Standard name
Human Ortholog
Description Putative cysteine synthase; localized to the mitochondrial outer membrane
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0.14 0.11 0.1 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0.11 0.1 0.15 0.16 0.07 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0.06 0.07 0 0 0 0 0 0 0 0.12 0.18 0.19 0 0.06 0 0.06 0.07 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.16 0.11 0.37 0.33 0.36 0 0.07 0 0.08 0.06 0.08
Mitochondria 0.96 0.87 0.89 0.9 0.83 0.88 0.86 0.88 0.86 0.93 0.93 0.95 0.58 0.41 0.45 0 0.08 0.07 0.78 0.7 0.73 0.71 0.67 0.69
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.06 0 0.05 0 0 0 0.06 0.05 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleolus 0.06 0 0 0 0 0 0.05 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.09 0.07 0.05 0 0 0 0 0 0 0 0.12 0.1 0.19 0 0 0.07 0 0 0.13 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.14 0 0 0.1 0.08 0.06 0 0.08 0.05 0 0 0.26 0.31 0.21 0.29 0.24 0.24 0 0.06 0 0.06 0.08 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 1 0 0 0 1 0 0 0 0 1 0 0 1 2 6 3 1 3 4 5 10 13
Bud 5 2 5 5 3 9 24 26 17 22 15 13 1 1 5 1 6 4 1 2 1 3 8 9
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 4 2
Bud Site 0 1 2 1 1 1 7 19 4 11 6 2 0 0 0 0 2 1 – – – – – –
Cell Periphery 5 4 13 4 5 3 8 3 0 2 4 2 18 29 17 10 20 10 0 0 1 0 0 0
Cytoplasm 1 3 5 10 20 13 16 15 8 16 13 17 37 52 81 12 12 8 0 0 0 3 7 6
Endoplasmic Reticulum 4 4 0 0 3 1 7 5 0 2 0 2 0 0 1 1 10 4 0 1 0 2 4 3
Endosome 3 5 6 13 22 11 8 9 15 0 0 0 40 93 101 0 10 4 13 12 10 12 18 27
Golgi 1 8 4 1 0 0 0 0 0 0 0 0 24 81 60 27 60 35 6 13 8 23 27 44
Mitochondria 217 157 238 189 272 355 529 649 314 530 350 425 195 212 240 3 15 7 179 134 204 209 301 385
Nucleus 0 3 4 2 6 6 17 18 11 7 5 6 3 2 1 2 8 0 0 0 0 1 0 1
Nuclear Periphery 13 6 13 2 12 16 36 34 9 23 13 20 4 4 2 4 3 2 4 1 3 2 2 3
Nucleolus 13 8 7 3 7 14 31 39 15 30 15 16 2 2 3 3 4 2 2 0 0 2 2 2
Peroxisomes 2 2 24 15 15 7 16 14 8 2 6 2 41 52 99 2 7 7 6 5 35 7 15 19
SpindlePole 0 3 11 5 6 15 22 29 19 14 16 11 12 13 16 0 6 3 3 1 5 0 5 4
Vac/Vac Membrane 23 26 12 6 33 32 35 33 28 27 16 18 88 161 109 21 44 24 6 11 0 17 33 27
Unique Cell Count 225 180 268 210 328 405 618 738 367 567 375 449 338 514 528 73 181 98 230 192 280 294 449 556
Labelled Cell Count 287 234 345 256 405 483 757 893 449 686 459 535 465 703 736 88 213 114 230 192 280 294 449 556


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 6.9 6.4 6.1 6.1 5.4 5.1 4.9 5.2 4.5 4.1 4.3 7.9 7.6 7.4 10.5 9.8 10.5 8.0 7.6 7.9
