Standard name
Human Ortholog
Description Ethanolamine-phosphate cytidylyltransferase; catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases; inability of the null mutant to synthesize phosphatidylethanolamine and phosphatidylcholine from ethanolamine is functionally complemented by human PCYT2

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.98 0.97 0.92 0.85 0.78 0.8 0.79 0.72 0.67 0.72 0.99 0.98 0.97 0.94 0.93 0.93 0.97 0.96 0.95 0.97 0.93 0.95
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.06 0.13 0.1 0.16 0.17 0.35 0.17 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.09 0.12 0.14 0.09 0.08 0.16 0.05 0.13 0 0 0 0.08 0.08 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0
Bud 0 0 0 0 0 0 3 5 0 12 8 8 0 0 0 0 1 0 1 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cell Periphery 1 2 3 0 4 3 4 2 3 5 8 8 1 1 2 10 10 15 0 0 0 0 0 0
Cytoplasm 743 376 352 335 533 429 391 397 387 407 262 349 255 366 387 301 315 309 713 352 339 187 315 244
Endoplasmic Reticulum 2 1 1 1 1 1 5 4 6 0 2 3 0 1 4 7 8 6 0 2 3 0 1 2
Endosome 0 0 0 0 0 0 0 1 0 0 1 1 0 1 0 3 1 1 2 1 2 2 2 0
Golgi 0 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 2 0 0 0 1 0
Mitochondria 4 1 0 1 7 32 66 48 80 94 138 83 0 0 0 3 3 6 4 1 3 0 3 2
Nucleus 4 1 1 1 3 14 14 18 10 20 9 20 1 4 3 3 2 3 2 4 0 1 1 0
Nuclear Periphery 0 0 0 0 0 2 0 2 1 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 1 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 1
Vac/Vac Membrane 5 3 4 14 54 58 68 45 40 93 18 62 3 14 16 25 28 16 1 2 1 0 4 2
Unique Cell Count 751 381 358 345 581 503 500 496 490 567 391 485 258 372 398 320 337 332 738 369 356 194 338 257
Labelled Cell Count 759 384 363 352 604 539 551 523 527 632 449 534 261 387 412 352 371 359 738 369 356 194 338 257


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.1 11.0 8.6 8.3 8.4 7.1 6.5 6.9 5.9 6.1 5.4 5.9 9.1 9.2 8.9 11.1 12.2 11.7 10.2 10.3 11.6
Std Deviation (1e-4) 1.1 1.5 1.2 1.0 1.2 1.2 1.1 1.0 1.0 0.8 1.0 0.9 1.5 1.0 1.1 2.0 2.0 2.1 1.4 1.5 1.8
Intensity Change (Log2) -0.05 -0.03 -0.29 -0.4 -0.32 -0.54 -0.51 -0.68 -0.55 0.08 0.09 0.04 0.37 0.5 0.44 0.24 0.26 0.43

