ORF
Human Ortholog
Description Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0.06 0.08 0.06 0 0 0 0 0 0.05 0 0 0.05 0.07 0 0 0.05 0 0 0 0
Bud 0 0 0.07 0.08 0.08 0.1 0.11 0.11 0.09 0.07 0.08 0.08 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.07 0 0.11 0.13 0.15 0.13 0.13 0.07 0.11 0.17 0.14 0.15 0.29 0.25 0.26 0.06 0.05 0.08 0 0 0.05 0 0 0
Cytoplasm 0.46 0.74 0.74 0.79 0.65 0.87 0.85 0.91 0.89 0.87 0.9 0.9 0.79 0.81 0.88 0.81 0.72 0.82 0.07 0.24 0.14 0.12 0.17 0.12
Endoplasmic Reticulum 0.53 0.28 0.15 0.1 0.22 0.05 0.07 0 0 0 0 0 0.14 0.11 0.06 0.05 0.06 0.05 0.82 0.47 0.63 0.67 0.59 0.67
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.11 0.05 0.05 0.15 0.07 0.1 0.12 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 0 2 6 13 23 27 17 12 13 9 6 7 5 6 16 9 8 3 4 3 3 9 6
Bud 1 0 9 16 16 31 48 63 28 24 20 26 5 6 13 6 4 10 0 0 0 0 1 0
Bud Neck 0 0 0 0 0 0 1 1 0 1 0 0 0 0 0 0 1 0 3 3 2 3 5 8
Bud Site 0 0 0 0 0 0 0 2 0 1 0 0 0 0 1 1 2 1 – – – – – –
Cell Periphery 20 1 15 24 30 38 57 44 33 54 35 49 44 68 76 18 6 18 2 0 8 1 6 7
Cytoplasm 122 34 98 151 131 262 362 543 262 286 220 298 121 222 255 263 94 183 20 19 23 16 38 36
Endoplasmic Reticulum 141 13 20 19 45 15 28 15 5 12 2 7 22 30 16 15 8 12 247 38 103 97 136 212
Endosome 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 7 1 3 2 0 1 1 0 3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 4 3 0 0 0 1 0
Mitochondria 0 1 1 7 1 4 9 5 12 12 8 19 0 1 3 3 4 4 2 0 7 1 3 2
Nucleus 1 0 0 0 0 2 5 1 0 2 0 1 2 0 0 5 4 2 0 0 0 0 0 0
Nuclear Periphery 0 2 0 0 0 0 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 1 0 0 0 0 2 8 2 7 0 0 0 0 0 0
Vac/Vac Membrane 6 0 1 0 1 0 2 1 2 0 1 2 0 1 0 23 14 11 13 11 11 15 26 34
Unique Cell Count 267 46 133 190 203 300 426 598 296 327 244 330 153 275 289 325 131 222 301 82 164 146 231 315
Labelled Cell Count 299 51 146 223 237 376 541 695 354 406 296 408 201 333 372 367 151 266 301 82 164 146 231 315


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.6 6.7 5.8 5.8 6.4 6.1 5.6 5.4 5.3 5.1 5.1 4.9 7.5 6.9 5.8 24.5 20.3 22.9 7.8 7.7 8.1
Std Deviation (1e-4) 1.0 1.0 0.7 0.8 0.8 1.0 1.0 1.0 1.1 1.0 1.0 1.1 1.3 1.0 1.0 33.9 30.2 33.8 1.7 1.4 1.3
Intensity Change (Log2) – – – 0.02 0.14 0.09 -0.05 -0.09 -0.13 -0.18 -0.18 -0.23 0.37 0.25 0.01 2.08 1.82 1.99 0.43 0.42 0.49


