Standard name
Human Ortholog
Description Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p; PEX31 has a paralog, PEX30, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.18 0.18 0.3 0.05 0.09 0.17 0.13 0.11 0.14
Bud 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0.24 0.41 0.28 0 0 0 0 0.06 0.08
Cytoplasm 0.67 0.75 0.74 0.69 0.8 0.66 0.58 0.65 0.45 0.59 0.35 0.44 0.86 0.92 0.95 0.42 0.35 0.32 0.19 0.28 0.14 0.23 0.3 0.21
Endoplasmic Reticulum 0.05 0.15 0.08 0.11 0.06 0.05 0 0 0 0 0 0 0.1 0.05 0 0.07 0.08 0 0.34 0.27 0.23 0.32 0.26 0.26
Endosome 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.25 0.12 0.2 0.26 0.12 0.45 0.55 0.41 0.69 0.59 0.78 0.73 0 0 0 0.11 0.05 0.08 0.26 0.16 0.33 0.18 0.16 0.16
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0.14 0 0.07 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 2 1 0 0 0 0 2 0 0 0 5 6 0 27 13 15 10 20 21 33 44 52
Bud 2 3 3 2 2 5 7 8 8 5 13 2 1 2 0 8 1 1 3 2 1 2 4 12
Bud Neck 0 1 0 0 0 0 0 1 0 0 0 1 1 0 0 0 1 0 3 6 1 4 8 11
Bud Site 0 0 0 0 0 0 1 1 0 2 2 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 7 0 8 0 6 5 1 1 2 6 6 8 9 21 36 30 14 1 4 3 10 23 31
Cytoplasm 100 156 76 87 88 130 156 221 80 134 77 137 247 557 498 63 26 16 38 67 17 58 119 80
Endoplasmic Reticulum 8 31 8 14 7 9 6 0 4 4 5 3 28 32 14 11 6 1 70 63 29 82 105 100
Endosome 7 0 0 0 1 1 2 6 0 0 0 0 1 2 3 12 1 1 7 7 1 3 4 8
Golgi 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 3 2 1 3 0 2
Mitochondria 37 25 21 33 13 89 150 140 124 134 175 229 4 12 6 16 4 4 53 38 43 44 65 61
Nucleus 0 1 2 1 4 2 1 1 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 1
Nuclear Periphery 1 1 0 0 0 1 1 2 0 1 0 2 0 0 0 0 0 0 1 1 0 0 1 1
Nucleolus 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 1 0 1 1 2 0 0 1 0 0 0 0 0 0 1 5 0 1 0 0 0 1 2 1
SpindlePole 0 0 0 0 0 0 3 10 1 1 5 7 1 0 0 5 1 2 1 1 0 0 2 3
Vac/Vac Membrane 7 4 0 0 3 3 3 7 2 3 1 5 2 4 2 13 1 7 8 16 3 5 10 13
Unique Cell Count 149 209 103 126 110 196 271 338 179 227 223 314 287 606 523 149 74 50 209 238 129 255 401 390
Labelled Cell Count 169 232 113 147 120 247 335 399 222 288 284 395 298 624 546 196 86 62 209 238 129 255 401 390


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 4.5 4.3 4.2 4.1 3.7 3.0 3.5 3.3 2.7 2.8 2.6 4.7 4.6 4.8 6.9 8.0 8.6 4.7 4.9 5.7
Std Deviation (1e-4) 0.8 1.1 1.3 1.7 1.3 1.5 1.1 1.5 1.5 0.9 0.8 1.0 1.1 1.3 1.3 1.2 1.4 1.3 1.4 1.5 2.2
Intensity Change (Log2) – – – -0.02 -0.05 -0.2 -0.5 -0.27 -0.37 -0.64 -0.59 -0.73 0.14 0.1 0.17 0.69 0.9 1.0 0.13 0.19 0.41

