Standard name
Human Ortholog
Description Protein of unknown function; similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.07 0.08 0.13 0.06 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0.06 0 0.06 0 0.07 0 0 0.06
Bud 0 0.06 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0 0 0 0 0 0
Cytoplasm 0.43 0.29 0.24 0.3 0.29 0.2 0.12 0.13 0.09 0.07 0.07 0.08 0.46 0.3 0.11 0.54 0.45 0.49 0.23 0.1 0 0.07 0.05 0
Endoplasmic Reticulum 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0.13 0 0.07 0 0 0 0 0 0 0 0 0
Endosome 0.15 0.15 0.27 0.21 0.18 0.22 0.22 0.16 0 0.11 0.1 0.09 0.13 0.29 0.23 0.21 0.18 0.17 0.27 0.21 0.2 0.11 0.13 0.1
Golgi 0 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0.1 0.18 0 0.08 0 0 0.06 0.07 0.07 0.09 0.11
Mitochondria 0.14 0.33 0.05 0.26 0.28 0.31 0.41 0.37 0.74 0.68 0.76 0.7 0.15 0.17 0.34 0.07 0.06 0 0.19 0.38 0.42 0.4 0.31 0.39
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.1 0.06
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0.05
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.2 0.07 0 0 0 0 0 0 0 0 0 0 0.05 0.1 0.14 0.11 0 0 0.07 0 0 0
Vac/Vac Membrane 0.24 0.19 0.14 0.18 0.21 0.34 0.31 0.32 0.18 0.19 0.16 0.16 0.18 0.11 0.13 0.14 0.24 0.29 0.05 0.09 0 0.09 0.1 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 13 27 48 16 11 5 4 15 4 3 10 6 2 7 3 14 18 15 15 18 35 2 9 15
Bud 5 20 14 8 12 9 16 18 19 13 10 21 0 5 1 4 5 4 7 6 8 6 6 5
Bud Neck 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 3 7 5 2 2 3
Bud Site 0 2 1 0 1 0 2 3 2 0 4 5 0 0 0 0 0 1 – – – – – –
Cell Periphery 2 12 14 13 3 2 7 5 3 2 7 11 0 3 0 15 20 19 0 0 3 0 0 0
Cytoplasm 76 104 85 85 74 91 65 68 46 33 39 50 18 35 14 204 137 189 59 45 22 13 12 10
Endoplasmic Reticulum 13 19 7 9 7 12 9 7 9 10 10 22 5 2 9 15 10 11 6 4 7 1 1 3
Endosome 27 53 97 60 46 99 117 85 22 48 53 59 5 33 30 80 56 64 69 99 107 21 33 26
Golgi 4 9 22 14 7 13 11 10 2 11 8 11 0 12 24 10 23 11 10 28 40 14 22 29
Mitochondria 25 118 18 72 73 140 215 198 371 308 423 444 6 19 45 28 17 7 48 176 229 78 80 104
Nucleus 1 1 1 2 4 2 5 18 16 7 8 5 1 0 0 0 2 1 1 0 1 9 24 15
Nuclear Periphery 1 2 0 0 1 0 1 3 3 7 3 7 0 0 1 0 0 0 1 2 1 0 1 2
Nucleolus 1 1 0 4 3 1 7 9 9 7 8 10 0 0 1 4 2 3 1 0 0 9 17 12
Peroxisomes 0 3 4 1 0 0 6 0 1 1 3 4 0 1 6 7 1 4 0 6 10 3 5 5
SpindlePole 2 14 73 21 10 16 21 24 8 18 14 21 0 4 6 38 44 42 9 16 39 6 11 6
Vac/Vac Membrane 42 69 49 51 53 154 162 172 92 85 90 103 7 13 17 52 72 111 14 40 11 18 24 22
Unique Cell Count 177 359 360 282 258 455 526 539 504 456 557 633 39 115 131 379 305 384 260 465 547 194 258 271
