Standard name
Human Ortholog
Description Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation; relocalizes from nucleus to cytoplasm upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.77 0.78 0.9 0.47 0.75 0.72 0.8 0.79 0.57 0.66 0.55 0.65 0.89 0.98 0.99 – – – 0.6 0.57 0.62 0.76 0.84 0.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0.08 0.12 0 0.08 0 0.19 0.21 0.16 0.54 0.36 0.49 0.4 0 0 0 – – – 0 0.05 0.06 0 0 0
Nucleus 0.12 0.09 0.05 0.39 0.1 0.13 0.06 0.05 0.05 0.06 0.08 0 0.14 0 0 – – – 0.15 0.12 0.08 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0.05 0 0 0 0 0.07
Vac/Vac Membrane 0.13 0.07 0.08 0.07 0.14 0.07 0 0.05 0 0 0 0 0 0 0 – – – 0.09 0.14 0.1 0.12 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 – – – 2 3 5 0 0 1
Bud 1 0 0 1 1 3 1 3 8 6 3 9 0 0 0 – – – 6 8 4 0 0 3
Bud Neck 1 4 3 4 6 7 10 15 8 12 10 9 0 1 0 – – – 1 4 0 0 0 0
Bud Site 0 0 0 2 0 1 1 0 5 3 5 2 0 0 0 – – – – – – – – –
Cell Periphery 0 1 1 0 1 0 2 2 1 2 2 1 0 0 0 – – – 0 1 1 0 0 0
Cytoplasm 157 347 247 97 229 258 180 391 261 279 294 341 25 203 199 – – – 134 274 182 38 132 149
Endoplasmic Reticulum 1 0 1 2 0 1 1 0 3 2 1 0 0 0 0 – – – 0 1 0 0 0 1
Endosome 1 0 1 1 5 2 0 3 1 0 1 1 0 0 0 – – – 3 2 3 1 1 2
Golgi 1 1 0 1 0 0 0 1 0 0 0 0 0 0 0 – – – 2 3 1 0 0 0
Mitochondria 16 52 3 16 13 70 47 79 249 152 262 211 0 0 0 – – – 4 23 18 0 4 5
Nucleus 25 42 13 80 32 48 14 24 23 25 44 23 4 0 1 – – – 33 57 22 0 2 0
Nuclear Periphery 0 0 0 0 0 0 0 1 0 1 1 0 0 1 0 – – – 0 1 1 0 0 0
Nucleolus 0 0 0 1 1 0 0 0 1 0 0 1 0 1 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 1 1 1 1 1 0 6 5 4 7 6 0 0 1 – – – 11 18 8 0 2 12
Vac/Vac Membrane 26 31 21 14 44 25 0 26 16 15 17 21 0 2 2 – – – 19 68 30 6 7 4
Unique Cell Count 205 447 275 207 307 360 224 492 459 423 537 521 28 207 200 224 482 292 51 158 188
Labelled Cell Count 229 479 291 220 333 416 256 551 583 502 647 625 29 208 203 224 482 292 51 158 188


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 3.4 5.0 4.8 5.0 4.0 3.0 4.3 3.1 3.5 3.5 3.6 4.4 4.7 4.3 – – – 5.4 5.5 5.4
Std Deviation (1e-4) 0.9 0.7 1.5 1.0 1.4 1.0 0.6 1.2 0.6 0.7 0.9 0.9 0.5 1.9 1.3 – – – 1.7 2.0 2.1
Intensity Change (Log2) – – – -0.07 0.0 -0.34 -0.76 -0.22 -0.69 -0.51 -0.54 -0.49 -0.18 -0.09 -0.22 – – – 0.1 0.12 0.11


