Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 1.0 0.99 1.0 0.98 0.95 0.8 0.69 0.76 0.74 0.75 0.74 0.97 0.96 0.97 1.0 1.0 1.0 0.95 0.97 0.95 0.91 0.89 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0.18 0.29 0.21 0.21 0.18 0.19 0 0 0 0.05 0 0 0 0 0 0 0.05 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 3 4 6 12 16 21 32 0 0 0 0 0 0 1 0 0 0 0 0
Bud 1 0 0 0 0 1 1 2 4 1 1 6 0 3 0 0 0 0 0 0 0 1 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 2 1 0 5 6 16 11 11 38 22 30 0 2 3 0 2 0 0 0 0 0 1 0
Cytoplasm 125 233 216 404 616 527 538 508 430 543 383 519 303 437 525 141 164 109 116 215 199 245 362 431
Endoplasmic Reticulum 0 0 1 2 7 19 123 214 117 151 90 132 9 15 16 7 4 4 1 1 5 5 22 16
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 1 0 0 0 0 0 4 3 8 15 5 17 2 0 1 0 0 0 0 0 0 0 1 0
Mitochondria 0 0 1 0 0 5 5 4 7 7 13 28 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 4 0 0 1 1 0 0 1 0 0 1 0 0 0 1 0 1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 3 5 1 1 1 1 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 1 0 1 0 2 3 2 2 3 1 1 2 2 0 0 0 0 1 0 7 7 5
Unique Cell Count 126 233 218 406 627 553 676 738 564 735 512 703 313 454 542 141 164 109 122 223 211 270 409 469
Labelled Cell Count 128 235 221 406 629 561 696 760 592 775 540 767 315 460 548 148 170 114 122 223 211 270 409 469


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 153.0 189.9 124.2 127.7 93.3 60.8 54.7 53.3 49.6 49.2 44.4 43.6 152.5 151.0 150.4 196.7 211.0 203.9 174.4 182.4 186.2
Std Deviation (1e-4) 40.0 33.8 29.8 29.1 20.6 13.6 12.7 13.1 11.2 11.7 11.2 10.5 35.6 34.4 34.3 53.4 58.7 49.2 45.4 49.0 43.7
Intensity Change (Log2) – – – 0.04 -0.41 -1.03 -1.18 -1.22 -1.32 -1.34 -1.49 -1.51 0.3 0.28 0.28 0.66 0.76 0.71 0.49 0.55 0.58