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 1.4 0 0 0 0 2.2 2.1 3.0
Cytoplasm -1.1 -4.2 -6.5 -8.5 -8.0 -8.3 -10.2 -11.1 -10.1 0.5 0.1 -1.0 -2.9 -3.3 -3.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.9 7.2 6.1 8.0 8.1 12.4 8.2 0 0 0 0 0 0
Nucleus 0 0 2.8 2.8 3.3 0 3.2 0 3.5 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.5 5.1 5.8 6.5 4.9 4.6 7.4 2.8 6.2 0 2.3 2.5 4.3 4.5 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.2798 3.6176 3.3167 3.1634 2.5646 3.1738 4.1094 5.4237 4.9905 4.5781 4.8187 5.0176 4.846 5.8037 5.038 4.1924 5.2976 5.2047
Actin 0.0292 0.0007 0.0052 0.0101 0.0551 0.0043 0.0005 0.0013 0.002 0.0059 0.0006 0.001 0.0376 0.0011 0.0082 0.0061 0.0002 0.002
Bud 0.0014 0.0004 0.0008 0.0009 0.0007 0.0006 0.0019 0.0058 0.0027 0.0212 0.0096 0.0031 0.0016 0.0101 0.0129 0.0055 0.0148 0.009
Bud Neck 0.0088 0.0005 0.0063 0.0017 0.0013 0.0023 0.0009 0.0006 0.0008 0.0014 0.001 0.0069 0.0038 0.0004 0.0054 0.0354 0.0008 0.0023
Bud Periphery 0.0017 0.0001 0.001 0.0007 0.0006 0.0005 0.0016 0.0016 0.0028 0.0044 0.0019 0.0008 0.0013 0.0016 0.0042 0.0013 0.0018 0.0029
Bud Site 0.0052 0.0047 0.0032 0.0024 0.0016 0.0003 0.0009 0.0084 0.0011 0.0026 0.0018 0.0003 0.013 0.0072 0.0114 0.0021 0.0002 0.0015
Cell Periphery 0.0008 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0 0.0003 0.0005 0.0002 0.0002 0.0001 0.0003
Cytoplasm 0.6292 0.8932 0.8421 0.817 0.6803 0.8398 0.8578 0.8955 0.8702 0.8776 0.8951 0.8507 0.7802 0.9113 0.8678 0.8076 0.913 0.8351
Cytoplasmic Foci 0.0434 0.012 0.0217 0.0185 0.0358 0.015 0.0109 0.008 0.0067 0.0089 0.0108 0.0116 0.0263 0.0108 0.0117 0.0127 0.0098 0.0135
Eisosomes 0.0003 0 0 0.0001 0.0002 0.0001 0 0 0 0 0 0 0.0003 0 0 0.0001 0 0.0001
Endoplasmic Reticulum 0.0081 0.0026 0.0044 0.0039 0.0042 0.0045 0.003 0.002 0.0024 0.0027 0.0031 0.0028 0.0054 0.0023 0.0021 0.0017 0.0012 0.002
Endosome 0.0454 0.0043 0.0086 0.012 0.029 0.0186 0.0036 0.0032 0.0032 0.0032 0.0047 0.005 0.0262 0.0046 0.0036 0.0056 0.0025 0.0125
Golgi 0.0153 0.0003 0.0016 0.0061 0.0086 0.0024 0.0002 0.0002 0.0002 0.0003 0.0002 0.0002 0.0079 0.0011 0.0014 0.0022 0.0001 0.006
Lipid Particles 0.0113 0.0001 0.0006 0.0008 0.0164 0.0023 0.0001 0.0001 0 0.0001 0.0002 0.0001 0.0089 0.0003 0.001 0.008 0 0.0011
Mitochondria 0.0103 0.0003 0.001 0.005 0.0029 0.0041 0.0004 0.0004 0.0005 0.0015 0.0013 0.0003 0.0057 0.0032 0.0015 0.0029 0.0005 0.0099
None 0.0995 0.0557 0.0621 0.0527 0.0877 0.0354 0.0689 0.039 0.0572 0.0128 0.0242 0.0474 0.0213 0.017 0.0202 0.0107 0.0109 0.0244
Nuclear Periphery 0.0224 0.0027 0.0042 0.0123 0.006 0.0145 0.0035 0.0023 0.0032 0.0028 0.0039 0.0034 0.0072 0.0025 0.0038 0.0042 0.0022 0.0039
Nucleolus 0.0011 0.0001 0.0018 0.0007 0.0003 0.0023 0.0002 0.0002 0.0002 0.0011 0.0006 0.0003 0.0004 0.0009 0.0004 0.0023 0.0005 0.0096
Nucleus 0.0299 0.0165 0.0248 0.0291 0.0224 0.0375 0.0386 0.0251 0.0407 0.0455 0.0341 0.0513 0.0314 0.0185 0.0318 0.0612 0.0347 0.0498
Peroxisomes 0.0154 0.0004 0.0024 0.0093 0.0333 0.0011 0.0014 0.0003 0.0005 0.0014 0.0002 0.0003 0.0117 0.0012 0.0056 0.0181 0.0002 0.0013
Punctate Nuclear 0.014 0.0031 0.0058 0.0147 0.0119 0.0095 0.0042 0.0047 0.0044 0.0047 0.0044 0.0133 0.0067 0.0034 0.0052 0.0103 0.0054 0.0101
Vacuole 0.0052 0.0019 0.0018 0.0015 0.0012 0.0029 0.0011 0.001 0.0009 0.0013 0.002 0.001 0.0019 0.0016 0.0011 0.0013 0.0009 0.0021
Vacuole Periphery 0.002 0.0002 0.0004 0.0005 0.0005 0.002 0.0002 0.0001 0.0002 0.0004 0.0003 0.0002 0.0007 0.0003 0.0003 0.0004 0.0002 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 45.4076 48.7099 48.1932 42.3755 31.6442 29.4986 53.6113 47.0911 50.2469 48.3422
Translational Efficiency 0.7748 0.8936 0.6094 0.7655 0.984 1.0391 0.7886 0.6652 0.6 0.7251