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.7543 1.8749 1.2002 0.9787 0.8794 1.7646 2.6257 2.5788 2.7247 2.0435 2.2661 3.3025 0.6374 0.8477 0.5331 0.635 0.7044 0.9963
Actin 0.0801 0.0002 0.0065 0.0434 0.0013 0.0056 0.0131 0.0051 0.0083 0.0001 0.003 0.0008 0.0013 0.0002 0.0002 0.0002 0.0001 0.0002
Bud 0.0008 0.0013 0.0003 0.0004 0.0001 0.0002 0.001 0.0002 0.0022 0.0053 0.0156 0.0001 0.0001 0.0005 0.0016 0.001 0 0.0001
Bud Neck 0.0119 0.0006 0.0003 0.0002 0.0001 0.0048 0.0098 0.0004 0.0008 0.0003 0.0012 0.0026 0.0006 0.0004 0.0003 0.0005 0 0.002
Bud Periphery 0.0013 0.0019 0.0007 0.0007 0.0001 0.0005 0.0018 0.0002 0.0037 0.0118 0.0166 0.0001 0.0001 0.0003 0.0008 0.0026 0 0.0001
Bud Site 0.0179 0.0069 0.0005 0.0005 0.0002 0.0006 0.0044 0.0031 0.0023 0.0003 0.002 0.0001 0.0003 0.006 0.0019 0.0003 0 0.0001
Cell Periphery 0.0008 0.0004 0.0002 0.0001 0 0.0004 0.0006 0.0002 0.0002 0.0003 0.0004 0 0.0001 0.0001 0.0001 0.0001 0 0
Cytoplasm 0.0822 0.1474 0.0826 0.0663 0.0639 0.1246 0.1174 0.0527 0.063 0.0233 0.0565 0.0601 0.1433 0.1327 0.0759 0.0951 0.026 0.1331
Cytoplasmic Foci 0.0321 0.0023 0.007 0.0029 0.0055 0.0086 0.0196 0.0016 0.0074 0.0011 0.0037 0.0059 0.0075 0.0024 0.0079 0.0021 0.0034 0.0028
Eisosomes 0.0008 0.0002 0.0004 0.0003 0.0001 0.0003 0.0002 0.0001 0.0004 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0062 0.0028 0.0039 0.0008 0.0007 0.0014 0.0042 0.0016 0.0026 0.0008 0.0024 0.0009 0.0028 0.0019 0.0012 0.0021 0.0002 0.0013
Endosome 0.0232 0.0016 0.003 0.0005 0.0037 0.003 0.0072 0.0006 0.0043 0.0002 0.0107 0.0012 0.0029 0.0009 0.0008 0.001 0.0001 0.0012
Golgi 0.0103 0.0001 0.0026 0.0008 0.002 0.0015 0.0019 0.0001 0.0017 0 0.0009 0.0001 0.0002 0 0.0001 0 0 0
Lipid Particles 0.0211 0.0002 0.003 0.001 0.0171 0.007 0.003 0.0002 0.0024 0.0001 0.0015 0.0005 0.0038 0.0001 0.0003 0.0001 0.0001 0.0001
Mitochondria 0.0169 0.001 0.0015 0.0061 0.0041 0.0025 0.0017 0.0005 0.0024 0.0032 0.0017 0.0003 0.0013 0.0005 0.0009 0.0009 0.0001 0.0003
None 0.2691 0.5949 0.7924 0.8038 0.8334 0.3929 0.5559 0.417 0.817 0.8967 0.8123 0.5465 0.4075 0.6624 0.8012 0.8481 0.9676 0.4628
Nuclear Periphery 0.018 0.0076 0.0071 0.0015 0.0042 0.0039 0.0077 0.0076 0.0085 0.0028 0.0129 0.0032 0.0151 0.0054 0.0019 0.0031 0.0002 0.0039
Nucleolus 0.0025 0.0048 0.0009 0.0004 0.0002 0.0044 0.004 0.0059 0.001 0.0014 0.0026 0.0053 0.0033 0.0018 0.0017 0.0026 0.0001 0.0042
Nucleus 0.3357 0.2157 0.0711 0.0442 0.0332 0.4177 0.2082 0.4819 0.0608 0.0464 0.0429 0.352 0.3967 0.1751 0.0949 0.0343 0.0009 0.3689
Peroxisomes 0.0317 0.0001 0.0104 0.024 0.0281 0.0113 0.0047 0.0002 0.0021 0.0001 0.0008 0.0008 0.0002 0.0001 0.0005 0.0001 0.0001 0.0001
Punctate Nuclear 0.0281 0.0049 0.0036 0.0014 0.0014 0.0073 0.0222 0.0203 0.0062 0.0003 0.0054 0.0184 0.0109 0.007 0.0061 0.0029 0.0009 0.0176
Vacuole 0.0076 0.0046 0.0018 0.0008 0.0003 0.0013 0.0104 0.0005 0.0017 0.0036 0.0057 0.0006 0.0014 0.0017 0.0014 0.0022 0.0001 0.0009
Vacuole Periphery 0.0018 0.0005 0.0003 0.0002 0.0002 0.0003 0.0011 0.0001 0.0008 0.0018 0.0011 0.0001 0.0006 0.0002 0.0002 0.0005 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.4987 5.4617 8.9161 51.4318 34.0622 8.5488 5.7984 6.3362 33.0744 47.7485
Translational Efficiency 0.9361 0.542 1.3085 0.8159 1.0852 0.6931 0.5344 0.7449 1.1362 0.9136

