Standard name
Human Ortholog
Description Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0.09 0.07 0.07 0.05 0.08 0 0.07 0.05 0.05 0.1 0.14 0.27 0.24 0.1 – 0 0 0 0.05 0.11 0.12
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.15 – 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 0.08 0 0 0 0 0.19 0.32 0.17 0.19 0.39 0.39 0.36 0 0 0 0 0 – 0 0 0 0 0 0
Nucleus 0.94 0.74 0.86 0.83 0.76 0.68 0.7 0.68 0.74 0.63 0.61 0.62 0.85 0.8 0.58 0.42 0.5 – 0.89 0.96 0.84 0.77 0.59 0.46
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0.07 0.21 0 0 0 0.05 0 0.07 0.08 0.1 0.14 0.09 0 0 0 0 0 – 0 0 0.05 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.07
Vac/Vac Membrane 0 0.32 0.08 0.05 0.13 0.15 0.07 0.1 0.07 0.09 0.1 0.07 0 0.1 0.19 0.31 0.4 – 0 0 0 0.06 0.14 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1
Bud 0 0 0 0 0 1 6 7 0 4 5 4 0 0 0 0 0 – 1 0 3 2 12 21
Bud Neck 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 – 0 0 0 0 1 3
Bud Site 0 0 0 0 0 3 7 13 5 13 10 14 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 2 0 12 19 24 30 27 43 15 38 21 25 20 60 116 17 2 – 1 0 2 8 36 51
Endoplasmic Reticulum 0 0 0 0 0 1 2 0 0 0 0 1 0 1 0 2 0 – 0 0 1 0 1 2
Endosome 0 0 3 2 13 8 5 17 4 4 2 3 2 3 17 9 3 – 0 0 2 1 4 20
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 11 0 3 4 15 78 169 98 78 220 168 170 0 0 0 3 0 – 0 0 2 1 5 5
Nucleus 127 14 217 176 257 276 372 383 309 358 265 292 174 349 253 30 10 – 126 48 228 119 189 193
Nuclear Periphery 0 0 1 0 0 1 1 5 1 0 0 5 0 0 0 0 0 – 0 0 0 0 0 2
Nucleolus 9 4 6 6 8 19 23 41 35 57 59 42 1 0 0 1 0 – 5 1 12 2 9 15
Peroxisomes 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 1 1 0 2 0 0 1 0 1 2 1 0 – 1 0 2 3 8 27
Vac/Vac Membrane 3 6 19 11 45 63 37 56 28 51 42 35 9 44 81 22 8 – 4 0 11 9 46 64
Unique Cell Count 135 19 251 211 340 407 531 564 415 564 431 470 204 438 433 72 20 142 51 271 156 323 422
Labelled Cell Count 152 24 261 218 363 481 652 665 477 745 572 592 206 458 469 85 23 142 51 271 156 323 422


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.5 7.7 7.9 7.2 6.5 5.8 5.8 5.8 6.1 5.7 5.7 5.5 9.3 9.0 7.9 10.5 11.3 – 7.7 8.1 8.1
Std Deviation (1e-4) 0.9 1.4 1.2 1.5 1.4 1.2 1.3 1.4 1.2 1.3 1.3 1.2 1.5 1.7 1.4 2.3 2.5 – 1.4 1.4 1.5
Intensity Change (Log2) – – – -0.12 -0.28 -0.45 -0.45 -0.44 -0.38 -0.46 -0.46 -0.5 0.25 0.19 0.02 0.42 0.52 – -0.03 0.04 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cytoplasm 1.8 1.1 1.3 0.2 1.5 -0.7 1.1 0.1 0.3 2.1 3.7 7.1 4.9 0 –
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Endosome 0 1.9 0 0 1.5 0 0 0 0 0 0 2.0 0 0 –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Mitochondria 0 2.2 6.8 9.7 6.5 6.7 11.2 11.0 10.5 0 0 0 0 0 –
