Standard name
Human Ortholog
Description Glutamyl-tRNA synthetase (GluRS); forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0.06 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0.07 0.05 0.07 0.08 0.11 0.09 0.13 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.96 0.94 0.9 0.85 0.8 0.69 0.77 0.7 0.65 0.64 0.96 0.97 0.98 0.99 0.98 0.98 0.97 0.96 0.96 0.77 0.82 0.83
Endoplasmic Reticulum 0 0 0 0 0.09 0.1 0.16 0.27 0.15 0.2 0.18 0.24 0 0 0 0 0 0 0 0 0 0.15 0.12 0.11
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 5 15 11 20 32 32 38 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 1 0 0 0 0 3 3 2 3 12 4 0 0 0 0 0 0 2 1 2 1 4 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 6 17 17 13 40 33 47 41 63 53 75 1 4 2 3 2 1 0 0 1 0 0 0
Cytoplasm 334 498 510 307 379 465 512 439 404 388 367 359 346 382 326 240 136 151 327 490 553 156 285 262
Endoplasmic Reticulum 3 8 17 11 40 56 105 173 78 108 100 137 13 13 3 6 2 2 2 4 9 31 41 34
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Golgi 0 0 1 3 1 2 3 9 13 8 18 10 0 0 0 0 1 1 0 0 0 2 0 1
Mitochondria 0 0 0 1 0 0 1 0 8 11 14 4 0 0 0 0 0 0 0 0 3 1 3 1
Nucleus 0 0 0 1 1 1 0 1 1 0 2 1 1 0 2 0 0 0 0 1 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 4 3 2 4 1 12 4 8 28 10 2 2 1 2 0 4 0 7 4 4 5 8
Unique Cell Count 337 507 534 327 423 548 637 638 524 553 564 562 361 395 332 243 139 154 338 510 579 203 348 317
Labelled Cell Count 337 514 549 344 437 573 673 695 571 621 626 639 363 401 334 251 141 159 338 510 579 203 348 317


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 70.8 70.6 53.2 48.8 46.7 41.7 39.5 39.5 36.0 33.2 29.3 34.1 66.8 68.2 63.3 90.0 97.0 79.4 59.9 66.1 71.5
Std Deviation (1e-4) 17.0 15.0 12.9 14.4 11.6 10.5 9.5 9.4 9.0 7.9 7.0 8.2 16.9 17.0 17.8 26.1 29.1 28.5 16.3 19.7 21.6
Intensity Change (Log2) – – – -0.13 -0.19 -0.35 -0.43 -0.43 -0.56 -0.68 -0.86 -0.64 0.33 0.36 0.25 0.76 0.87 0.58 0.17 0.31 0.43