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 – –
Bud Neck – – – – – – – – – – – – 0 – –
Bud Site – – – – – – – – – – – – 0 – –
Cell Periphery – – – – – – – – – – – – 0 – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 – –
Endosome – – – – – – – – – – – – 0 – –
Golgi – – – – – – – – – – – – 0 – –
Mitochondria – – – – – – – – – – – – 0 – –
Nuclear Periphery – – – – – – – – – – – – 0 – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 – –
Peroxisomes – – – – – – – – – – – – 0 – –
SpindlePole – – – – – – – – – – – – 0 – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 – –
Cytoplasm – – – – – – – – – – – – 0 – –
Nucleus – – – – – – – – – – – – 0 – –
Vacuole – – – – – – – – – – – – 3.1 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.3819 0.8512 0.5942 0.4512 0.0817 0.6804 0.8619 0.7154 0.9316 0.406 0.1671 0.7774 2.4464 2.2705 1.9278 2.3503 2.1021 1.8958
Actin 0.0232 0.0014 0.0035 0.0015 0.0037 0.0034 0.0298 0.0051 0.0115 0.0016 0.0025 0.0129 0.0538 0.001 0.0138 0.0098 0.0593 0.0101
Bud 0.0084 0.0002 0.0009 0.0001 0.0002 0.0001 0.0006 0.0009 0.0016 0.001 0.0001 0.0005 0.0011 0.0028 0.0071 0.0008 0.0003 0.0002
Bud Neck 0.0014 0.0003 0.0006 0.0004 0.0008 0.0031 0.0021 0.0007 0.002 0.001 0.0019 0.0063 0.0054 0.0003 0.0067 0.0017 0.0018 0.0036
Bud Periphery 0.0016 0.0004 0.0005 0.0005 0.0009 0.0004 0.0016 0.0015 0.0023 0.0031 0.0003 0.0015 0.0039 0.0028 0.0054 0.0018 0.0005 0.0009
Bud Site 0.0081 0.0086 0.0061 0.0001 0.0008 0.0005 0.0108 0.0187 0.0071 0.0003 0.0009 0.0007 0.0059 0.0216 0.0035 0.0032 0.0009 0.0002
Cell Periphery 0.0022 0.0016 0.0013 0.0005 0.0012 0.0016 0.0035 0.002 0.002 0.0015 0.001 0.0005 0.0027 0.003 0.0022 0.0005 0.0008 0.0005
Cytoplasm 0.136 0.2757 0.2241 0.2729 0.2428 0.3264 0.1289 0.1348 0.1454 0.157 0.1945 0.2082 0.1389 0.2044 0.2217 0.1432 0.2421 0.2345
Cytoplasmic Foci 0.015 0.0089 0.0142 0.07 0.0107 0.0285 0.0407 0.0137 0.0175 0.005 0.0113 0.016 0.0273 0.0222 0.0105 0.0292 0.0156 0.0119
Eisosomes 0.0021 0.0003 0.0005 0.0004 0.0007 0.0003 0.0013 0.0007 0.0009 0.0005 0.0003 0.0003 0.0013 0.0004 0.0005 0.0004 0.0007 0.0003
Endoplasmic Reticulum 0.0324 0.0347 0.0171 0.0588 0.0336 0.0135 0.0164 0.0112 0.0233 0.0059 0.0043 0.0175 0.0217 0.0102 0.0217 0.0303 0.0084 0.0106
Endosome 0.0042 0.0039 0.0038 0.0127 0.014 0.0064 0.0231 0.0054 0.0135 0.0015 0.0018 0.0151 0.0096 0.0019 0.0049 0.0133 0.0064 0.0025
Golgi 0.002 0.0005 0.0012 0.001 0.0007 0.0007 0.0134 0.004 0.0052 0.0003 0.0014 0.0041 0.0042 0.0003 0.0017 0.0038 0.0031 0.001
Lipid Particles 0.0111 0.0021 0.0042 0.0059 0.0019 0.0018 0.0207 0.0082 0.0092 0.0011 0.0114 0.0099 0.0168 0.0026 0.0043 0.0155 0.0044 0.0074
Mitochondria 0.0008 0.0002 0.0006 0.0008 0.0004 0.0009 0.0025 0.0015 0.0132 0.0007 0.0005 0.0017 0.0022 0.0021 0.0047 0.0086 0.0009 0.0006
None 0.7449 0.6559 0.7114 0.5559 0.6789 0.6084 0.6617 0.7827 0.7209 0.815 0.7416 0.6847 0.675 0.7169 0.6762 0.6992 0.6442 0.7077
Nuclear Periphery 0.0018 0.0009 0.0013 0.0084 0.0028 0.0006 0.0048 0.0028 0.0033 0.0007 0.0003 0.0045 0.0063 0.0007 0.0021 0.0031 0.004 0.0006
Nucleolus 0.0003 0.0002 0.0008 0.0001 0.0002 0.0001 0.001 0.0004 0.0005 0.0003 0.0005 0.0002 0.0006 0.0008 0.0004 0.0015 0.0002 0.0001
Nucleus 0.0007 0.001 0.0018 0.0016 0.0021 0.0007 0.0017 0.0007 0.0013 0.0007 0.0006 0.001 0.0022 0.0011 0.0023 0.0045 0.0007 0.0005
Peroxisomes 0.0011 0.0001 0.0003 0.0009 0.0002 0.001 0.0188 0.0016 0.0119 0.0004 0.0226 0.0099 0.0106 0.0008 0.007 0.0107 0.0028 0.0053
Punctate Nuclear 0.0011 0.001 0.0036 0.0034 0.0018 0.0008 0.0133 0.002 0.0042 0.0008 0.0014 0.0029 0.0072 0.0019 0.0015 0.0164 0.0019 0.0009
Vacuole 0.0012 0.0018 0.0019 0.0032 0.0016 0.0007 0.0028 0.0013 0.0029 0.0012 0.0007 0.0013 0.0025 0.0022 0.0014 0.0019 0.0008 0.0005
Vacuole Periphery 0.0002 0.0001 0.0002 0.0009 0.0002 0.0002 0.0007 0.0003 0.0005 0.0002 0.0001 0.0004 0.0006 0.0001 0.0003 0.0005 0.0003 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.7102 7.8115 5.2695 11.3119 7.2097 7.1455 7.8982 8.723 11.5098 13.0502
Translational Efficiency 0.7544 0.9007 1.5937 0.6552 1.2249 1.2688 0.9381 0.6503 0.6965 0.7006

