Standard name
Human Ortholog
Description Kinesin-related antiparallel sliding motor protein; involved in mitotic spindle positioning; sliding activity promotes bipolar spindle assembly and maintenance of genome stability; inhibits spindle elongation, destabilizing late anaphase spindle microtubules that polymerize beyond the midzone
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0.05 0 0.05 0.05 0.05
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0.05 0 0.07 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.27 0.38 0.38 0.36 0.25 0.27 0.18 – 0.1 0.13 0.11 0.09 0.36 0.38 0.45 0.17 0.18 0.11 0.17 0.19 0.19 0.25 0.2 0.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0.46 0.31 0.19 0.24 0.27 0.23 0.18 – 0.1 0.06 0.07 0.1 0.45 0.49 0.38 0.37 0.47 0.49 0.31 0.22 0.19 0.19 0.21 0.19
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.13 0 0.07 0 0.21 0.28 – 0.58 0.55 0.61 0.46 0 0 0 0.05 0 0 0 0.07 0.12 0.1 0.09 0.07
Nucleus 0 0 0 0 0 0.05 0 – 0.07 0.08 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.12 0.09 0 0.07 0.1 0.09 0.17 – 0.16 0.13 0.15 0.12 0.06 0.09 0.1 0.16 0.23 0.16 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.1 0.08 0.23 0.17 0.38 0.16 0.27 – 0.18 0.19 0.23 0.32 0.05 0.09 0 0.2 0.27 0.27 0.31 0.28 0.31 0.15 0.23 0.3
Vac/Vac Membrane 0.19 0.21 0.17 0.14 0.11 0.13 0.11 – 0 0.07 0.05 0.07 0.19 0.21 0.18 0.32 0.21 0.34 0 0.05 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 3 13 5 7 3 2 – 0 1 0 0 1 0 0 6 4 3 4 6 3 9 17 17
Bud 2 8 2 2 5 6 10 – 11 13 11 19 3 2 2 2 1 0 12 19 5 9 16 21
Bud Neck 0 0 5 1 3 1 2 – 8 7 3 11 0 0 0 0 0 0 3 9 4 6 4 7
Bud Site 0 0 0 1 3 4 15 – 16 13 22 9 1 0 1 0 1 0 – – – – – –
Cell Periphery 0 1 0 0 0 1 0 – 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 78 126 89 74 80 75 83 – 35 49 35 31 99 150 157 25 23 13 56 78 62 51 64 84
Endoplasmic Reticulum 6 5 8 5 2 2 5 – 1 0 2 0 1 1 2 8 1 3 0 0 3 3 11 6
Endosome 133 103 44 49 87 65 85 – 34 21 23 34 126 195 133 55 61 57 106 87 63 38 68 80
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 3 3 5 2 4 1 1 3 3
Mitochondria 15 44 4 14 11 60 129 – 203 207 194 162 11 7 9 8 5 2 13 27 41 21 27 28
Nucleus 4 2 1 6 6 15 13 – 25 28 14 18 3 1 4 1 3 1 2 7 1 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 1 2 0 0 1 0 1 0 0 2 0 1 1 1 2
Nucleolus 34 30 5 15 32 26 77 – 55 48 47 41 18 35 36 24 30 18 4 8 3 1 0 3
Peroxisomes 3 2 0 1 4 8 6 – 3 2 3 4 4 19 12 1 2 2 4 1 2 6 3 3
SpindlePole 29 26 53 35 123 44 125 – 63 70 74 112 13 35 11 30 35 31 107 111 103 31 75 125
Vac/Vac Membrane 55 69 39 29 37 36 51 – 14 25 15 24 52 84 62 47 27 39 5 21 11 9 10 14