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
182 1271 1960 1465 1987 1594 311 793 2169 2865 2271 2258

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1009.92 998.90 1107.75 974.57 934.26 991.30 1138.86 973.16 940.61 994.67 1112.01 974.07
Standard Deviation 145.84 200.86 157.90 143.95 120.35 129.80 158.56 132.22 124.47 165.19 158.35 139.94
Intensity Change Log 2 -0.015829 0.133391 -0.051403 0.085498 0.285694 0.058853 0.033752 0.208588 0.002632

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000316 0.000236 0.000240 0.000396 0.000075 0.000272 0.000388 0.006691 0.000095 0.000256 0.000260 0.002606
Bud Neck 0.001497 0.002030 0.002167 0.006252 0.001085 0.002058 0.002197 0.003347 0.001120 0.002046 0.002171 0.005232
Bud Site 0.005783 0.008512 0.006483 0.022201 0.001749 0.007024 0.004354 0.042221 0.002088 0.007684 0.006191 0.029232
Cell Periphery 0.000268 0.000093 0.000072 0.000177 0.000059 0.000060 0.000167 0.000274 0.000076 0.000075 0.000085 0.000211
Cytoplasm 0.626649 0.795457 0.575432 0.609031 0.755089 0.789212 0.525983 0.548414 0.744312 0.791983 0.568660 0.587743
Cytoplasmic Foci 0.140728 0.027653 0.004575 0.008834 0.048258 0.054240 0.017669 0.019389 0.056017 0.042445 0.006368 0.012541
Eisosomes 0.000064 0.000009 0.000009 0.000022 0.000014 0.000015 0.000039 0.000041 0.000018 0.000012 0.000013 0.000028
Endoplasmic Reticulum 0.004135 0.000633 0.001013 0.002154 0.000966 0.000869 0.003169 0.003489 0.001232 0.000765 0.001308 0.002623
Endosome 0.011062 0.002410 0.000844 0.002796 0.002063 0.003789 0.004051 0.008311 0.002818 0.003177 0.001283 0.004733
Golgi 0.000788 0.002576 0.000255 0.000705 0.000277 0.002101 0.000137 0.013928 0.000320 0.002312 0.000239 0.005349
Lipid Particles 0.007087 0.000857 0.000453 0.000770 0.000699 0.000726 0.001449 0.000928 0.001235 0.000784 0.000589 0.000826
Mitochondria 0.000086 0.000910 0.001017 0.001413 0.001432 0.001109 0.000226 0.005721 0.001319 0.001021 0.000909 0.002926
Mitotic Spindle 0.000325 0.010900 0.007917 0.026421 0.001938 0.007807 0.005846 0.028635 0.001802 0.009179 0.007634 0.027199
None 0.000957 0.011511 0.008585 0.006159 0.003974 0.004504 0.007779 0.010379 0.003721 0.007612 0.008475 0.007641
Nuclear Periphery 0.000425 0.000165 0.000917 0.001447 0.000258 0.000244 0.001024 0.000832 0.000272 0.000209 0.000932 0.001231
Nuclear Periphery Foci 0.008347 0.002419 0.001590 0.003107 0.001622 0.002013 0.006150 0.002487 0.002186 0.002193 0.002214 0.002890
Nucleolus 0.002864 0.000379 0.000125 0.000353 0.000215 0.000374 0.000417 0.000207 0.000437 0.000376 0.000165 0.000302
Nucleus 0.062796 0.100915 0.352493 0.184500 0.137293 0.071992 0.269352 0.146411 0.131042 0.084823 0.341107 0.171123
Peroxisomes 0.002156 0.001597 0.000119 0.000166 0.000184 0.000864 0.000188 0.000633 0.000349 0.001189 0.000128 0.000330
Vacuole 0.123204 0.030149 0.035603 0.120251 0.042376 0.050205 0.149204 0.156145 0.049158 0.041308 0.051160 0.132857
Vacuole Periphery 0.000462 0.000590 0.000092 0.002843 0.000375 0.000520 0.000212 0.001514 0.000382 0.000551 0.000109 0.002377