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000100200WT3HU80HU120HU1600100200WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30100200WT1AF100AF140AF1800100200
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 2.6 2.8 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 3.1 2.7 2.7 0 0 0 0 0 0
Cytoplasm 0.6 -0.9 -2.5 -6.9 -9.2 -7.6 -8.1 -7.8 -8.1 -1.7 -2.1 -1.8 1.1 1.2 1.0
Endoplasmic Reticulum 0 0 2.3 6.6 8.9 7.1 7.1 6.4 6.7 0 2.3 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 2.6 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 142.2067 186.3671 175.9856 164.3058 182.4247 173.8979 130.9823 175.8183 167.0233 148.358 122.002 145.2794 127.4352 195.2384 173.3512 159.9342 174.8711 176.1078
Actin 0.0013 0.0003 0.0004 0.0002 0.0005 0.0028 0.0119 0.0003 0.0005 0.0032 0.018 0.0034 0.033 0.0003 0.0097 0.0045 0.0002 0.002
Bud 0.0015 0.0007 0.0011 0.0012 0.0008 0.0017 0.0032 0.0008 0.0011 0.0032 0.0053 0.0056 0.0016 0.0007 0.0018 0.004 0.0008 0.0083
Bud Neck 0.0009 0.0006 0.001 0.0005 0.0016 0.0035 0.0008 0.0004 0.0011 0.001 0.0017 0.0018 0.0169 0.0004 0.0043 0.0008 0.0004 0.0011
Bud Periphery 0.0023 0.0007 0.001 0.0011 0.0003 0.0029 0.0035 0.0006 0.0007 0.0027 0.0058 0.0031 0.002 0.0003 0.0008 0.0029 0.0004 0.0024
Bud Site 0.0007 0.0005 0.0005 0.0004 0.0002 0.0002 0.0033 0.0005 0.0005 0.0009 0.002 0.001 0.0142 0.0009 0.0133 0.0032 0.0001 0.0005
Cell Periphery 0.0601 0.0441 0.0506 0.0384 0.0066 0.0156 0.0351 0.0082 0.0266 0.0078 0.0071 0.0109 0.051 0.0182 0.0192 0.0172 0.0087 0.0009
Cytoplasm 0.5544 0.8151 0.7064 0.4839 0.78 0.733 0.6531 0.9213 0.7899 0.5658 0.6667 0.6462 0.5169 0.9232 0.8311 0.626 0.9349 0.902
Cytoplasmic Foci 0.0065 0.0006 0.0027 0.0012 0.0032 0.0023 0.0267 0.0007 0.0102 0.004 0.0126 0.0055 0.02 0.0012 0.0091 0.0034 0.0018 0.0029
Eisosomes 0.001 0.0022 0 0 0 0.0001 0.0009 0 0 0.0001 0.0004 0.0001 0.0008 0.0002 0.0002 0.0002 0 0
Endoplasmic Reticulum 0.0644 0.0112 0.0286 0.0035 0.0124 0.0953 0.0228 0.004 0.0063 0.0037 0.0102 0.0481 0.0216 0.0022 0.0035 0.0021 0.001 0.0024
Endosome 0.0096 0.0014 0.0038 0.0052 0.0083 0.0108 0.0101 0.0015 0.0058 0.0212 0.0515 0.0226 0.0262 0.0006 0.0018 0.0156 0.0034 0.0091
Golgi 0.0022 0.0003 0.0005 0.0002 0.0003 0.0035 0.0038 0.0002 0.0008 0.0106 0.0248 0.0046 0.0091 0.0001 0.0015 0.0071 0.0001 0.0008
Lipid Particles 0.0063 0.0025 0.0026 0.0037 0.0007 0.0038 0.0114 0.0005 0.0021 0.0014 0.0044 0.0013 0.0182 0.0017 0.0027 0.0013 0.0004 0.0001
Mitochondria 0.0125 0.0008 0.0014 0.0016 0.0003 0.0098 0.0161 0.003 0.002 0.0212 0.0396 0.021 0.0206 0.0003 0.0027 0.015 0.0002 0.0083
None 0.0059 0.0004 0.0011 0.0005 0.0003 0.0007 0.0148 0.0002 0.0027 0.0014 0.0134 0.0024 0.019 0.0012 0.0035 0.0009 0.0005 0.0008
Nuclear Periphery 0.0378 0.0066 0.0091 0.0073 0.0188 0.0167 0.0233 0.0021 0.0086 0.0118 0.0313 0.0857 0.0424 0.004 0.0067 0.0147 0.0069 0.008
Nucleolus 0.0227 0.0005 0.0038 0.0026 0.0004 0.0005 0.0075 0.0001 0.0009 0.0025 0.0054 0.0091 0.0121 0.001 0.0044 0.0039 0.0002 0.0002
Nucleus 0.0131 0.0032 0.0049 0.0088 0.0122 0.0061 0.0134 0.0019 0.005 0.0077 0.0076 0.0178 0.0229 0.0034 0.0057 0.0133 0.0036 0.0086
Peroxisomes 0.0006 0 0.0001 0.0001 0 0.0001 0.0014 0 0.0003 0.0006 0.0014 0.0007 0.0108 0 0.0061 0.0005 0 0.0003
Punctate Nuclear 0.0011 0 0.0001 0.0001 0.0001 0.0002 0.0024 0 0.0007 0.0002 0.0011 0.0011 0.0079 0.0001 0.0003 0.0002 0.0001 0.0001
Vacuole 0.171 0.1019 0.1613 0.3688 0.1308 0.0769 0.1092 0.0484 0.1174 0.2467 0.0688 0.0666 0.1066 0.0375 0.0619 0.1954 0.0289 0.0261
Vacuole Periphery 0.0239 0.0062 0.0191 0.0707 0.0221 0.0138 0.0254 0.0053 0.0168 0.0824 0.0209 0.0414 0.0263 0.0028 0.0098 0.0682 0.0077 0.0151