Unique Cell Count 290 336 235 204 326 282 465 349 373 317 352 277 398 346 149 130 116 340 402 335 207 329 422
Labelled Cell Count 367 419 263 237 400 346 603 468 485 445 468 332 531 429 211 196 174 340 402 335 207 329 422


Microtubule

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.3 5.9 6.5 6.1 6.7 5.3 5.4 – 4.5 4.2 4.1 4.6 6.9 6.8 6.8 9.9 11.1 10.1 6.1 6.4 6.6
Std Deviation (1e-4) 1.5 1.4 1.2 1.2 1.5 1.2 1.2 – 0.9 0.9 1.2 1.0 2.5 1.8 2.0 2.2 2.5 1.9 1.5 2.0 1.8
Intensity Change (Log2) – – – -0.1 0.05 -0.29 -0.29 – -0.54 -0.62 -0.67 -0.5 0.08 0.05 0.06 0.59 0.76 0.63 -0.11 -0.03 0.02


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.6 -2.1 -2.9 -4.4 – 0 0 0 0 -3.6 0 -4.4 -0.7 -1.1 -1.2
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 2.8 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.3 -3.4 -2.7 -5.8 – -8.1 -7.1 -7.5 -8.6 -0.5 0 1.8 -4.4 -4.0 -5.2
Endoplasmic Reticulum -0.6 0 0 0 – 0 0 0 0 0 0 0 0.9 0 0
Endosome 1.4 2.2 1.2 -0.1 – 0 0 0 0 6.4 7.6 5.1 4.0 5.7 5.9
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.7 1.2 6.7 8.3 – 0 0 0 0 1.5 0 0.7 0 0 0
Nucleus 0 0 3.2 0 – 3.9 4.0 2.9 3.1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 2.6 3.6 3.4 5.6 – 0 0 0 0 2.4 3.3 3.8 5.1 6.5 4.8
Peroxisomes 0 0 0 0 – 0 0 0 0 0 3.4 0 0 0 0
SpindlePole -1.4 3.8 -2.0 1.2 – 0 0 0 0 -6.0 -4.8 -7.3 -0.6 0.9 0.9
Vacuole -0.7 -1.8 -1.2 -2.1 – -5.2 -3.9 -4.6 -3.7 0.6 1.4 0.4 3.4 1.0 3.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.0693 5.0264 4.9396 4.8579 4.7905 4.5785 2.1939 3.3394 3.3116 3.0704 2.8987 3.1683 1.8752 3.3549 3.0601 3.4048 2.9302 2.8799
Actin 0.0399 0.0138 0.0062 0.0373 0.0127 0.0069 0.0133 0.0163 0.0245 0.0062 0.022 0.0237 0.0147 0.0049 0.014 0.0295 0.022 0.0133
Bud 0.0011 0.0018 0.0007 0.0019 0.0004 0.0004 0.0011 0.0008 0.0009 0.0005 0.0014 0.0007 0.0007 0.0012 0.0004 0.0004 0.0015 0.0006
Bud Neck 0.0098 0.0086 0.0069 0.0089 0.037 0.0718 0.0024 0.0033 0.0053 0.0025 0.0048 0.0342 0.0037 0.0036 0.0053 0.0016 0.0059 0.0349
Bud Periphery 0.0016 0.0015 0.0012 0.003 0.0004 0.0007 0.001 0.0005 0.001 0.001 0.0037 0.0008 0.0007 0.0006 0.0003 0.0003 0.0013 0.0007
Bud Site 0.0244 0.0371 0.0114 0.0171 0.0027 0.0018 0.0066 0.0137 0.0203 0.0017 0.0033 0.0022 0.0037 0.0166 0.0077 0.0012 0.0032 0.0023
Cell Periphery 0.0005 0.0004 0.0002 0.0015 0.0001 0.0002 0.0002 0.0001 0.0003 0 0.0001 0.0002 0.0001 0.0001 0.0001 0 0.0002 0.0002
Cytoplasm 0.0814 0.0856 0.0285 0.0086 0.0075 0.0616 0.1123 0.1218 0.0451 0.0065 0.0406 0.0701 0.1611 0.1048 0.0455 0.0374 0.0278 0.0997
Cytoplasmic Foci 0.1905 0.1095 0.1379 0.1152 0.2592 0.1715 0.1657 0.1164 0.1387 0.1311 0.3043 0.1531 0.1827 0.1499 0.1051 0.0913 0.2516 0.1741