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 3.6 3.0 4.6 5.6 5.6 6.1 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 3.4 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.5 -0.1 3.0 1.7 3.1 3.3 5.2 4.2 6.1 -3.0 -2.2 -2.5 -1.6 0 0
Cytoplasm -1.0 -3.5 -5.9 -7.7 -11.6 -8.7 -11.0 -12.6 -12.9 0.2 0.9 2.1 2.3 1.3 1.4
Endoplasmic Reticulum 0.1 4.1 4.6 7.4 11.1 6.7 8.4 7.8 10.1 0.3 0.1 -2.2 -0.5 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 3.3 0 3.8 2.6 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 3.3 3.7 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 1.7 0 1.1 4.2 1.5 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 47.4938 68.2619 59.5845 57.5225 52.0618 62.636 62.9413 83.2471 76.7244 76.9103 72.9004 78.8943 62.0997 81.3205 74.2979 60.4248 62.5399 71.446
Actin 0.012 0.0001 0.0018 0.0002 0.0007 0.0007 0.0101 0.0015 0.0066 0.0001 0.0068 0.0011 0.0007 0.0003 0.0042 0.0058 0.0002 0.001
Bud 0.0011 0.0004 0.001 0.0011 0.001 0.0007 0.0008 0.0003 0.0008 0.0006 0.0008 0.001 0.0011 0.0005 0.0005 0.0091 0.0006 0.0003
Bud Neck 0.0019 0.0004 0.0007 0.0007 0.0006 0.002 0.0008 0.0005 0.0022 0.0005 0.0005 0.0012 0.0005 0.0005 0.0006 0.0011 0.0007 0.0016
Bud Periphery 0.0013 0.0003 0.0017 0.0005 0.0011 0.0015 0.0012 0.0002 0.0007 0.0003 0.0009 0.001 0.0011 0.0003 0.0004 0.0142 0.0025 0.0003
Bud Site 0.0021 0.0005 0.0011 0.0003 0.0001 0.0001 0.0008 0.0004 0.0008 0.0001 0.0021 0.0001 0.0006 0.0012 0.0002 0.011 0.0001 0.0002
Cell Periphery 0.0073 0.0034 0.0094 0.002 0.0033 0.0086 0.0097 0.0095 0.0093 0.0035 0.0008 0.0068 0.01 0.0064 0.0085 0.0186 0.0038 0.0042
Cytoplasm 0.6901 0.9574 0.8253 0.6504 0.8039 0.8942 0.7438 0.9364 0.8765 0.8623 0.8706 0.8699 0.8435 0.9443 0.904 0.7054 0.8403 0.8716
Cytoplasmic Foci 0.0114 0.0009 0.0066 0.0091 0.0044 0.0021 0.008 0.002 0.0056 0.0015 0.0135 0.0042 0.0088 0.0011 0.0037 0.0042 0.0061 0.0047
Eisosomes 0.0002 0 0.0002 0.0001 0.001 0 0.0002 0 0.0001 0 0.0007 0.0032 0.0001 0 0.0001 0.0003 0.0001 0.0002
Endoplasmic Reticulum 0.071 0.0097 0.0502 0.0103 0.0116 0.0246 0.0592 0.0187 0.0172 0.0045 0.0028 0.0446 0.0374 0.0122 0.0149 0.0098 0.014 0.0536
Endosome 0.0201 0.0017 0.0048 0.0132 0.0147 0.0051 0.0126 0.0012 0.0036 0.0046 0.0062 0.0144 0.0069 0.0018 0.0044 0.0121 0.0092 0.0105
Golgi 0.0033 0.0002 0.0008 0.0008 0.0011 0.0006 0.0021 0.0004 0.0008 0.0001 0.0016 0.0047 0.0012 0.0003 0.0008 0.0021 0.0004 0.0037
Lipid Particles 0.0038 0.0004 0.0046 0.006 0.0029 0.0004 0.0061 0.0011 0.0023 0.0003 0.0069 0.0007 0.0047 0.0006 0.0018 0.0095 0.0027 0.0026
Mitochondria 0.0043 0.0002 0.0065 0.0043 0.0468 0.0004 0.0063 0.0002 0.0018 0.0001 0.0078 0.0152 0.0023 0.0006 0.0014 0.0192 0.0021 0.01
None 0.0032 0.0001 0.0035 0.002 0.0051 0.0002 0.0058 0.0002 0.0012 0.0002 0.0028 0.0004 0.0023 0.0002 0.0025 0.0009 0.0095 0.0026
Nuclear Periphery 0.0231 0.0014 0.004 0.007 0.0063 0.0042 0.0217 0.0015 0.0036 0.0036 0.0021 0.003 0.0058 0.0015 0.0027 0.004 0.0041 0.0043
Nucleolus 0.0012 0 0.0008 0.0018 0.0005 0.0001 0.0058 0.0001 0.0015 0.0001 0.0013 0.0001 0.0029 0.0005 0.0007 0.0021 0.0006 0.001
Nucleus 0.0133 0.001 0.0023 0.0034 0.0022 0.0018 0.0073 0.0008 0.0021 0.0023 0.0018 0.0013 0.003 0.0021 0.0013 0.0041 0.0023 0.0031
Peroxisomes 0.0011 0 0.0011 0.0005 0.0002 0 0.0037 0.0017 0.0005 0 0.001 0.0001 0.0029 0 0.0002 0.0005 0.0002 0.0006
Punctate Nuclear 0.0017 0 0.0002 0.0001 0.0001 0 0.0059 0 0.0017 0 0.0042 0 0.0003 0.0004 0.0007 0.0002 0.0002 0.0007
Vacuole 0.1043 0.0207 0.0649 0.2392 0.0702 0.0434 0.0775 0.0224 0.0543 0.1052 0.0489 0.0229 0.0578 0.0237 0.0425 0.1411 0.0871 0.0195
Vacuole Periphery 0.022 0.0011 0.0083 0.0471 0.0225 0.0091 0.0105 0.0009 0.0069 0.01 0.0158 0.0043 0.0059 0.0015 0.0039 0.0245 0.0132 0.0038

