Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0.06 0.06 0.07 0.06 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.09 0.1 0.12 0.09 0.11 0 0.07 0.05 0.06 0.05 0 0.15 0.21 0.24 0.09 0.17 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.07 0.33 0.42 0.28 0.47 0.63 0.58 0.7 0.7 0.67 0.75 0 0 0.07 0 0 0.07 0 0 0 0 0 0
Nucleus 0.8 0.66 0.61 0.68 0.66 0.63 0.59 0.6 0.6 0.58 0.55 0.48 0.78 0.71 0.67 0.78 0.7 0.72 0.7 0.67 0.53 0.63 0.5 0.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.06 0.05 0.12 0.16 0.18 0.17 0.18 0.19 0 0 0 0 0 0 0.06 0 0.05 0.06 0.11 0.08
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.05 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0.05 0.07 0.07
Vac/Vac Membrane 0.17 0.23 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0.13 0.14 0.16 0.09 0.14 0.19 0.14 0.16 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 2
Bud 0 0 1 3 3 3 6 9 4 7 14 4 0 0 2 0 0 0 1 3 4 5 4 9
Bud Neck 0 0 2 0 1 0 2 2 0 1 2 0 0 0 0 0 0 0 0 2 1 1 2 3
Bud Site 0 0 2 3 8 9 18 28 16 27 14 18 0 0 2 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 0 0 0 0 0 0 0 0 0
Cytoplasm 1 29 34 24 30 33 18 33 14 23 13 14 34 97 109 17 23 17 2 13 18 7 2 6
Endoplasmic Reticulum 0 2 2 0 0 0 0 0 0 0 0 0 1 0 0 12 4 5 0 1 4 2 1 4
Endosome 1 11 3 0 12 1 0 0 0 0 0 0 2 17 8 7 6 4 4 8 9 5 21 44
Golgi 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 3 0 2 0 1
Mitochondria 2 23 109 83 92 137 255 283 197 261 163 243 7 5 30 4 1 10 1 8 14 0 9 18
Nucleus 98 218 198 134 217 183 240 292 170 214 134 156 177 325 307 152 97 110 111 263 228 141 156 184
Nuclear Periphery 0 1 0 0 0 1 0 1 1 2 5 5 0 0 0 0 0 1 0 1 1 0 0 6
Nucleolus 3 3 1 3 18 15 48 79 51 63 44 62 4 12 15 1 0 2 9 16 21 12 35 36
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0
SpindlePole 2 1 7 5 17 6 15 18 13 6 3 6 3 16 12 0 0 3 7 12 28 10 21 31
Vac/Vac Membrane 21 76 20 2 11 6 4 5 2 1 4 2 6 13 10 25 20 24 14 54 83 30 50 90
Unique Cell Count 123 330 326 196 327 290 404 487 282 372 242 322 227 456 457 195 139 153 158 395 429 225 315 461
Labelled Cell Count 129 365 379 258 409 394 606 751 468 605 396 510 234 488 501 218 153 177 158 395 429 225 315 461


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.9 5.3 4.3 4.4 4.6 4.3 3.8 3.9 3.7 3.7 3.8 3.5 5.8 5.8 5.2 8.2 9.2 8.7 5.7 6.2 6.6
Std Deviation (1e-4) 1.1 1.1 1.0 1.5 1.6 1.8 1.2 1.3 1.2 1.4 1.2 1.1 1.2 1.3 1.2 1.3 1.9 1.6 1.5 1.8 1.8
Intensity Change (Log2) – – – 0.0 0.09 -0.01 -0.18 -0.14 -0.21 -0.22 -0.19 -0.3 0.41 0.43 0.26 0.91 1.09 1.01 0.4 0.51 0.6