Eisosomes 0.0004 0.0002 0.0001 0.0012 0.0001 0.0001 0.0002 0 0.0002 0 0.0001 0.0001 0.0003 0 0.0001 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0076 0.0045 0.0012 0.0067 0.0011 0.0044 0.009 0.0048 0.0046 0.0004 0.0039 0.0058 0.008 0.0022 0.0019 0.0007 0.0027 0.0044
Endosome 0.0822 0.0373 0.015 0.0474 0.0743 0.0604 0.0994 0.0603 0.0369 0.0165 0.1034 0.1057 0.0849 0.0362 0.0214 0.0226 0.1225 0.0615
Golgi 0.0173 0.0136 0.0053 0.0145 0.0409 0.0163 0.0344 0.011 0.0132 0.0114 0.0492 0.0337 0.0151 0.0093 0.0074 0.0124 0.0715 0.0199
Lipid Particles 0.0522 0.0356 0.0105 0.0414 0.1607 0.0771 0.0519 0.019 0.0142 0.0299 0.035 0.0677 0.0514 0.0236 0.0126 0.0462 0.0965 0.0404
Mitochondria 0.0056 0.0048 0.0026 0.0067 0.0038 0.0196 0.0139 0.0017 0.0153 0.0066 0.0151 0.0129 0.0049 0.0013 0.0071 0.001 0.0179 0.007
None 0.0533 0.0281 0.0091 0.0175 0.0015 0.019 0.0208 0.0094 0.0031 0.0082 0.0156 0.0062 0.0267 0.0091 0.0088 0.0007 0.0021 0.003
Nuclear Periphery 0.012 0.0095 0.0028 0.0077 0.0181 0.0169 0.0262 0.0187 0.0214 0.0246 0.0119 0.03 0.0227 0.0129 0.0073 0.0028 0.0056 0.0326
Nucleolus 0.0039 0.0277 0.0258 0.005 0.0049 0.0166 0.0059 0.0289 0.0079 0.0205 0.0155 0.0149 0.0024 0.0218 0.0087 0.0044 0.0029 0.0147
Nucleus 0.0287 0.0703 0.0442 0.0071 0.0043 0.0388 0.0289 0.0507 0.0317 0.0182 0.0204 0.0645 0.0249 0.1222 0.0506 0.0388 0.0045 0.0868
Peroxisomes 0.0435 0.0344 0.0259 0.0436 0.0965 0.0562 0.0406 0.036 0.016 0.0397 0.1637 0.0658 0.0444 0.0343 0.0194 0.0189 0.2372 0.0777
Punctate Nuclear 0.3343 0.4721 0.6631 0.6022 0.2721 0.3563 0.3601 0.4828 0.5956 0.6733 0.1811 0.3004 0.3434 0.4427 0.6697 0.6889 0.1187 0.3218
Vacuole 0.0075 0.003 0.0012 0.0043 0.001 0.0025 0.0047 0.0032 0.0023 0.0006 0.0029 0.0051 0.0024 0.0019 0.0055 0.0007 0.0031 0.0032
Vacuole Periphery 0.0021 0.0006 0.0002 0.0014 0.0006 0.0011 0.0015 0.0007 0.0016 0.0005 0.0018 0.0021 0.0011 0.0005 0.0012 0.0002 0.0012 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.7826 22.0283 14.227 13.1396 18.9328 14.1384 25.7786 20.6002 14.6039 20.6944
Translational Efficiency 0.5565 0.5879 0.5379 0.5201 0.604 0.702 0.5322 0.535 0.5476 0.5401

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2473 1753 263 558 1311 1350 1825 583 3784 3103 2088 1141

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 761.40 906.75 1117.63 1033.18 839.51 847.19 974.45 1050.45 788.46 880.84 992.48 1042.00
Standard Deviation 100.70 147.44 148.18 149.52 122.82 133.91 140.01 145.47 115.04 144.76 148.85 147.71
Intensity Change Log 2 — 0.252050 0.553716 0.440365 — 0.013138 0.215041 0.323388 — 0.131707 0.386046 0.380207