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 481.9289 450.7558 513.7645 456.0639 469.8084 450.5537 383.5501 371.6911 424.6298 405.0387
Translational Efficiency 1.5876 1.6087 1.4635 1.9138 1.7953 1.5263 1.5275 1.8412 1.5121 1.5945

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
238 1321 1162 1287 1440 1889 130 1057 1678 3210 1292 2344

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3560.49 4574.36 7170.01 5737.70 3969.87 4334.41 6945.92 7050.38 3911.81 4433.16 7147.46 6329.64
Standard Deviation 654.53 1113.92 1464.46 1671.44 1032.54 983.36 1237.20 1659.51 998.04 1045.76 1444.79 1789.54
Intensity Change Log 2 — 0.361494 1.009899 0.688397 — 0.126744 0.807074 0.828609 — 0.242507 0.906533 0.764009

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000148 0.000185 0.000110 0.000359 0.000074 0.000077 0.000203 0.000250 0.000085 0.000122 0.000119 0.000309
Bud Neck 0.000848 0.000568 0.002656 0.003016 0.000349 0.000333 0.006844 0.001925 0.000420 0.000430 0.003078 0.002524
Bud Site 0.010298 0.003374 0.003616 0.010546 0.003127 0.003487 0.006442 0.010128 0.004145 0.003441 0.003901 0.010357
Cell Periphery 0.043052 0.013650 0.011530 0.023397 0.012792 0.007711 0.050325 0.039316 0.017084 0.010155 0.015433 0.030575
Cytoplasm 0.564111 0.712530 0.620266 0.559804 0.777963 0.860843 0.236001 0.591958 0.747631 0.799808 0.581602 0.574303
Cytoplasmic Foci 0.018711 0.010102 0.008031 0.006633 0.007158 0.008665 0.020519 0.006639 0.008797 0.009256 0.009288 0.006635
Eisosomes 0.000004 0.000002 0.000002 0.000006 0.000001 0.000001 0.000012 0.000005 0.000002 0.000002 0.000003 0.000006
Endoplasmic Reticulum 0.002093 0.001125 0.000421 0.000423 0.001120 0.000552 0.000307 0.000360 0.001258 0.000788 0.000410 0.000394
Endosome 0.001858 0.000895 0.000614 0.003532 0.000720 0.000558 0.001034 0.000819 0.000882 0.000697 0.000656 0.002308
Golgi 0.123817 0.075983 0.028705 0.012908 0.056448 0.035751 0.034366 0.019503 0.066003 0.052308 0.029275 0.015882
Lipid Particles 0.030195 0.009534 0.008216 0.015594 0.014774 0.007991 0.041482 0.033653 0.016961 0.008626 0.011563 0.023737
Mitochondria 0.000303 0.000243 0.000249 0.002450 0.000096 0.000189 0.000096 0.000317 0.000126 0.000211 0.000234 0.001488
Mitotic Spindle 0.001575 0.001810 0.001448 0.004618 0.000871 0.001104 0.003346 0.000834 0.000971 0.001395 0.001639 0.002912
None 0.001443 0.001602 0.001624 0.002458 0.002382 0.001977 0.000694 0.001447 0.002249 0.001823 0.001530 0.002002
Nuclear Periphery 0.000483 0.000562 0.001753 0.000497 0.000355 0.000233 0.002840 0.000497 0.000373 0.000369 0.001863 0.000497
Nuclear Periphery Foci 0.012555 0.012296 0.011674 0.005433 0.010578 0.006800 0.016800 0.006943 0.010858 0.009062 0.012189 0.006114
Nucleolus 0.000146 0.000062 0.000197 0.000370 0.000112 0.000043 0.000175 0.000181 0.000117 0.000051 0.000195 0.000285
Nucleus 0.004231 0.006965 0.022674 0.027094 0.007514 0.004927 0.019303 0.011808 0.007048 0.005766 0.022335 0.020201
Peroxisomes 0.000091 0.000016 0.000030 0.000436 0.000037 0.000024 0.000023 0.000071 0.000045 0.000020 0.000030 0.000272
Vacuole 0.076640 0.067331 0.209364 0.294533 0.055097 0.030142 0.510480 0.248296 0.058153 0.045446 0.239662 0.273683
Vacuole Periphery 0.107396 0.081164 0.066818 0.025894 0.048431 0.028590 0.048708 0.025049 0.056794 0.050226 0.064996 0.025513