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 2.1 2.5 2.2 0 0 0 0 0 0 0 0 1.7 2.2 0
Bud 0.5 0.4 1.2 1.5 1.3 0.9 0.2 0.5 0.4 -1.4 0 -1.0 0 -1.4 -0.9
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.4 0.9 0.4 0.6 -1.5 0 1.4 0.8 1.0 3.6 3.2 3.5 -2.2 -2.0 -1.0
Cytoplasm 1.2 -1.8 3.5 3.0 5.4 3.9 3.6 4.2 4.6 1.1 1.6 3.8 1.7 -0.4 2.0
Endoplasmic Reticulum -1.4 1.6 -3.5 -3.0 -6.1 -5.5 -4.3 -5.6 -5.4 -0.2 -1.2 -3.2 -3.8 -2.4 -3.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 2.4 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 2.8 3.5 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0789 3.6773 3.5974 3.4402 3.2945 3.9342 2.9049 3.6387 3.4222 3.2342 4.0449 3.7013 2.7022 4.9026 3.2932 3.2325 3.6747 3.5968
Actin 0.0006 0.001 0.0014 0.0026 0.0004 0.0006 0.0339 0.0037 0.0121 0.0079 0.0476 0.0027 0.0006 0.0016 0.0019 0.001 0.0003 0.0008
Bud 0 0.0001 0.0001 0.0001 0.0002 0 0.0004 0.0003 0.0005 0.0003 0.0006 0.0001 0 0.0002 0.0001 0.0001 0.0001 0.0001
Bud Neck 0.0005 0.0005 0.0013 0.0026 0.0018 0.0034 0.0022 0.0049 0.0017 0.0028 0.0087 0.0052 0.0001 0.0004 0.0023 0.0006 0.0018 0.0025
Bud Periphery 0.0001 0.0001 0.0002 0.0003 0.0002 0.0001 0.0006 0.0006 0.0006 0.0006 0.0011 0.0003 0.0001 0.0002 0.0002 0.0005 0.0008 0.0003
Bud Site 0.0006 0.0023 0.0018 0.0005 0.0004 0.0001 0.0031 0.0094 0.0076 0.001 0.0009 0.0003 0.0003 0.0048 0.009 0.0004 0.0007 0.0002
Cell Periphery 0.0085 0.0136 0.0048 0.0055 0.0026 0.0033 0.0073 0.0176 0.0048 0.0061 0.0035 0.0051 0.0055 0.0117 0.0085 0.0053 0.0236 0.0046
Cytoplasm 0.6783 0.6831 0.7387 0.6745 0.8123 0.709 0.3602 0.571 0.5936 0.568 0.4391 0.5624 0.4742 0.6044 0.5016 0.5884 0.7639 0.6373
Cytoplasmic Foci 0.0059 0.0115 0.012 0.008 0.006 0.005 0.0339 0.0163 0.0176 0.044 0.028 0.0122 0.0114 0.014 0.0145 0.0045 0.008 0.0184
Eisosomes 0.0001 0.0001 0.0001 0 0 0 0.0006 0.0003 0.0002 0.0003 0.0004 0 0.0001 0.0002 0.0001 0.0006 0.0001 0
Endoplasmic Reticulum 0.1824 0.1857 0.1275 0.1983 0.0692 0.1796 0.271 0.1721 0.2092 0.1145 0.1697 0.2104 0.3241 0.118 0.2405 0.0743 0.1348 0.1789
Endosome 0.0039 0.0073 0.014 0.011 0.0187 0.0082 0.0717 0.0251 0.0363 0.0581 0.14 0.0291 0.0085 0.0175 0.0329 0.0048 0.0105 0.0119
Golgi 0.0007 0.001 0.0008 0.0025 0.0004 0.0006 0.0126 0.0025 0.007 0.0164 0.048 0.0083 0.002 0.0018 0.0054 0.0009 0.0006 0.0008
Lipid Particles 0.0152 0.0368 0.0169 0.0108 0.0042 0.0044 0.0554 0.053 0.0138 0.0253 0.0294 0.0153 0.0463 0.0275 0.0326 0.004 0.008 0.0165
Mitochondria 0 0 0.0001 0.0001 0.0002 0.0001 0.0066 0.0021 0.007 0.0077 0.015 0.005 0.0001 0.0001 0.0005 0.0006 0.0001 0.0002
None 0.0915 0.0396 0.0479 0.0061 0.0242 0.0439 0.0739 0.0529 0.0377 0.0468 0.0094 0.0375 0.1055 0.1333 0.0715 0.2818 0.0102 0.1024
Nuclear Periphery 0.0031 0.003 0.0035 0.0029 0.0045 0.0032 0.017 0.0046 0.0049 0.0056 0.0159 0.0147 0.0077 0.0027 0.0053 0.002 0.002 0.002
Nucleolus 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0006 0.0015 0.0002 0.0018 0.0008 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001
Nucleus 0.001 0.0011 0.0015 0.0016 0.0057 0.0019 0.003 0.0029 0.0018 0.0032 0.0058 0.0042 0.0024 0.0014 0.0014 0.0006 0.0008 0.001
Peroxisomes 0 0.0001 0.0001 0 0 0 0.008 0.0007 0.0021 0.0087 0.0015 0.0009 0.0001 0.0001 0.0141 0.0001 0 0.0001
Punctate Nuclear 0.0005 0.0007 0.0008 0.0004 0.0006 0.0004 0.0037 0.0019 0.0008 0.0094 0.0076 0.0013 0.0004 0.001 0.0006 0.0002 0.0002 0.0004
Vacuole 0.0068 0.0122 0.0259 0.0708 0.0472 0.0356 0.032 0.0561 0.0396 0.0694 0.0249 0.0835 0.0103 0.0585 0.0557 0.0287 0.0329 0.021
Vacuole Periphery 0.0001 0.0001 0.0005 0.0012 0.0012 0.0004 0.0023 0.0006 0.0009 0.0021 0.0023 0.0015 0.0002 0.0006 0.001 0.0005 0.0004 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.2984 21.8296 33.597 33.8292 25.6025 21.9956 34.1979 35.5874 34.9926 36.2714
Translational Efficiency 0.4024 0.4522 0.3802 0.3696 0.3993 0.5183 0.3305 0.3437 0.3628 0.3356