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.40 0.35 -0.28 -2.65 -0.97 -3.14 -8.88 -1.68 -1.42 -1.11 -4.37 -8.80 -2.26 -1.63 -1.34
Bud Neck -0.87 -4.52 -5.98 -3.53 -2.58 -4.22 -6.15 -10.56 -4.95 -0.68 -3.55 -8.55 -10.48 -5.43 -2.67
Bud Site -1.13 0.94 -3.23 -1.46 -3.77 -4.94 -7.42 -5.61 -3.08 -4.03 -6.02 -4.44 -8.63 -3.31 -5.24
Cell Periphery 3.56 3.71 3.24 -1.34 -2.63 -0.10 -8.53 -4.09 -3.99 1.75 0.35 -3.40 -4.33 -4.39 -2.09
Cytoplasm -7.77 6.56 6.93 32.96 1.23 -3.77 24.31 33.82 34.79 -0.57 -6.10 40.63 41.19 47.75 2.99
Cytoplasmic Foci 9.62 11.98 11.60 11.32 -5.74 -2.21 14.74 17.37 17.01 -0.84 4.83 24.68 22.07 20.89 -7.21
Eisosomes 7.64 7.14 5.00 -15.11 -13.32 -1.06 -9.51 -14.71 -13.64 0.15 4.58 0.34 -11.58 -19.13 -14.22
Endoplasmic Reticulum 3.45 2.61 2.20 -7.48 -2.34 0.64 -7.72 -5.11 -4.89 2.25 2.95 -3.88 -4.75 -7.77 -2.06
Endosome 5.05 6.13 5.76 1.67 -3.67 -3.15 -1.85 -0.98 1.81 0.45 -0.51 8.00 3.87 3.22 -3.76
Golgi -1.63 2.36 2.15 2.65 -0.64 -3.19 3.59 -1.89 -0.27 -2.00 -3.93 2.43 -1.65 1.94 -2.07
Lipid Particles 1.69 1.72 1.61 -0.73 -7.60 -0.15 -6.80 -7.86 -6.05 2.05 1.22 1.05 -0.08 -2.34 -6.99
Mitochondria -2.78 -7.22 -7.47 -0.03 0.47 0.46 1.57 0.02 -0.40 -1.37 0.55 0.82 0.45 -0.20 -0.71
Mitotic Spindle -4.51 -6.92 -7.55 -2.20 -2.83 -2.64 -2.27 -5.72 -3.87 -3.00 -4.22 -5.40 -8.41 -4.42 -4.09
None -7.53 -18.96 -15.59 3.19 4.45 -0.52 -3.17 -3.92 -3.44 -0.07 -4.33 -8.38 -5.64 0.08 2.60
Nuclear Periphery 2.18 -11.43 -9.55 -13.69 -2.13 0.38 -13.53 -18.23 -17.16 -0.38 1.62 -30.64 -19.10 -19.24 -2.94
Nuclear Periphery Foci 4.99 5.74 5.41 1.49 -0.72 -0.67 -5.83 -2.26 -0.64 4.79 0.02 -0.08 0.52 0.42 0.64
Nucleolus 1.10 1.18 1.12 0.51 -5.37 -1.82 -2.35 -3.08 0.39 -0.27 0.23 1.19 0.50 0.71 -5.25
Nucleus -6.31 -41.48 -21.35 -20.91 22.77 17.49 -13.62 -10.26 -19.40 7.24 12.42 -45.94 -19.47 -30.71 25.39
Peroxisomes 0.47 1.50 1.47 2.39 -1.52 -4.13 1.45 -0.87 3.81 -1.72 -2.74 2.09 1.55 3.69 -2.61
Vacuole 7.13 4.69 -6.73 -25.85 -21.25 -4.59 -12.85 -24.93 -23.08 -4.43 -0.21 -10.75 -33.72 -34.01 -24.26
Vacuole Periphery -0.20 4.54 -0.87 -0.61 -2.50 -0.91 3.10 0.26 0.87 -1.13 -1.05 4.53 -1.09 -0.35 -2.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ethanolamine-phosphate cytidylyltransferase; catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases; inability of the null mutant to synthesize phosphatidylethanolamine and phosphatidylcholine from ethanolamine is functionally complemented by human PCYT2
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ect1

Ect1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ect1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available