Nucleus -0.9 -3.3 -5.4 -5.0 -5.5 -3.7 -6.6 -6.9 -6.8 -0.4 -2.2 -7.6 -7.9 -4.3 –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nucleolus 0.3 0 1.5 1.3 2.8 3.1 3.8 4.8 3.4 0 0 0 0 0 –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Vacuole -1.0 2.2 3.0 -0.3 1.1 -0.4 0.7 1.0 -0.1 -1.4 1.1 4.0 5.2 0 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.2495 2.9385 2.339 2.135 1.7667 2.4954 3.5248 3.954 3.7425 3.5925 4.1562 3.8455 3.1036 3.5148 3.2292 3.0187 3.4323 3.3527
Actin 0.0168 0 0.0044 0.0264 0.067 0.0009 0.0401 0 0.0081 0.0234 0.0277 0.0009 0.0116 0 0.0045 0.0028 0.0045 0.0046
Bud 0.0003 0 0.0002 0.0002 0.0006 0.0001 0.0008 0 0.0003 0.0012 0.0005 0.0004 0.0002 0.0001 0.0001 0.0008 0.0002 0.0001
Bud Neck 0.0018 0.0001 0.007 0.0017 0.0014 0.0012 0.0105 0.0001 0.0049 0.001 0.0013 0.0017 0.0029 0.0002 0.0002 0.0009 0.0269 0.001
Bud Periphery 0.0009 0 0.0004 0.0004 0.001 0.0001 0.0015 0 0.0005 0.0036 0.0009 0.0008 0.0003 0 0.0001 0.0016 0.0003 0.0002
Bud Site 0.0052 0.0001 0.0034 0.0004 0.0011 0.0001 0.0028 0.0001 0.0011 0.0041 0.0018 0.0015 0.0008 0.0002 0.0002 0.0016 0.0012 0.0001
Cell Periphery 0.0006 0 0.0002 0.0001 0.0001 0 0.0004 0 0.0001 0.0006 0.0001 0.0001 0.0001 0 0 0.0004 0.0001 0
Cytoplasm 0.0081 0.0062 0.0037 0.0013 0.084 0.0015 0.0122 0.0009 0.0019 0.0011 0.0023 0.001 0.0081 0.006 0.0025 0.0082 0.0011 0.0004
Cytoplasmic Foci 0.006 0.0001 0.0012 0.0052 0.0056 0.0019 0.0122 0 0.002 0.0042 0.0021 0.0003 0.0156 0 0.0032 0.0176 0.0044 0.0008
Eisosomes 0.0002 0 0.0001 0.0002 0.0004 0 0.0003 0 0.0001 0.0004 0.0003 0 0.0001 0 0 0 0 0.0001
Endoplasmic Reticulum 0.003 0.0004 0.0006 0.0013 0.0028 0.0002 0.0076 0 0.0007 0.0018 0.002 0.0003 0.0029 0.0004 0.0008 0.0036 0.0003 0.0006
Endosome 0.0186 0.0003 0.0018 0.0071 0.0094 0.0042 0.0217 0 0.0014 0.0125 0.0138 0.0018 0.0317 0.0005 0.0064 0.0304 0.0066 0.002
Golgi 0.004 0 0.0005 0.003 0.004 0.0016 0.0044 0 0.001 0.004 0.0079 0.0003 0.003 0 0.0019 0.0072 0.0034 0.0008
Lipid Particles 0.0145 0 0.0008 0.0057 0.0041 0.0044 0.0082 0 0.0007 0.0193 0.0071 0.0015 0.0114 0 0.0068 0.0427 0.003 0.0025
Mitochondria 0.0112 0.0001 0.0006 0.0009 0.0011 0.0009 0.0044 0.0001 0.0026 0.0119 0.0032 0.0015 0.0024 0.0001 0.001 0.0087 0.0003 0.0044
None 0.0112 0.0005 0.0075 0.0028 0.0358 0.0002 0.0085 0 0.0039 0.001 0.0008 0.0002 0.0052 0.0001 0.0006 0.0012 0.0002 0.0003
Nuclear Periphery 0.0105 0.0083 0.0099 0.0275 0.0155 0.0048 0.0265 0.0015 0.0034 0.0186 0.0174 0.0068 0.0239 0.0062 0.0086 0.0117 0.0019 0.0062
Nucleolus 0.0074 0.0054 0.0059 0.0065 0.0141 0.0114 0.0088 0.0038 0.0037 0.0056 0.0079 0.007 0.0048 0.0033 0.0028 0.0078 0.0065 0.0062
Nucleus 0.8559 0.9696 0.9431 0.881 0.7375 0.9629 0.7987 0.9835 0.9585 0.8262 0.8917 0.9698 0.8471 0.9809 0.9558 0.7566 0.9347 0.9667
Peroxisomes 0.0027 0 0.0006 0.0022 0.0016 0.0011 0.007 0 0.0018 0.0194 0.0018 0.0004 0.0041 0 0.0015 0.0598 0.0009 0.0004
Punctate Nuclear 0.0165 0.0084 0.0053 0.0244 0.0112 0.002 0.0154 0.0098 0.0027 0.0354 0.0079 0.0026 0.0185 0.0013 0.0024 0.011 0.0027 0.0011
Vacuole 0.0026 0.0003 0.0019 0.0009 0.001 0.0003 0.0058 0.0001 0.0004 0.0025 0.0009 0.0007 0.003 0.0006 0.0003 0.0182 0.0007 0.0006