Std Deviation (1e-4) 1.1 1.6 1.8 1.8 2.2 1.8 1.8 1.7 2.0 1.6 1.6 1.6 1.7 1.5 1.6 2.2 1.9 2.2 1.7 1.8 1.9
Intensity Change (Log2) – – – -0.08 -0.09 -0.25 -0.33 -0.38 -0.31 -0.52 -0.64 -0.6 0.29 0.23 0.2 0.7 0.61 0.7 0.32 0.24 0.29


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.3 1.6 1.3 1.9 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 1.8 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.7 -2.4 -3.4 -3.2 0 -4.3 0 0 0 0.3 0.5 -1.1 0 2.5 1.9
Cytoplasm 1.8 2.6 1.1 0.7 0.2 0.3 0.8 1.2 1.4 4.4 4.2 5.8 0 2.6 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 2.2 2.6 0.4 0 0 1.3 0 0 0 4.4 6.3 6.6 0 1.8 0
Golgi 0 0 0 0 0 0 0 0 0 3.3 6.1 4.8 9.4 9.4 9.4
Mitochondria 0.4 -2.0 -0.5 -1.3 -0.4 -1.2 0 0 0 -8.4 -12.8 -11.8 -14.1 -16.9 -14.7
Nucleus 0 0 0 1.1 0.9 1.2 0 0 0 0 0 0 0 0 0
Nuclear Periphery -2.4 -0.7 -0.6 0.6 -0.2 -1.6 0 0 0 -2.7 -3.7 -4.4 0 -1.8 0
Nucleolus 0 -0.4 0.6 1.6 1.8 1.0 0 0 0 0 0 0 0 0 0
Peroxisomes -0.7 -2.2 -4.4 -4.2 -5.2 -3.9 0 0 0 1.3 0.5 3.6 -1.8 -2.1 -0.6
SpindlePole -1.0 -1.7 -0.3 -0.4 -0.1 0.6 0 0 0 -0.4 -1.2 -0.8 0 -0.4 0
Vacuole -0.9 2.6 1.8 0.7 0 1.6 0.2 -0.1 -0.3 7.1 8.6 6.0 6.2 6.2 5.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.6169 -0.0197 -0.6216 -0.5821 -0.9239 -0.2854 1.4213 1.6162 1.67 1.1531 1.6487 1.6672 1.074 1.1432 1.0677 1.7693 1.5477 1.0601
Actin 0.0471 0.0064 0.0111 0.0043 0.003 0.0045 0.0243 0.014 0.0119 0.0715 0.0605 0.0044 0.011 0.0192 0.0152 0.067 0.0144 0.0062
Bud 0.0009 0.0034 0.0018 0.0035 0.0008 0.0008 0.0011 0.004 0.0019 0.0024 0.0047 0.0013 0.0029 0.007 0.0089 0.0037 0.0029 0.0011
Bud Neck 0.001 0.0004 0.012 0.0012 0.0028 0.0047 0.0023 0.0009 0.003 0.0039 0.0029 0.0048 0.0007 0.0011 0.0012 0.0036 0.0021 0.0056
Bud Periphery 0.0023 0.0125 0.0072 0.0093 0.0037 0.0016 0.0041 0.009 0.005 0.0072 0.0209 0.0041 0.0088 0.0136 0.0139 0.0069 0.0058 0.0044
Bud Site 0.004 0.0132 0.0126 0.0076 0.0013 0.0008 0.0049 0.0223 0.0091 0.0076 0.005 0.0014 0.0046 0.0318 0.0152 0.0088 0.0021 0.0012
Cell Periphery 0.001 0.0005 0.0011 0.0014 0.0006 0.0004 0.0018 0.0027 0.0016 0.0023 0.0014 0.001 0.001 0.0013 0.0014 0.0005 0.0003 0.0005
Cytoplasm 0.0105 0.0063 0.0071 0.0199 0.0041 0.0077 0.0312 0.0274 0.0383 0.0182 0.0094 0.028 0.0253 0.0222 0.0225 0.0124 0.0308 0.0145
Cytoplasmic Foci 0.0538 0.0533 0.0421 0.0624 0.0452 0.0521 0.074 0.0726 0.0467 0.0301 0.0448 0.0512 0.054 0.0692 0.0531 0.078 0.044 0.0562
Eisosomes 0.0021 0.0002 0.0014 0.0009 0.0003 0.0003 0.0007 0.0008 0.0007 0.0012 0.0015 0.0003 0.0004 0.001 0.0003 0.0003 0.0002 0.0003