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1988 1393 128 1840 1492 2409 270 1524 3480 3802 398 3364

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 697.44 721.93 864.49 826.92 656.16 798.22 862.86 829.23 679.74 770.27 863.38 827.97
Standard Deviation 75.03 114.97 102.02 111.13 67.92 90.10 105.18 111.34 74.90 106.48 104.18 111.23
Intensity Change Log 2 — 0.049790 0.309780 0.245679 — 0.282739 0.395079 0.337725 — 0.167412 0.351759 0.291032

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000137 0.000280 0.000353 0.000493 0.000071 0.000144 0.000285 0.000510 0.000109 0.000194 0.000307 0.000501
Bud Neck 0.011470 0.023858 0.001735 0.015056 0.007915 0.023855 0.002668 0.009833 0.009946 0.023856 0.002368 0.012690
Bud Site 0.002549 0.011176 0.008186 0.028893 0.002554 0.008986 0.001543 0.027306 0.002551 0.009788 0.003679 0.028174
Cell Periphery 0.000095 0.000217 0.000165 0.000183 0.000102 0.000218 0.000098 0.000257 0.000098 0.000218 0.000120 0.000217
Cytoplasm 0.424983* 0.381197* 0.114640* 0.274224* 0.464133* 0.423818* 0.087984 0.310024* 0.441768* 0.408202* 0.096557 0.290443*
Cytoplasmic Foci 0.122637 0.189469* 0.008644 0.007863 0.133219 0.106537 0.004580 0.013889 0.127174 0.136922 0.005887 0.010593
Eisosomes 0.000085 0.000138 0.000066 0.000036 0.000079 0.000106 0.000044 0.000044 0.000082 0.000117 0.000051 0.000039
Endoplasmic Reticulum 0.000788 0.001356 0.004792 0.004940 0.000405 0.000553 0.006095 0.005309 0.000624 0.000847 0.005676 0.005107
Endosome 0.003999 0.013504 0.001537 0.002755 0.003749 0.006274 0.002291 0.003266 0.003891 0.008923 0.002048 0.002986
Golgi 0.000908 0.003466 0.000052 0.000487 0.001067 0.002265 0.000122 0.003927 0.000976 0.002705 0.000099 0.002046
Lipid Particles 0.006854 0.006719 0.002244 0.000932 0.004551 0.004083 0.001170 0.001257 0.005867 0.005049 0.001516 0.001079
Mitochondria 0.003683 0.009637 0.000544 0.002204 0.005552 0.006221 0.000415 0.002212 0.004485 0.007472 0.000456 0.002208
Mitotic Spindle 0.000769 0.002755 0.000183 0.030866 0.001912 0.004274 0.001985 0.014670 0.001259 0.003717 0.001406 0.023528
None 0.004591 0.011051 0.003978 0.006002 0.004554 0.004707 0.005333 0.006579 0.004575 0.007032 0.004897 0.006264
Nuclear Periphery 0.000807 0.000589 0.001430 0.002742 0.000575 0.000493 0.001585 0.002367 0.000708 0.000529 0.001535 0.002572
Nuclear Periphery Foci 0.000264 0.000503 0.000658 0.001015 0.000247 0.000142 0.000696 0.001272 0.000257 0.000274 0.000684 0.001131
Nucleolus 0.001702 0.003745 0.000990 0.001179 0.001356 0.001631 0.000562 0.001269 0.001553 0.002406 0.000699 0.001220
Nucleus 0.378634* 0.284450* 0.814331* 0.567768* 0.344049* 0.371300* 0.849713* 0.525481* 0.363806* 0.339479* 0.838334* 0.548611*
Peroxisomes 0.003913 0.011092 0.000288 0.000671 0.002822 0.005479 0.000247 0.000311 0.003445 0.007535 0.000260 0.000508
Vacuole 0.030732 0.043166 0.035023 0.050755 0.020704 0.028184 0.032225 0.067114 0.026432 0.033673 0.033125 0.058166
Vacuole Periphery 0.000400 0.001631 0.000163 0.000935 0.000385 0.000730 0.000359 0.003103 0.000394 0.001060 0.000296 0.001917