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000479 0.001447 0.000521 0.001258 0.000909 0.001988 0.000972 0.001512 0.000628 0.001682 0.000915 0.001388
Bud Neck 0.016728 0.007054 0.002027 0.002835 0.009055 0.014227 0.004638 0.002894 0.014070 0.010175 0.004309 0.002865
Bud Site 0.007047 0.013728 0.003667 0.019138 0.009719 0.011691 0.009458 0.020120 0.007973 0.012842 0.008729 0.019640
Cell Periphery 0.000109 0.000103 0.000026 0.000032 0.000151 0.000166 0.000044 0.000038 0.000124 0.000131 0.000042 0.000035
Cytoplasm 0.155622* 0.136450* 0.002171 0.006013 0.187662* 0.151691* 0.019825 0.003502 0.166723* 0.143081* 0.017602 0.004730
Cytoplasmic Foci 0.268036* 0.098167 0.001809 0.007898 0.217718* 0.190461* 0.013086 0.006645 0.250603* 0.138321 0.011666 0.007258
Eisosomes 0.000070 0.000038 0.000007 0.000008 0.000067 0.000080 0.000017 0.000008 0.000069 0.000056 0.000016 0.000008
Endoplasmic Reticulum 0.000868 0.001232 0.000697 0.000310 0.001868 0.001563 0.000689 0.000261 0.001214 0.001376 0.000690 0.000285
Endosome 0.021105 0.016891 0.001782 0.003572 0.022842 0.041191 0.006519 0.003986 0.021707 0.027463 0.005923 0.003783
Golgi 0.011874 0.007736 0.000235 0.001851 0.010638 0.015818 0.001660 0.002160 0.011446 0.011252 0.001481 0.002009
Lipid Particles 0.058946 0.015246 0.001358 0.001513 0.042608 0.031210 0.002533 0.000722 0.053285 0.022191 0.002385 0.001109
Mitochondria 0.018908 0.006542 0.000214 0.003448 0.004286 0.018052 0.002617 0.004219 0.013842 0.011550 0.002314 0.003842
Mitotic Spindle 0.294984* 0.599269* 0.963453* 0.939858* 0.353844* 0.341294* 0.888467* 0.942147* 0.315377* 0.487034* 0.897912* 0.941028*
None 0.012847 0.007023 0.000170 0.000061 0.008398 0.008681 0.002003 0.000062 0.011306 0.007745 0.001772 0.000061
Nuclear Periphery 0.001869 0.001241 0.000546 0.000182 0.001724 0.001561 0.000543 0.000144 0.001818 0.001381 0.000544 0.000162
Nuclear Periphery Foci 0.016138 0.019753 0.004707 0.001400 0.035386 0.015146 0.006698 0.001031 0.022806 0.017748 0.006447 0.001212
Nucleolus 0.023725 0.011020 0.002633 0.000425 0.014290 0.016580 0.004586 0.000318 0.020456 0.013439 0.004340 0.000370
Nucleus 0.038076 0.024871 0.006747 0.001332 0.038376 0.063207 0.018195 0.000477 0.038180 0.041549 0.016753 0.000895
Peroxisomes 0.043398 0.020081 0.003130 0.006104 0.028836 0.040118 0.012366 0.006262 0.038353 0.028798 0.011203 0.006185
Vacuole 0.008503 0.011313 0.003959 0.002548 0.011003 0.033023 0.004794 0.003111 0.009369 0.020758 0.004689 0.002835
Vacuole Periphery 0.000667 0.000796 0.000142 0.000217 0.000619 0.002252 0.000288 0.000381 0.000651 0.001429 0.000269 0.000301

