Standard name
Human Ortholog
Description DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family of DNA translocases; forms nuclear foci upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0.05 0 0.05 0.05 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.78 0.74 0.92 0.86 0.74 0.77 0.79 0.86 0.75 – 0.64 0.75 0.66 0.71 0.71 0.39 0.34 0.34 0.56 0.48 0.53 0.7 0.75 0.67
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.08 0.07 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0.08 0.08 0.06 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0.13 0 0 0 0.21 0.15 0.13 0.29 – 0.56 0.27 0.05 0 0 0.06 0 0.09 0 0.08 0.1 0.12 0.09 0.09
Nucleus 0.09 0.11 0 0.06 0.13 0.08 0.07 0 0.05 – 0.05 0.06 0.25 0.19 0.16 0.26 0.29 0.28 0.14 0.16 0.05 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0.07 0.08 0 0 0
Vac/Vac Membrane 0.09 0.11 0 0 0.07 0 0 0 0 – 0 0 0.06 0.07 0.09 0.3 0.27 0.31 0.1 0.12 0.11 0.05 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 2 4 5 8
Bud 0 3 0 0 1 0 1 0 2 – 5 4 0 0 0 0 1 1 2 3 1 6 5 12
Bud Neck 0 1 8 9 11 5 14 13 2 – 6 4 1 0 0 0 1 1 1 1 0 1 2 4
Bud Site 0 0 0 0 0 0 2 0 3 – 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 1 1 1 1 2 1 – 0 1 0 0 0 1 0 1 0 0 2 2 5 2
Cytoplasm 73 104 166 181 163 142 238 209 159 – 109 121 150 179 212 111 62 55 64 77 107 140 261 202
Endoplasmic Reticulum 0 0 1 1 0 0 0 0 0 – 0 0 0 0 1 22 12 12 1 0 2 1 2 5
Endosome 1 0 0 0 1 0 1 0 1 – 0 0 1 13 8 22 14 9 1 2 2 0 2 3
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 3 0 1 0 1 0 0 1
Mitochondria 8 18 0 7 8 38 46 32 61 – 95 43 11 3 6 16 5 14 3 12 20 24 32 28
Nucleus 8 16 2 12 29 14 21 6 11 – 8 9 57 47 49 76 53 45 16 26 10 0 0 1
Nuclear Periphery 0 1 0 0 0 1 0 0 0 – 0 0 0 1 0 0 0 1 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 0 0 1 – 0 0 1 2 1 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 1 0 2 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 6 3 5 3 6 5 4 – 1 4 2 2 2 2 3 1 5 11 15 1 5 2
Vac/Vac Membrane 8 15 3 3 15 0 3 0 4 – 0 0 14 17 28 86 49 49 11 19 21 10 15 18
Unique Cell Count 93 140 181 211 220 184 300 244 212 171 161 226 253 298 287 180 160 115 163 203 202 349 302
Labelled Cell Count 98 158 187 217 235 204 333 267 249 224 187 238 264 309 337 203 189 115 163 203 202 349 302


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.0 3.8 5.3 3.9 5.3 3.9 3.8 4.0 4.2 – 2.8 3.3 4.1 4.4 4.3 6.3 6.6 6.4 4.0 3.9 4.5
Std Deviation (1e-4) 1.0 0.7 3.6 1.1 3.7 2.6 1.3 1.5 4.3 – 0.9 1.3 1.4 1.8 1.7 1.7 2.4 2.8 1.8 1.7 2.5
Intensity Change (Log2) – – – -0.43 0.01 -0.43 -0.49 -0.42 -0.32 – -0.91 -0.67 -0.36 -0.26 -0.3 0.25 0.33 0.27 -0.4 -0.43 -0.22