Endoplasmic Reticulum 0.0039 0.0003 0.0033 0.0017 0.0002 0.002 0.0047 0.0056 0.0035 0.0041 0.0035 0.0022 0.0023 0.0021 0.0023 0.0009 0.0033 0.0016
Endosome 0.055 0.0392 0.0404 0.0486 0.0234 0.0625 0.1314 0.121 0.0905 0.0924 0.1078 0.0726 0.1026 0.1061 0.077 0.1059 0.106 0.0762
Golgi 0.0263 0.0169 0.0167 0.0346 0.0492 0.0232 0.0498 0.0525 0.0434 0.0352 0.0261 0.0447 0.0403 0.0599 0.0383 0.064 0.0616 0.0555
Lipid Particles 0.0599 0.0413 0.0653 0.0066 0.0414 0.0371 0.0484 0.02 0.0181 0.0109 0.0076 0.0199 0.0162 0.0087 0.0135 0.0129 0.0106 0.0127
Mitochondria 0.5286 0.6908 0.5942 0.5981 0.6767 0.6599 0.4652 0.5134 0.6395 0.6529 0.6228 0.6736 0.6212 0.5313 0.6369 0.5843 0.6384 0.6761
None 0.1117 0.0662 0.0991 0.0615 0.0333 0.0556 0.0814 0.0626 0.0457 0.0068 0.0263 0.0272 0.0502 0.0725 0.0309 0.0177 0.0161 0.0276
Nuclear Periphery 0.0035 0.0002 0.0011 0.0003 0.0001 0.0044 0.0045 0.003 0.0014 0.0005 0.0075 0.0084 0.0067 0.0013 0.0033 0.0004 0.015 0.0007
Nucleolus 0.0059 0.0033 0.0042 0.0011 0.0011 0.0038 0.0034 0.0017 0.0042 0.0009 0.0029 0.0007 0.0008 0.0012 0.0009 0.0005 0.0009 0.0005
Nucleus 0.0049 0.0005 0.002 0.0007 0.0004 0.0025 0.0026 0.0029 0.0026 0.0009 0.0051 0.0012 0.0023 0.0014 0.0017 0.0006 0.0084 0.0006
Peroxisomes 0.0543 0.0364 0.0615 0.1169 0.1062 0.0599 0.0283 0.0278 0.0145 0.0333 0.0173 0.037 0.0267 0.0313 0.0403 0.0208 0.0174 0.0484
Punctate Nuclear 0.0092 0.0013 0.0082 0.0003 0.0004 0.0034 0.0052 0.0016 0.0019 0.0005 0.0044 0.0013 0.0026 0.0007 0.0033 0.0008 0.0086 0.0006
Vacuole 0.0098 0.0042 0.0055 0.0146 0.0033 0.0079 0.021 0.0233 0.011 0.0121 0.0128 0.0091 0.0111 0.012 0.0143 0.0057 0.0065 0.0058
Vacuole Periphery 0.0043 0.0032 0.0024 0.0045 0.0026 0.0049 0.0095 0.0109 0.0054 0.0051 0.0049 0.0056 0.0083 0.0051 0.0058 0.0042 0.0046 0.004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.8709 26.7039 19.1962 18.2831 19.3653 27.0567 21.094 17.3692 19.9167 25.5097
Translational Efficiency 0.9764 0.658 0.7349 0.797 1.0897 0.688 0.8101 1.0163 0.8589 0.9553

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1647 647 1923 809 2003 1530 1061 912 3650 2177 2984 1721

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 730.07 874.23 1003.25 928.76 752.67 836.20 1039.11 1000.94 742.47 847.50 1016.00 967.01
Standard Deviation 106.04 402.99 161.72 180.37 120.26 154.86 166.48 194.23 114.62 255.78 164.33 191.26
Intensity Change Log 2 — 0.259978 0.458574 0.347271 — 0.151831 0.465259 0.411266 — 0.206093 0.461972 0.380111