Vacuole Periphery 0.0019 0.0001 0.0009 0.0009 0.0006 0.0002 0.0023 0 0.0002 0.002 0.0008 0.0003 0.0022 0.0001 0.0003 0.0073 0.0001 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.5238 14.5939 21.6586 26.0985 8.7157 18.2359 24.5208 24.6051 25.2287 18.6862
Translational Efficiency 1.8818 2.2681 1.7585 0.9328 2.6683 1.8206 1.3692 1.6703 1.6997 1.5187

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2124 163 1996 1535 1501 1518 406 1083 3625 1681 2402 2618

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 867.16 988.46 1058.22 1170.68 819.41 919.65 1188.71 1185.42 847.39 926.32 1080.28 1176.78
Standard Deviation 111.30 145.00 151.48 174.70 116.54 590.00 164.25 174.83 115.91 562.85 161.31 174.91
Intensity Change Log 2 — 0.188884 0.287269 0.432977 — 0.166499 0.536739 0.532741 — 0.178052 0.413863 0.482309

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000172 0.001190 0.000647 0.000977 0.000358 0.000442 0.001951 0.001171 0.000249 0.000514 0.000868 0.001058
Bud Neck 0.004998 0.011225 0.018790 0.030367 0.004418 0.007076 0.011398 0.020057 0.004758 0.007478 0.017541 0.026102
Bud Site 0.000926 0.007248 0.002005 0.009097 0.001098 0.002245 0.004262 0.007404 0.000997 0.002730 0.002386 0.008397
Cell Periphery 0.000091 0.000102 0.000146 0.000144 0.000121 0.000116 0.000120 0.000177 0.000104 0.000114 0.000141 0.000158
Cytoplasm 0.009137 0.017532 0.012166 0.008217 0.012681 0.010890 0.006262 0.024743 0.010604 0.011534 0.011168 0.015054
Cytoplasmic Foci 0.000380 0.002162 0.000179 0.002036 0.001132 0.002693 0.000088 0.007873 0.000691 0.002642 0.000164 0.004450
Eisosomes 0.000012 0.000036 0.000029 0.000026 0.000016 0.000019 0.000049 0.000036 0.000013 0.000021 0.000032 0.000030
Endoplasmic Reticulum 0.002788 0.009353 0.004335 0.005167 0.003996 0.005169 0.008871 0.005535 0.003288 0.005574 0.005102 0.005319
Endosome 0.000256 0.000667 0.000317 0.005319 0.000401 0.002667 0.000379 0.014601 0.000316 0.002473 0.000327 0.009159
Golgi 0.000061 0.000245 0.000066 0.003870 0.000173 0.001752 0.000106 0.010234 0.000107 0.001606 0.000073 0.006503
Lipid Particles 0.000191 0.000487 0.000122 0.000190 0.000388 0.000663 0.000320 0.000493 0.000273 0.000646 0.000155 0.000315
Mitochondria 0.001399 0.002531 0.001499 0.008282 0.001348 0.002151 0.003257 0.015096 0.001378 0.002188 0.001796 0.011101
Mitotic Spindle 0.001130 0.017361 0.004393 0.036997 0.000552 0.004120 0.002390 0.055791 0.000891 0.005404 0.004055 0.044771
None 0.002426 0.002449 0.005230 0.004358 0.005404 0.004859 0.002569 0.004521 0.003659 0.004625 0.004780 0.004426
Nuclear Periphery 0.000983 0.000794 0.001114 0.003106 0.000939 0.001178 0.000627 0.001685 0.000965 0.001141 0.001031 0.002518
Nuclear Periphery Foci 0.000291 0.002032 0.000274 0.002290 0.000647 0.001224 0.000179 0.001674 0.000439 0.001302 0.000258 0.002035
Nucleolus 0.004887 0.005579 0.003674 0.003207 0.006904 0.006909 0.004223 0.009869 0.005722 0.006780 0.003767 0.005963