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 7.6 6.9 7.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9376 1.7016 1.4381 1.4548 0.5079 1.1765 -0.7885 -0.9048 -0.703 -1.0221 -1.3042 -1.1778 -1.3299 -0.6316 -0.4632 -0.8642 -0.5936 -0.6729
Actin 0.0277 0.0002 0.0169 0.0031 0.0009 0.0142 0.0309 0.0007 0.0084 0.0003 0.0002 0.0051 0.0089 0.0002 0.0051 0.0007 0.0007 0.0006
Bud 0.0009 0.0011 0.0001 0.0006 0.0002 0.001 0.002 0.0012 0.0058 0 0.0002 0.0005 0.0048 0.0042 0.0127 0.0139 0.0136 0.0103
Bud Neck 0.0028 0.0003 0.0004 0.0007 0.0027 0.007 0.0042 0.0008 0.0033 0.0008 0.004 0.0042 0.0009 0.0006 0.0007 0.0005 0.0014 0.0038
Bud Periphery 0.0032 0.0006 0.0002 0.0007 0.0004 0.0053 0.0054 0.0013 0.0041 0 0.0001 0.0014 0.0012 0.001 0.0041 0.0056 0.0056 0.0041
Bud Site 0.005 0.005 0.0005 0.0025 0.0005 0.0004 0.0057 0.0193 0.0151 0.0001 0.0001 0.0003 0.0066 0.0062 0.0052 0.0004 0.0013 0.0008
Cell Periphery 0.0011 0.0002 0.0001 0.0001 0.0002 0.0004 0.0006 0.0002 0.0007 0 0 0.0002 0.0003 0.0001 0.0002 0.0001 0.0002 0.0002
Cytoplasm 0.0689 0.0999 0.0849 0.0888 0.1146 0.1268 0.1051 0.1684 0.1017 0.0819 0.1889 0.2272 0.0769 0.0959 0.0697 0.0878 0.1219 0.1302
Cytoplasmic Foci 0.052 0.002 0.0155 0.0211 0.0455 0.0071 0.0363 0.01 0.0174 0.0025 0.0081 0.0137 0.0188 0.006 0.0106 0.0027 0.0273 0.0156
Eisosomes 0.0013 0.0002 0.0003 0.0001 0.0002 0.0004 0.0005 0.0001 0.0003 0 0 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0089 0.0015 0.0026 0.0019 0.0032 0.0024 0.0103 0.0031 0.0033 0.001 0.0036 0.0028 0.002 0.0011 0.001 0.0019 0.0018 0.0012
Endosome 0.0248 0.0011 0.0123 0.0196 0.011 0.0038 0.0267 0.0056 0.0098 0.0024 0.0046 0.0055 0.0024 0.0011 0.0026 0.0026 0.0035 0.0012
Golgi 0.0097 0 0.0044 0.0083 0.001 0.0039 0.0111 0.0003 0.004 0.0001 0.0001 0.0005 0.0004 0.0001 0.0003 0.0001 0.0002 0.0001
Lipid Particles 0.0448 0.0002 0.0153 0.0182 0.012 0.0079 0.0336 0.0017 0.0092 0.0006 0.0004 0.001 0.0011 0.0004 0.0016 0.0005 0.0008 0.0003
Mitochondria 0.0104 0.0003 0.0106 0.077 0.0037 0.0073 0.0238 0.0009 0.0126 0.0009 0.0006 0.0013 0.0015 0.0005 0.0025 0.0007 0.0023 0.001
None 0.6204 0.7204 0.4449 0.3574 0.6499 0.6664 0.548 0.459 0.2594 0.2023 0.2761 0.417 0.7301 0.5323 0.2594 0.3916 0.5064 0.5025
Nuclear Periphery 0.0061 0.0039 0.0084 0.0054 0.0145 0.0032 0.0164 0.0076 0.0203 0.0137 0.0069 0.0132 0.0047 0.0057 0.0124 0.0133 0.0133 0.0049
Nucleolus 0.0022 0.0025 0.0058 0.0037 0.0093 0.0017 0.0026 0.0033 0.0081 0.0091 0.0069 0.0034 0.0066 0.0081 0.0078 0.0025 0.0098 0.0101
Nucleus 0.0544 0.135 0.327 0.3214 0.0776 0.1136 0.0797 0.2678 0.4588 0.5907 0.4167 0.2541 0.1022 0.2694 0.5126 0.3546 0.201 0.2137
Peroxisomes 0.0353 0 0.006 0.0489 0.0157 0.0091 0.0264 0.0007 0.0055 0.0002 0.0001 0.0011 0.0008 0.0001 0.0034 0.0002 0.0005 0.0002
Punctate Nuclear 0.0144 0.0243 0.0424 0.0174 0.0316 0.0159 0.0228 0.0443 0.0475 0.0923 0.0802 0.0447 0.0263 0.0659 0.0865 0.1188 0.0854 0.0977
Vacuole 0.0047 0.001 0.0009 0.0023 0.0038 0.0019 0.006 0.0032 0.0035 0.0007 0.0017 0.0022 0.0029 0.0009 0.0014 0.0009 0.0023 0.0012
Vacuole Periphery 0.0011 0.0001 0.0004 0.0008 0.0014 0.0003 0.0021 0.0004 0.0014 0.0003 0.0003 0.0005 0.0005 0.0001 0.0003 0.0004 0.0007 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.0919 14.995 6.5133 8.7296 20.9526 19.2181 11.0013 10.3577 10.5527 16.2915
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2196 1637 1408 160 607 1802 290 78 2803 3439 1698 238