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.69 -3.54 -6.42 -5.32 -1.35 -2.16 -6.73 -7.31 -6.03 -2.02 -2.48 -6.53 -9.53 -8.48 -2.54
Bud Neck -6.53 10.01 -3.66 3.87 -13.80 -9.61 4.00 -4.32 5.38 -7.77 -11.01 8.91 -5.49 6.47 -13.89
Bud Site -7.66 -0.78 -8.76 -3.93 -2.29 -5.59 0.79 -7.27 -4.24 -7.58 -8.87 -0.55 -11.34 -5.97 -7.08
Cell Periphery -7.09 -3.93 -6.68 3.88 1.64 -7.41 -1.47 -3.18 0.89 -2.45 -10.25 -3.97 -5.19 2.97 -1.59
Cytoplasm 4.58 19.63 25.91 18.12 -6.76 4.38 35.69 22.01 19.78 -16.14 5.11 40.74 33.69 28.57 -16.66
Cytoplasmic Foci -9.74 20.67 29.98 31.85 1.31 4.85 27.93 25.88 27.10 -5.99 -2.18 37.55 39.53 41.22 -1.92
Eisosomes -7.06 -0.33 6.68 11.72 2.93 -3.96 1.94 1.77 5.61 -0.80 -7.00 1.62 6.08 11.80 1.70
Endoplasmic Reticulum -3.39 -8.39 -20.06 -17.92 -0.66 -2.28 -10.73 -21.64 -20.93 2.52 -2.53 -12.67 -29.20 -28.50 2.31
Endosome -8.45 2.09 2.42 9.51 -0.52 -3.84 1.72 -0.15 3.99 -1.90 -8.80 2.52 1.60 10.10 -1.65
Golgi -6.59 5.00 3.95 8.63 -1.75 -2.39 3.40 -0.89 0.66 -2.35 -5.24 5.82 0.09 4.04 -2.65
Lipid Particles 0.16 4.63 8.39 8.94 3.03 0.82 5.66 5.31 6.40 -1.37 1.60 8.03 9.88 11.23 1.86
Mitochondria -4.29 6.37 3.56 6.00 -8.80 -0.49 3.83 2.88 6.03 -4.82 -3.28 6.32 4.18 8.53 -9.57
Mitotic Spindle -2.32 -0.59 -11.41 -10.48 -10.49 -1.93 0.28 -7.17 -6.18 -7.03 -3.19 -0.31 -13.46 -11.94 -12.64
None -4.12 1.46 -4.36 2.82 -3.83 -0.26 0.53 -2.03 -1.87 -1.85 -3.66 1.12 -4.38 1.05 -3.61
Nuclear Periphery 2.05 -5.13 -21.46 -24.90 -13.83 0.71 -8.85 -18.20 -21.99 -5.76 2.36 -9.88 -27.91 -33.14 -12.63
Nuclear Periphery Foci -4.03 -2.72 -7.47 -7.06 -4.42 2.25 -4.81 -7.02 -7.16 -5.64 -0.53 -5.21 -10.24 -10.21 -7.56
Nucleolus -3.97 1.52 -4.59 -1.67 -5.09 -0.69 3.54 -4.84 -4.61 -6.07 -3.07 4.55 -6.64 -4.99 -8.26
Nucleus 9.45 -15.50 -18.66 -25.52 8.29 -2.92 -31.78 -16.41 -14.74 19.10 3.59 -34.27 -24.69 -27.60 19.83
Peroxisomes -6.91 1.70 5.99 11.54 0.68 -3.94 6.44 5.44 8.87 -4.19 -6.92 5.21 7.91 14.21 -0.02
Vacuole -5.16 -2.95 -17.81 -13.89 -1.88 -4.25 -5.73 -20.25 -18.67 -5.93 -4.96 -5.83 -26.72 -24.08 -5.53
Vacuole Periphery -6.96 5.54 -0.31 5.57 -2.10 -5.34 0.68 -2.33 -1.55 -2.43 -8.75 1.35 -2.30 0.75 -2.69
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation; relocalizes from nucleus to cytoplasm upon DNA replication stress
Localization
Cell Percentages cytoplasm (26%), nucleus (12%), mixed (43%)
Cell Cycle Regulation Yes
cytoplasm - MA (3.3e-05)
nucleus - T/G1 (2.4e-05)
Subcompartmental Group N/A

Rme1

Rme1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rme1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available