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1585 777 405 1692 1507 1919 300 205 3092 2696 705 1897

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 706.30 749.97 918.53 855.39 740.84 722.83 1025.70 869.75 723.13 730.65 964.13 856.94
Standard Deviation 85.13 100.52 92.13 114.74 89.04 92.50 98.35 152.67 88.76 95.67 108.63 119.50
Intensity Change Log 2 — 0.086552 0.379046 0.276301 — -0.035506 0.469375 0.231439 — 0.025357 0.425994 0.253509

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004087 0.003165 0.001884 0.007144 0.000241 0.001930 0.004457 0.007538 0.002213 0.002286 0.002979 0.007187
Bud Neck 0.012466 0.040569 0.006813 0.015506 0.004824 0.042626 0.003337 0.012202 0.008742 0.042033 0.005333 0.015149
Bud Site 0.011812 0.027778 0.017494 0.031089 0.002574 0.017874 0.008317 0.042282 0.007310 0.020728 0.013589 0.032299
Cell Periphery 0.010742 0.000978 0.001176 0.001847 0.000568 0.000683 0.001024 0.002390 0.005783 0.000768 0.001112 0.001906
Cytoplasm 0.423066 0.265546 0.312363 0.419577 0.515307 0.358712 0.335887 0.400878 0.468023 0.331861 0.322373 0.417556
Cytoplasmic Foci 0.119334 0.361469 0.082873 0.054814 0.191924 0.297317 0.086230 0.131438 0.154713 0.315806 0.084302 0.063094
Eisosomes 0.016926 0.000821 0.000564 0.001714 0.000538 0.001773 0.000437 0.002104 0.008939 0.001499 0.000510 0.001756
Endoplasmic Reticulum 0.101044 0.008378 0.044690 0.031858 0.030294 0.006553 0.055112 0.023014 0.066561 0.007079 0.049125 0.030902
Endosome 0.006983 0.044444 0.013650 0.006499 0.006601 0.025654 0.016067 0.015961 0.006797 0.031069 0.014678 0.007521
Golgi 0.059894 0.025602 0.000706 0.002665 0.006782 0.018809 0.000490 0.008044 0.034008 0.020767 0.000614 0.003246
Lipid Particles 0.100992 0.026440 0.022125 0.017046 0.035153 0.030845 0.019548 0.019354 0.068903 0.029575 0.021028 0.017296
Mitochondria 0.021269 0.016688 0.000335 0.001042 0.002637 0.023898 0.000152 0.002035 0.012188 0.021820 0.000257 0.001149
Mitotic Spindle 0.000427 0.003018 0.000512 0.018928 0.000243 0.004714 0.000429 0.010609 0.000337 0.004225 0.000477 0.018029
None 0.010396 0.003753 0.001193 0.002058 0.005404 0.001752 0.000703 0.005392 0.007963 0.002329 0.000984 0.002418
Nuclear Periphery 0.000665 0.000443 0.003221 0.001765 0.001171 0.000445 0.002508 0.002866 0.000911 0.000444 0.002918 0.001884
Nuclear Periphery Foci 0.001386 0.000996 0.022608 0.005680 0.003006 0.000532 0.029105 0.006210 0.002175 0.000666 0.025373 0.005737
Nucleolus 0.000358 0.001688 0.000599 0.000395 0.000636 0.000921 0.000300 0.001117 0.000494 0.001142 0.000472 0.000473
Nucleus 0.050323 0.063979 0.313731 0.182866 0.164036 0.080948 0.138550 0.150544 0.105745 0.076057 0.239186 0.179373
Peroxisomes 0.037576 0.032028 0.001550 0.004166 0.003287 0.022805 0.001280 0.003517 0.020864 0.025463 0.001435 0.004096
Vacuole 0.008919 0.068839 0.151654 0.192208 0.024016 0.057968 0.295849 0.148231 0.016277 0.061101 0.213013 0.187456
Vacuole Periphery 0.001334 0.003376 0.000260 0.001132 0.000759 0.003241 0.000219 0.004272 0.001054 0.003280 0.000243 0.001471