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1958.2555 2149.9918 2243.453 2062.0054 2412.2951 1898.2984 1733.6295 1582.0224 1728.0096 1777.1372
Translational Efficiency 1.5698 1.4434 1.5455 1.2897 1.643 1.6888 1.5459 1.7532 1.6207 1.7016

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1154 1607 724 1153 1178 1533 2053 1018 2332 3140 2777 2171

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 7777.57 7370.16 13351.85 11659.53 7927.58 7835.78 13123.84 11475.53 7853.35 7597.48 13183.29 11573.25
Standard Deviation 1903.42 2217.52 2742.53 2909.96 2213.94 1853.35 2753.96 2990.76 2067.48 2061.02 2752.80 2949.55
Intensity Change Log 2 — -0.077624 0.779648 0.584118 — -0.016804 0.727237 0.533608 — -0.046603 0.753431 0.558843

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000071 0.000069 0.000124 0.000412 0.000040 0.000092 0.000084 0.000392 0.000055 0.000080 0.000095 0.000402
Bud Neck 0.000500 0.000325 0.005513 0.001439 0.000301 0.000560 0.000389 0.001714 0.000399 0.000440 0.001724 0.001568
Bud Site 0.000846 0.001271 0.002698 0.006335 0.000991 0.002105 0.002494 0.009606 0.000919 0.001678 0.002547 0.007869
Cell Periphery 0.020688 0.011328 0.025262 0.109702 0.024258 0.011672 0.073445 0.086548 0.022491 0.011496 0.060883 0.098845
Cytoplasm 0.636522 0.729314 0.225640 0.248412 0.659357 0.700270 0.442248 0.192297 0.648057 0.715134 0.385776 0.222099
Cytoplasmic Foci 0.009476 0.006443 0.014879 0.003379 0.006124 0.007841 0.003592 0.004092 0.007783 0.007125 0.006535 0.003713
Eisosomes 0.000003 0.000001 0.000008 0.000012 0.000002 0.000001 0.000003 0.000011 0.000002 0.000001 0.000004 0.000012
Endoplasmic Reticulum 0.000272 0.000437 0.000480 0.001286 0.000705 0.000436 0.001766 0.000822 0.000491 0.000437 0.001431 0.001068
Endosome 0.000296 0.000313 0.000689 0.000534 0.000309 0.000513 0.000513 0.002663 0.000302 0.000411 0.000559 0.001532
Golgi 0.061619 0.044610 0.051373 0.024671 0.057704 0.050339 0.017791 0.023599 0.059641 0.047407 0.026546 0.024168
Lipid Particles 0.009048 0.005176 0.017635 0.040681 0.014587 0.007355 0.024126 0.049345 0.011846 0.006240 0.022434 0.044744
Mitochondria 0.000224 0.000494 0.000273 0.000545 0.000120 0.000311 0.000323 0.003380 0.000171 0.000404 0.000310 0.001874
Mitotic Spindle 0.000439 0.000372 0.001640 0.000534 0.000389 0.000759 0.000292 0.001354 0.000414 0.000561 0.000643 0.000919
None 0.004752 0.007238 0.001085 0.002095 0.004196 0.003764 0.000932 0.001367 0.004471 0.005542 0.000972 0.001754
Nuclear Periphery 0.001281 0.000644 0.006171 0.001585 0.000953 0.000591 0.000799 0.001017 0.001115 0.000618 0.002200 0.001319
Nuclear Periphery Foci 0.013693 0.009994 0.018576 0.011090 0.013716 0.010944 0.005485 0.007452 0.013705 0.010458 0.008898 0.009384
Nucleolus 0.000260 0.000176 0.000301 0.000199 0.000106 0.000158 0.000151 0.000278 0.000182 0.000167 0.000190 0.000236
Nucleus 0.017162 0.012366 0.023942 0.008414 0.011969 0.014412 0.003525 0.005700 0.014539 0.013365 0.008848 0.007141
Peroxisomes 0.000006 0.000029 0.000014 0.000093 0.000010 0.000014 0.000281 0.000216 0.000008 0.000021 0.000211 0.000151
Vacuole 0.093244 0.075109 0.444017 0.445853 0.107644 0.108917 0.339170 0.537087 0.100518 0.091615 0.366505 0.488633
Vacuole Periphery 0.129599 0.094290 0.159680 0.092730 0.096521 0.078946 0.082591 0.071061 0.112890 0.086799 0.102689 0.082569