Nucleus 0.968753* 0.912507* 0.943038* 0.865105* 0.957901* 0.938737* 0.944364* 0.795254* 0.964260* 0.936193* 0.943262* 0.836209*
Peroxisomes 0.000247 0.000831 0.000100 0.000267 0.000279 0.000492 0.002269 0.003340 0.000260 0.000525 0.000467 0.001538
Vacuole 0.000732 0.005376 0.001752 0.007025 0.000950 0.004543 0.006072 0.014758 0.000822 0.004623 0.002482 0.010224
Vacuole Periphery 0.000141 0.000291 0.000125 0.003953 0.000291 0.002058 0.000244 0.005689 0.000203 0.001886 0.000145 0.004671

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.14 -19.45 -22.71 0.52 -8.85 -1.17 -9.04 -16.86 -16.28 1.12 -5.60 -17.58 -27.20 -15.76 -8.45
Bud Neck -3.49 -16.13 -20.32 -11.08 -10.60 -3.54 -9.39 -17.60 -15.94 -10.29 -4.48 -18.22 -26.81 -23.17 -13.58
Bud Site -1.73 -3.78 -7.06 -0.11 -5.88 -1.42 -3.22 -10.37 -8.26 -5.18 -2.31 -5.23 -11.79 -7.03 -9.54
Cell Periphery -1.38 -2.09 -3.11 -1.22 -1.48 0.33 -0.78 -3.80 -4.03 -3.15 -0.80 -2.08 -4.66 -3.54 -3.15
Cytoplasm -1.62 -0.44 0.74 1.81 1.21 0.77 2.70 -1.65 -2.43 -4.01 -0.63 1.06 -0.82 -0.02 -1.85
Cytoplasmic Foci -1.46 2.89 -0.79 1.31 -2.54 -1.84 2.22 -0.68 1.30 -3.46 -3.17 2.98 -0.95 2.66 -4.27
Eisosomes -4.81 -15.95 -20.18 1.19 -4.35 -1.98 -12.37 -15.74 -14.36 1.30 -6.12 -19.17 -24.79 -14.05 -5.33
Endoplasmic Reticulum -5.93 -8.96 -10.97 3.92 -2.40 -2.87 -9.58 -7.09 -2.59 5.07 -6.51 -11.25 -12.88 -0.44 -0.82
Endosome -3.04 -2.42 -3.27 -1.57 -3.05 -3.41 -1.00 -3.69 -0.67 -3.52 -3.69 -1.37 -4.93 0.00 -4.77
Golgi -1.63 -2.41 -2.45 -2.00 -2.39 -2.62 -0.06 -2.47 -0.47 -2.48 -2.78 -0.02 -3.47 -0.11 -3.48
Lipid Particles -3.04 1.51 -1.32 2.81 -4.43 -1.32 0.35 -1.16 0.61 -2.77 -2.63 1.75 -1.54 2.11 -6.67
Mitochondria -0.89 -0.73 -4.59 -1.76 -5.15 -1.19 -1.56 -3.26 -2.73 -2.11 -1.56 -1.39 -5.49 -4.21 -5.39
Mitotic Spindle -1.73 -3.66 -9.34 -2.11 -7.63 -3.18 -2.05 -12.31 -11.44 -10.01 -3.30 -4.42 -15.33 -12.92 -12.98
None -0.43 -3.54 -5.85 -4.38 -1.61 0.47 2.01 -2.42 -2.97 -5.35 -1.27 -1.04 -5.48 -2.20 -3.97
Nuclear Periphery -0.17 -0.70 -6.67 -6.75 -5.03 -0.52 -0.41 -4.47 -7.62 -11.66 -0.72 -0.77 -7.76 -7.83 -6.87
Nuclear Periphery Foci -1.25 0.47 -3.42 1.01 -3.56 -1.24 -0.31 -3.60 -2.19 -1.72 -2.22 0.54 -4.96 -0.15 -5.07
Nucleolus -0.87 0.15 -7.76 -6.76 -7.76 -0.09 2.30 -8.78 -8.90 -9.80 -1.62 1.76 -11.68 -10.57 -12.37
Nucleus 4.38 9.81 19.20 3.12 13.93 3.74 4.44 20.49 17.48 15.06 6.54 9.96 27.81 18.37 21.65
Peroxisomes -2.07 1.43 -0.06 2.13 -4.11 -1.25 -0.97 -1.85 -1.27 0.05 -1.91 -0.06 -1.77 -0.12 -1.41
Vacuole -2.94 -6.49 -8.48 0.51 -6.88 -4.30 -5.82 -9.59 -7.27 -3.62 -5.39 -8.28 -12.74 -6.76 -9.48
Vacuole Periphery -1.41 0.35 -2.75 -2.28 -2.79 -2.97 0.52 -2.18 1.24 -2.46 -3.20 1.02 -3.50 1.12 -3.79
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Mig2

Mig2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mig2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available