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.42 -0.28 -3.12 -1.46 -3.26 -0.44 -5.06 -6.00 -5.86 -1.47 -1.01 -5.28 -6.81 -4.00 -4.41
Bud Neck 0.98 -6.07 -7.94 -10.63 0.11 0.10 -7.32 -8.47 -8.49 5.46 -0.45 -9.27 -13.69 -13.68 2.65
Bud Site 3.57 2.96 -0.55 -6.47 -5.43 -0.82 -2.94 -6.09 -5.84 -2.58 1.46 -0.95 -7.56 -8.72 -6.78
Cell Periphery 5.79 6.31 5.00 -1.89 -3.40 4.50 -4.31 -9.84 -12.60 0.75 5.59 1.83 -5.10 -11.14 -6.87
Cytoplasm -5.80 -0.76 0.52 12.41 2.35 -8.77 20.07 14.87 23.30 -12.19 -5.61 15.58 17.61 27.15 -1.20
Cytoplasmic Foci 3.16 3.21 4.34 3.45 2.61 -2.14 -4.47 -0.10 1.96 4.44 -0.75 -2.42 2.28 3.71 4.32
Eisosomes 2.14 0.72 -2.53 -4.25 -3.47 1.41 -6.33 -9.20 -9.70 3.52 0.36 -8.05 -9.54 -8.94 -3.12
Endoplasmic Reticulum 2.27 4.88 5.07 3.28 1.18 1.83 2.73 2.55 3.06 -0.91 1.62 3.26 3.46 4.20 1.14
Endosome 4.52 5.89 -1.38 -3.00 -3.36 2.15 -3.01 -1.01 -2.31 1.60 2.40 1.89 -2.95 -3.49 -3.37
Golgi 4.56 9.63 11.37 19.96 11.50 6.40 6.47 13.32 8.59 3.49 4.19 12.96 18.47 21.03 10.26
Lipid Particles 5.08 5.31 4.12 -2.93 -3.88 4.96 -4.52 -7.87 -11.80 1.01 6.53 3.67 -3.31 -11.34 -7.85
Mitochondria 0.62 0.16 -1.89 -2.01 -1.94 -3.60 -1.47 -2.91 -1.84 -2.53 -3.03 -4.33 -2.43 -2.21 -2.05
Mitotic Spindle -0.71 -0.29 -2.21 -1.80 -2.15 -1.10 -2.56 -0.01 0.95 2.55 -2.00 -4.11 -2.63 -1.81 -1.18
None -0.69 -0.52 -1.62 -1.38 -1.35 0.76 4.72 1.48 0.80 -2.15 1.12 2.27 0.85 -0.17 -1.28
Nuclear Periphery -1.05 -5.73 0.06 1.11 5.74 3.71 -6.51 -4.40 -8.07 6.11 -0.05 -7.38 -2.66 -2.63 6.78
Nuclear Periphery Foci 0.07 0.22 4.80 8.73 7.32 5.10 -3.08 5.40 -0.22 4.93 2.58 -1.84 8.45 6.32 7.75
Nucleolus 1.01 -0.83 -2.07 -9.86 -3.01 1.73 -1.94 -1.66 -3.80 0.01 1.85 -2.76 -4.02 -9.45 -1.55
Nucleus -1.85 -10.87 -13.31 -13.22 -2.91 2.48 -4.03 -5.54 -7.65 2.34 1.30 -11.34 -13.74 -15.29 0.58
Peroxisomes 2.55 1.99 -1.00 -1.37 -1.30 1.45 1.33 -2.69 -5.67 -5.35 2.76 1.35 -1.32 -1.53 -1.44
Vacuole 0.94 -13.78 -19.41 -26.23 -5.90 7.40 -16.11 -22.70 -26.49 8.51 3.87 -23.82 -34.11 -38.17 -2.06
Vacuole Periphery 2.41 4.23 8.39 15.76 12.87 6.04 1.09 8.06 2.61 3.27 1.91 -0.79 11.69 13.84 13.30
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glutamyl-tRNA synthetase (GluRS); forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (97%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Gus1

Gus1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gus1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available