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.01 -5.28 -3.13 -3.12 -2.44 -2.88 -3.66 -4.82 -3.94 -4.09 -2.13 -4.42 -5.12 -4.67 -4.36
Bud Neck 1.55 -10.41 -6.86 -7.26 8.66 -4.78 -3.03 -8.29 -5.97 -7.56 -1.98 -10.01 -10.83 -9.24 2.46
Bud Site -2.15 -4.92 -7.50 -6.91 -3.38 -4.21 -4.40 -5.53 -4.72 -4.56 -4.67 -6.56 -8.33 -7.32 -6.01
Cell Periphery 5.72 -1.00 -22.48 -26.14 -21.73 7.84 -16.64 -14.99 -19.44 -2.12 9.60 -16.93 -26.60 -32.31 -11.13
Cytoplasm -7.12 28.12 27.97 39.81 -2.22 -2.72 17.38 34.38 40.82 20.23 -6.98 27.16 43.73 56.65 16.75
Cytoplasmic Foci 3.72 -4.55 6.89 3.53 7.69 -2.88 4.70 2.12 4.29 -0.97 0.99 0.54 6.45 5.60 4.99
Eisosomes 3.41 -7.98 -3.83 -4.28 -1.38 1.87 -5.57 -6.46 -6.72 -5.51 3.86 -8.49 -6.34 -6.83 -4.71
Endoplasmic Reticulum -2.13 -1.44 -8.30 -6.08 -5.58 2.17 -6.09 -0.68 -3.93 6.27 0.74 -8.07 -5.75 -7.27 2.89
Endosome -0.38 -9.41 -5.73 -5.17 4.64 -4.83 -6.64 -3.25 -2.89 -2.94 -3.89 -10.76 -3.64 -3.24 -2.74
Golgi 5.40 4.95 13.92 8.88 9.91 2.57 15.70 12.52 10.42 -3.05 5.62 18.30 18.66 13.67 1.63
Lipid Particles 4.15 -5.91 -15.39 -18.33 -10.45 5.22 -5.59 -11.39 -15.30 -8.46 6.67 -9.13 -18.20 -23.39 -12.05
Mitochondria -0.97 -2.17 -2.28 -0.32 -1.41 -2.83 -8.09 -2.39 -2.23 -2.23 -1.61 -5.52 -2.69 -2.25 -2.42
Mitotic Spindle 1.12 -4.46 -1.56 -2.93 4.14 -4.47 2.30 -1.94 -1.18 -2.11 -3.14 -3.30 -2.15 -1.48 -0.94
None -1.54 4.07 2.49 3.50 -1.56 0.41 3.71 2.79 2.55 -1.14 -1.09 5.38 3.67 4.27 -1.88
Nuclear Periphery 6.09 -6.99 -2.45 -9.82 6.59 4.46 1.57 -0.98 -6.41 -2.96 7.52 -5.67 -2.79 -11.70 4.67
Nuclear Periphery Foci 2.95 -2.99 1.94 -1.00 5.09 2.53 9.29 6.75 4.43 -3.84 3.91 6.26 5.19 1.57 -0.83
Nucleolus 1.01 -1.69 0.81 -0.56 5.11 -1.89 -2.49 -1.75 -1.16 -1.37 0.20 -0.79 -1.11 -1.30 -0.79
Nucleus 3.14 -4.73 4.15 1.61 6.47 -2.57 7.19 2.53 4.45 -3.85 -0.10 1.52 4.70 4.40 2.41
Peroxisomes -1.36 -6.27 -5.08 -2.60 -4.43 -1.20 -7.95 -2.06 -2.02 0.70 -1.55 -8.08 -3.00 -2.65 1.25
Vacuole 3.06 -31.03 -37.93 -42.14 0.48 -0.89 -29.80 -41.37 -41.32 -17.58 1.42 -42.57 -55.40 -58.15 -14.28
Vacuole Periphery 5.05 -1.45 5.78 0.82 7.87 3.54 2.91 5.43 2.16 3.96 6.05 3.60 7.65 1.84 5.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Rpl26b

Rpl26b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl26b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available