Labelled Cell Count 212 454 434 356 306 544 648 636 607 553 690 779 44 134 157 471 407 482 260 465 547 194 258 271


Cytoplasm, Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.7 5.9 8.1 7.8 6.7 7.2 6.9 6.9 6.1 6.4 6.1 6.2 7.5 7.9 7.2 8.0 10.3 10.7 9.0 9.4 9.3
Std Deviation (1e-4) 1.5 1.0 1.2 1.3 1.5 1.2 1.4 1.2 1.3 1.0 1.1 1.1 1.2 1.4 1.3 1.6 1.9 2.1 2.5 3.0 2.3
Intensity Change (Log2) – – – -0.05 -0.27 -0.16 -0.22 -0.22 -0.41 -0.34 -0.41 -0.39 -0.11 -0.03 -0.16 -0.02 0.35 0.41 0.17 0.22 0.2


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.2 -3.8 -7.0 -7.8 -6.1 -7.6 -7.4 -7.0 -8.3 0 -2.1 -3.5 -4.7 -3.2 -4.6
Bud -0.7 0.5 -1.6 -0.7 -0.4 -0.1 -0.8 -1.9 -0.5 0 0 0 -2.5 -1.7 -2.5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.5 -2.0 -3.5 -2.5 -3.0 -3.4 -3.5 -2.6 -2.1 0 0 0 0 1.6 0.7
Cytoplasm 1.9 1.4 -1.2 -4.4 -4.3 -5.9 -6.6 -7.2 -6.9 3.1 1.5 -3.2 8.4 5.8 7.2
Endoplasmic Reticulum 1.0 0.6 0.7 -0.3 -0.8 -0.2 0.2 -0.2 1.4 0 0 0 1.6 1.1 0.8
Endosome -1.7 -2.6 -1.7 -1.6 -4.1 -9.5 -6.1 -7.0 -7.3 -1.9 0.4 -0.9 -1.9 -2.6 -3.4
Golgi -0.6 -2.0 -2.3 -3.1 -3.4 -5.0 -2.7 -3.9 -3.7 0 1.6 4.1 -2.3 0.7 -2.1
Mitochondria 7.4 8.1 9.2 11.9 10.9 20.0 18.1 21.0 19.8 0 4.0 8.6 1.3 0.3 -2.4
Nucleus 0 0 0 0 3.1 3.0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0.8 0 0
SpindlePole -4.6 -5.9 -7.6 -7.7 -7.5 -9.3 -7.4 -9.0 -8.8 -3.1 -4.3 -4.2 -3.9 -2.0 -3.5
Vacuole 1.6 2.3 6.6 5.9 6.2 1.8 1.9 1.1 1.1 0.7 -0.6 -0.2 0 3.3 5.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0601 7.8416 7.1517 6.7803 6.5161 7.1758 9.7681 11.2126 11.4592 10.3846 10.3395 10.5363 8.6469 9.5168 9.0064 8.9995 8.5121 9.0174
Actin 0.0513 0.0225 0.0557 0.0212 0.1199 0.0214 0.054 0.0279 0.1319 0.0749 0.0373 0.0578 0.014 0.0098 0.0208 0.0153 0.0268 0.0177
Bud 0.0036 0.0046 0.0118 0.0064 0.006 0.0035 0.002 0.0081 0.0141 0.0089 0.0086 0.0085 0.0037 0.0057 0.0055 0.0182 0.0072 0.0029
Bud Neck 0.0037 0.0025 0.0044 0.0165 0.0022 0.0042 0.0034 0.0017 0.0027 0.0024 0.0011 0.0061 0.0034 0.0018 0.0023 0.0024 0.0037 0.0058
Bud Periphery 0.0053 0.0039 0.0136 0.0085 0.0041 0.0047 0.0019 0.0049 0.0231 0.0114 0.0075 0.0063 0.0053 0.0037 0.0056 0.02 0.0119 0.0033
Bud Site 0.0142 0.026 0.0242 0.0084 0.0051 0.0028 0.0175 0.0302 0.0468 0.0145 0.0139 0.0049 0.0084 0.0224 0.0084 0.0062 0.0087 0.0026
Cell Periphery 0.0038 0.0014 0.0026 0.0008 0.0004 0.0009 0.0003 0.0007 0.0026 0.0016 0.0003 0.0007 0.0012 0.0006 0.0012 0.001 0.0007 0.0005
Cytoplasm 0.1487 0.3168 0.2413 0.2456 0.233 0.2332 0.0845 0.324 0.2845 0.2226 0.1186 0.2147 0.1888 0.3646 0.3044 0.35 0.2182 0.2825