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000587 0.000778 0.003815 0.007364 0.000865 0.002270 0.003321 0.009600 0.000739 0.001827 0.003639 0.008549
Bud Neck 0.006762 0.012410 0.002807 0.007654 0.003564 0.009273 0.006846 0.006774 0.005007 0.010205 0.004243 0.007187
Bud Site 0.012849 0.028686 0.025068 0.087468 0.022263 0.030430 0.041894 0.102326* 0.018015 0.029912 0.031051 0.095342
Cell Periphery 0.000796 0.000668 0.000515 0.002000 0.000698 0.000787 0.000414 0.002648 0.000742 0.000752 0.000479 0.002343
Cytoplasm 0.019380 0.018865 0.006368 0.027151 0.014022 0.023584 0.013287 0.039723 0.016439 0.022181 0.008828 0.033813
Cytoplasmic Foci 0.044347 0.056858 0.029780 0.031203 0.035225 0.049724 0.047370 0.040980 0.039341 0.051844 0.036034 0.036384
Eisosomes 0.000086 0.000104 0.000061 0.000134 0.000061 0.000094 0.000078 0.000120 0.000072 0.000097 0.000067 0.000126
Endoplasmic Reticulum 0.001227 0.000797 0.001515 0.001576 0.000798 0.000862 0.001140 0.001356 0.000992 0.000843 0.001381 0.001459
Endosome 0.067812 0.099820 0.042464 0.043799 0.051807 0.064430 0.053107 0.043301 0.059029 0.074948 0.046248 0.043535
Golgi 0.059569 0.066274 0.068742 0.061051 0.077802 0.067239 0.068960 0.088815 0.069575 0.066952 0.068820 0.075764
Lipid Particles 0.008091 0.007424 0.000986 0.001027 0.002257 0.003483 0.001687 0.000982 0.004889 0.004654 0.001235 0.001003
Mitochondria 0.690712* 0.579512* 0.696220* 0.555649* 0.727634* 0.634604* 0.574566* 0.488749* 0.710974* 0.618230* 0.652965* 0.520197*
Mitotic Spindle 0.006907 0.020485 0.041462 0.046173 0.009956 0.019163 0.065778 0.054499 0.008580 0.019556 0.050108 0.050585
None 0.002387 0.002977 0.000491 0.000671 0.000996 0.002047 0.000568 0.000595 0.001623 0.002323 0.000518 0.000630
Nuclear Periphery 0.000467 0.000376 0.000651 0.000519 0.000090 0.000233 0.000932 0.000177 0.000260 0.000276 0.000751 0.000338
Nuclear Periphery Foci 0.000425 0.000914 0.000646 0.000760 0.000241 0.000485 0.000665 0.000315 0.000324 0.000613 0.000652 0.000524
Nucleolus 0.001176 0.002773 0.000407 0.000348 0.000323 0.000801 0.000514 0.000275 0.000708 0.001387 0.000445 0.000309
Nucleus 0.002804 0.005823 0.001837 0.003995 0.000727 0.006753 0.002704 0.002074 0.001664 0.006476 0.002146 0.002977
Peroxisomes 0.020135 0.030537 0.010896 0.027623 0.015585 0.030636 0.031703 0.026901 0.017638 0.030606 0.018295 0.027240
Vacuole 0.025489 0.038357 0.030729 0.052168 0.015073 0.028762 0.045081 0.052895 0.019773 0.031614 0.035832 0.052553