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1165 41 750 1390 1749 1194 239 216 2914 1235 989 1606

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 763.91 312.80 1215.26 967.86 848.39 860.88 1144.30 1051.27 814.62 842.68 1198.11 979.08
Standard Deviation 119.75 13.02 137.95 138.92 112.86 119.30 116.69 137.74 122.85 152.99 136.55 141.65
Intensity Change Log 2 — -1.288162 0.669790 0.341396 — 0.021085 0.431666 0.309334 — -0.458081 0.549398 0.324614

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001130 0.000039 0.000553 0.017893 0.001230 0.001763 0.010309 0.029221 0.001190 0.001706 0.002910 0.019417
Bud Neck 0.014172 0.000006 0.006472 0.021983 0.011641 0.017013 0.008359 0.025622 0.012653 0.016448 0.006928 0.022472
Bud Site 0.006617 0.000013 0.020637 0.059233 0.007491 0.011463 0.020724 0.069701 0.007142 0.011083 0.020658 0.060641
Cell Periphery 0.010375 0.000049 0.001042 0.007970 0.007054 0.008242 0.020918 0.024455 0.008382 0.007970 0.005845 0.010187
Cytoplasm 0.526089* 0.000029 0.608416* 0.333322* 0.392300* 0.396488* 0.201442* 0.276716* 0.445788* 0.383326* 0.510068* 0.325708*
Cytoplasmic Foci 0.086802 0.000017 0.029125 0.073535 0.056395 0.062249 0.059313 0.072900 0.068551 0.060183 0.036420 0.073450
Eisosomes 0.012567 0.000053 0.000181 0.007137 0.005187 0.006472 0.006710 0.015980 0.008138 0.006259 0.001759 0.008327
Endoplasmic Reticulum 0.132922* 0.000001 0.019111 0.040578 0.352860* 0.281349* 0.263831* 0.079456 0.264930* 0.272008* 0.078250 0.045807
Endosome 0.011418 0.000001 0.003502 0.017584 0.011023 0.018894 0.012040 0.010029 0.011181 0.018267 0.005565 0.016568
Golgi 0.022905 0.000005 0.000361 0.004641 0.027083 0.032426 0.002173 0.001879 0.025413 0.031349 0.000799 0.004269
Lipid Particles 0.052887 0.000021 0.007742 0.022627 0.040450 0.049576 0.031212 0.029749 0.045422 0.047931 0.013414 0.023585
Mitochondria 0.003018 0.000010 0.000292 0.003947 0.004736 0.006593 0.000088 0.000524 0.004049 0.006374 0.000243 0.003487
Mitotic Spindle 0.000062 0.000338 0.000105 0.010391 0.000247 0.000401 0.004082 0.000210 0.000173 0.000399 0.001066 0.009022
None 0.009832 0.999270* 0.001204 0.001839 0.004529 0.002601 0.000106 0.001519 0.006649 0.035688 0.000939 0.001796
Nuclear Periphery 0.000938 0.000000 0.000572 0.000769 0.000408 0.000491 0.002388 0.000357 0.000620 0.000475 0.001011 0.000713
Nuclear Periphery Foci 0.004463 0.000026 0.012117 0.008502 0.002761 0.003176 0.039564 0.017011 0.003442 0.003071 0.018750 0.009646
Nucleolus 0.001101 0.000024 0.000415 0.000430 0.000383 0.000935 0.000108 0.000121 0.000670 0.000905 0.000341 0.000388
Nucleus 0.052449 0.000009 0.091543 0.054291 0.021734 0.021598 0.060218 0.034256 0.034013 0.020882 0.083973 0.051596
Peroxisomes 0.005805 0.000089 0.000344 0.004339 0.005089 0.006526 0.000835 0.003040 0.005375 0.006312 0.000463 0.004165
Vacuole 0.043731 0.000001 0.196083 0.306711* 0.045684 0.069245 0.255414* 0.307096* 0.044903 0.066946 0.210421* 0.306763*
Vacuole Periphery 0.000715 0.000000 0.000182 0.002278 0.001715 0.002500 0.000166 0.000160 0.001315 0.002417 0.000178 0.001993