Cytoplasmic Foci 0.106 0.1695 0.1076 0.1622 0.1365 0.1197 0.1717 0.1587 0.1279 0.0369 0.1089 0.1386 0.1315 0.1409 0.1266 0.1374 0.1244 0.1342
Eisosomes 0.0005 0.0002 0.0006 0.0003 0.0003 0.0004 0.0002 0.0001 0.0005 0.001 0.0002 0.0004 0.0003 0.0001 0.0003 0.0002 0.0001 0.0001
Endoplasmic Reticulum 0.0219 0.009 0.0109 0.006 0.0078 0.0149 0.0071 0.0072 0.0168 0.0078 0.0047 0.0095 0.0235 0.0087 0.0115 0.0093 0.0114 0.0177
Endosome 0.2586 0.1646 0.1581 0.1585 0.2427 0.1677 0.145 0.1609 0.114 0.099 0.2175 0.1937 0.2878 0.2106 0.184 0.1703 0.2478 0.2407
Golgi 0.1323 0.1386 0.122 0.1253 0.1444 0.1465 0.1319 0.1366 0.1413 0.223 0.1448 0.1776 0.12 0.1132 0.1106 0.0675 0.1743 0.1311
Lipid Particles 0.0161 0.0038 0.0054 0.0127 0.0069 0.0044 0.0166 0.0111 0.0046 0.0011 0.001 0.0031 0.006 0.0026 0.0023 0.0009 0.0027 0.0017
Mitochondria 0.1445 0.0895 0.2067 0.1873 0.0365 0.2399 0.0621 0.087 0.0462 0.275 0.2459 0.1361 0.1411 0.0845 0.1799 0.1689 0.0993 0.1146
None 0.0158 0.0027 0.0051 0.002 0.0213 0.0014 0.03 0.0015 0.0044 0.0016 0.0008 0.0012 0.0042 0.002 0.0025 0.0017 0.0019 0.0016
Nuclear Periphery 0.0127 0.0014 0.003 0.0023 0.0022 0.0013 0.0128 0.0013 0.0012 0.0012 0.0005 0.0023 0.0115 0.0026 0.0041 0.0007 0.0048 0.0058
Nucleolus 0.0006 0.0006 0.0007 0.0006 0.0002 0.0002 0.0174 0.0002 0.0001 0.0001 0.0001 0.0003 0.0004 0.0002 0.0002 0.0001 0.0009 0.0001
Nucleus 0.0088 0.0019 0.002 0.0017 0.0014 0.0014 0.1069 0.0011 0.0009 0.0009 0.0005 0.0016 0.0037 0.0019 0.0032 0.0012 0.0024 0.0031
Peroxisomes 0.0216 0.0263 0.0108 0.0212 0.0157 0.0204 0.0385 0.0242 0.0306 0.0116 0.0826 0.0232 0.0222 0.0105 0.0143 0.0146 0.0187 0.0191
Punctate Nuclear 0.0036 0.0012 0.0016 0.0046 0.0023 0.0007 0.0844 0.0035 0.0009 0.0002 0.0003 0.002 0.0028 0.0007 0.0017 0.0005 0.0006 0.0007
Vacuole 0.0182 0.0102 0.0079 0.0051 0.0076 0.0061 0.0085 0.0058 0.0032 0.0017 0.0022 0.007 0.013 0.0093 0.0072 0.0085 0.0261 0.0083
Vacuole Periphery 0.0082 0.0029 0.0039 0.0027 0.0035 0.0043 0.0034 0.0035 0.0017 0.0027 0.0026 0.0044 0.007 0.0036 0.0034 0.005 0.0073 0.0059

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 63.6335 53.4714 56.5623 61.1709 62.7027 55.9665 61.5419 75.6976 66.2612 68.8794
Translational Efficiency 1.6072 1.684 1.4266 1.4384 1.3756 1.6263 1.6775 1.2419 1.4777 1.4589

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
207 1099 2875 1531 1863 2516 2714 1896 2070 3615 5589 3427

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 723.67 970.73 1221.52 1218.20 852.83 1067.83 1167.19 1282.56 839.91 1038.31 1195.14 1253.81
Standard Deviation 99.11 153.38 172.71 197.56 117.40 142.82 168.92 202.88 122.02 152.78 173.02 203.06