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.6 -0.5 0.4 -3.1 -1.9 -2.5 -2.0 -2.2 -3.0 1.6 4.0 4.8 -0.6 1.8 0.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.8 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 2.5 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -8.6 -12.6 -9.7 -8.4 -7.6 -6.4
Nucleus 1.8 1.5 0.6 -0.4 -0.2 -0.1 -0.9 -1.3 -3.1 4.3 3.1 1.9 4.0 1.9 2.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 2.5 2.9 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 1.1 0.4 0 0 0
Vacuole -2.8 -1.7 -2.5 -3.9 -4.1 -3.6 -4.5 -2.6 -3.9 -1.9 -2.3 -2.8 2.6 2.9 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.7614 2.4163 2.3254 2.0075 1.9527 2.0827 0.3124 0.8096 0.7562 0.3185 0.5264 0.6374 5.2428 5.4428 5.274 5.8953 4.9385 5.3961
Actin 0.0275 0.001 0.0107 0.0021 0.0147 0.0021 0.0008 0 0 0 0 0.0002 0.0002 0 0.005 0.0002 0.0013 0
Bud 0.0006 0.0004 0.0007 0.0002 0.0007 0.0001 0 0 0 0 0 0 0.0001 0 0.0001 0 0.0001 0
Bud Neck 0.0053 0.0008 0.0024 0.0008 0.0076 0.0038 0.0002 0.0002 0.0002 0.0001 0.0006 0.0014 0.0043 0.0003 0.0004 0.0003 0.0027 0.0016
Bud Periphery 0.0016 0.001 0.0017 0.0009 0.001 0.0002 0.0001 0 0 0 0 0 0.0006 0 0.0001 0 0.0001 0
Bud Site 0.0048 0.0011 0.0083 0.0004 0.0096 0.0003 0 0.0001 0.0001 0 0 0.0001 0.0002 0.0003 0.0006 0.0001 0.0003 0.0001
Cell Periphery 0.0005 0.0001 0.0009 0.0002 0.0002 0 0 0 0 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0048 0.0112 0.0032 0.0158 0.0084 0.0013 0.0008 0.0044 0.0007 0.0002 0.0021 0.0014 0.0043 0.0105 0.0053 0.0118 0.0088 0.0035
Cytoplasmic Foci 0.0129 0.0004 0.0044 0.0006 0.0076 0.001 0.0002 0.0001 0.0001 0 0 0.0007 0.001 0.0003 0.0004 0.0003 0.003 0.0001
Eisosomes 0.0003 0 0.0002 0.0001 0.0002 0 0 0 0 0 0 0 0 0 0.0001 0 0 0
Endoplasmic Reticulum 0.007 0.0014 0.002 0.0015 0.002 0.0003 0.0002 0.0002 0 0 0.0001 0.0001 0.0003 0.0005 0.0002 0.0006 0.0003 0.0002
Endosome 0.0156 0.0016 0.0253 0.002 0.0164 0.0041 0.0005 0.0004 0.0001 0 0.0001 0.0004 0.0009 0.001 0.0003 0.0018 0.0091 0.0002
Golgi 0.0111 0.0002 0.0071 0.0014 0.0169 0.0021 0.0001 0 0 0 0 0.0001 0.0001 0 0.0002 0 0.0076 0
Lipid Particles 0.0092 0.0002 0.0039 0.0027 0.0187 0.0017 0.0004 0 0 0 0 0.0001 0.0008 0.0002 0.0004 0.0002 0.032 0
Mitochondria 0.0083 0.0012 0.0142 0.0614 0.018 0.0107 0.0006 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0002 0.0006 0.0017 0.0001
None 0.007 0.0066 0.0007 0.0018 0.0009 0.0003 0.0005 0.0009 0.0002 0.0001 0.0002 0.0003 0.0139 0.0044 0.0007 0.0169 0.0607 0.0028
Nuclear Periphery 0.0228 0.0125 0.014 0.0045 0.0106 0.0024 0.0032 0.0124 0.002 0.0005 0.0036 0.002 0.0016 0.0063 0.0036 0.0078 0.002 0.0015
Nucleolus 0.0251 0.0151 0.0192 0.0166 0.0249 0.0316 0.0107 0.0113 0.0145 0.0041 0.0137 0.0183 0.0135 0.0117 0.0203 0.0097 0.0394 0.0247
Nucleus 0.7971 0.9231 0.8423 0.8502 0.7997 0.9124 0.9655 0.9553 0.9609 0.9682 0.9713 0.9608 0.9324 0.9523 0.9316 0.9361 0.8139 0.9331
Peroxisomes 0.0107 0.0001 0.0016 0.0089 0.0093 0.0004 0.0001 0 0 0 0 0.0001 0.0002 0 0.0023 0.0001 0.002 0
Punctate Nuclear 0.0228 0.0196 0.0284 0.0242 0.03 0.0244 0.0156 0.0142 0.0209 0.0268 0.0082 0.0137 0.0248 0.0112 0.028 0.0124 0.0143 0.0319
Vacuole 0.003 0.0019 0.0064 0.0018 0.0014 0.0004 0.0002 0.0002 0.0001 0 0.0001 0.0001 0.0005 0.0006 0.0003 0.0009 0.0003 0.0002
Vacuole Periphery 0.0019 0.0004 0.0024 0.0018 0.0009 0.0003 0.0002 0.0001 0 0 0 0 0.0001 0.0001 0.0001 0.0002 0.0003 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.6223 13.7798 12.1276 14.1708 12.0844 13.2565 13.8517 11.6999 15.4679 16.5048
Translational Efficiency 0.9389 0.8675 0.7973 0.7881 0.8811 0.845 0.8507 0.7939 0.6361 0.7021