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.96 3.69 -1.02 -1.52 -3.50 -7.24 -1.61 -1.58 -1.04 -0.56 -0.14 -0.17 -3.51 -3.29 -2.34
Bud Neck -8.01 4.40 -0.63 7.85 -5.42 -18.20 2.59 -3.11 10.83 -3.80 -18.29 4.50 -4.64 15.24 -8.36
Bud Site -4.96 -0.93 -4.95 1.00 -1.86 -10.23 -4.86 -5.41 -3.46 -4.73 -8.73 -2.06 -8.97 -2.45 -4.59
Cell Periphery 10.13 10.69 10.23 -0.73 -0.71 -1.23 -2.11 -3.32 -3.07 -2.76 10.39 10.12 8.57 -2.53 -1.77
Cytoplasm 15.45 9.88 4.49 -11.11 -6.66 18.75 14.35 6.93 -0.72 -3.33 21.21 17.46 11.34 -6.57 -8.12
Cytoplasmic Foci -26.82 6.44 18.33 36.49 5.86 -15.73 16.99 6.34 15.03 -3.63 -31.12 16.56 27.69 54.02 5.06
Eisosomes 14.89 15.14 14.36 -1.45 -2.63 -5.96 1.59 -1.36 0.53 -1.64 12.65 14.69 12.76 1.30 -3.41
Endoplasmic Reticulum 19.86 9.37 16.17 -5.32 3.56 8.28 -1.31 2.24 -1.64 2.66 21.36 5.39 13.36 -7.00 4.16
Endosome -12.68 -6.22 3.09 13.30 8.04 -14.74 -6.56 -2.62 4.87 0.52 -19.26 -9.03 1.51 19.26 9.27
Golgi 11.40 29.07 28.07 10.28 -2.59 -10.04 11.48 0.46 4.21 -1.66 8.70 28.35 25.09 16.78 -3.23
Lipid Particles 19.21 21.23 26.16 5.37 3.36 1.73 7.40 5.34 4.32 0.22 16.60 20.81 24.90 9.58 3.18
Mitochondria 2.24 15.10 14.64 9.34 -4.24 -11.79 8.26 1.21 11.77 -2.81 -6.15 16.01 14.82 15.26 -5.49
Mitotic Spindle -4.06 -0.34 -6.58 -5.27 -6.55 -4.53 -1.44 -3.32 -1.82 -3.24 -5.36 -1.11 -7.08 -4.92 -7.01
None 3.48 7.42 6.68 1.30 -1.78 6.06 8.38 0.53 -3.13 -4.33 6.83 10.06 7.63 0.35 -3.53
Nuclear Periphery 2.07 -12.00 -6.62 -7.69 2.94 4.86 -6.14 -1.49 -2.37 0.23 4.96 -12.85 -5.93 -8.04 2.31
Nuclear Periphery Foci 2.08 -9.24 -8.26 -8.87 7.30 6.19 -7.61 -2.27 -4.10 5.69 7.13 -11.88 -6.71 -10.65 9.73
Nucleolus -3.65 -3.58 -1.25 3.33 1.69 -3.41 6.32 -2.06 -0.46 -3.84 -5.39 -0.06 -0.32 4.57 -0.24
Nucleus -3.42 -19.88 -29.04 -21.75 8.47 17.44 0.99 0.83 -5.56 0.02 9.11 -14.80 -17.28 -23.62 5.30
Peroxisomes 1.85 19.35 18.21 11.90 -3.55 -16.40 7.17 0.74 14.36 -2.02 -3.09 19.25 16.72 19.76 -4.35
Vacuole -15.23 -17.84 -39.59 -25.07 -7.12 -15.19 -21.09 -9.96 -8.07 6.44 -23.36 -25.43 -39.57 -30.47 0.69
Vacuole Periphery -5.82 10.97 2.34 6.41 -2.07 -6.55 6.00 -1.45 0.08 -1.80 -7.73 12.11 0.20 5.82 -2.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p; PEX31 has a paralog, PEX30, that arose from the whole genome duplication
Localization
Cell Percentages ER (50%), cytoplasm (12%), mixed (35%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pex31

Pex31


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pex31-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available