Intensity Change Log 2 — 0.423738 0.755274 0.751347 — 0.324352 0.452709 0.588696 — 0.370825 0.599507 0.665641

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000539 0.004039 0.003843 0.027950 0.002149 0.003072 0.005391 0.017518 0.001988 0.003366 0.004595 0.022178
Bud Neck 0.012445 0.008036 0.024493 0.005149 0.008669 0.010126 0.014362 0.004419 0.009047 0.009491 0.019573 0.004745
Bud Site 0.012982 0.108640* 0.065796 0.161023* 0.040081 0.053122 0.123882* 0.167732* 0.037371 0.070000 0.094002 0.164735*
Cell Periphery 0.000472 0.000251 0.000091 0.000430 0.000308 0.000177 0.000163 0.000392 0.000325 0.000199 0.000126 0.000409
Cytoplasm 0.003652 0.074979 0.493315* 0.072249 0.055766 0.048336 0.130847* 0.113013* 0.050554 0.056436 0.317302* 0.094802
Cytoplasmic Foci 0.056434 0.198586* 0.059144 0.096192 0.260791* 0.169294 0.103078 0.107778 0.240355* 0.178199 0.080478 0.102602
Eisosomes 0.000080 0.000070 0.000024 0.000097 0.000120 0.000080 0.000039 0.000075 0.000116 0.000077 0.000032 0.000084
Endoplasmic Reticulum 0.001415 0.001320 0.001559 0.001179 0.003251 0.000638 0.000953 0.000777 0.003068 0.000846 0.001265 0.000956
Endosome 0.086526 0.114202 0.013263 0.091445 0.112997 0.128526 0.096339 0.074993 0.110350 0.124171 0.053604 0.082343
Golgi 0.097275 0.181161* 0.013165 0.181297* 0.174781* 0.205293* 0.076473 0.187137* 0.167030* 0.197956* 0.043907 0.184528*
Lipid Particles 0.004853 0.001484 0.001443 0.001113 0.006712 0.001056 0.000888 0.000676 0.006526 0.001186 0.001174 0.000871
Mitochondria 0.615563* 0.134926* 0.015399 0.128757* 0.209294* 0.247798* 0.086164 0.115557* 0.249921* 0.213484* 0.049763 0.121454*
Mitotic Spindle 0.008135 0.056073 0.112597* 0.111071* 0.022923 0.038011 0.132357* 0.100099* 0.021444 0.043502 0.122193* 0.105001*
None 0.000561 0.000454 0.002454 0.000282 0.000366 0.000387 0.000358 0.000343 0.000386 0.000407 0.001436 0.000316
Nuclear Periphery 0.000223 0.000099 0.000927 0.000244 0.000249 0.000090 0.000392 0.000099 0.000247 0.000093 0.000667 0.000164
Nuclear Periphery Foci 0.001034 0.000874 0.001301 0.001015 0.000833 0.000226 0.001110 0.000489 0.000853 0.000423 0.001208 0.000724
Nucleolus 0.004604 0.000438 0.001047 0.000171 0.000464 0.000276 0.000756 0.000094 0.000878 0.000325 0.000906 0.000128
Nucleus 0.001480 0.001798 0.102944 0.000714 0.002690 0.001131 0.003537 0.000744 0.002569 0.001334 0.054672 0.000731
Peroxisomes 0.048552 0.036217 0.010456 0.035232 0.019190 0.031230 0.020560 0.026064 0.022126 0.032746 0.015362 0.030160
Vacuole 0.016960 0.050463 0.072706 0.060535 0.049802 0.041491 0.166870 0.059268 0.046518 0.044219 0.118431 0.059834