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1683 855 217 250 1393 1583 1490 122 3076 2438 1707 372

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 675.67 804.36 1135.25 987.14 705.99 787.28 954.22 990.16 689.40 793.27 977.23 988.13
Standard Deviation 82.39 114.84 128.82 126.22 100.23 106.98 123.34 122.61 92.15 110.10 137.93 125.06
Intensity Change Log 2 — 0.251523 0.748619 0.546936 — 0.157229 0.434674 0.488014 — 0.204111 0.596734 0.517129

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000049 0.000788 0.001392 0.001579 0.000212 0.000740 0.000671 0.001986 0.000123 0.000757 0.000763 0.001712
Bud Neck 0.001924 0.004720 0.008332 0.021073 0.003449 0.005045 0.016464 0.033321 0.002615 0.004931 0.015431 0.025090
Bud Site 0.000584 0.001825 0.003941 0.014257 0.000769 0.001646 0.002787 0.013528 0.000668 0.001709 0.002934 0.014018
Cell Periphery 0.000092 0.000149 0.000357 0.000336 0.000101 0.000097 0.000110 0.000369 0.000096 0.000115 0.000142 0.000347
Cytoplasm 0.249913 0.083616 0.016955 0.042349 0.077563 0.068353 0.010046 0.037722 0.171862 0.073705 0.010925 0.040832
Cytoplasmic Foci 0.013864 0.012077 0.000275 0.003767 0.007731 0.006842 0.000094 0.001820 0.011087 0.008678 0.000117 0.003128
Eisosomes 0.000020 0.000044 0.000037 0.000035 0.000028 0.000028 0.000024 0.000051 0.000023 0.000034 0.000026 0.000040
Endoplasmic Reticulum 0.000675 0.004193 0.009017 0.006359 0.001941 0.002431 0.005851 0.012087 0.001248 0.003049 0.006254 0.008237
Endosome 0.000835 0.002584 0.000593 0.006459 0.000773 0.001122 0.000376 0.002137 0.000807 0.001635 0.000404 0.005042
Golgi 0.000162 0.001521 0.000129 0.000694 0.000496 0.000352 0.000071 0.000582 0.000314 0.000762 0.000078 0.000657
Lipid Particles 0.001360 0.003182 0.000455 0.000480 0.002176 0.001951 0.000166 0.000937 0.001730 0.002383 0.000203 0.000630
Mitochondria 0.000569 0.005341 0.001178 0.002455 0.002978 0.003570 0.001939 0.002076 0.001660 0.004191 0.001842 0.002331
Mitotic Spindle 0.002539 0.003913 0.001905 0.057245 0.003275 0.006463 0.006032 0.105435 0.002872 0.005568 0.005508 0.073049
None 0.029284 0.011815 0.009950 0.019718 0.015923 0.008805 0.004291 0.024110 0.023233 0.009861 0.005010 0.021159
Nuclear Periphery 0.000552 0.001251 0.000809 0.001043 0.001956 0.001896 0.001478 0.001872 0.001188 0.001670 0.001393 0.001315
Nuclear Periphery Foci 0.000857 0.002254 0.000622 0.000592 0.001340 0.001026 0.000566 0.001230 0.001075 0.001457 0.000573 0.000801
Nucleolus 0.007549 0.013036 0.002472 0.002694 0.019475 0.009562 0.003610 0.007764 0.012949 0.010780 0.003465 0.004357
Nucleus 0.685860 0.839480 0.929990 0.805472 0.856907 0.873931 0.941922 0.723640 0.763321 0.861849 0.940405 0.778635
Peroxisomes 0.000351 0.002581 0.000227 0.000895 0.001227 0.001791 0.000123 0.004846 0.000748 0.002068 0.000136 0.002191
Vacuole 0.002847 0.004455 0.011230 0.012218 0.001431 0.003649 0.003139 0.024149 0.002206 0.003932 0.004167 0.016131
Vacuole Periphery 0.000114 0.001177 0.000133 0.000281 0.000248 0.000698 0.000239 0.000339 0.000175 0.000866 0.000226 0.000300