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 7.42 3.59 -9.78 -10.51 -10.17 -2.29 -4.04 -5.38 -5.26 -3.24 -2.36 -3.03 -11.11 -10.68 -9.43
Bud Neck 12.75 6.40 -3.32 -14.36 -9.20 -2.82 2.30 -3.27 -1.77 -4.25 -2.25 6.26 -5.17 -2.12 -10.01
Bud Site 9.12 -4.51 -13.68 -15.87 -8.28 -2.77 -4.96 -7.54 -6.96 -5.57 -2.96 -5.69 -15.38 -13.33 -9.76
Cell Periphery 13.43 12.05 3.35 -11.65 -9.90 -1.42 -3.26 -3.70 -3.39 -0.36 0.53 2.64 -0.80 -1.13 -2.87
Cytoplasm 80.88* -7.04 21.55 -47.96* 26.99 -0.44 13.79 7.62 7.68 -3.44 7.48 -5.67 16.82 7.17 17.59
Cytoplasmic Foci 24.90 14.04 3.75 -26.09 -11.89 -1.67 -0.57 -2.45 -1.58 -1.63 2.60 10.98 -0.72 -2.98 -10.29
Eisosomes 11.37 11.27 4.81 -8.84 -8.68 -2.32 -0.80 -3.02 -2.59 -2.37 2.93 10.51 0.88 -1.31 -6.94
Endoplasmic Reticulum 21.34* 17.55 13.98 -12.34 -5.26 6.15 4.96 21.11 15.19 8.26 -0.70 23.54 34.91 25.80 5.01
Endosome 14.66 9.76 -3.21 -13.20 -10.15 -6.16 -1.17 0.96 4.70 1.49 -5.75 11.09 -3.46 1.93 -8.61
Golgi 18.74* 18.45 13.42 -5.62 -5.14 -3.10 23.48 23.94 21.97 1.06 -3.82 31.06 21.79 18.77 -4.72
Lipid Particles 20.38* 16.72 11.02 -18.05 -9.79 -3.70 3.30 3.73 6.16 0.66 -1.06 19.50 12.97 11.72 -6.35
Mitochondria 5.68 5.20 -0.39 -4.66 -4.31 -1.76 9.67 7.23 6.07 -1.10 -2.37 10.69 1.49 3.07 -4.41
Mitotic Spindle -5.08 -2.22 -5.06 -4.91 -5.00 -0.52 -0.97 -0.93 -0.74 0.74 -0.90 -0.98 -5.04 -4.87 -3.92
None -616.11* 5.46 4.74 1443.81* -0.77 2.11 6.55 2.73 1.10 -1.36 -5.61 7.57 5.24 6.62 -1.21
Nuclear Periphery 6.75 2.40 0.87 -6.38 -1.47 -1.02 -3.90 1.04 1.59 4.00 1.55 -2.81 -0.83 -1.91 1.81
Nuclear Periphery Foci 8.68 -7.17 -4.41 -11.45 3.62 -1.09 -10.66 -8.55 -8.20 6.03 0.87 -12.81 -8.42 -8.63 7.13
Nucleolus 3.83 2.56 2.50 -5.92 -0.06 -1.91 9.60 9.60 2.80 -0.44 -0.75 3.04 2.52 1.92 -0.62
Nucleus 27.25 -10.79 -0.82 -25.52 9.78 0.06 -6.71 -3.50 -3.41 4.12 8.24 -17.31 -8.34 -13.57 9.58
Peroxisomes 15.93 15.17 3.14 -7.81 -7.30 -3.13 14.88 3.94 5.92 -3.95 -2.24 22.14 3.36 4.56 -7.71
Vacuole 22.55 -25.25 -38.97 -46.35 -13.21 -6.17 -14.90 -16.55 -15.05 -2.88 -6.36 -28.97 -42.53 -36.40 -12.46
Vacuole Periphery 15.09 11.02 -3.23 -5.13 -4.69 -1.76 4.55 4.56 8.05 0.27 -3.19 5.58 -1.02 1.64 -4.68
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains
Localization
Cell Percentages ER (83%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

YGL140C

YGL140C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ygl140c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available