Vacuole Periphery 0.026215 0.025892 0.004033 0.023855 0.028562 0.019639 0.035482 0.022734 0.028327 0.021540 0.019304 0.023235

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.52 -5.80 -11.54 -9.75 -10.24 -1.34 -4.70 -9.77 -8.76 -7.28 -2.55 -4.95 -14.50 -13.11 -12.64
Bud Neck 0.99 -2.60 1.53 2.80 16.44 -1.49 -7.01 5.05 6.85 14.21 -0.49 -10.96 4.78 7.20 21.54
Bud Site -14.74 -8.76 -22.43 -7.60 -19.41 -4.45 -21.66 -25.30 -22.42 -8.41 -11.42 -18.38 -32.64 -23.44 -20.00
Cell Periphery 1.87 3.20 0.40 -5.84 -15.58 1.80 2.13 -1.06 -8.30 -10.27 1.89 3.05 -1.19 -10.61 -18.16
Cytoplasm -15.69 -88.12* -21.25 -0.22 63.95* 1.97 -18.73 -12.79 -15.01 4.75 -1.97 -56.27 -13.41 -12.57 44.64*
Cytoplasmic Foci -16.80 0.91 -5.31 17.78 -13.78 16.72 32.18 29.39 15.23 -2.21 12.26 36.65 29.40 23.21 -11.30
Eisosomes 0.99 5.75 -1.48 -5.22 -18.56 6.46 15.71 8.24 1.51 -11.74 7.30 18.07 6.43 -1.75 -21.96
Endoplasmic Reticulum 0.08 -0.51 0.22 0.39 2.36 5.34 4.46 4.97 -1.49 1.37 4.90 3.54 4.53 -0.96 3.07
Endosome -2.48 7.45 -0.20 5.25 -26.79* -3.44 6.05 10.45 14.95 5.26 -3.44 18.50 8.59 14.73 -14.72
Golgi -6.82 8.41 -6.37 0.80 -29.28* -4.86 20.49 -0.67 3.98 -20.20* -5.51 28.71 -1.69 4.12 -35.46*
Lipid Particles 2.40 2.09 2.54 0.39 3.18 7.71 7.68 8.07 0.74 1.96 7.92 7.47 8.18 0.45 4.15
Mitochondria 18.77* 24.31 19.34 1.27 -19.33* -4.60 19.21 12.87 18.81 -6.11 4.59 30.26 17.74 16.83 -18.54
Mitotic Spindle -11.48 -22.86* -19.16 -8.68 -1.51 -5.59 -24.07* -17.61 -13.89 5.16 -9.09 -29.52 -23.53 -16.85 2.42
None 0.66 -12.49 1.98 1.84 24.77* -0.16 -0.19 -0.20 0.02 -0.12 -0.22 -19.37 0.73 0.59 16.36
Nuclear Periphery 1.05 -8.47 -0.30 -1.92 9.73 3.31 -3.59 2.81 -1.50 8.40 3.43 -10.83 1.16 -2.31 12.75
Nuclear Periphery Foci 0.20 -1.19 -0.12 -0.43 1.80 3.42 -1.74 0.95 -3.06 2.64 2.11 -3.28 0.01 -2.13 3.35
Nucleolus 1.51 1.19 1.61 2.16 8.19 1.63 -3.79 5.00 2.16 8.96 1.87 -0.82 2.57 2.68 11.86
Nucleus -0.73 -40.81 0.04 1.09 41.42 3.96 -6.28 3.24 -0.71 8.44 3.40 -36.92 3.45 -0.08 37.63
Peroxisomes 1.40 4.76 1.57 0.39 -12.15 -5.93 -0.15 -3.43 2.59 -3.41 -5.46 5.82 -4.13 1.63 -11.67
Vacuole -7.57 -17.72 -10.33 -3.88 6.84 2.97 -28.69 -4.42 -7.63 24.40 0.81 -28.70 -6.77 -8.73 22.57
Vacuole Periphery 0.13 5.89 0.76 1.16 -12.46 5.75 -1.84 3.63 -1.52 5.36 4.68 7.96 3.71 -0.75 -4.40
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Localization
Cell Percentages mitochondrion (73%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Nif3

Nif3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nif3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available