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 632.90 696.57 841.55 897.65 608.32 702.52 831.68 848.32 627.58 699.69 839.86 881.48
Standard Deviation 65.62 106.17 103.45 132.76 96.53 91.63 100.50 125.00 74.12 98.86 103.02 132.31
Intensity Change Log 2 — 0.138291 0.411071 0.504175 — 0.207709 0.451198 0.479778 — 0.172730 0.430877 0.492270

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000051 0.000343 0.000411 0.001826 0.000076 0.000321 0.000258 0.000391 0.000057 0.000332 0.000385 0.001356
Bud Neck 0.010888 0.024542 0.006438 0.016972 0.014047 0.040793 0.002392 0.001925 0.011572 0.033058 0.005747 0.012041
Bud Site 0.002443 0.008677 0.004916 0.025943 0.002303 0.010508 0.001928 0.007616 0.002413 0.009636 0.004406 0.019937
Cell Periphery 0.000167 0.000170 0.000134 0.000543 0.000244 0.000230 0.000107 0.000075 0.000184 0.000201 0.000130 0.000390
Cytoplasm 0.410020* 0.360499* 0.047442 0.103118* 0.355748* 0.321364* 0.046631 0.092920 0.398267* 0.339992* 0.047303 0.099776
Cytoplasmic Foci 0.093006 0.159531 0.001814 0.008975 0.202814* 0.208656* 0.003567 0.004303 0.116785 0.185272* 0.002114 0.007444
Eisosomes 0.000084 0.000086 0.000030 0.000048 0.000330 0.000159 0.000050 0.000045 0.000137 0.000124 0.000033 0.000047
Endoplasmic Reticulum 0.000402 0.001230 0.004828 0.006480 0.000727 0.000932 0.003623 0.004280 0.000473 0.001074 0.004622 0.005759
Endosome 0.002843 0.011145 0.000733 0.028387 0.007590 0.021905 0.000772 0.000680 0.003871 0.016783 0.000739 0.019307
Golgi 0.000457 0.002677 0.000047 0.002200 0.001545 0.005322 0.000038 0.000041 0.000693 0.004063 0.000046 0.001492
Lipid Particles 0.006012 0.007853 0.000830 0.001060 0.011755 0.012253 0.001176 0.001097 0.007256 0.010158 0.000889 0.001072
Mitochondria 0.003923 0.014490 0.001615 0.003424 0.008554 0.020438 0.000434 0.000727 0.004926 0.017607 0.001414 0.002540
Mitotic Spindle 0.004251 0.007939 0.002102 0.099671 0.002448 0.012180 0.000286 0.002807 0.003861 0.010162 0.001792 0.067926
None 0.009909 0.008160 0.004066 0.029038 0.018407 0.006854 0.006153 0.003317 0.011749 0.007475 0.004422 0.020609
Nuclear Periphery 0.000768 0.000986 0.001834 0.002135 0.000838 0.001028 0.001049 0.001371 0.000783 0.001008 0.001700 0.001885
Nuclear Periphery Foci 0.000181 0.000836 0.000373 0.001159 0.000518 0.000666 0.000225 0.000330 0.000254 0.000747 0.000348 0.000888
Nucleolus 0.002836 0.005156 0.001339 0.003750 0.004515 0.004852 0.001943 0.000794 0.003200 0.004997 0.001442 0.002781
Nucleus 0.434903* 0.335160* 0.908322* 0.513913* 0.337504* 0.262017* 0.916933* 0.855830* 0.413811* 0.296834* 0.909793* 0.625970*
Peroxisomes 0.002300 0.016350 0.000343 0.001956 0.007930 0.020373 0.000193 0.000248 0.003519 0.018458 0.000317 0.001396
Vacuole 0.013959 0.032860 0.012221 0.127646 0.021383 0.046253 0.012114 0.021105 0.015567 0.039877 0.012203 0.092729
Vacuole Periphery 0.000597 0.001310 0.000161 0.021755 0.000722 0.002897 0.000129 0.000099 0.000624 0.002142 0.000156 0.014658