Vacuole Periphery 0.027993 0.025563 0.034539 0.041668 0.020013 0.024340 0.039385 0.036895 0.023614 0.024703 0.036262 0.039139

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.16 -4.71 -4.99 -4.85 -2.30 -4.35 -5.36 -5.47 -4.51 -3.75 -4.71 -6.18 -7.37 -6.22 -4.19
Bud Neck -2.86 4.89 -0.91 2.12 -4.65 -4.84 -4.07 -4.40 1.47 -0.15 -5.04 1.15 -3.46 2.28 -4.47
Bud Site -4.25 -5.50 -11.74 -8.16 -9.47 -2.78 -5.79 -12.38 -10.72 -8.54 -5.24 -6.76 -16.97 -13.43 -13.47
Cell Periphery 0.70 1.53 -1.98 -2.23 -2.49 -1.07 3.30 -3.07 -2.88 -3.55 -0.28 2.47 -3.63 -3.58 -4.25
Cytoplasm 0.06 5.43 -2.99 -2.77 -6.63 -3.51 -0.53 -6.98 -4.29 -6.54 -2.75 4.20 -7.32 -4.74 -9.83
Cytoplasmic Foci -2.51 5.01 3.53 5.11 -0.82 -4.88 -3.68 -1.90 2.31 1.52 -4.82 1.64 1.01 5.23 -0.41
Eisosomes -2.00 4.61 -2.21 -1.27 -3.40 -6.41 -3.80 -6.94 -2.78 -4.44 -5.32 1.30 -4.94 -2.54 -5.33
Endoplasmic Reticulum 1.47 -0.75 -1.20 -3.15 -0.31 -0.39 -2.30 -3.00 -2.86 -1.12 0.84 -1.66 -2.66 -4.05 -0.44
Endosome -4.96 7.16 5.85 8.76 -0.25 -3.52 -0.32 2.80 5.80 2.94 -4.98 5.41 6.10 9.85 1.37
Golgi -1.13 -2.07 0.00 1.00 1.69 2.40 1.93 -1.25 -3.04 -2.68 0.81 0.37 -0.90 -1.51 -1.18
Lipid Particles 0.41 7.22 6.92 4.41 -0.40 -1.96 0.96 2.72 3.86 1.36 0.24 7.17 7.38 5.87 0.62
Mitochondria 6.55 -0.33 9.24 1.79 9.64 8.12 11.65 17.17 10.07 5.43 9.85 7.25 18.82 9.05 12.46
Mitotic Spindle -4.58 -12.68 -9.11 -5.01 -0.85 -5.03 -12.11 -9.26 -7.12 1.50 -7.16 -17.20 -12.87 -8.89 -0.21
None -0.47 2.99 2.69 2.02 -3.30 -2.39 2.59 3.51 3.34 -0.09 -1.39 3.73 3.39 3.74 -1.96
Nuclear Periphery 0.50 -1.12 -0.27 -0.77 0.69 -3.25 -2.77 -3.81 0.54 2.37 -0.24 -3.55 -0.95 -0.87 2.71
Nuclear Periphery Foci -1.86 -2.11 -1.50 0.45 -0.50 -1.94 -3.53 -1.92 0.84 2.27 -2.43 -4.30 -2.08 0.38 0.78
Nucleolus -1.77 2.56 2.81 2.76 0.34 -2.48 -1.69 0.37 2.64 1.93 -2.18 1.62 2.73 3.62 1.36
Nucleus -1.92 0.93 -1.83 0.36 -2.30 -5.59 -3.50 -4.24 2.09 0.31 -5.32 -2.07 -3.88 1.71 -1.94
Peroxisomes -2.88 4.36 -1.93 0.59 -4.60 -5.51 -4.84 -3.59 0.97 1.11 -5.90 -0.35 -3.89 1.10 -3.52
Vacuole -3.66 -2.66 -7.55 -4.07 -6.15 -7.18 -10.18 -10.43 -7.27 -2.97 -6.83 -9.90 -12.90 -8.76 -7.08
Vacuole Periphery 0.88 -2.69 -3.47 -3.78 -1.65 -2.24 -6.11 -4.93 -3.39 0.81 -0.65 -6.84 -6.00 -5.23 -0.71
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative cysteine synthase; localized to the mitochondrial outer membrane
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mcy1

Mcy1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mcy1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available