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.11 -3.53 -3.14 -0.43 1.17 -1.58 -2.26 -1.40 0.27 -0.31 -3.19 -4.90 -3.20 -0.06 -0.08
Bud Neck 7.40 4.23 8.32 2.09 2.24 -3.94 1.87 4.82 7.79 3.53 3.00 6.86 10.26 7.05 3.78
Bud Site -5.50 -3.46 -4.62 -2.34 -1.88 -2.26 -3.13 -4.16 -3.29 -2.82 -6.17 -5.92 -6.46 -3.93 -3.47
Cell Periphery -0.58 -1.54 4.02 3.87 3.49 -0.21 8.36 9.31 5.49 2.82 -0.90 6.53 8.92 6.89 3.44
Cytoplasm -0.37 25.87 25.60 21.28 0.25 1.85 18.86 22.27 21.76 6.82 0.60 27.68 34.25 30.35 6.85
Cytoplasmic Foci 25.73 49.88 48.77 22.16 -1.78 3.35 30.32 31.07 30.27 2.93 21.37 56.35 57.76 36.53 2.68
Eisosomes 7.60 2.09 17.34 10.51 3.71 -3.12 10.37 17.56 19.74 7.54 2.49 11.88 25.24 21.32 8.44
Endoplasmic Reticulum -5.08 -4.56 -0.27 2.13 4.16 0.71 0.44 6.28 5.22 6.02 -3.56 -5.28 2.77 4.84 6.18
Endosome 1.54 14.53 14.27 11.29 0.47 -6.41 9.82 10.86 14.01 2.36 -4.72 14.34 17.62 17.59 2.99
Golgi 3.01 13.79 8.14 5.02 -1.16 -3.33 9.06 6.88 7.92 -0.76 -0.55 14.95 10.90 9.30 -0.71
Lipid Particles 14.07 19.31 20.75 10.36 2.13 2.42 13.57 14.56 13.32 5.02 12.30 24.20 25.37 16.97 3.90
Mitochondria 6.99 13.48 6.31 1.38 -1.76 -6.73 2.15 -0.13 5.55 -1.20 1.05 10.46 6.26 4.85 -1.36
Mitotic Spindle -23.04* -29.27* -56.54* -27.77* -3.55 0.72 -37.46* -43.63* -44.15* -8.78 -16.59 -58.18 -73.69 -48.48* -10.14
None 5.26 16.15 16.62 11.94 3.84 0.14 9.10 14.31 9.79 3.95 4.33 14.14 20.96 15.23 4.09
Nuclear Periphery 1.22 1.65 9.51 6.15 4.98 0.22 3.80 8.47 7.91 8.42 1.08 5.20 12.84 9.75 9.27
Nuclear Periphery Foci -1.65 1.95 13.64 13.86 4.87 6.83 9.70 15.20 10.37 7.96 3.14 8.29 20.20 17.24 9.19
Nucleolus 9.23 11.86 20.16 12.13 2.85 0.32 7.34 12.87 12.70 8.83 7.61 14.84 23.71 17.48 9.60
Nucleus 1.46 0.20 13.24 10.45 3.95 -4.71 0.37 12.53 13.90 10.34 -3.08 -0.23 18.69 17.43 11.09
Peroxisomes 8.20 14.23 14.57 6.47 -0.36 -3.86 5.81 8.36 10.90 3.26 3.27 12.43 16.83 12.39 3.64
Vacuole -4.75 -3.84 -1.19 0.86 3.14 -7.63 -1.53 0.74 6.93 1.75 -9.18 -4.55 -0.71 5.38 2.64
Vacuole Periphery -1.22 2.87 3.14 2.95 0.39 -5.89 2.25 0.69 5.58 -0.41 -5.41 3.69 2.14 6.01 0.05
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Kinesin-related antiparallel sliding motor protein; involved in mitotic spindle positioning; sliding activity promotes bipolar spindle assembly and maintenance of genome stability; inhibits spindle elongation, destabilizing late anaphase spindle microtubules that polymerize beyond the midzone
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Kip3

Kip3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kip3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available