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.85 -10.00 -8.30 -6.82 -5.87 -5.48 -5.03 -3.96 -3.19 -2.54 -8.23 -11.08 -9.06 -7.46 -6.20
Bud Neck -7.01 1.84 -3.23 3.48 -4.86 -8.53 3.14 2.21 12.34 -1.17 -12.83 3.05 -1.48 10.67 -4.28
Bud Site -4.82 -2.73 -5.15 -2.30 -3.74 -7.21 -0.74 -2.16 -0.66 -1.90 -8.29 -2.86 -5.01 -1.94 -3.79
Cell Periphery -0.07 1.47 -1.82 -1.74 -2.29 0.52 4.58 3.65 4.02 -0.67 -1.02 2.84 -1.02 -0.60 -2.23
Cytoplasm 6.11 58.19 25.79 20.47 -3.01 2.38 24.91 11.91 11.46 -2.02 8.75 62.97 28.24 23.10 -3.69
Cytoplasmic Foci -11.54 29.27 28.36 31.92 -2.34 -0.33 23.45 23.08 39.34 -0.43 -14.26 36.16 35.07 51.03 -2.28
Eisosomes -0.93 11.57 -3.12 -2.72 -8.00 1.39 2.21 1.83 3.12 -2.61 0.39 3.65 0.87 1.46 -8.35
Endoplasmic Reticulum -6.38 -20.48 -8.40 -7.94 -4.95 -1.72 -8.69 -5.97 -5.83 -2.80 -7.39 -22.14 -9.99 -9.54 -5.47
Endosome -8.06 5.21 -2.09 1.69 -3.00 -8.21 6.51 4.06 12.24 -1.97 -13.85 8.10 -1.25 6.52 -3.31
Golgi -5.11 6.18 -0.69 4.40 -2.81 -5.46 4.21 3.78 8.71 -2.18 -8.83 6.90 1.42 9.16 -3.11
Lipid Particles -2.34 10.72 8.06 8.90 -4.69 0.10 8.51 7.77 12.14 -1.78 -4.04 13.66 10.97 15.38 -5.13
Mitochondria -6.47 3.12 2.64 8.16 -0.99 -4.10 3.15 2.74 11.51 -1.86 -9.63 4.33 3.88 14.05 -1.13
Mitotic Spindle -1.36 0.45 -3.55 -3.32 -3.62 -3.55 -0.80 -2.11 -1.17 -1.66 -3.41 0.00 -4.04 -3.40 -4.03
None 1.62 5.80 -0.29 -0.78 -2.07 3.23 3.34 4.24 3.53 2.23 3.78 6.59 1.28 -0.39 -1.81
Nuclear Periphery -2.64 -12.64 -9.88 -9.26 -4.28 -1.63 -4.39 -3.92 -3.63 -3.05 -2.94 -13.35 -9.52 -8.77 -4.62
Nuclear Periphery Foci -3.49 -4.13 -2.93 -2.03 -2.52 -0.58 1.76 -2.06 -1.45 -3.11 -3.31 -2.51 -3.45 -2.33 -3.10
Nucleolus -3.20 0.96 -0.18 1.85 -0.73 -0.01 1.21 1.30 1.51 0.24 -3.14 1.51 0.32 2.32 -0.67
Nucleus 10.26 -60.37 -6.70 -10.25 10.76 5.68 -34.56 -9.38 -11.62 4.68 15.73 -69.71 -10.34 -15.65 11.61
Peroxisomes -10.47 8.40 6.41 11.86 -1.88 -6.94 7.23 6.81 15.04 -1.27 -15.17 10.73 9.30 19.11 -2.09
Vacuole -10.74 -2.70 -8.23 -7.09 -7.98 -8.49 -1.56 -4.40 -3.43 -3.91 -15.92 -2.85 -9.36 -7.66 -8.99
Vacuole Periphery -2.91 2.03 -1.91 -1.54 -2.16 -4.22 4.93 3.87 5.24 -1.36 -4.74 2.72 -1.78 -0.55 -2.17
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family of DNA translocases; forms nuclear foci upon DNA replication stress
Localization
Cell Percentages nucleus (21%), cytoplasm (4%), mixed (45%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rad54

Rad54


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad54-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available