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.34 -9.05 -10.08 -4.30 -2.08 -1.15 -14.80 -7.94 -3.35 -5.41 -2.41 -20.57 -12.62 -4.33 -7.19
Bud Neck -3.83 -5.57 -6.61 -5.90 -3.45 -2.48 -11.87 -5.41 -5.04 -2.09 -4.66 -13.41 -8.39 -7.61 -3.18
Bud Site -4.64 -4.57 -5.02 -4.40 -2.82 -2.73 -5.80 -7.67 -6.97 -5.98 -4.72 -7.40 -7.10 -6.39 -5.35
Cell Periphery -4.99 -1.71 -2.96 -1.45 0.15 0.35 -0.53 -2.63 -2.71 -2.47 -2.79 -2.05 -3.81 -3.10 -2.72
Cytoplasm 19.78 33.83 31.48 8.98 -1.38 1.64 16.09 11.14 10.81 -3.22 19.08 37.82 30.28 13.22 -4.36
Cytoplasmic Foci 1.55 12.55 10.32 6.60 -1.57 1.63 8.92 8.24 8.24 -2.35 3.22 15.48 12.61 9.33 -2.20
Eisosomes -7.61 -5.05 -7.46 -2.23 -3.40 0.70 1.34 -5.98 -6.23 -6.62 -4.81 -3.08 -9.09 -6.37 -8.06
Endoplasmic Reticulum -11.61 -9.92 -11.27 -5.85 0.20 -1.84 -16.56 -7.03 -6.69 -3.68 -9.62 -23.09 -12.59 -9.80 -3.91
Endosome -2.19 0.60 -1.81 -0.22 -1.93 -1.57 2.74 -3.54 -2.34 -5.00 -2.57 3.25 -2.30 -1.17 -2.80
Golgi -2.79 0.09 -2.62 2.07 -3.07 0.68 1.75 -0.36 -1.75 -5.00 -1.79 2.07 -1.43 0.94 -5.90
Lipid Particles -3.20 3.81 3.15 4.95 -1.34 1.21 9.06 5.68 4.43 -5.59 -1.97 9.67 6.40 7.12 -6.54
Mitochondria -4.20 -5.64 -5.88 2.42 -3.27 -0.55 1.23 0.14 0.95 -2.26 -3.72 -0.61 -2.15 2.57 -1.86
Mitotic Spindle -0.74 0.07 -5.51 -5.42 -5.52 -1.33 -1.95 -6.45 -6.35 -6.29 -1.73 -2.39 -8.29 -8.09 -7.93
None 7.37 7.76 5.20 -0.86 -2.58 4.92 9.59 0.90 -1.35 -2.93 9.50 15.23 4.39 -2.04 -5.35
Nuclear Periphery -6.30 -5.67 -8.96 -5.31 -5.39 -0.03 0.46 -4.39 -4.43 -4.83 -2.60 -2.32 -7.85 -5.26 -4.91
Nuclear Periphery Foci -1.99 0.45 -2.05 1.10 -2.24 2.02 2.83 -1.43 -2.09 -2.39 -0.89 2.19 -2.04 -1.10 -3.17
Nucleolus -2.86 1.72 -2.47 -0.94 -3.24 6.64 10.63 -0.44 -2.57 -3.58 3.18 9.65 -1.41 -2.77 -5.20
Nucleus -13.84 -20.20 -4.62 3.09 6.87 -2.81 -12.01 6.82 7.59 9.68 -14.78 -28.62 1.71 7.72 12.21
Peroxisomes -3.27 1.71 -1.20 2.05 -1.76 -1.17 4.75 0.03 0.75 -1.90 -3.54 5.35 -0.62 2.11 -2.73
Vacuole -2.31 -4.54 -4.89 -4.39 -1.28 -3.61 -6.42 -5.08 -4.77 -4.54 -3.47 -6.51 -7.06 -6.54 -5.78
Vacuole Periphery -2.15 -2.83 -3.78 1.85 -2.01 -1.17 0.64 -1.37 0.99 -1.77 -2.29 -0.60 -3.12 1.95 -1.30
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102
Localization
Cell Percentages nucleus (81%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Tfc4

Tfc4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tfc4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available