 0.74 -1.29
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER; FLC3 has a paralog, FLC1, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (44%), cytoplasm (8%), mixed (20%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Flc3

Flc3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Flc3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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